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基本核心
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  basic core
     Objective To investigate the distribution of hepatitis B virus (HBV) precore A1896 and basic core promoter(BCP)T1762/A1764 mutations in Guizhou area.
     目的调查贵州省乙型肝炎病毒(HBV)前C区A1896、基本核心启动子区(BCP) T1762/A1764变异分布。
短句来源
     The Clinical Significance of the Basic Core Promoter T~(1762)A~(1764)Mutation of Hepatitis B Virus
     乙型肝炎病毒基本核心启动子T~(1762)A~(1764)联合突变的临床意义
短句来源
     Objective To investigate the clinical characteristics and significance of HBV genome mutations in basic core promoter(BCP)—nt1762A→T and nt1764G→A—in chronic hepatitis B virus in children.
     目的 探讨儿童慢性乙肝病毒基本核心启动子 (BCP)基因双变异 (nt176 2A→T和nt176 4G→A)的临床特征和意义。
短句来源
     Objects To establish a mismatched polymerase chain reaction restricted fragment length polymorphism(mPCR-RFLP) method for the detection of hepatitis B virus (HBV) mutations in precore A1896,basic core promoter(BCP)T1762/A1764 and compare the method with direct sequencing to evaluate its application value.
     目的建立错配聚合酶链反应-限制性片段长度多态性(mPCR-RFLP)检测乙型肝炎病毒(HBV)前C区A1896、基本核心启动子(BCP)T1762/A1764双变异的方法,与直接测序法比较,评估其应用价值。
短句来源
     Objective To investigate the relationship of HBV Lumivudine resistant and HBV genotypes and basic core promoter(BCP) mutation.
     目的 了解拉米夫定耐药与HBV基因型及HBV基本核心启动子 (BCP)突变之间的关系。
短句来源
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  the basic core
     The Clinical Significance of the Basic Core Promoter T~(1762)A~(1764)Mutation of Hepatitis B Virus
     乙型肝炎病毒基本核心启动子T~(1762)A~(1764)联合突变的临床意义
短句来源
     Objective:To study the T 1762A 1764 mutation in the basic core promoter (BCP) region of hepatitis B (HBV) in Nantong viral hepatitis B patients.
     目的 :研究乙型肝炎患者乙型肝炎病毒 (HBV)基本核心启动子 (BCP) T1 76 2 A1 76 4联合突变情况及其临床意义。
短句来源
     Objective To investigate the variation of the basic core promoter(BCP) of HBV and clarify the significance of HBV quasispecies groups in the patients with chronic HBV. Methods A set of specific primers was synthesized according to HBV DNA sequence of Chinese strain.
     目的 通过对乙型肝炎病毒 (HBV)基本核心基因启动子 (BCP)变异的研究 ,阐明HBV准种在慢性感染者中存在的意义。
短句来源
     Along with the rapid socio-economic development in our country, the increasing of cities number and population in cities, the city scale expands unceasingly, urbanized phenomenon acceleration, the city research appears importantly day by day, and the urban spatial structure is the main domain and the basic core which the city research worker studies.
     随着我国社会经济的快速发展,城市的数量、人口在不断增加,城市规模在不断扩大,城市化现象加速,对城市的研究显得日益重要,而城市空间结构是城市研究工作者研究的主要领域和基本核心
短句来源
     Objective To study the distribution of hepatitis B virus(HBV) genotype and its clinical significance and the influence of the basic core promoter,precore mutations and genotypes of HBV on advance of liver disease.
     目的应用测序列的方法,探讨乙型肝炎病毒(HBV)基因型在南京地区的流行病学状况和HBV基因型与基本核心启动子(BCP)及前C区变异对疾病进展的影响。
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  “基本核心”译为未确定词的双语例句
     After sequence amplification and analysis of the core gene,50 specimens were found belonging to genotype C,and the others were genotype B.The double mutation in BCP(T1762/A1764) was obviously more frequent in genotype C(38%) than that in genotype B patients(12.9%,P<0.05).
     C基因型的基本核心启动子BCP T1762/A1764的突变率(38%)明显高于B基因型(12.9%,P<0.05);
短句来源
     Possible gene mutations were searched for in site 1896 of pre-C section, sites 1762,1764 of BCP section and sites 528,552 of P section with DNA chip method based upon membrane colouration.
     方法:应用聚合酶链反应扩增乙型肝炎患者血清中HBVDNA,采用膜显色DNA芯片法检测HBVDNA前C区1896位,基本核心启动子区(BCP区)1762、1764位,P区528、552位突变。
短句来源
     JPEG2000part1defines the core coding system,namely,the baseline system. Part2defines extensions to the baseline system.
     JPEG2000标准中的Part1给出了JPEG2000的基本核心系统,Part2提供了基本系统的多种扩展功能。
短句来源
     Objective To probe into the clinical characteristic of the HBeAg-negative chronical hepatitis-B(e-CHB for short)and its relationships with the G1896A mutation in the precore and with the A1762T/G1764A twin-mutation in the basal core promoter(BCP for short).
     目的探讨HBeAg阴性慢性乙型肝炎(以下简称e-CHB)的临床特点及与前C区G1896A变异及基本核心启动子(BCP)区A1762T/G1764A双变异的关系。
短句来源
     Methods:HBV-DNA extracted by PCR from two groups of chronic hepatitis patients with serum HBV-DNA positive,including HBeAg and HBeAb positive 30 respectively, was detected to find HBV mutants in basal core gene promoter (nt 1762,nt 1764) and pre-core/core region (nt 1896,nt1899) using sandwich hybridization-ELISA assay on microplate.
     方法 :HBV -DNA阳性且e抗原 /或e抗体阳性的慢性乙型肝炎患者各 30例 ,以PCR结合微板核酸杂交 -ELISA方法检测乙肝病毒前C基因 (nt 1896、nt 1899)及其基本核心启动子 (BCP ,nt 176 2、nt 176 4)变异。
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  basic core
In this study, a search was therefore made for nucleotide mutations in the basic core promoter (BCP) and amino-acid substitutions in the precore/core region of HBV infecting patients with CAH or with acute hepatitis.
      
In Case 1 (HBeAg-positive; wild type of basic core promoter [BCP] and precore [PreC]), fluctuations of HBV DNA and HBeAg state were accompanied by mutations of the BCP and PreC.
      
According to the first strategy, a basic core and additional logic for a custom device are integrated onto the same die.
      
A Basic Business Information Entity is derived from a Basic Core Component.
      
A basic core requirement for supporting any of these models is to be able to create a new active entity in the system.
      
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  the basic core
In this study, a search was therefore made for nucleotide mutations in the basic core promoter (BCP) and amino-acid substitutions in the precore/core region of HBV infecting patients with CAH or with acute hepatitis.
      
Depending on the student's educational background, the basic core courses can be waived.
      
In many rural communities of developing countries, the use of remedies based on traditional medicine form the basic core of health care.
      
In the spring of 2005, the basic core and the first important modules of the system were in place after thorough testing.
      
In late September the basic core description work started with our primary core, 2B.
      
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Tuili is a programming language designed for logical inference. In its implementation, it is essential to build multiple inference engines with different inference capabilities and to make them work in acooperative way. The strategies of constructing the multiple inference engines and the main algorithms used for implementing them are presented.

在逻辑型知识推理语言Tuili的实现中,基本核心是构造不同推能力的多个推理机并使之协同工作.针对这一问题,本文提出了实用的构造多推理机的方法和策略,并给出实现推理机的主要算法.

Although superstring theory is still in a state of rapid development,the essence of the theory is now well established.In this paper,the developmental history of superstrings is discussed.Fundamental theories of superstrings are intioduced,the recent progresses on the subject are reviewed,especially emphasize on the possibility of superstring as a unified theoryof all fundamental interactions.And some serious questions which superstring theories meet are pointed out.

虽然超弦理论现在仍处于迅速发展阶段,但是这个理论的基本核心已经确立。本文讨论了超弦理论的历史发展,介绍了超弦的基本理论,评述了超弦理论的最新重大发展及其意义和新的发展方向,特别强调超弦理论作为实现自然界中所有相互作用的统一理论的可能性,指出了该理论所面临的严重困难及其在哲学上的影响。

In this study,linearized genome containing the entire HBV transcriptional units were constructed,which initiated from the basic core promoter (Cp) or its upstream regulatory sequences.The transcriptional unit from Cp was sufficient for the transcription,replication and expression of HBV genome.The upstream regulatory sequences of Cp,overlapping with EN Ⅱ,had a strong stimulating effect on the replication of HBV progeny DNA.However,a region upstream EN Ⅱ and Cp (nt 1403-1633) could suppress this activation.It...

In this study,linearized genome containing the entire HBV transcriptional units were constructed,which initiated from the basic core promoter (Cp) or its upstream regulatory sequences.The transcriptional unit from Cp was sufficient for the transcription,replication and expression of HBV genome.The upstream regulatory sequences of Cp,overlapping with EN Ⅱ,had a strong stimulating effect on the replication of HBV progeny DNA.However,a region upstream EN Ⅱ and Cp (nt 1403-1633) could suppress this activation.It indicated that the transcription and replication of HBV genome depended on both positive and negative regulation.In addition,there were regulatory elements located on upstream of Cp related to the hepatocyte specificity of HBV gene expression.

构建了线性化的、从基本核心启动子(Cp)开始并有不同长度Cp上游顺序的、含完整转录单元的HBV基因组克隆,以研究Cp及其上游顺序对HBV基因表达的调控及对HBV子代DNA复制的影响。发现从基本核心启动子Cp开始的HBV转录单元能够有效地起始3.5kbmR-NA转录。Cp上游ENI顺序对子代DNA复制有极强的刺激作用,而ENⅡ更上游顺序对ENⅡ的刺激作用又有所抑制,证明Cp的转录受其上游顺序的正负双重调控。另外,Cp上游还存在与HBV基因表达的细胞专一性有关的调控顺序。

 
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