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治疗剂量
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  therapeutic dose
     The average initial dose of risperidone was (0.72±0.26) mg·d-1 , po, the average therapeutic dose, (1. 58 ± 0. 83) mg· d-1 , po.
     利培酮的平均起始剂量为(0.72±0.26)mg·d-1,平均治疗剂量(1.58±0.83)mg·d-1。
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     therapeutic dose As 2O 3 (1mg/kg.d and 2mg/kg.d) didn't damage the brain, liver and kidney of mouse.
     治疗剂量 (1mg/kg .d和 2mg/kg .d)的砷剂对小鼠脑、肝、肾等重要脏器未造成明显损害。
短句来源
     Methods:36 intravenous injections were prepared by dissolving the therapeutic dose into 0.9% sodium chloride injection or 5% glucose injection,then the particulates in size 1,2, 3,5,8,10 ,20,and 25μm were counted with HIAC Royco Coulter counter and the character of particulates were identified by microscopy.
     方法:将36种注射剂按治疗剂量(其中24种溶配于0.9%氯化钠注射液或5%葡萄糖注射液中,12种输液直接测试),用HIAC Royco 8 000A仪计数该液中直径≥1,2,3,5,8,10,20,25μm的微粒数;
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     RESULTS: TUR of tracer 131 I dose was lower than that of therapeutic dose using thyroid function instrument at 4, 6, 24 h ( F=53.64, P <0.01).
     结果 :用甲状腺功能仪方法测出的甲状腺摄13 1I率示踪剂量均低于治疗剂量 (P <0 .0 1) ,两种方法之间存在统计学差异 (F =5 3.6 4 ,P <0 .0 1) ;
短句来源
     Methods: 23 anti-infective intravenous injections were prepared by dissolving the therapeutic dose into O. 9%sodium chloride injection or 5% glucose injection, then the particulates in slze 1、2、3、5、8、10、20and 25μm were counted with HIAC Royco Coulter counter and the character of particulates were identified by microscopy.
     方法:将23种注射剂按治疗剂量(其中22个药品溶配于0.9%氯化钠注射液或5%葡萄糖注射液中,6个药液装量≥100mL药品直接测试),用HIAC Royco 8000A仪计数该液中直径≥1、2、3、5、8、10、20和25μm的微粒数;
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  “治疗剂量(”译为未确定词的双语例句
     Results:The average dosage of fluvoxamine was (108±20)mg/d,marked efficacy rate was 61.8%,response rate was 94.1%.
     结果:氟伏沙明平均治疗剂量(108±20)mg/d,显效率61.8%,有效率94.1%。
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     Results:For all elderly patients,the average initial dosage was (1.28±0.63)mg/d,the average therapeutic dosage was (2.90±1.24)mg/d,the total efficacious rate was 86.2%, the incidence of EPS was 31.0%.
     结果 :老年病人的平均起始剂量为 (1.2 8± 0 .6 3) m g/ d,平均治疗剂量 (2 .90± 1.2 4) m g/ d,总有效率 86 .2 % ,锥体外系反应发生率31.0 %。
短句来源
     Results: The average initial dosage was (5.46±3.36) mg and the average therapeutic dosage was (10.11±4.58)mg. The total efficacious rate was 58.73%.
     结果 :平均起始剂量 ( 5 .4 6± 3.36 ) mg,平均治疗剂量 ( 10 .11± 4 .5 8) mg,总有效率 5 8.73%。
短句来源
     d -1 then gradually been added to therapying dose(3~6mg.d -1 ),all patients were evaluated after 12 weeks.
     d- 1开始 ,逐渐增加到治疗剂量 (3~ 6mg.d- 1 ) ,疗程 1 2周。
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     METHODS The new Zealand white rabbits of two groups were given 150μg·kg~(-1) and 5μg·kg~(-1) bw of clenbuterol by ig administration respectively. The concentrations of clenbuterol in plasma were determined by ELISA at given times after administration.
     方法新西兰兔单剂量灌胃(ig)中毒剂量(150μg·kg-1)与治疗剂量(5μg·kg-1)的盐酸克仑特罗溶液,采用酶标免疫分析(ELISA)测定不同时间的血浆药物浓度。
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  相似匹配句对
     Effects of high does intravenous immunoglobulin for treatment of idiopathic thrombopenic purpura
     大剂量丙种球蛋白治疗特发性血小板减少性紫癜
短句来源
     High-Dose Methotrexate in Treatment of Acute Lymphoblastic Leukemia
     大剂量甲氨蝶呤治疗急性淋巴细胞白血病
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     (3) long-term small-dosage anticoagulant therapy;
     (3)长期小剂量抗凝治疗;
短句来源
     Comparative study of low dose~(131)I treatment in patients with Graves'disease
     小剂量~(131)I治疗甲亢的对比研究
短句来源
     The Therapeutic Effect of Different Dose~(131)I on Hyperthroidism
     不同剂量~(131)I治疗甲状腺机能亢进症疗效观察
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  therapeutic dose
In conclusion, some oxidative changes provoked in the testis of rabbits by hyperglycemia, were found to be reduced with repaglinide treatment at therapeutic dose.
      
These results suggest that administration of indomethacin in a maximal single therapeutic dose, does not affect the sympathetic nervous system or circulatory responsiveness to cold pressor testing.
      
The therapeutic dose range for all clinical outcome measures in adults is 100 to 1000 ?g/d of beclomethasone dipropionate or budesonide, or 50 to 500 ?g/d of fluticasone propionate.
      
However, questions remain unanswered, including optimal therapeutic dose.
      
Low-dose I-2190A could potentiate the effect of sub-therapeutic dose of CsA as well.
      
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(1)The present communication is a continuation of previous study of drugs on the pathologico-physiological reactions of the infected rabbits.The following indices of the reactions were used,namely:(1) erythrocyte sedimentation rate (ESR),(2) plasma fibrinogen content,(3) plasma gamma globulin content,(4) prothrombin time and (5)body weight. (2)It was shown that a full course of potassium antimony tartrate (PAT) could depress the abnormal rise of ESR of the infected rabbit.The effect was more striking in the...

(1)The present communication is a continuation of previous study of drugs on the pathologico-physiological reactions of the infected rabbits.The following indices of the reactions were used,namely:(1) erythrocyte sedimentation rate (ESR),(2) plasma fibrinogen content,(3) plasma gamma globulin content,(4) prothrombin time and (5)body weight. (2)It was shown that a full course of potassium antimony tartrate (PAT) could depress the abnormal rise of ESR of the infected rabbit.The effect was more striking in the early (i.e.7th day after inoculation) than the late treatment (i.e.33rd day after inoculation).This effect of PAT on the ESR was found to be in parallelism with its therapeutic effect.This method may be utilized for evaluation of drugs against schistosomiasis. (3)Neither PAT nor strychnine had any effect on the ESR of the normal rabbit.Strychnine was also found to have no significant effect on the ESR of the infected rabbit,but it could markedly modify the inhibitory effect of the PAT. (4)The therapeutic effect of half-course of PAT was found to be about 10—20% less marked than that of combined treatment with strychnine. Strychnine alone did not show any therapeutic effect.It was also found that the dose of strychnine used in our experiment did not increase the toxicity of PAT as shown by mice toxicity test. (5)The therapeutic dose of PAT showed no effect on the plasma fibrinogen content of the normal rabbit but it could bring the increased plasma fibrinogen content back to normal in the infected animal. (6)After a course of PAT in the infected animal,the double peak rise of the palsma gamma globulin content was distinctly suppressed as compared with the control group.On the contrary,the new drug,1:7-Bis (p-dimethylaminophenoxy) heptane (APH) did not show the same effect, probably indicating its weak action against schistosomiasis. (7)The body weight of the PAT treated group was found to be much higher than the non-treated group,However,the group treated with APH showed a continuous drop of body weight. (8)It has been found,as by others,that the APH showed high toxicity and low therapeutic effect in the experimental animals.From the fact that APH showed pronounced effect on ESR and plasma fibrinogen content of the infected animal,one could not yet decide,with the available data,whether these effects are due to its action on the schistosome or its eggs,or to its toxic action on the host.

(一)本文报告了药物对于血吸虫病病兔及正常家兔的红血球沉降率,血浆纤维蛋白,丙种球蛋白,凝血酶元时值及体重的影响。(二)酒石酸锑钾的治疗,无论在家兔患病的早期或后期,均可抑制其血沉的加速,而以早期治疗的抑制作用更为显著。同时这个抑制血沉的作用与治疗后的成虫发育率是符合的。因此利用这种方法,可以考虑作为研究一些治疗血吸虫病药物的疗效指标。(三)酒石酸锑钾及士的宁本身对正常家兔的血沉并不引起改变,士的宁对于病兔的血沉也无明显作用,但士的宁可以影响酒石酸锑钾对病兔血沉的抑制作用。 (四)半疗程剂量酒石酸锑钾并用士的宁之疗效较单独应用半疗程剂量酒石酸锑钾者为高(10—20%),而单独应用士的宁并无任何疗效,轻度激动量士的宁也不增加酒石酸锑钾的毒性。(五)酒石酸锑钾的治疗剂量对于正常家兔之血浆纤维蛋白元无明显影响,但能使病兔增高之血浆纤维蛋白元回复正常。(六)酒石酸锑钾的治疗可以使病兔的丙种球蛋白在一定时期内保持在接近正常值范围内,这一抑制作用与感染对照组相比,甚为明显,而氨苯氧烷却无此作用,这一点可能与疗效是有关系的。(七)酒石酸锑钾治疗后的病兔之体重较感染对照组病兔显著增高,而经氨苯氧烷治疗后之病兔,其...

(一)本文报告了药物对于血吸虫病病兔及正常家兔的红血球沉降率,血浆纤维蛋白,丙种球蛋白,凝血酶元时值及体重的影响。(二)酒石酸锑钾的治疗,无论在家兔患病的早期或后期,均可抑制其血沉的加速,而以早期治疗的抑制作用更为显著。同时这个抑制血沉的作用与治疗后的成虫发育率是符合的。因此利用这种方法,可以考虑作为研究一些治疗血吸虫病药物的疗效指标。(三)酒石酸锑钾及士的宁本身对正常家兔的血沉并不引起改变,士的宁对于病兔的血沉也无明显作用,但士的宁可以影响酒石酸锑钾对病兔血沉的抑制作用。 (四)半疗程剂量酒石酸锑钾并用士的宁之疗效较单独应用半疗程剂量酒石酸锑钾者为高(10—20%),而单独应用士的宁并无任何疗效,轻度激动量士的宁也不增加酒石酸锑钾的毒性。(五)酒石酸锑钾的治疗剂量对于正常家兔之血浆纤维蛋白元无明显影响,但能使病兔增高之血浆纤维蛋白元回复正常。(六)酒石酸锑钾的治疗可以使病兔的丙种球蛋白在一定时期内保持在接近正常值范围内,这一抑制作用与感染对照组相比,甚为明显,而氨苯氧烷却无此作用,这一点可能与疗效是有关系的。(七)酒石酸锑钾治疗后的病兔之体重较感染对照组病兔显著增高,而经氨苯氧烷治疗后之病兔,其体重仍日见减轻。(八)氨苯氧烷有较高的毒性,但疗效甚低,它对病兔的血沉及纤维蛋白元所出现的抑制作用,究竟属于对血吸虫或其虫卵的作用,抑系对于病兔机体的毒性作用,目前还不能肯定。

On the dog heart-lung preparations,therapeu- tic doses of potassium antimony tartrate could produce a definite cardio-inhibitory effect,as shown by a rise of the left auricular pressure and venous pressure,along with a slight drop in the arterial pressure.The pulmonary arterial pressure rose also in many cases,particularly when the pH of the injected drug solution was raised to 7.Also observable were some dilatation of the heart, some slowing of its beat and some diminution of the minute volume.Ventricular fibrillation...

On the dog heart-lung preparations,therapeu- tic doses of potassium antimony tartrate could produce a definite cardio-inhibitory effect,as shown by a rise of the left auricular pressure and venous pressure,along with a slight drop in the arterial pressure.The pulmonary arterial pressure rose also in many cases,particularly when the pH of the injected drug solution was raised to 7.Also observable were some dilatation of the heart, some slowing of its beat and some diminution of the minute volume.Ventricular fibrillation was produced repeatedly in one preparation by small doses of adrenaline given after the antimony com. pound.

对于犬心肺装置,治疗剂量的酒石酸锑钾可产生明显的心臓抑制作用,此种抑制可表现为:左心房压的显著升高,腔静脉压的升高与动脉压的轻微低降。肺动脉压的升高,在注射 pH 7的酒石酸锑钾溶液后特别显著。同时也可观察到心臓的扩张,心率的变慢与心输出量的减少。在锑剂作用后,小剂量肾上腺素产生心室颤动。此种现象曾在一犬反复出现多次,值得作进一步研究。

Mice inoculated with Ehrlich ascites carcinoma cells were intraperitoneally injected on the 8th day with actinomycin K. The animals were killed 6 hours after injection.

小白鼠接种Ehrlich腹水癌細胞后第8天,腹腔注射生理盐水(对照組)或放线菌素K,6小时后解剖,研究放綫菌素K对癌細胞核酸等含量的影响。当放綫菌素K的剂量为50微克/公斤体重(治疗剂量)时,6小时后每毫克干重癌細胞中酸溶磷、脂溶磷、RNA和DNA的含量都沒有变化。增高剂量为400微克/公斤时,每毫克干重癌細胞中酸溶磷、无机磷、脂溶磷、核蛋白氮以及DNA的含量仍沒有明显改变,但RNA含量則降低。以細胞为单位作比較,結果也一致。若于接种后第3天开始給药,剂量为50微克/公斤/天,共5天,停药后6小时解剖。每单位細胞的干重稍有減低,但經t测驗比較,相差不显著。每单位癌細胞中酸溶磷、脂溶磷和DNA沒有明显影响,RNA則下降更甚而核蛋白氮也开始減少。若以干重为单位比較,RNA仍有很大降低,核蛋白氮相差不明显而DNA反有显著升高。于一次注射药物后2小时,皮下注射Na_2HP~(32)O_41微居里/克体重,再隔4小时后解剖,比較对照組和給药組癌細胞中酸溶磷、无机磷和RNA的比放射強度(脉冲数/分钟/微克磷)。发現給药組酸溶磷和无机磷的比放射強度,不論剂量为50或400微克/公斤,都不变。RNA的比放射強度則...

小白鼠接种Ehrlich腹水癌細胞后第8天,腹腔注射生理盐水(对照組)或放线菌素K,6小时后解剖,研究放綫菌素K对癌細胞核酸等含量的影响。当放綫菌素K的剂量为50微克/公斤体重(治疗剂量)时,6小时后每毫克干重癌細胞中酸溶磷、脂溶磷、RNA和DNA的含量都沒有变化。增高剂量为400微克/公斤时,每毫克干重癌細胞中酸溶磷、无机磷、脂溶磷、核蛋白氮以及DNA的含量仍沒有明显改变,但RNA含量則降低。以細胞为单位作比較,結果也一致。若于接种后第3天开始給药,剂量为50微克/公斤/天,共5天,停药后6小时解剖。每单位細胞的干重稍有減低,但經t测驗比較,相差不显著。每单位癌細胞中酸溶磷、脂溶磷和DNA沒有明显影响,RNA則下降更甚而核蛋白氮也开始減少。若以干重为单位比較,RNA仍有很大降低,核蛋白氮相差不明显而DNA反有显著升高。于一次注射药物后2小时,皮下注射Na_2HP~(32)O_41微居里/克体重,再隔4小时后解剖,比較对照組和給药組癌細胞中酸溶磷、无机磷和RNA的比放射強度(脉冲数/分钟/微克磷)。发現給药組酸溶磷和无机磷的比放射強度,不論剂量为50或400微克/公斤,都不变。RNA的比放射強度則下降:50微克/公斤組降低40%,400微克/公斤組降低52%。

 
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