助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   凋亡率及fas 的翻译结果: 查询用时:0.204秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

凋亡率及fas
相关语句
  apoptosis fas
     Apoptosis, Fas expression were detected by Tunnel method and S-P method respectively.
     用Tunnel法、S -P法检测DEX刺激前、后TEC的凋亡率及Fas表达阳性率。
短句来源
     Methods Thyroid tissues were obtained from 7 patients with GD and 3 healthy subjects who died accidentally. Thyrocytes were cultured in Eagle′s medium. Apoptosis, Fas expression and Fas, sFas, Fas-L mRNA levels in thyrocytes were detected by flow cytometry and semi-quantitative RT-PCR, sFaswasalsodeterminedin supernatant of cultured thyroid cells by ELISA.
     方法甲状腺组织取自 7例GD手术患者和 3例意外死亡健康个体 ,采用原代甲状腺细胞 (TEC)培养技术、流式细胞术、ELISA及半定量RT PCR法检测TEC凋亡率及Fas、sFas和Fas L的表达情况。
短句来源
  “凋亡率及fas”译为未确定词的双语例句
     (3)the apoptsis rate and the expression of Fas and bcl-2 were increased with the prolonged action time of AngII, and they ranked the highest at 18 and 6 hours, respectively(1.43±0.21, 18.56±3.68; 1.21±0.32, 8.62±1.54;2.53±0.71, 15.41±1.63 P<0.01);
     ③随着AngII作用时间的增加,VSMC凋亡率及Fas、bcl-2基因的表达均增加(1.43±0.21vs18.56±3.68,Fas:1.21±0.32vs8.62±1.54,bcl-2:2.53±0.71vs15.41±1.63,P<0.01);
短句来源
     The apoptosis rates and expression levels of Fas and FasLmRNA were higher than those of the OVX control group in the two concentrations (10-3 μmol/L,10-2 μmol/L)(allP<0.01).
     与去势对照组相比,E2在10-3μmol/L、10-2μmol/L浓度时凋亡率及Fas、FasL基因的表达增高(均P<0.01)。
短句来源
     Results: (1)with the increasing concentration of AngII, the apoptosis rate and the expression of Fas were increased and reach the highest at a 10-5mol/L-concentration(19.71±3.03; 14.67±1.39), and the expression of bcl-2 peaked at a 10-6mol/L-concentration(16.65±1.42);
     结果:①随着AngII作用浓度的增加,VSMC凋亡率及Fas,bcl-2基因的表达量均增加(2.35±0.56vs19.71±3.03;Fas:1.36±0.32vs14.67±1.39;bcl-2:2.35±0.51vs16.65±1.42,P<0.01);
短句来源
     Results: Except for thegroup which concentration of E2 was the 1owest (10-5 μmol/L), the apoptosis rates and expression levels of Fas andFasL mRNA were higher than those of the young group.
     结果:除最低浓度(10-5μmol/L)外,去势+E2组凋亡率及Fas、FasL基因的表达都高于青年组(P<0.05);
短句来源
     Methods The expression rates of Fas and FasL and apoptosis rates of peripheral blood T and B lymphocytes were detected by flow cytometry (FCM) in 30 active SLE patients and 30 inactive SLE patients and 30 healthy controls.
     方法采用流式细胞术(FCM)检测了30例SLE活动期患者、30例SLE非活动期患者和30名正常人外周血T、B淋巴细胞的凋亡率及Fas、FasL表达率。
短句来源
更多       
  相似匹配句对
     There were significant relation between the decrease of Fas positive rate and increase apoptosis.
     Fas阳性下降与凋亡增加相关。
短句来源
     Apoptosis rate shows an increasing trend;
     凋亡呈现增加的趋势;
短句来源
     Determination and significance of Fas and apoptotic rates in nutritional anemia
     营养性贫血患者骨髓肿瘤坏死因子Fas凋亡的测定临床意义
短句来源
     Flurorescence staining was used to detect the percentage of apoptosis.
     荧光染色检测凋亡;
短句来源
     Objective To explore the relationship between Fas and apoptotic rates and pathological mechanism of nutritional anemia.
     目的 探讨肿瘤坏死因子Fas凋亡与营养性贫血发病机制的关系。
短句来源
查询“凋亡率及fas”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
没有找到相关例句


Objective To investigate the function of eosinophil apoptosis and regulation of glucocortico steroids on IL 5 and GM CSF expression in peripheral blood mononuclear cells (PBMCs) in glucocorticoid resistant asthmatic patients Methods Eosinophils (EOS) and PBMCs isolated from glucocorticoid sensitive (SS, 15 cases) and resistant (SR, 30 cases) asthmatic subjects were cultured and treated with dexamethasone (DXM) in vitro Concentrations of IL 5 and GM CSF were determined by ELISA in the supernatants...

Objective To investigate the function of eosinophil apoptosis and regulation of glucocortico steroids on IL 5 and GM CSF expression in peripheral blood mononuclear cells (PBMCs) in glucocorticoid resistant asthmatic patients Methods Eosinophils (EOS) and PBMCs isolated from glucocorticoid sensitive (SS, 15 cases) and resistant (SR, 30 cases) asthmatic subjects were cultured and treated with dexamethasone (DXM) in vitro Concentrations of IL 5 and GM CSF were determined by ELISA in the supernatants recovered in sham and DXM treated cells The rates of EOS apoptosis and Fas antigen expression were documented via flow cytometer in sham, DXM treated and PBMC supernatant treated groups respectively Results There were no statistical significant differences of the concentrations of both IL 5 and GM CSF in sham cultured PBMC supernatants between SS and SR groups [(196±68) μg/L vs (235±98 ) μg/L IL 5 ( P >0 05), (325±110) μg/L vs (356±131) μg/L GM CSF ( P >0 05); SS versus SR groups, respectively] There were statistically significant decreases in both IL 5 and GM CSF after DXM exposure in SS group [(196±68) μg/L vs (147±62) μg/L IL 5 ( P <0 01); (325±110) μg/L vs (270±97) μg/L GM CSF ( P <0 01)] In contrast, there were no significant differences in both IL 5 and GM CSF after DXM exposure in SR group Baseline rates of both EOS apoptosis and Fas antigen expression were statistically significant different between SS and SR groups [(67±21)% vs (33±17)% the rate of EOS apoptosis ( P <0 001); (54±23)% vs (27±15)% the rate of Fas antigen expression ( P <0 001), SS versus SR groups, respectively] A dramatic increase in EOS apoptosis after DXM exposure was observed in SS group [(67±21)% vs (89±20)% ( P <0 01), baseline vs DXM exposure, respectively], but there was no significant change in Fas antigen expression There were no significant changes in both EOS apoptosis and Fas antigen expression in SR group after DXM exposure. Conclusions These data suggest that EOS compromised apoptosis might exist and could not be affected by glucocorticoid induction in SR asthma On the other hand, Th2 cytokine over expression could not be inhibited by glucocorticoid in SR group in vitro

目的 观察激素抵抗型 (SR)哮喘是否存在嗜酸细胞 (EOS)凋亡功能的异常及促炎症细胞因子白细胞介素 5 (IL 5 )和粒 巨噬细胞集落刺激因子 (GM CSF)的调节作用。方法 分离SR(15例 )、激素敏感型 (SS ,30例 )两组哮喘患者外周血单个核细胞 (PBMCs)及EOS ,体外培养后测定 :(1)PBMCs在糖皮质激素处理前、后分泌细胞因子的能力 ;(2 )自发的或糖皮质激素诱导的或用PBMCs培养上液处理后的EOS凋亡率及Fas抗原表达率。结果  (1)糖皮质激素处理前SS组与SR组患者PBMCs分泌IL 5水平 (μg/L)分别为 196± 6 8、2 35± 98;GM CSF分泌水平 (μg/L)SS组和SR组患者分别为 32 5± 110、35 6± 131,两组比较差异均无显著性 (P >0 0 5 )。地塞米松处理后与处理前比较 ,SR组IL 5水平为 (2 10± 75 ) μg/L ,差异有显著性 (P <0 0 1) ;GM CSF为 (312± 147) μg/L ,差异有显著性 (P >0 0 1) ;SS组IL 5为 (147± 6 2 ) μ...

目的 观察激素抵抗型 (SR)哮喘是否存在嗜酸细胞 (EOS)凋亡功能的异常及促炎症细胞因子白细胞介素 5 (IL 5 )和粒 巨噬细胞集落刺激因子 (GM CSF)的调节作用。方法 分离SR(15例 )、激素敏感型 (SS ,30例 )两组哮喘患者外周血单个核细胞 (PBMCs)及EOS ,体外培养后测定 :(1)PBMCs在糖皮质激素处理前、后分泌细胞因子的能力 ;(2 )自发的或糖皮质激素诱导的或用PBMCs培养上液处理后的EOS凋亡率及Fas抗原表达率。结果  (1)糖皮质激素处理前SS组与SR组患者PBMCs分泌IL 5水平 (μg/L)分别为 196± 6 8、2 35± 98;GM CSF分泌水平 (μg/L)SS组和SR组患者分别为 32 5± 110、35 6± 131,两组比较差异均无显著性 (P >0 0 5 )。地塞米松处理后与处理前比较 ,SR组IL 5水平为 (2 10± 75 ) μg/L ,差异有显著性 (P <0 0 1) ;GM CSF为 (312± 147) μg/L ,差异有显著性 (P >0 0 1) ;SS组IL 5为 (147± 6 2 ) μg/L ,差异有显著性 (P <0 0 1) ,GM CSF为 (2 70± 97) μg/L ,差异有显著性 (P <0 0 5 )。 (2 )SS组与SR组EOS在体外培养时均发生不同程度的凋亡。EOS基础凋亡率SS组为 (6 7± 2 1) % ,SR组为 (33± 17) % ,两组与诱导前比较差异有显著性 (P <0 0 0 1)。Fas抗原表达率SS组为 (5 4± 2 3) % ,SR组为

: Objective To study the relation between the expression of Fas/Fas-L and heat stress-induced apoptosis of the thymocytes in vitro. Methods The expression of Fas/Fas-L and apoptotic rate of the thymocytes were assayed by flow cytometry. Results Both the apoptotic rate of and the expression of Fas and Fas-L in the thymocytes were increased in a time-dependent manner in vitro, and there was a significant relation between their increases. Conclusion Fas and Fas-L are both important to mediate heat stress-induced...

: Objective To study the relation between the expression of Fas/Fas-L and heat stress-induced apoptosis of the thymocytes in vitro. Methods The expression of Fas/Fas-L and apoptotic rate of the thymocytes were assayed by flow cytometry. Results Both the apoptotic rate of and the expression of Fas and Fas-L in the thymocytes were increased in a time-dependent manner in vitro, and there was a significant relation between their increases. Conclusion Fas and Fas-L are both important to mediate heat stress-induced apoptosis of thymocytes in vitro.

目的 探讨体外热应激诱导小鼠胸腺细胞凋亡与Fas、Fas-L表达的关系。方法 用流式细胞术检测体外热应激后再培养的胸腺细胞不同时间的凋亡率及Fas、Fas-L表达阳性率。结果 体外热应激诱导胸腺细胞的凋亡率和Fas及Fas-L表达阳性率均呈时间依赖性增高,体外热应激诱导胸腺细胞Fas/Fas-L的表达与凋亡明显相关。结论 Fas与Fas-L是介导体外热应激损伤胸腺细胞凋亡的重要分子。

Aim To study the relationship between the expressions of Fas, Fas-L and the spontaneous apoptosis of thymocytes in vitro. Methods The expressions of Fas, Fas-L and the apoptotic rate of thymocytes were assayed by now cytometry. Results The apoptosis and the Fas expression of thymocytes of fifferent culture times in vitro were increased time-dependently in vitro. The Fas-L expression of thymocytes cultured for 24 h was also significant increase. There was significant corelation between the increase of Fas expression...

Aim To study the relationship between the expressions of Fas, Fas-L and the spontaneous apoptosis of thymocytes in vitro. Methods The expressions of Fas, Fas-L and the apoptotic rate of thymocytes were assayed by now cytometry. Results The apoptosis and the Fas expression of thymocytes of fifferent culture times in vitro were increased time-dependently in vitro. The Fas-L expression of thymocytes cultured for 24 h was also significant increase. There was significant corelation between the increase of Fas expression and the increase of apoptosis of thymocytes,in vitro. Conclusion Fas is an important molecule which mediates spontaneous apoptosis of thymocytes cultured in vitro.

目的探讨体外培养的胸腺细胞表达Fas、Fas-L与自发凋亡的关系。方法应用流式细胞术,检测体外培养不同时间的胸腺细胞的凋亡率及Fas、Fas-L表达的阳性率。结果体外培养的胸腺细胞自发凋亡率和Fas表达阳性率,均呈时间依赖性增加, Fas-L在体外培养24 h时明显增加。体外培养的胸腺细胞Fas的表达与自发凋亡明显相关。结论Fas是介导体外培养的胸腺细胞自发凋亡的重要分子。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关凋亡率及fas的内容
在知识搜索中查有关凋亡率及fas的内容
在数字搜索中查有关凋亡率及fas的内容
在概念知识元中查有关凋亡率及fas的内容
在学术趋势中查有关凋亡率及fas的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社