To study the preventive effect of aspirin (ASA) on diabetic microangiopathy,we assayed platelet number and the level of a-granule membrane protein 140 (GMP-140)on platelet surface of 95 cases with NIDDM who had administered ASA and of 46 normal controls.
Objective It is to observe the influence, clinical curative effect and safety of low-dose Aspirin combined with Yinxingdamo injection on platelet number, volume and function of the patients with acute cerebral infarction.
The improvements of hemorheology, the decrease of the thick in endometrium and the content of Fibrinogen (FIB), the shorting of PT and APTT, the increase of the Ca~2+ level of blood serum and the number of platelet in treatment group are significant difference between pretreatment and post-treatment (P<0.05), the difference is significant compared with control group (P< 0.05).
DB403 (Pro-TPO) was administrated peritoneally to Babl/c mice and got the number of platelet increased by 84. 2% (self control) and 99. 7% (saline control).
Out of other 6 IMF patients without JAK2V617F point mutation only 1 patient had thrombosis, and lower counts of platelets in perepheral blood and megakaryocytes in bone marrow.
It is concluded that majority of IMF patients with positive JAK2V617F point mutation have typical clinical and hematologic features, higher incidence of thrombosis, and higher counts of platelets in peripheral blood and megakaryocytes in bone marrow.
Thrombelastography variables(R,K,ANG,MA) and PT,APTT,TT,platelet count were measured before fluid infusion(T_1),5min after operation beginning(T_1),30 min after operation(T_3) and 6 h after operation(T_4).
Blood volume of tissue samples was measured by intravenous injection of 125I-albumin and the platelet number by labelling of autologous platelets with 51Cr.
Both the untreated and treated copolymers induced only slight variations of platelet number, but determined the activated partial thromboplastin time (APTT) increase, due to factor XI reduction.
Moreover, the number of platelet, monocyte, red blood cells, haemoglobin, packed cell volume, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration had no significant change (P>amp;gt;0.05).
Newly developed particle-counting methods that employ light scattering (LS) can be used to quantify changes in the number of platelet aggregates of different sizes after administration of an aggregating stimulus.
In vitro adsorption of plasma protein on five polymer surfaces was studied by elec-trophoresis. Adhesion of platelet on these polymer surfaces was observed by scanning electron microscopy. Experimental results indicate that concentration of adsorbed albumin on hydrophobic polymer surfaces is higher, number of adhered platelets is less and these polymer are non-thrombogenic materials.
There was a significant reduction in the platelet count on the next day of mating in pregnant cat compared with unpregnant (P<0.01). After the embryo recovery from the oviduct or uterus the platelet count retruned to the normal levels within 7 days. Thrombocytopenia did occur on day 2 of embryo transfer to pseudopregnant recipients. So the decrease in the platelet count was dependent upon the presence of fertilized eggs in the reproductive tract. The platelet count is designed to determine whether the chang...
The toxicities of total Glucosides of Paeony(TGP)were studied. The iv and ip LD50 of single dose of TGP were found to be 159 and 230mg/kg respectively. Single dose of TGP>2500mg/kg ( ig ) gave no any toxic symptom nor death. In long-term toxicity test, 50, 1000 and 2000mg/kg·d-1 ig on 30~90 consecutive days to rats and 280 and 560mg/kg·d-1 ig on 90 consecutive days to dogs respectively, revealed no significant toxicity in general physical signs, body weight, appearance. behavious, routine urine test, routin...
血小板数目
platelet number
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