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| | The authors used the method of neurobiochemistry to observe the change of β-EP, 5-HT contents in cerebrospinal fluid of 11 cases of prolapsed lumber intervertabral disc patients before and after finger pressing massage. The results showed that at the moment of pain relieved after the therapy, β-EP in cerebrospinal fluid was obviously increased, averagely 40% higher (p<0.05) than that before the therapy. But the changes of 5-HT were irregular. The authors supposed that effect of pain relieving may be due to ... | | 本文运用神经生物化学方法观察测试11例腰椎间盘突出症患者指压推拿前后CSF中β-EP、5-HT的含量变化,结果发现当推拿后腰痛缓解的即刻,CSF中β-EP有明显的升高,较推拿前平均增加40%(P<0.05);但5-HT的升降变化不一(P>0.05),从而推测推拿镇痛的效应环节可能在于有选择性地激活了机体内源性镇痛系统,促进β-EP的释放增加。 | | 文摘来源 | | Observations have been made on two | | 为了解推拿的镇痛作用与致痛物质的关系,分组进行了观察。第一组推拿前后9例急性软组织损伤病人血浆中儿茶酚胺(CA)的变化。第二组推拿前后34例腰椎间盘突出症尿中儿茶酚胺(CA)和它的代谢产物含量变化。结果表明,推拿后血浆中NA含量下降非常显著,DA含量显著下降。推拿后尿中CA,DA,VMA含量均明升高。说明体液中CA与推拿作用密切相关。CA含量在血浆中下降越显著,在尿中升高越显著,临床疗效越好。提示:在推拿过程中,体液内儿茶酚胺是参与调整镇痛的主要物质之一。 | | 文摘来源 | | Tn order to approach the machenisrn of massage analgesia, the article observed the changes of (3-END and released monoamine-subtstance in rabbits' PAG perfusion liquid. The results showed that (3-END increased, contents of NE^DA and DOPAC decreased as analgesia by mild massage therapy; the contents of NE^DA and DOPSAC decreasde significanly, content of J3-END decreased as analgesia by heavy massage therapy, both massage therpies could raise rabbits' pain threshold. Both mild and heavy massage therapies coul... | | 为了探讨推拿镇痛的作用机理,本文采用推挽灌流法直接动态观察了清醒家兔PAG灌流液中β-END及单胺类物质的释放变化,并设立轻、重手法及对照组。结果表明推拿轻手法镇痛时,PAG灌流液中β-END含量升高,NE、DA、及其代谢产物DOPAC含量均降低;重手法镇痛时,NE、DA及DOPAC含量均明显下降,β-END含量亦有所下降,两手法皆能提高家兔痛阈。中央灰质在灌流心得安后,两手法皆不能提高痛阈。由此提示推拿镇痛途径之一是通过降低PAG中的DA而起作用,β受体亦参与此作用,且轻重手法推拿镇痛机制存在差异。 | | 文摘来源 | |   |
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