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hev感染
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  hev infection
     Case fatality rates were 73.4%(69/94)in patients with HBV plus HEV superinfection and 68.6% (72/105) in patients with HEV plus other hepatitis virus superinfection, which were much higher than those in patients with HBV infection alone (P< 0.01) or HEV infection alone (P < 0.05) .
     HBV重叠HEV感染者病死率为73.4%(69/94),HEV重叠其他肝炎病毒感染者的病死率为68.6%(72/105),均比单一HBV或单一HEV感染者高(P<0.01和P<0.05)。
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     Conclusion AFP level in HCC is higher than 400ng/ml, and mostly related to the infection of HBV and HAV, while in BLD pationts the AFP level in the range of 101 - 400ng/ml,and mainly related to HBV, HAV and HEV infection.
     结论:本地区HCC患者AFP水平多≥400ng/ml,主要与HBV及HAV感染有关; BLD患者AFP水平范围多为101-400ng/ml,主要为HBV、HAV和HEV感染
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     HEV/HBV and HEV/HAV superinfection were more often as compared with HEV infection alone(P<0.01). HEV/HBV superinfection was the greater part of the 42 cases (71.42%).
     HEV与HBV、HAV双重感染高于单纯HEV感染(P<0.05),其中以HBV与HEV双重感染最多见,占HEV感染的71.42%。
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     But in patients co-infectedwith HEV and HAV,the detection rates of anti-HEV-IgG were ata low level,they were 23.9% and 12.5% in acute and early convalescent phase respectively,there was significant dif-ference in HEV infection and HEV and HAV co-infection(P<0.01 ).
     单纯HEV感染中,抗-HEV-IgG从急性期急剧上升至95%后,恢复期仍维持在81.8%的较高水平,而在HEV+HAV合并感染中,急性期和恢复期抗-HEV-IgG仅分别为23.9%和12.5%,和单纯HEV感染有显著性差异(P<0.01)。
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     Conclusion The age of HEV/HAV superinfection was decreased when compared with that of HEV infection alone (P<0.05).
     结论HAV与HEV双重感染比单纯HEV感染发病年龄下移(P<0.05),但病情无加重。
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  “hev感染”译为未确定词的双语例句
     Methods Serum levels of aspartate aminotransferase (AST), alannine aminotransferase (ALT) total bilirubin (TBIL), prothrombin time (PT), total protein (TP), albumin(ALB), albumin/globulin (A/G), and HBV-DNA, and the clinical characteristicof the patients with simple HBV infection were compared with those of patients with HBV and HEV superinfection.
     方法对单纯HBV感染者与HBV重叠HEV感染者血清天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、总胆红素(TBIL)、凝血酶原时间(PT)、总蛋白(TP)、白蛋白(ALB)、白蛋白/球蛋白(A/G)、HBV-DNA及临床特征进行对照分析。
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     the infction rate of hepatitis B combinedwith NAV HCV HDV and HEV were 8.03%,17.09%,6. 99 % and 0. 77 % respectively.
     其中合并HAV、HCV、HDV和HEV感染的感染率分别为8.03%、17.09%、6.99%和0.77%。
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     The positive rates of serum AFP in HBV patients was 35.3%, superinfected with HAV or with HEV was 62.8%, and with HCV was 27.3%.
     在肝炎病因分类中单纯HBV感染或HBV基础上又有HAV /HEV感染者AFP阳性率较高 ,为 35 .3%和 6 2 .8%,HBV与HCV双重感染者为 2 7.3%。
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     the rates increased steadily with age, it was 7.2% in persons<5 years old, at ages 5 to 9, the rate increases to 9.0%, reaching two peaks of 29.3% and 33.2% in ages 30~39 and more than 50. The peak rates of anti-HEV were earlier 10 years in Guangxi than those in other areas.
     HEV感染率随年龄增长而上升,生命早期即有高度的HEV感染,1~4岁为7.2 %,5~9岁开始上升(9.0 %),10岁以后感染率成倍增加(14.8 %~29.7 %) ,有两个小峰分别在30~39岁(29.3 %)和50岁以上(33.3 %)。
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     Result A total of 167 hepatitis E cases were all sporadic without seasonal variation,their age distribution was mostly in the adults beyond 40 years old with an average of 42.12±14.06 years,and the ratio of male to female was 2.71∶1.The 79 cases of them(47.31%) were HBV/HEV superinfection,and the other 88 cases(52.69%) were the simple hepatitis E.
     结果167例戊型肝炎均为散发型,发病无明显季节性,以40岁以上成人发病为主,平均年龄为42.12±14.06岁,男女比例为2.71∶1。 其中,慢性HBV感染重叠HEV感染(简称乙戊肝)79例(47.31%),单纯戊型肝炎88例(52.69%)。
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  相似匹配句对
     infection;
     感染 ;
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     ACP and MDA of patients with periodontitis infected with E.
     感染 E.
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     Conclusion These results indicated that of intrauterine infection with HEV does exist.
     结论HEV存在宫内感染
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     Investigation of Hepatitis E in 369 Cases of Viral Hepatitis
     病毒性肝炎患者中HEV感染的调查
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  hev infection
Thirty-nine of the 53 patients (73.3%) and none of the control group were positive for HEV infection, according to results shown by ELISA.
      
Further studies are needed in the other regions to determine the true prevalence of HEV infection in Turkey.
      
Here we report on a patient, who obviously acquired his HEV infection in Germany.
      
Two variants of HEV were detected, and the first human cases of HEV infection in this region were demonstrated.
      
Although usually asymptomatic, HEV infection can cause fulminant hepatitis.
      
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An experimental model of hepatitis E was es- tablished in rhesus monkeys (Macaca mulatta). First-passage animals were inoculated with two different stool samples obtained from patients with hepatitis E which originated from Xinjiang and Shenyan, respectively. Three of four monkeys were infected. 27~34nm diameter viruslike particles were found in feces of infected animals by immune electron microscopy (IEM). Liver biopsy of the three monkeys showed that histopath ologic changes of actue-phase hepatitis. Secondpassage...

An experimental model of hepatitis E was es- tablished in rhesus monkeys (Macaca mulatta). First-passage animals were inoculated with two different stool samples obtained from patients with hepatitis E which originated from Xinjiang and Shenyan, respectively. Three of four monkeys were infected. 27~34nm diameter viruslike particles were found in feces of infected animals by immune electron microscopy (IEM). Liver biopsy of the three monkeys showed that histopath ologic changes of actue-phase hepatitis. Secondpassage animals were inoculated with HEY in both stool and liver suspensions from a first-passage monkey (M-16), including one animal inoculated with liver suspension. All of them were infected.

选用1~3岁龄的猕猴(maca mulatta)15只(其中有2只对照)进行了戊型肝炎病毒(Hepatitis E virus简称HEV)的感染实验。第1代感染两批动物:第1批感染4只,3只发病;第2批感染4只,全部发病。后用第2批感染猴的粪便及肝脏悬液作为第1代,进行第2代感染。第2代感染4只猴,也全部发病,用肝悬液传代的1只猴也发病。感染后发病的猴血清丙氨酸转氨酶(ALT)水平均有不同程度的上升,一般高于正常值3~6倍,最高可10倍左右。肝活检可见肝细胞炎症和坏死。猴的粪便标本用免疫电镜(IEM)检测可见直径为27~34nm的病毒颗粒。

The fragment genome of hepatitis E viruses were cloned as cDNAs, two from an epidemic outbseak of hepatitis E in the East Xinjiang of China(named HEV China XT-179 strain). cDNA sequence comparison was performed in the. 3'-terminal region, which showed 94.3% homology at nucleotide level and 99.6% homology at the amino acid level, approximally 820 base long between HEV China XT-179 and Myanmar ET1.1 strains. The peptide antigen was synthesed as their same amino acid sequence of immunoreactive epitopes, and also...

The fragment genome of hepatitis E viruses were cloned as cDNAs, two from an epidemic outbseak of hepatitis E in the East Xinjiang of China(named HEV China XT-179 strain). cDNA sequence comparison was performed in the. 3'-terminal region, which showed 94.3% homology at nucleotide level and 99.6% homology at the amino acid level, approximally 820 base long between HEV China XT-179 and Myanmar ET1.1 strains. The peptide antigen was synthesed as their same amino acid sequence of immunoreactive epitopes, and also reacted with 29 sera of patients with hepatitis and 8 sera of normal people from the East Xinjiang of China when compared with that of HEV particle antigen of China XT-179 strain. The results showed that positive reaction with the sera of patients and nagtive reaction with normal sera coincident rate was 92.6% and 100%. These results obviously demonstrates in that recombinant DNA can be used for the development of detection system and vaccine of prevention of HEV infection and identification of virological link of different geographical locations.

本文报道对中国新疆东部一起戊型肝炎(HE)流行中2例HE患者粪便中分离到的HEV中国XT-179株系基因组进行cDNA分子克隆和其免疫原性表位的血清学研究结果。cDNA序列分析表明中国XT-179株与缅甸ET1.1株之间有94.3%的核苷酸和99.6%的氨基酸具有同源性。但也有5.7%的核苷酸区别于其他HEV地理株和散发株,提示在中国流行型HEV可能存在独特的基因型,可将此毒株序列作为鉴别HEV不同毒株的病毒学依据之一。本研究还按上述HEV地理株之间共有的免疫原性表位氨基酸序列合成了多肽抗原,用于检测来自中国XT-179株系流行区的29例HEV感染者和8例正常人血清抗-HEV,与应用HEV中国XT-179株系颗粒抗原相比,两组血清抗-HEV阳性和阴性的符合率分别为92.6%和100%。证实本项研究所克隆的HEV基因组可用于制备HEV重组基因疫苗和免疫诊断制剂。

Hepatitis E virus(HEV) was isolated in human embryomic lung cell inoculated with liver tissue suspension from an HEV-infected rhesus monkey, Slight cytopathic effect(CPE) appeared at the 27th day after 4 blind passages of viruses in cell culturs to at 17th day after 7 passages. Low amounts of 27—34nm virus-like particles(VLPs) in cell cultures were visualized by immunoelectronmicroseopy(IEM). 2 of 3 rhesus monkeys inoculated with 20ml of pool of cell cultures from 4 to 7 passages developed significant elevation...

Hepatitis E virus(HEV) was isolated in human embryomic lung cell inoculated with liver tissue suspension from an HEV-infected rhesus monkey, Slight cytopathic effect(CPE) appeared at the 27th day after 4 blind passages of viruses in cell culturs to at 17th day after 7 passages. Low amounts of 27—34nm virus-like particles(VLPs) in cell cultures were visualized by immunoelectronmicroseopy(IEM). 2 of 3 rhesus monkeys inoculated with 20ml of pool of cell cultures from 4 to 7 passages developed significant elevation of ALT levels and all of those monkeys inoculated with the same cell cultures one year after their recovery developed typical hepatitis. 27—34nm VLPs in their bile juice were found by IEM. It is concluded that those cell culture-adapted viruses may be hepatitis E virus.

本文报告用2BS细胞分离戊型肝炎病毒(HEV)感染成功的猴肝脏标本中的HEV的初步结果,将2BS细胞长成致密单层,接种已知含有HEV的肝悬液,盲传至第4代,发现在第27天细胞出现了轻微的细胞病变(CPE),随着进一步的传代,细胞病变时间逐渐提前。至第7代时,在第17天就可见到CPE,CPE的主要特征是细胞间隙变宽,透明度降低和轻度细胞破坏,无大片细胞溶解和脱落现象。免疫电镜检查在第5代和第6代细胞培养液中见到很少的27—34nm的病毒颗粒。将第4代至第7代的细胞悬液20ml接种了3只恒河猴,有2只猴在24天和26天出现了典型的ALT升高,待这3只猴恢复正常后一年,再次接种以上细胞悬液20ml,3只猴全部发生了ALT升高,并在胆汁中检查到27—34nm的病毒颗粒,我们初步推测2BS适应的这株病毒很可能是戊型肝炎病毒。

 
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