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儿童系统性红斑狼疮
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  children with systemic lupus erythematosus
     Clinical and Renal Pathological Analysis on 54 Children with Systemic Lupus Erythematosus
     儿童系统性红斑狼疮54例临床及肾脏病理分析
短句来源
     Analysis of Clinical and Renal Pathological on 30 Children with Systemic Lupus Erythematosus
     儿童系统性红斑狼疮30例临床及肾脏病理分析
短句来源
     Objective To evaluate the efficacy and indications of intravenous immunoglobulin(IVIG)in children with systemic lupus erythematosus (SLE).
     目的 探讨采用静脉注射大剂量丙种球蛋白 (IVIG)治疗儿童系统性红斑狼疮 (SLE)的疗效及适应症。
短句来源
     Objective To investigate the effect of high dose intravenous immunoglobulins (IVIG) on children with systemic lupus erythematosus.
     目的 观察大剂量静脉注射免疫球蛋白 (IVIG)治疗儿童系统性红斑狼疮 (SLE)的疗效。
短句来源
     Association of HLA-A, B, and DR haplotypes with genotype in Chinese children with systemic lupus erythematosus
     儿童系统性红斑狼疮与HLA基因单倍型和基因型的相关性及家系分析
短句来源
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  sle in children
     A CLINICAL ANALYSIS OF 15 CASES SLE IN CHILDREN
     儿童系统性红斑狼疮附15例临床分析
短句来源
     Clinical analysis of 20 cases SLE in children
     儿童系统性红斑狼疮20例临床分析
短句来源
     Study on the correlation between HLA-A, B, DR alleles and SLE in children
     儿童系统性红斑狼疮与人类白细胞抗原-A、B、DR等位基因的相关性研究
短句来源
     Methods 18 cases of SLE in children were reported.
     方法 对 18例儿童系统性红斑狼疮与 5 4例成年人患者的临床特点进行对照研究。
短句来源
     Methods:15cases of SLE in children were reported. Their clinical manifestations,laboratory findings,involvement of organs,SLEDAI score were analysed detailly.
     方法:统计15例诊断明确的儿童系统性红斑狼疮的临床资料、器官系统受损数 ,并用SLE疾病活动性指数 (SLEDAI)记分对其量化。
短句来源
  “儿童系统性红斑狼疮”译为未确定词的双语例句
     Objective To study the correlation between HLA A,B,DR alleles and systemic lupus erythematosus (SLE) in children.
     目的 研究儿童系统性红斑狼疮 (SLE)与人类白细胞抗原 (HLA) A、B、DR等位基因的相关性。
短句来源
     Analysis of 18 Cases of Systemic Lupus Erythematosus in Children
     儿童系统性红斑狼疮18例分析
短句来源
     Clinical Analysis of 51 Cases of Systemic Lupus Erythematosus in Children
     儿童系统性红斑狼疮51例临床分析
短句来源
     Clinical retrospective analysis of 32 systemic lupus erythematosus in Chinese children
     儿童系统性红斑狼疮32例临床分析
短句来源
     Objective To compare the serum levels of anti β 2 glycoprotein Ⅰ(β 2 GPⅠ) antibodies with that of anticardiolipin(aCL) antibodies in SLE patients with Secondary Anti Phospholipid Syndrome(SAPS) and without SAPS(WSAPS).
     目的 通过分析伴有继发性抗磷脂综合征和无抗磷脂综合征的儿童系统性红斑狼疮 (SLE)血清的抗 β2 糖蛋白I( β2 GPⅠ )抗体亚型 ,对其抗心磷脂 (aCL)抗体亚型及抗磷脂综合征的临床症状进行评价。
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  children with systemic lupus erythematosus
Autoimmune mechanisms in children with systemic lupus erythematosus
      
Quality of life in children with systemic lupus erythematosus
      
Antiphospholipid antibodies in children with systemic lupus erythematosus: a prospective study in northern India
      
Twenty-seven children with systemic lupus erythematosus (SLE) were tested for antiphospholipid antibodies (APLA), i.e.
      
The effects of short-course plasma exchange (PE) followed by tapering dose prednisone therapy was assessed in six children with systemic lupus erythematosus (SLE) and severe glomerulonephritis.
      
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  sle in children
Systemic lupus erythematosus (SLE) in children is a chronic multi-system disease with wide ranging effects on their quality of life (QOL).
      
Through collaborative research efforts improved understanding of SLE in children and adolescents can be achieved.
      
We present the initial long-term experience of the safety and efficacy of rituximab for treatment of SLE in children.
      
In conclusion, our data support the efficacy of rituximab as adjunctive treatment for SLE in children.
      
A brief review of the literature is presented with a description of the clinical features of SLE in children.
      
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Objectives To search for the therapeutic methods of child patients with systemic lupus erythematosus (SLE) and the effect of cyclophosphamide (CTX) for SLE.Methods The 14 child patients with SLE were divided into two groups: CTX impulsion therapy group (6 cases) and prednisone therapy group (8 cases). The paticnts in CTX group were treated by CTX 20-30mg/kg, divided into two days for intravenous drip. There was a interval of 15 days between the two course of treatment. The prodnisone (1mg/kg) were used too at...

Objectives To search for the therapeutic methods of child patients with systemic lupus erythematosus (SLE) and the effect of cyclophosphamide (CTX) for SLE.Methods The 14 child patients with SLE were divided into two groups: CTX impulsion therapy group (6 cases) and prednisone therapy group (8 cases). The paticnts in CTX group were treated by CTX 20-30mg/kg, divided into two days for intravenous drip. There was a interval of 15 days between the two course of treatment. The prodnisone (1mg/kg) were used too at the same time. The patients in prednisone group were treated by prednisone, 2mg/kg. d, per os, tolal for 8 weeks, then reduced the dose gradually.Results The 5 cases get the obvious effect and 1 casc get the effect in 8 waeks in CTX group, total offective rate is 100%. one case is complete remission, 5 cases have effect and 2 cases are not effect, total effective rate is 75% (P<0.05).Conclusion CTX (intravenous drip) add the small dose of prednisone (per os) is the best therapeutic method for SLE.

研究目的探讨儿童系统性红斑狼疮(SLE)的治疗方法及环磷酰胺(CTX)的疗效。治疗方法SLE患者共14例,CTX冲击治疗组6例,CTX每疗程(20~30)mg/kg,分2d静滴,疗程间隔15d,同时加用强的松1mg/kg。强的松治疗组8例,强的松2mg/(kg·d),连服8周后渐减量维持。结果CTX冲击治疗组8周内显效5例,有效1例,总有效率为100%。强的松治疗组仅1例完全缓解,5例有效,2例无效,总有效率为75%(P<0.05)。结论静滴CTX加小剂量强的松口服是治疗SLE的最佳方法。

Todeterminethepresenceofantigangliosideantibodies(AGA)inchildrenwithneu-ropsychiatriclupuserythematosus(NPLE)anditsassociationwithclinicalcourse,weexamined71serumsamplesand8CSFsamplesfrom47childrenwithsystemiclupuserythematosus(SLE),a-mongwhom13caseswereclinicalydiagnosedasNPLE.SignificantcorrelationwasfoundbetweenAGAincerebrospinalfluid(CSF)andNPLE.CSFspecimensofalthe5patientswithNPLEwerepositiveforIgG-AGAand4ofthemhadpositiveIgM-AGA.Alongitudinalstudyof2casesshowedthatAGAvariedwithclinicalcourses.NosignificantdiferencesinserumAGAwereseenbetweenpatientswithNPLEandthosewithoutNPLE.ThepresentstudysuggeststhatAGAmaybeoneofthemarkersforthediagnosisofNPLEinchildren.Thisresultalsosupportsthehypothesisthatin-trathecalantibodyproductionplaysanimportantroleinimmunopathologicprocessofNPLE....

Todeterminethepresenceofantigangliosideantibodies(AGA)inchildrenwithneu-ropsychiatriclupuserythematosus(NPLE)anditsassociationwithclinicalcourse,weexamined71serumsamplesand8CSFsamplesfrom47childrenwithsystemiclupuserythematosus(SLE),a-mongwhom13caseswereclinicalydiagnosedasNPLE.SignificantcorrelationwasfoundbetweenAGAincerebrospinalfluid(CSF)andNPLE.CSFspecimensofalthe5patientswithNPLEwerepositiveforIgG-AGAand4ofthemhadpositiveIgM-AGA.Alongitudinalstudyof2casesshowedthatAGAvariedwithclinicalcourses.NosignificantdiferencesinserumAGAwereseenbetweenpatientswithNPLEandthosewithoutNPLE.ThepresentstudysuggeststhatAGAmaybeoneofthemarkersforthediagnosisofNPLEinchildren.Thisresultalsosupportsthehypothesisthatin-trathecalantibodyproductionplaysanimportantroleinimmunopathologicprocessofNPLE.

为了解儿童系统性红斑狼疮(SLE)及狼疮脑病(NPLE)时抗神经节甙抗体(AGA)的存在及血清或脑脊液中AGA的临床相关性。采用酶标记免疫测定法检测了47例SLE患儿(其中13例临床诊断为NPLE)的71份血清标本、8份脑脊液标本中的AGA水平。结果脑脊液中的AGA与NPLE有明显相关性,5例NPLE脑脊液中IgG-AGA阳性、4例IgM-AGA阳性。2例的纵向观察显示脑脊液中的AGA变化与临床病程相关。提示AGA有可能作为儿童NPLE诊断的重要指标之一。

Thoughmany patients of acutehemorrhagicnerotizing pancreatitis (AHNP)can be curedafter the active managements, the necroticmass or pancreaticpseudocystsarefound in about20%of the patientswhich needfurthertreatments.Our experience shows that operationat the early stagemakes many absorbable necroticmasses which shouldnotbe infected becomein -frcted severely the incidence of necrotic masses in non-operativegroup are higher than thatin op-erative group;butthe necrotic...

Thoughmany patients of acutehemorrhagicnerotizing pancreatitis (AHNP)can be curedafter the active managements, the necroticmass or pancreaticpseudocystsarefound in about20%of the patientswhich needfurthertreatments.Our experience shows that operationat the early stagemakes many absorbable necroticmasses which shouldnotbe infected becomein -frcted severely the incidence of necrotic masses in non-operativegroup are higher than thatin op-erative group;butthe necrotic masses did not need the operative treatmentsandthey are ab-sorbable in most of the patients;the non-complicated necroticmasses should not be removed promptly since the operationwill bemore safe as the disease prolongs should not be removed promptly since the operationwill bemore safe as the disease prolongs its course our data shows that 82% of the pancreatic pseudocysts formed after the AHNPcanbe absorbed.

小儿狼疮脑病脑脊液改变佟素华,吴凤歧,何晓琥,邓文碧狼疮脑病是儿童系统性红斑狼疮(SLE)常见的严重并发症,有关其脑脊液变化的文献报道不多。为提高对本病脑脊液变化特点的认识,以助早期诊断,我们对20例患儿脑脊液检查结果进行了总结分析,报告如下。临床资...

 
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