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肝纤维化诊断     
相关语句
  liver fibrosis diagnosis
     Significance of Serum Laboratory Markers in Liver Fibrosis Diagnosis
     血清标志物在肝纤维化诊断及病情进展监测中的意义
短句来源
  diagnosis of hepatic fibrosis
     Significance of serum procollagen type Ⅲ(PCⅢ) in diagnosis of hepatic fibrosis
     血清Ⅲ型前胶原(PCⅢ)在肝纤维化诊断中的意义
短句来源
     Serum Hyoluronic Acid(HA) and Precollagen Ⅲ(PCⅢ) Level of Hepatopath in Diagnosis of Hepatic Fibrosis
     肝病患者血清HA、PCⅢ水平在肝纤维化诊断中的意义
短句来源
     The Significance of Type Ⅲ Procollagen and Laminin in Diagnosis of Hepatic Fibrosis
     Ⅲ型前胶原与层粘连蛋白在肝纤维化诊断中的意义
短句来源
     EVALUATION OF DETERMINATION OF SERUM COLLAGEN(TYPE Ⅳ)IN DIAGNOSIS OF HEPATIC FIBROSIS
     血清Ⅳ型胶原测定在肝纤维化诊断中的价值探讨
短句来源
     Objectives To detect the expressions of serum transforming growth factorβ(TGFβ1) and tissue inhibitor of metalloproteinase 1(TIMP-1)in patients with chronic hepatitis B(CHB)in different phases of their liver fibrosis and to investigate the effects of TGFβ1 and TIMP-1 on the diagnosis of hepatic fibrosis and the relationship between them.
     目的通过检测慢性乙型肝炎患者血清TGFβ1和TIMP-1在肝纤维化不同阶段的表达情况,探讨TGFβ1和TIMP-1在肝纤维化诊断中的作用及相互关系。
短句来源
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  liver fibrosis diagnostic
     Objective To evaluate usage value of serum liver fibrosis diagnostic index of HA、LN、PⅢ P and Ⅳ-C in clinic practice.
     目的 评价血清透明质酸(HA)、层粘连蛋白(LN)、Ⅲ型前胶原肽(PⅢP)和Ⅳ型胶原(Ⅳ-C)在肝纤维化诊断中的临床应用价值。
短句来源
  diagnosing hepatic fibrosis
     VALUE OF DETERMINATION OF BOTH HYALURONIC ACID AND LAMININ IN SERUM IN DIAGNOSING HEPATIC FIBROSIS
     血清透明质酸和层粘连蛋白检测在肝纤维化诊断中的价值
短句来源
     APPLICATION OF DETERMINATION OF SERUM LEVELS OF COLLAGEN TYPEⅣ,PROCOLLAGEN TYPE Ⅲ,HYALURONIC ACID AND LAMININ IN DIAGNOSING HEPATIC FIBROSIS
     血清HALNCPⅢ和Ⅳ-C测定在肝纤维化诊断中的应用
短句来源
     Objective To explore the significance of variations of Hyaluronic acid (HA) and Laminin(LN) contents in serum in diagnosing hepatic fibrosis.
     目的 探讨血清中透明质酸( H A) 和层粘连蛋白( L N) 含量的变化在肝纤维化诊断中的意义。
短句来源
     The results of the serum hepatic fibrosis-related markers in disease group were analyzed and compared with the findings of hepatic histology and the serum hepatic fibrosis-related markers in control group in order to find the superior sensitivity(Se) and specificity(Spe) indices diagnosing hepatic fibrosis.
     将病例组血清学指标结果与肝活检病理结果及正常对照血清学指标结果进行对比分析,找出灵敏度(Se)、特异度(Spe)高的肝纤维化诊断指标。
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      diagnosis of hepatic fibrosis
    Alkaline phosphatase of the fibloblasts and its clinical significance in the diagnosis of hepatic fibrosis
          


    AIM To study the serum diagnostic value of phosphonate esteraes for liver fibrosis.METHODS Liver fibrosis was induced in rats with CCl4.Serum phosphonate esterase(PE)was measured by flurometry at4,8,12,14 weeks after the first injection of CC14.Serum type Ⅲ procollagen(PCⅢ)and hyaluronic acid(HA)weredetected using radioimmunoassay.RESULTS The serum levels of PE were 168.6 ±40.0(4wk),212.9±32.1(8wk),271.5±40.6(12wk)and 243.1±83.1IU/L(14wk)respectively,which were significantly higher than that in normal animals(91.0±25.0...

    AIM To study the serum diagnostic value of phosphonate esteraes for liver fibrosis.METHODS Liver fibrosis was induced in rats with CCl4.Serum phosphonate esterase(PE)was measured by flurometry at4,8,12,14 weeks after the first injection of CC14.Serum type Ⅲ procollagen(PCⅢ)and hyaluronic acid(HA)weredetected using radioimmunoassay.RESULTS The serum levels of PE were 168.6 ±40.0(4wk),212.9±32.1(8wk),271.5±40.6(12wk)and 243.1±83.1IU/L(14wk)respectively,which were significantly higher than that in normal animals(91.0±25.0 IU/L).The changes ofserum PE had a positive relation with serum PCⅢ and HA.CONCLUSION Serum PE is strongly related to hepatic fibrosis.It can be used as a serum marker in liver fibrogencsis.

    目的:探讨肝纤维化大鼠血清有机磷酸酯酶的变化。方法:用四氯化碳诱导大鼠产生肝纤维化,分别于第4,8,12,14周用荧光分光法测定血清有机膦酸酯酶(PE)水平,并与血清PCⅢ,HA进行比较。结果:于实验第4,8,12,14周,大鼠血清PE水平分别为168.6±40.0,212.9±32.1,271.5±40.6与243.1±83.1IU/L,均明显高于正常大鼠(91.0±25.0IU/L)。与血清PCⅢ及HA呈显著正相关。结论:肝纤维化时血清PE明显升高,且与肝纤维化程度呈正相关,可作为肝纤维化诊断的血清学指标之一。

    The serum content of

    采用放免法检测了147例慢性肝病(CLD)患者血清Ⅲ型前胶原(PCⅢ)的含量变化,其中慢性迁延性肝炎35例,慢性活动性肝炎24例,肝炎后肝硬化48例,重症肝炎及肝癌各20例;另外,也检测了50名健康人作为对照,结果表明,健康人血清PCⅢ含量为87.5±10.4μg/L;各种CLD组者则明显高于健康人水平,其中,肝硬化组增加更见显著,而且与其他CLD组两两比较亦有显著差异。各种CLD的PCⅢ与某些肝功能指标之间无明显相关,提示在CLD病中检测血清PCⅢ对肝纤维化的诊断应有其一定意义。

    612 patients with chronic liver diseases,including chronic persisting hepatitis,chronic active hepatitis, posthepatitic cirrhosis, schistosomiasis japonica were detected by the methods of serodiagnosis which are ADA, CG, β2-M, NAG, GST, HYP, PⅢP, HA, LN, TNF-α and sIL-2R,The results of serological test were indicated by positive rate(>X+2SD) and same as the results of hepatic histological examination. The order of degree of seriousness of hepatic fibrosis are early stage of schistosomiasis japonica and chronic...

    612 patients with chronic liver diseases,including chronic persisting hepatitis,chronic active hepatitis, posthepatitic cirrhosis, schistosomiasis japonica were detected by the methods of serodiagnosis which are ADA, CG, β2-M, NAG, GST, HYP, PⅢP, HA, LN, TNF-α and sIL-2R,The results of serological test were indicated by positive rate(>X+2SD) and same as the results of hepatic histological examination. The order of degree of seriousness of hepatic fibrosis are early stage of schistosomiasis japonica and chronic persisting hepatitis< advanced stage of schistosomiasis japonica

    对慢迁肝、慢活肝、肝炎后肝硬化、日本血吸虫病早期和晚期患者共612例(其中157例经肝活检确诊)进行血清ADA、CG、β_2-M、NAG、GST、HyP、PIP、HA、LN、TNF-α、sIL-2R等11项指标的检测.检测结果用阳性(>(?)+2SD)率表示,大致与肝组织学检查结果相似,肝纤维化程度早血、迁肝<晚血<慢活肝<肝炎后肝硬化,而肝脏炎症、坏死则以慢活肝为重.我们认为肝纤维化的诊断应综合考虑.本文从反映慢性肝受损指标、细胞外间质代谢指标及细胞因子网络失调指标3方面,初步提出肝纤维化血清学诊断指标谱,供讨论。

     
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