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急性肾损伤的
相关语句
  acute renal injury
     Recently, systemic inflammatory response syndrome (SIRS) induced by cardiopulmonary bypass(CPB)had been considered as an important mechanism in which acute renal injury associated with CPB devoloped.
     目前,人们多认为体外循环(cardiopulmonary bypass;CPB)引起的全身性炎症反应综合征(systemic inflammatory response syndrome;SIRS)是导致CPB相关急性肾损伤的重要因素。
短句来源
     Protective effect of astragalusangelica mixture(黄芪当归合剂) on ischemic acute renal injury in rats
     黄芪当归合剂对大鼠缺血性急性肾损伤的保护研究
短句来源
     Protective Effects on Acute Renal Injury and Regulation of NK Cell's Function by Modified Heparins
     修饰肝素对急性肾损伤的防治及NK细胞功能的调节
短句来源
     (2)The interaction between gentamicin and phospholipids of biological membranes, production of ROM and its induced lipid peroxidation, and increase of ET synthesis and release play an important role in pathogenesis of gentamicin-induced toxic acute renal injury, gentamicin-induced toxic acute renal injury is probably the result of the comprehensive effect of the above mechanisms.
     ②在庆大霉素中毒性急性肾损伤的发病机理中,GM与生物膜磷脂的相互作用,ROM产生与脂质过氧化,ET合成释放增加发挥了重要作用,GM诱导的急性肾损伤可能是以上机理综合作用的结果。
短句来源
     Objective To determine the role of antioxidant vitamins and calcium channel blockers in pr eventing or alleviating acute renal injury in children during extracorporeal sho ck wave lithotripsy (ESWL).
     目的 探讨抗氧化维生素和钙通道阻滞剂对体外冲击波碎石术 (ESWL)所致儿童急性肾损伤的保护作用。
短句来源
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  “急性肾损伤的”译为未确定词的双语例句
     Contrast-enhanced Ultrasound for Evaluation of Acute Renal Trauma: An Experimental Study
     超声造影评价急性肾损伤的实验研究
短句来源
     So this study established mercury chloride as the research object, to explore the effect of glu-tathione and taurine on acute nephrotoxicity caused by mercury, the effect of glutathione and taurine on renal acute oxidative damage caused by mercury, the dose-effect relation of renal cell apoptosis induced by mercury and the effect of glutathione and taurine on renal cell apoptosis induced by mercury, accordingly, to provide farther academic evidences for the molecular biological mechanism of mercuric renal damage.
     为此,本研究以氯化汞为研究对象,从谷胱甘肽(Glutathione,GSH)和牛磺酸(Taurine,Tau)对汞致急性肾损伤的影响,谷胱甘肽和牛磺酸对汞致肾氧化损伤影响,汞致肾细胞凋亡的量效关系,谷胱甘肽和牛磺酸对汞致肾细胞凋亡的影响四方面,初步探讨谷胱甘肽和牛磺酸对元机汞肾损伤影响及其机制。
短句来源
     Objective To observe the effect of millimeter wave irradiation on experimental renal impairment in rabbits.
     目的 研究毫米波辐射对庆大霉素所致家兔急性肾损伤的影响 ,寻求防治药物诱发肾损伤的新方法。
短句来源
     Real time gray-scale ultrasound contrast imaging in diagnosis of acute renal trauma: experimental study
     实时灰阶超声造影诊断急性肾损伤的实验研究
短句来源
     Objective To study the feature of renal damage induced by overtraining and the protective effect of anisodamine on the damage.
     目的研究过度训练致急性肾损伤的特点及山莨菪碱的保护作用。
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  相似匹配句对
     The mechanism of renal failure could be acute nephrocalcinosis.
     损伤的机制可能为急性钙质沉着。
短句来源
     THE CHANGE IN RENAL TISSUE INJURY AFTER ACUTE ISCHEMIC REPERFUSION
     急性缺血再灌流损伤的组织学变化
短句来源
     STUDY ON THE MECHANISM OF ACUTE RENAL ISCHEMIC REPERFUSION INJURY IN RABBITS
     急性缺血再灌流损伤的机理研究
短句来源
     Protective Effect of Anisodamine on the Renal Damage Induced by Overtraining in Rat
     山莨菪碱对过度训练大鼠急性损伤的保护作用
短句来源
     Contrast-enhanced Ultrasound for Evaluation of Acute Renal Trauma: An Experimental Study
     超声造影评价急性损伤的实验研究
短句来源
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  acute renal injury
After acute renal injury, renal expression of several growth factors becomes transiently altered.
      
The data indicate thatCCr is not an accurate indicator of GFR in children who have had acute renal injury.
      
It is reported that urinary annexin V concentration may be an indicator of apoptosis and acute renal injury related to the urinary protein level.
      
Reactive oxygen species (ROS) have been postulated to play a major role in postischemic acute renal injury.
      
Insulin-like growth factor-I increases p21 expression and attenuates cisplatin-induced acute renal injury in rats
      
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male rabbits were divided into three groups and were treated with three energy levels (20KV, 750SW; 14kv,1 500kv; 10kv, 3 000kv) of extracorporeal shock wave (ESW) respectively. The results suggest that acuterenal injury was minimal in the Ⅱ group as compared with the other two groups.The biological effects of ESW on kidney caused an increase of γGT in urine,degeneration and or necrosis of tubular cells in ultrastructure, and intrarenal and perirenal bleeding in histology.The biological effects were renovated...

male rabbits were divided into three groups and were treated with three energy levels (20KV, 750SW; 14kv,1 500kv; 10kv, 3 000kv) of extracorporeal shock wave (ESW) respectively. The results suggest that acuterenal injury was minimal in the Ⅱ group as compared with the other two groups.The biological effects of ESW on kidney caused an increase of γGT in urine,degeneration and or necrosis of tubular cells in ultrastructure, and intrarenal and perirenal bleeding in histology.The biological effects were renovated with absorbtion and or fibrosis in 28 days after ESW. There was a noted relationship between the energy level (generator voltage and shock wave number) and the biological effect on kidney.

雄性家兔45只,分为3组,分别接受三个能量级(20kV,750SW;14kV,1500SW;10kV,3000SW)体外冲击波处理。结果表明,2组动物急性肾损伤程度较其它两组病变轻微。体外冲击波对肾脏的生物学效应表现为尿酶γGT升高;超微结构显示肾小管上皮细胞变性坏死;组织学显示肾内和肾周出血。实验第28天的生物学效应表现为吸收和(或)纤维化修复。体外冲击波能量(包括电压和冲击次数)与其对肾脏生物学效应程度相关。

Cordyceps sinensis(CS)is a potent mitogen for spleen cell.We exami-ned the effect of CS on DNA synthesis in renal tubular cell,The effect of CS on tubu-lar cell expression Of mRNA encoding cell growth regulating protooncogene c-myc wasalso examined. ̄3H-thymidine incorporation in tubular cell was stimulated after the abbit-ion of sera taken from rat fed with CS. Renal tubular cell responded to CS solutionwith a 2.2 fold increase in concentration of 50μg/ml.However,further increament of CSsolution to 75μg/ml induced...

Cordyceps sinensis(CS)is a potent mitogen for spleen cell.We exami-ned the effect of CS on DNA synthesis in renal tubular cell,The effect of CS on tubu-lar cell expression Of mRNA encoding cell growth regulating protooncogene c-myc wasalso examined. ̄3H-thymidine incorporation in tubular cell was stimulated after the abbit-ion of sera taken from rat fed with CS. Renal tubular cell responded to CS solutionwith a 2.2 fold increase in concentration of 50μg/ml.However,further increament of CSsolution to 75μg/ml induced an inhibition of cell proliferation.The mechanism of itsbiphasic effect remained unexplored.CS(5μg/ml)upregulated c-myc mRNA expressionwithin 30 minutes and the effect was substained for 4 hours,which suggested an inter-ference in cell growth by pathways associated with modulation of the c-myc mechanism. It was demonstrated previously that the adminstration of mitogen for renal tubularcell,like EGF and TGF-α,accelerated the regencration of tubular cell after acute tubu-lar injury.To investigate whether there exists an associated responsiveness in CS. westudied renal function and recovery of tubular damage in acute gentamicin nephrotoxicmodel of rat,The use of CS prompted an earlier recovery from acute tubular injury ascompard with control.Thus,both in vitro and in vivo studies proved that CS is amitogen for tubular cell and it may be a herb of value in treatment of acute renalfailure.

本研究证明冬虫夏草对体外培养的大鼠肾小管上皮细胞增殖具有明显促进作用,其增殖效应的机制可能与诱导肾小管细胞持续高水平地表达c-myc原癌基因mRNA有关,鉴于急性肾衰治疗的中心环节正在于如何促进损伤、坏死的肾小管细胞再生、修复,因而推测虫草的上述作用可能对于急性肾衰治疗有益,采用虫草治疗庆大霉素诱发的大鼠急性肾损伤,确实具有良好的效果。

n

随机将174只大鼠分为Ⅰ、Ⅱ、Ⅲ组,每组58只动物。Ⅰ组:用等渗盐水灌胃;Ⅱ组:用毒蕈匀浆液灌胃;Ⅲ组:毒蕈匀浆液灌胃同时腹腔注射山莨菪碱(654-2)注射液,观察肾脏生化和形态学改变。Ⅱ组灌胃后6h肾皮质自由基有关指标出现明显变化,肾近曲和远曲小管出现超微结构病变,24h后出现光镜下病变,尿钠、钾排泄增加,尿渗透压降低。Ⅲ组灌胃后12h肾皮质匀浆自由基有关指标出现异常变化,肾近曲和远曲小管出现超微结构病变,晚于Ⅱ组出现;48h后出现光镜下病变,尿钠、尿钾排泄增加,尿渗透压降低。说明65个2对毒蕈所致大鼠急性肾损伤有一定的保护作用。

 
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