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慢性重型乙型病毒性肝炎
相关语句
  patients with severe chronic hepatitis b
     Observation on Effects of Foscarnet Sodium Treating Patients with Severe Chronic Hepatitis B
     膦甲酸钠治疗慢性重型乙型病毒性肝炎疗效观察
短句来源
  “慢性重型乙型病毒性肝炎”译为未确定词的双语例句
     Clinical analysis of 50 cases of chronic fulminating virus hepatitis B complicated with infection
     慢性重型乙型病毒性肝炎合并感染50例临床分析
短句来源
     [Results] (1) The values of MELD in all patients were no less than 20. They were 31.89±1.07 in cirrhosis group (n=46) and 34.03±0.81 in chronic hepatitis group (n=118)respectively. The value of MELD in cirrhosis group had no significant difference from that in chronic hepatitis group (P >0.05).
     其中肝硬化组(46例)的MELD值为31.89±1.07,慢性肝炎组(118例)为34.03±0.81,肝硬化组与慢性肝炎组间MELD分值比较,P>0.05,无统计学差异,患者起病时有无肝硬化的基础,可能对慢性重型乙型病毒性肝炎患者的短期预后影响不大。
短句来源
     The patients' onset of chronic liver failure based on cirrhosis might have no important effect on the short-term prognosis. (2) The death rates were 42.4% (28/66), 73.2%(52/71), and 96.2%(26/27) in the patients with 20≤MELD<30, 30≤MELD<40, and MELD≥40, respectively. The higher the MELD value, the higher the death rate.
     ②慢性重型乙型病毒性肝炎患者3个月内的病死率在20≤MELD<30为42.4%(28/66),30≤MELD<40为73.2%(52/71),MELD≥40为96.2%(26/27),MELD分值越高,病死率越高。
短句来源
     Evaluation of the therapeutic effect of thymopentin in the treatment of chronic severe viral hepatitis B
     胸腺五肽治疗慢性重型乙型病毒性肝炎的疗效评价
短句来源
     Value of MELD to Assess the Short-term Prognosis of Patients with Chronic Liver Failure
     MELD评分对慢性重型乙型病毒性肝炎患者短期预后评价的价值
短句来源
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  相似匹配句对
     New Management of Chronic Viral Hepatitis B
     慢性病毒性肝炎治疗新方法
短句来源
     Evaluation of the therapeutic effect of thymopentin in the treatment of chronic severe viral hepatitis B
     胸腺五肽治疗慢性病毒性肝炎的疗效评价
短句来源
     Observation on Effects of Foscarnet Sodium Treating Patients with Severe Chronic Hepatitis B
     膦甲酸钠治疗慢性病毒性肝炎疗效观察
短句来源
     Clinical analysis of 50 cases of chronic fulminating virus hepatitis B complicated with infection
     慢性病毒性肝炎合并感染50例临床分析
短句来源
     Objective:To evaluate the efficacy and safety of Lamivudine in the treatment of chronic severe hepatitis due to hepatitis B virus (HBV).
     目的 :探讨拉米夫定治疗慢性病毒性肝炎的疗效和安全性。
短句来源
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Objective In order to investigate the status of HBV in severe chronic hepatitis B. Methods The preS 1/S2 gene was amplified from the sera of three patients with severe chronic hepatitis B by half nested PCR. The PCR products were cloned into M 13mp18, M13mp19 vector and 10 clones were randomly selected for each person and sequenced with standard metheds. A total of 30 clones were sequenced and analyzed by DNA homology comparison and calibration of genetic distance. Results Two subtypes of HBV were detected in...

Objective In order to investigate the status of HBV in severe chronic hepatitis B. Methods The preS 1/S2 gene was amplified from the sera of three patients with severe chronic hepatitis B by half nested PCR. The PCR products were cloned into M 13mp18, M13mp19 vector and 10 clones were randomly selected for each person and sequenced with standard metheds. A total of 30 clones were sequenced and analyzed by DNA homology comparison and calibration of genetic distance. Results Two subtypes of HBV were detected in three patients but the coexistence of quasispecies and dominant clones in those patients. Abnormally high immune response region might exist in dominant clones .Conclusion The coexistence of quasispecies and dominant clones is the major characteristic in severe chronic hepatitis B.

目的 了解慢性重型乙型病毒性肝炎患者体内HBV的状况。方法 选3例慢性重型乙型病毒性肝炎患者,以HBV前S基因为研究区域,采用半套式PCR法,从3例患者血清中扩增出HBV前S基因,并分别将其克隆于噬菌体M13mp18、M13mp19载体中,每例患者随机筛选10个阳性克隆,进行序列分析及遗传距离分析。结果 此3例患者存在着“相似株”与“优势株”的混杂及HBV adr与HPB adrwl两种亚型的混合感染。优势株内可能存在引起机体免疫性增高的区域。结论HBV“相似株”与“优势株”的混杂可能是慢性重型乙型肝炎的一个特点。

Objective To investigate the status of in vivo HBV in chronic severe hepatitis B. Methods The preS1/S2 gene was amplified from the sera of four patients with chronic severe hepatitis B by half nested PCR. The PCR products were cloned into M13mp18, M13mp19 vector, and 10 clones were randomly selected and sequenced with standard methods for each person. A total of 30 clones were sequeuced and analyzed by DNA homology comparison and calibration of genetic distance. Result The mixed infection of two subtypes of...

Objective To investigate the status of in vivo HBV in chronic severe hepatitis B. Methods The preS1/S2 gene was amplified from the sera of four patients with chronic severe hepatitis B by half nested PCR. The PCR products were cloned into M13mp18, M13mp19 vector, and 10 clones were randomly selected and sequenced with standard methods for each person. A total of 30 clones were sequeuced and analyzed by DNA homology comparison and calibration of genetic distance. Result The mixed infection of two subtypes of HBV was detected in three patients also the coexistence of quasispecies and dominant clones. Dominant clones may exist in abnormally high immune response region. Conclusion The coexistence of quasispecies and dominant clones was the major characteristic in chronic severe hepatitis B.

目的了解慢性重型乙型病毒性肝炎患者体内HBV的状况。方法选3例慢性重型乙型病毒性肝炎患者,以HBV前S基因为研究区域,采用半巢式PCR法,从此3例患者中血清中扩增出HBV前S基因,并分别将其克隆于噬菌体M13mp18、M13mp19载体中,每例患者随机筛选10个阳性克隆,进行序列分析及遗传距离分析。结果此3例病人存在着“相似株”与“优势株”的混杂及HBVadr与HPBadrwl两种亚型的混合感染。优势株内可能存在引起机体免疫性增高的区域。结论 HBV“相似株”与“优势株”的混杂可能为慢性重型乙型肝炎的一个特点。

To study the serum level of sIL-2R and the relationships between sIL-2R and liver injury of patients with acute and chronic hepatitis B. The level of sIL-2R was measured by a monoclonal and polyclonal antibody ELISA.The levels of sIL-2R of patients with acute and chronic hepatitis B were significantly higher than those in healthy subjects. The sIL-2R levels in the patients with hepatitis B correlated well with ALT, AST, PTA and ChE. The serum levels of sIL-2R in patients with acute and chronic hepatitis B are...

To study the serum level of sIL-2R and the relationships between sIL-2R and liver injury of patients with acute and chronic hepatitis B. The level of sIL-2R was measured by a monoclonal and polyclonal antibody ELISA.The levels of sIL-2R of patients with acute and chronic hepatitis B were significantly higher than those in healthy subjects. The sIL-2R levels in the patients with hepatitis B correlated well with ALT, AST, PTA and ChE. The serum levels of sIL-2R in patients with acute and chronic hepatitis B are increased obviously and reflecting the immune function, degree of liver cells damage and inflammation of the patients.

检测乙型病毒性肝炎患者血清可溶性白细胞介素 2受体 (sIL - 2R)的水平及其与血清丙氨酸氨基转移酶 (ALT)、天冬氨酸氨基转移酶 (AST)、凝血酶原活动度 (PTA)、胆碱酯酶 (ChE)及乙肝病毒复制标志物之间的关系。采用酶联免疫法 (ELISA)检测 77例乙型病毒性肝炎患者和 2 0例正常人血清sIL - 2R含量。乙型病毒性肝炎患者血清sIL - 2R水平显著高于正常人 ,并且其升高与ALT、AST、PTA、ChE相关 ,与乙肝病毒的存在和复制与否无关。急性、慢性、重型乙型病毒性肝炎及乙肝后肝硬化患者血清sIL - 2R水平在一定程度上反映了肝细胞损伤及炎症程度

 
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