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细胞信号传递的
相关语句
  cell signal pathway
     The Pulsed Electric Field Effect on the Cell Signal Pathway Mediated by Insulin
     胰岛素介导的脉冲电场对细胞信号传递的影响
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  “细胞信号传递的”译为未确定词的双语例句
     GF14 widely occurs in plant species functioning as aregulatory protein in cell signal transduction. A partial sequence, 413 bp in length , was cloned from the bulbs of F.
     GF14蛋白是广泛存在于植物中的参与细胞信号传递的调节蛋白,采用RT-PCR技术克隆了川贝母的一个413bp的cDNA片段。
短句来源
     By catalyzing substrate protein tyrosine phosphorylation, tyrosine protein kinase participated in cell signal transduction. The protein phosphorylation and dephos-phorylation are key to cell signal transduction, between cell growth, differentiation, transfer and tyrosine phosphorylation status are closely related.
     TPK通过对底物蛋白质酪氨酸残基的磷酸化,参与细胞信号传递,而蛋白质的磷酸化和去磷酸化反应是细胞信号传递的关键变化,细胞的生长、分化、转移行为与细胞内蛋白质酪氨酸磷酸化水平紧密相关。
短句来源
  相似匹配句对
     Signal Regulation of B Cell Homeostasis
     B细胞稳态的信号调节
短句来源
     Cellular signal transduction and cancer
     细胞信号传导和肿瘤
短句来源
     The Pulsed Electric Field Effect on the Cell Signal Pathway Mediated by Insulin
     胰岛素介导的脉冲电场对细胞信号传递的影响
短句来源
     -catenin and TCF4 for the Wnt signaling pathway was determined by TOP luciferase reporter assays.
     利用TOP荧光素酶报告质粒检测了肝癌细胞中Wnt途径信号传递的异常增强。
短句来源
     Study on Erythropoietin - Mediated Early Signal Trarisduction
     红细胞生成素介导的早期信号传递的研究
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ecent studies of cell biophysics have been in-troduced about cell ultrastructure effects ofphysical factors on living cells, cellular motili-ties, ion channels and cellular signalling. Someprogress in methodology for studying livingcells are also reviewed. It has been emphasizedthat the main purpose of cell biophysics is tounderstand the nature of the living cell in orderto explain why and how the cell is alive. Ac-cordingly. some questions and problems onprinciples and methodology have been dis-cussed in this...

ecent studies of cell biophysics have been in-troduced about cell ultrastructure effects ofphysical factors on living cells, cellular motili-ties, ion channels and cellular signalling. Someprogress in methodology for studying livingcells are also reviewed. It has been emphasizedthat the main purpose of cell biophysics is tounderstand the nature of the living cell in orderto explain why and how the cell is alive. Ac-cordingly. some questions and problems onprinciples and methodology have been dis-cussed in this article as well.

概括介绍了近几年来细胞生物物理学在细胞的精细结构研究、外界物理因素对细胞作用的研究、细胞运动的研究、细胞膜的离子通道、细胞的信号传递以及在研究方法等方面所取得的部分进展,并就如何实现细胞生物物理学的研究目标提出了自己的看法。

For investigating the roles of adhesion molecules in T cell were activation and the mechanism, T cells were stimulated with monocolonal antibodies directed at TCR-CD3 complex, LFA-1, LFA-2, CD44 and CD45 molecules, and Fc_γ RⅡ positive or negative tumor cells. In addition, T Cells or K562 cells were incubated with the indicated McAbs for inhibition assays. Amounts of IFN-γ produced by T cells under the stimulation and inhibition was quantitated as the marker of T cell activation. Our data suggested that T cell...

For investigating the roles of adhesion molecules in T cell were activation and the mechanism, T cells were stimulated with monocolonal antibodies directed at TCR-CD3 complex, LFA-1, LFA-2, CD44 and CD45 molecules, and Fc_γ RⅡ positive or negative tumor cells. In addition, T Cells or K562 cells were incubated with the indicated McAbs for inhibition assays. Amounts of IFN-γ produced by T cells under the stimulation and inhibition was quantitated as the marker of T cell activation. Our data suggested that T cell activation is dependent on the cross-linking of the TCR-CD3 complex. The binding of four adhesion molecules to their counter receptors resulted not only in cell-cell adhesion, but also in signal transduction by functioning as independent costimulators.

为了解粘附分子(Adhesionmolecules)在T细胞激活中的作用及其机制,作者采用TCR-CD3复合物、LFA-1、LFA-2、CD44和CD45特异性单克隆抗体刺激,FcγRII阳性或阴性肿瘤细胞刺激,以及刺激阻断的方法,以IFN-γ定量检测作为T细胞激活的标志,研究了TCR-CD3复合物交联(Cross-linking),交联的不同形式,LFA-1、LFA-2、CD44和CD45分子对T细胞激活的影响及其机制。结果提示:TCR-CD3复合物的持久性交联是T细胞体外激活的必要条件,上述4种粘附分子是T细胞激活的共刺激分子,其作用机制不仅是细胞间的粘附,而且还作为各自独立的刺激分子影响T细胞的信号传递。

he results ofphosphorylation

在sCD23促T细胞增殖的最佳条件下,体外渗透化的活化T细胞经亲和纯sCD23的刺激后,比阴性对照多出6条发生磷酸化的蛋白带,分子量分别为>100kD、100kD、88kD、84kD、76kD和52kD。用FACS分析sCD23效应靶细胞中效应亚群的特征,结果显示:亲和层析纯sCD23可促使预活化T细胞中CD4 ̄+CD8 ̄-与CD4 ̄-CD8 ̄+亚群的比值由阴性对照的1.08增高到1.55。按细胞体积大小进一步取门分析,结果表明,该效应主要反映在小体积T细胞群中。本试验结果提示,sCD23可能参与T细胞的信号传递过程;sCD23的效应靶细胞可能是CD4 ̄+T细胞亚群。

 
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