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人膀胱肿瘤
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  human bladder carcinoma
     Distribution and significance of oncogene C-erbB-l/EGFR on human bladder carcinoma
     人膀胱肿瘤中癌基因C-erbB-1/EGFR的分布及意义
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     The Clinical Significance of Telomerase Activity in Human Bladder Carcinoma
     以改良TRAP法检测人膀胱肿瘤组织中端粒酶活性表达的临床意义
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     Results Study in vitro indicated that BDI-1-PEA showed stronger selective cytotoxicity against human bladder carcinoma cell line E-J than free PEA or the mixture of BDI-1 and PEA.
     应用四甲基偶氮唑盐 (MTT)法初步检测其对人膀胱肿瘤细胞系E -J的选择性杀伤活性。 结果 BDI- 1-PEA结合物具有高效靶向杀伤膀胱肿瘤细胞的能力 ,优于游离PEA或PEA与BDI- 1的混合物。
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     Objective To construct the immunotoxin BDI-1-PEA and study its cytotoxicity against human bladder carcinoma in vitro.
     目的 构建新型免疫毒素BDI- 1-PEA ,并进行抗人膀胱肿瘤活性的初步研究测定。
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     Conclusion BDI-1-PEA conjugate is an effective immunotoxin against human bladder carcinoma and is a promising candidate for further clinical study.
     结论 新型免疫毒素BDI- 1-PEA有较高的选择性抗人膀胱肿瘤细胞的活性 ,有较高的研究和应用价值
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  “人膀胱肿瘤”译为未确定词的双语例句
     [Objective] To clone human bladder tumor E2F3 gene, construct its eukaryotic expression vector and expression in the BIU-87 cell.
     目的克隆人膀胱肿瘤组织E2F3基因及构建E2F3基因真核表达载体并研究其表达。
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     Expression of cell signal conducting molecule P36 in human bladder cancer
     细胞信号传导分子P36在人膀胱肿瘤中的表达及意义
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     p53 GENE MUTATION IN HUMAN BLADDER CANCER
     p53基因在人膀胱肿瘤中的突变
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     Expression and significance of protein kinase substrate P36 in humanbladder cancer
     蛋白激酶底物P36在人膀胱肿瘤中的表达及意义
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     pEGFP-E2F3 was identified by sequencing. Using liposome-mediated transfection, the eukaryotic expression vector pEGFP-E2F3 was transfected into BIU-87 cell.
     结果成功克隆人膀胱肿瘤组织E2F3基因、构建E2F3基因真核表达载体,转染后成功表达。
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  相似匹配句对
     p53 GENE MUTATION IN HUMAN BLADDER CANCER
     p53基因在膀胱肿瘤中的突变
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     A Study on the Relationship between Infection of Human Papillomavirus and the Incidence of Bladder Carcinoma
     乳头瘤病毒感染与膀胱肿瘤关系的探讨
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     Humans
    
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     Abnormal expression and clinical significance of muta-tion p53 gene on human bladder cancer
     突变型p53基因在膀胱肿瘤中的表达及临床意义
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     Expression and significance of protein kinase substrate P36 in humanbladder cancer
     蛋白激酶底物P36在膀胱肿瘤中的表达及意义
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  human bladder carcinoma
TBARS, Carnitine, and Reduced Glutathione Levels in Human Bladder Carcinoma
      
Expression of a mutant hTERT in human bladder carcinoma cell line T24 and its clinical significance
      
Apoptosis induced by ginsenoside Rg3 in a human bladder carcinoma cell line
      
Plasmids encoding each of the mutated SF-1 proteins were cotransfected with the StAR and HDL-R promoter constructs into human bladder carcinoma (HTB-9) cells in the presence or absence of dibutyryl cAMP.
      
Erythroid progenitor cells (BFUe: burst forming units-erythroid) are cultured in 1 ml of 0.35% agarose in IMDM with 30% FBS and conditioned medium from human bladder carcinoma cell line 5637 or recombinant interleukin 3.
      
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In order to study the relationship between the p53 gene mutation and human bladder can- cer,immunocytochemical and image analysis was used to detect bladder cancer samples taken from 58 cas- es. The findinge show that the positive rate of mutant p53 protein is 27.6%. Most of it is loclized in nu- cleus(87.5%)and small part in cytoplasm(12.5%). The positive rate of mutant p53 protein makes sig- nificant difference in pathological classification,clinical stage of carcinoma and prognosis (P<0. 05)....

In order to study the relationship between the p53 gene mutation and human bladder can- cer,immunocytochemical and image analysis was used to detect bladder cancer samples taken from 58 cas- es. The findinge show that the positive rate of mutant p53 protein is 27.6%. Most of it is loclized in nu- cleus(87.5%)and small part in cytoplasm(12.5%). The positive rate of mutant p53 protein makes sig- nificant difference in pathological classification,clinical stage of carcinoma and prognosis (P<0. 05). The result indicates that the p53 gene mutation is closely related to the biological action of human bladder cancer,and is an important indes for determining the invasivenes and prognosis of bladder cancer

为了研究p53基因突变与人膀胱肿瘤之间的关系,应用免疫组化结合图像分析对58例膀胱肿瘤标本进行检测。结果发现突变后的p53蛋白阳性率为27.6%。显色主要定位在细胞核上(87.5%),少部分在胞浆内(12.5%)。它的阳性率在肿瘤的病理分级,临床分期及预后等方面差异显著(P<0.05)。结果提示,p53基因突变与人膀胱肿瘤生物学行为之间关系密切,是判断膀胱肿瘤恶性程度及预后的一项重要指标。

Objective To study the reactivities of human bladder carcinoma to chemotherapeutic agents and screen the sensitive drugs for individuals. Methods The chemosensitivities of fresh bladder carcinoma samples from 27 patients to cisplatin,polyerga, mitomycin C, thiotepa,adriamycin and etoposide were determined by using a tetrazoliumbase decolorimetric assay(MTT assay). Results Ten cases(37.0%) were sensitive to 3 different drugs. They were DDP, polyerga, MMC, THT, ADM and VP16. Few patients were sensitive...

Objective To study the reactivities of human bladder carcinoma to chemotherapeutic agents and screen the sensitive drugs for individuals. Methods The chemosensitivities of fresh bladder carcinoma samples from 27 patients to cisplatin,polyerga, mitomycin C, thiotepa,adriamycin and etoposide were determined by using a tetrazoliumbase decolorimetric assay(MTT assay). Results Ten cases(37.0%) were sensitive to 3 different drugs. They were DDP, polyerga, MMC, THT, ADM and VP16. Few patients were sensitive to other drugs. The order of senditivity to drugs was approximately in accordance with clinical curative effect. Conclusion The result may be used for clinical reference in selecting drugs.

①目的研究人膀胱肿瘤对化疗药物反应性,筛选对个体敏感的化疗药物。②方法采用四氮唑蓝(MTT)法对手术切除的27例膀胱肿瘤新鲜标本进行顺铂(DDP)、保尔佳(polyerga)、丝裂霉素(MMC)、噻替哌(THT)、阿霉素(ADM)和足叶乙甙(VP-16)的抗癌药物敏感试验。③结果27例中对3种药物敏感者10例,占37.0%;敏感药物顺序依次为:DDP,polyerga,MMC,THT,ADM和VP-16,与临床治疗结果大致相符。④结论MTT法可以作为化疗药物敏感试验的检测方法,为临床科学合理地选择用药提供依据。

Objective\ To study preparation of N methyl N nitrosourea (MNU) and development of the experimental animal model of bladder tumors induced by MNU in rats. Methods\ Bladder tumors were induced in femal wistar rats by intravascular administration of the carcinogen, MNU that was synthesized with CH 3NH 2HCL. The morphological alterations in bladder epithelial cells were studied under light microscopy, scanning and transmission electron microscopy. Results\ The administration way of a total dose of 8 mg on...

Objective\ To study preparation of N methyl N nitrosourea (MNU) and development of the experimental animal model of bladder tumors induced by MNU in rats. Methods\ Bladder tumors were induced in femal wistar rats by intravascular administration of the carcinogen, MNU that was synthesized with CH 3NH 2HCL. The morphological alterations in bladder epithelial cells were studied under light microscopy, scanning and transmission electron microscopy. Results\ The administration way of a total dose of 8 mg on 4 fraction of 2 mg at 2 weekly intrvals produced a 100 % incidence of bladder tumor after 8 weeks. Histopathological characteristics of bladder tumor induced by MNU were basically similar to those of human bladder tumor. Conclusion\ Intravascular administration of MNU in rats provided a useful model for experimental studies on bladder tumor.\;

目的 研究N 甲基亚硝基脲 (MNU)制备方法及其诱发大白鼠膀胱肿瘤的作用。方法由甲胺盐酸盐合成诱癌剂MNU ,进行大白鼠膀胱灌注 2mg/次 ,每 2周 1次 ,共 4次 ,以光镜、扫描电镜、透射电镜等为观察手段 ,对其诱发的膀胱肿瘤进行观察。结果  8周诱发膀胱肿瘤率为 10 0 % ,其组织学检查及病理学特征与人膀胱肿瘤十分相似。结论 自制的MNU诱发的大白鼠膀胱肿瘤为比较理想的动物模型。

 
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