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临床总有
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  clinical effective
    Total clinical effective rates were 73.9% in quetiapine group and 91.8% in risperidone group,and there was significant difference between two groups.
    临床总有效率 :奎硫平组 73.9% ,利培酮组 91.8% ,两组间疗效有显著性差异 (P <0 .0 5 )。
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    There were insignificant differences in the decreasing rate of HAMA score and the total clinical effective rate between the study group [(59.03±24.78)%and 72%] and the control group [(57.30±25.33)%and 67%] (P >0.05).
    对照组HAMA减分率为(57.30±25.33)%,临床总有效率为67%,两组比较差异无显著性意义艹卓艹卓艹卓艹卓艹卓(P>0.05)。
短句来源
    ① The decreasing rate of excitement factor score and change of total score of PANSS: At 72 hours after treatment, the total score of excitement factor of PANSS in the Ziprasidone group was significantly reduced as compared with that before treatment, the decreasing rate of score was (47.33 ±26.07)%, and the total clinical effective rate was 47.33%.
    ①阴性与阳性症状量表兴奋因子减分率及总分的变化:治疗72h后,甲磺酸齐拉西酮组的阴性与阳性症状量表兴奋因子总分较治疗前明显降低,减分率为(47.33±26.07)%,临床总有效率为47.33%;
短句来源
    The total score of excitement factor of PANSS in the Haloperidol group was also significantly reduced as compared with that before treatment, the decreasing rate of score was (48.53±21.99)%, and the total clinical effective rate was 48.53%. There were no significant differences between the two groups (P > 0.05).
    氟哌啶醇组阴性与阳性症状量表兴奋因子总分较治疗前同样明显降低,减分率为(48.53±21.99)%,临床总有效率为48.53%,两组比较差异无显著性(P>0.05)。
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    Clinical effective rate were 73.15% for tandospirone, 76.58% for buspirone. The side effect of two groups are similar. The incidences of side effect were 33.63% and 30.77% , respectively.
    临床总有效率坦度螺酮组为73.15%、丁螺环酮组为76.58%,坦度螺酮组的药物不良反应发生率与丁螺环酮组相当,分别为33.63%和30.77%。
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  “临床总有”译为未确定词的双语例句
    Results The total effective rate was 93% and effectual rate 78%.
    结果利培酮治疗首发精神分裂症的临床总有效率为93%,显效率78%。
    RESULTS: The response rates were 68.6% and 60.0% for risperidone and haloperidol, respectively (P>0.05).
    结果:利培酮和氟哌啶醇的临床总有效率分别是68.6%和60.0%(P>0.05)。
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    Results The rate of patients with re- admission was 78.79%(26/33) and the responded rate to clozapine was 84.84%. But side effects rate and serious adverse were more and worse.
    结果  33例精神分裂症患者的再入院率为 78.79% (2 6 /33) ,临床总有效率为84 .84 % ,但临床副作用多而严重。
短句来源
    By the PANSS score reduction rate, the clinical effectiveness rate is: quetiapine was 61.61% and chlorpromazine was 64.81%.
    根据PANSS减分率评定临床总有效率,奎硫平组的有效率为61.61%,氯丙嗪组的有效率为64.81%,两组之间无显著性差异;
短句来源
    RESULTS: At end of the treatment, the total effective rate of risperidon for SC was 91 % and remarkable effective rate was 78 %.
    结果 :利培酮治疗SC的临床总有效率为 91 % ,显效率 78%。
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  clinical effective
Hypoxanthine 600 mg/kg and niacin 100 mg/kg was applied to hyperuricemic mice by gastrogavage to establish the animal models.Results: The clinical effective rate of the treated group was 95.0% and that of the control 90.0%.
      
After treatment of two months, the clinical effective rate in acupuncture plus drug group was 51.9%, and the total effective rate was 88.5%, both of them were better than those in control group (P>amp;lt;0.05).
      


The punpose of this study is to assess the efffectiveness of sodium valproate in the treatment of mental illness. One hundrad and fifty five psychiatric patients were treated openly by sodium valproate for 8 weeks, with 800-3000 mg/day. All of patients were rated blindly on CGI, TESS by two trained poychiatrists before the treatment, and in the first, second, fourth, sixth and eighth weeks after the tratment. The total improvement rate is 60%. Sodium valproate was found to be more effective in the treatment...

The punpose of this study is to assess the efffectiveness of sodium valproate in the treatment of mental illness. One hundrad and fifty five psychiatric patients were treated openly by sodium valproate for 8 weeks, with 800-3000 mg/day. All of patients were rated blindly on CGI, TESS by two trained poychiatrists before the treatment, and in the first, second, fourth, sixth and eighth weeks after the tratment. The total improvement rate is 60%. Sodium valproate was found to be more effective in the treatment of elation irritability, insomnia and auditory hallucination and delusion, but to be less effective in the treatment of thought disturbance, apathy, social withdrawal. No serious further comprehensive study is required to verify the effectiveness of sodium valproate in the treatment of mental illness adverse effects in observed.

用丙戊酸钠治疗155例精神病人,疗程8周,临床总有效率60%。对情感高涨、易激惹、失眠疗效较好;对幻听、妄想有一定的疗效;对思维联想障碍、情感淡漠、生活懒散疗效欠佳。使用中未见严重不良反应。

Objective To verify the efficacy and side effects of domestic manufactured quetiapine on schizophrenia Methods Patients who met CCMD 2 R criteria for schizophrenia were randomized into two groups: quetiapine group ( n =114) and chlorpromazine (CPZ) group ( n =107) in a double blind, double dummy study The range of dosage for the two experiment drugs was 200 800 mg/d, the treatment duration was 8 weeks The PANSS, BPRS, CGI, TESS and related lab tests were employed for assessing the treatment effectiveness...

Objective To verify the efficacy and side effects of domestic manufactured quetiapine on schizophrenia Methods Patients who met CCMD 2 R criteria for schizophrenia were randomized into two groups: quetiapine group ( n =114) and chlorpromazine (CPZ) group ( n =107) in a double blind, double dummy study The range of dosage for the two experiment drugs was 200 800 mg/d, the treatment duration was 8 weeks The PANSS, BPRS, CGI, TESS and related lab tests were employed for assessing the treatment effectiveness and side effects Results At the end of treatments, the scores of PANSS and BPRS in both treatment groups decreased significantly compared with baseline ( P <0 01), and the decreasing rates on PANSS were (65 9±27 8)% in quetiapine group and (66 5±26 4)% in CPZ group Total clinical effective rates were 68 1% in quetiapine group and 69 6% in CPZ group, which was no significant difference between two groups However, patients in quetiapine group reported much fewer side effects than those in CPZ group, especially in the items of reduced activities, tremor, akathisia, acute dystonia, dry month, blur sight, constipation, and dizziness on TESS ( P <0 05) Conclusion Quetiapine has similar efficacy to CPZ, but has less side effects Quetiapine is an effective antipsychotic drug with fewer side effects

目的 验证奎硫平治疗精神分裂症的疗效及安全性。方法 将 2 2 1例精神分裂症患者随机分为奎硫平组 ( 1 1 4例 )和氯丙嗪组 ( 1 0 7例 ) ,进行多中心双盲双模拟对照研究 ,两药治疗剂量均为 2 0 0~ 80 0mg d ,疗程 8周。疗效指标包括阳性和阴性症状量表 (PANSS)、简明精神病评定量表(BPRS)、临床总体印象量表 (CGI)。不良反应指标为不良反应量表 (TESS)及有关实验室检查。结果治疗结束时 ,两组PANSS和BPRS评分较入组时均显著减低 (P <0 0 1 ) ;PANSS减分率 :奎硫平组为( 65 9± 2 7 8) % ,氯丙嗪组为 ( 66 5± 2 6 4 ) % ;临床总有效率 :奎硫平组 68 1 % ,氯丙嗪组 69 6% ;两组疗效差异无显著性。奎硫平组的不良反应较氯丙嗪组少 ,其中活动减少、震颤、扭转痉挛、静坐不能、口干、视物模糊、便秘、头晕的发生率显著少于氯丙嗪组 (P <0 0 1或 0 0 5)。结论 国产奎硫平治疗精神分裂症的疗效与氯丙嗪相似 ,某些不良反应较氯丙嗪轻而少 ;是一种有效、耐受性好的抗精神病药。

OBJECTIVE: To compare the efficacy and safety of risperidone and haloperidol in the treatment of schizophrenic. METHODS:A hundred and one schizophrenic patients were randomly assigned to two groups given oral doses of risperidone (2 to 6mg·d-1, 51 cases) or haloperidol (6 to 18 mg·d-1, 50 cases) in a double-blind parallel way for 6 weeks. PANSS and a 4-score clinical impression of efficacy were used to measure the efficacy. Simpson-Angus Scale (SAS) and Treatment Emergent Side-Effect Scale (TESS) were used to...

OBJECTIVE: To compare the efficacy and safety of risperidone and haloperidol in the treatment of schizophrenic. METHODS:A hundred and one schizophrenic patients were randomly assigned to two groups given oral doses of risperidone (2 to 6mg·d-1, 51 cases) or haloperidol (6 to 18 mg·d-1, 50 cases) in a double-blind parallel way for 6 weeks. PANSS and a 4-score clinical impression of efficacy were used to measure the efficacy. Simpson-Angus Scale (SAS) and Treatment Emergent Side-Effect Scale (TESS) were used to measure adverse effects. RESULTS: The response rates were 68.6% and 60.0% for risperidone and haloperidol, respectively (P>0.05). Both of the drugs were effective in the positive, negative and general psychopathological symptoms while no significant differences were detected between groups. The SAS total scores were significantly lower in risperidone than in haloperidol group. Less muscular tension, tremor, akathesia were seen in risperidone than in haloperidol group (P<0.01). CONCLUSIONS: The efficacy of risperidone is comparable to that of haloperidol. The prevalence of EPS of risperidone in recommended dose range is significantly lower than that of haloperidol.

目的:对比利培酮与氟哌啶醇治疗精神分裂症的疗效和安全性。方法:101例精神分裂症患者随机分为两组,采用平行双盲随机对照方法分别口服利培酮2~6mg·d-1(51例)或氟哌啶醇6~18mg·d-1(50例)治疗,疗程6周。采用阳性和阴性症状量表(PANSS)和临床疗效四级评定标准评定疗效。用Simpson—Angus量表(SAS)和治疗中出现的药物不良反应量表(TESS)评定不良反应。结果:利培酮和氟哌啶醇的临床总有效率分别是68.6%和60.0%(P>0.05)。两药对精神分裂症阳性,阴性症状及一般精神病理学症状均有良好疗效,但两组间各种疗效指标无显著差异。利培酮的锥体外系症状(EPS)严重度显著低于氟哌啶醇。在肌紧张,震颤,静坐不能三种药物不良反应的严重度,TESS总严重度,药物不良反应所致痛苦程度诸方面,利培酮也显著低于氟哌啶醇(P<0.01)。结论:利培酮与氟哌啶醇总体疗效相当;临床治疗剂量的利培酮所致的EPS显著低于氟哌啶醇。

 
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