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In order to dermine the effect of peenteral nutrition (PN), dexamethson (DM) and theircombination(PN+DM) on lung cancer. Thirty six nude mice bearing human adenocarcinoma of thelung cameinto ewperiments. The alterations of DNA synthesis phase in tumor cells were detected withFCM method. the 24hr of administration, percentage of S phase cells (S%) were53. 4± 10. 2,46. 5± 9. 1,and 59. 8±8. 0 for PN,DM and PN+DM respectively. In the control group it was 44. 7± 8. 1. After 48hr,S% in the above three groups were... In order to dermine the effect of peenteral nutrition (PN), dexamethson (DM) and theircombination(PN+DM) on lung cancer. Thirty six nude mice bearing human adenocarcinoma of thelung cameinto ewperiments. The alterations of DNA synthesis phase in tumor cells were detected withFCM method. the 24hr of administration, percentage of S phase cells (S%) were53. 4± 10. 2,46. 5± 9. 1,and 59. 8±8. 0 for PN,DM and PN+DM respectively. In the control group it was 44. 7± 8. 1. After 48hr,S% in the above three groups were 36. 4± 4. 8' 39. 9± 6. 6,and 46, 6± 6. 9,respectively. In the control group it was 44. 4±8. 8. The results showed that S% in PN+DM groupat 24hr was increased significantly(P<0. 05) compeing with thase in the control group and suggestedthat the PN+DM combination at 24hr post-administration might have synergistic effect on the ratioof tumor cells at S phase,This alterated cytokinetics might influence the chemosensitivity of tumorcells to cycle-specific agents. 采用胃肠外营养（PN）、地塞米松（DM）及PN＋DM对36只人肺腺癌裸鼠模型LAX－83肿瘤细胞中中期细胞百分率（S％）的影响，PN组予12．54kJ／kg-1·d-1＋氮量0．2g／kg－1·d-1，DM组予20μg／d，对照组予生理盐水，分2次早晚腹腔注射，用FCM测定S％，结果，24h，PN＋DM组的S％增加最大，显著高于对照组，提示PN＋DM的联合作用。24h后对S％增加有协同作用。 Objective: To study the inducible expression of hepatitis C virus ns3 gene (HCV ns3) in eukaryotic cells. Methods: The ns3 gene was obtained from plasmid pBns3 by polymerase chain reaction and inserted into the cloning vector pGEMT. Then, the ns3 was subcloned into the vector pMSG to generate dexamethasone (DM)inducible expression plasmid pMSGns3. CHO cells were transfected by pMSGns3 by using calcium phosphate precipitated method and cultivated for 12 to 24 h.The transfected cells were induced... Objective: To study the inducible expression of hepatitis C virus ns3 gene (HCV ns3) in eukaryotic cells. Methods: The ns3 gene was obtained from plasmid pBns3 by polymerase chain reaction and inserted into the cloning vector pGEMT. Then, the ns3 was subcloned into the vector pMSG to generate dexamethasone (DM)inducible expression plasmid pMSGns3. CHO cells were transfected by pMSGns3 by using calcium phosphate precipitated method and cultivated for 12 to 24 h.The transfected cells were induced with DM and the transient expression of NS3 protein was analyzed by using ELISA and Westernblot methods. Results: After treatment with 3×10~(-8) mol/L DM,the expression of NS3 was observed in the transfected CHO cells. A slightly higher level of NS3 was shown with the delay time of DM treatment. Conclusion: The inducible expressing vector pMSGns3 might be helpful for further studies of the characterizations of the ns3 gene in vivo. 目的：研究丙肝病毒非结构蛋白基因３（ｎｓ３基因）在体外真核细胞中的诱导表达。方法：以ＰＣＲ方法从含ＨＣＶｎｓ３基因的重组载体ｐＢｎｓ３中扩增出ｎｓ３基因，并将其插入到克隆载体ｐＧＥＭ－Ｔ中，再与表达载体ｐＭＳＧ重组，以得到重组表达载体ｐＭＳＧ－ｎｓ３。然后采用磷酸钙沉淀法将其转染哺乳动物ＣＨＯ细胞，经地塞米松（ＤＭ）诱导，采用ＥＬＩＳＡ及Ｗｅｓｔｅｒｎ－ｂｌｏｔ技术检测ＮＳ３蛋白的表达水平。结果：用所构建的诱导型表达载体ｐＭＳＧ－ｎｓ３转染ＣＨＯ细胞，经ＤＭ（３×１０－８ｍｏｌ／Ｌ）诱导后可表达ＮＳ３蛋白，其浓度与时间呈正相关。结论：所得到的表达载体在培养细胞中能够有效地表达，为下一步研究丙肝病毒ｎｓ３基因在活体内的生物学特性准备了条件 Objective: 目的：研究哮喘时嗜酸性粒细胞（Ｅｏｓ）凋亡与Ｆａｓ表达的关系及药物对它们的影响。方法：应用地塞米松（ＤＭ）、雷公藤甲素（Ｔｒｉｐｔｏｌｉｄｅ，ＴＰ）及氨茶碱（ＡＭ）干预哮喘豚鼠，以ＴＵＮＥＬ法检测细胞凋亡，以ＲＴ－ＰＣＲ及原位杂交检测ＦａｓｍＲＮＡ表达。结果：哮喘组Ｅｏｓ凋亡率较正常对照组显著降低（Ｐ＜０．０１），应用ＤＭ、ＴＰ、ＡＭ后均显著增加（Ｐ＜０．０１）。正常豚鼠Ｅｏｓ可检测到ＦａｓｍＲＮＡ表达，不同密度Ｅｏｓ表达差异不显著（Ｐ＞０．０５）。哮喘组ＦａｓｍＲＮＡ明显减少，以低密度Ｅｏｓ减少明显（Ｐ＜０．０５），应用ＤＭ、ＴＰ、ＡＭ后其表达明显增加。结论：凋亡调节的缺失是导致组织及血中Ｅｏｓ增多的重要原因，Ｆａｓ抗原参与了哮喘Ｅｏｓ凋亡的调节，低密度Ｅｏｓ更能反映哮喘的特征。ＤＭ、ＴＰ、ＡＭ可促进哮喘肺组织中的Ｅｏｓ表达Ｆａｓ抗原，进而加强细胞凋亡。
地塞米松dm
“地塞米松（dm）”译为未确定词的双语例句
The transfected cells were induced with DM and the transient expression of NS3 protein was analyzed by using ELISA and Westernblot methods. 然后采用磷酸钙沉淀法将其转染哺乳动物CHO细胞，经地塞米松（DM）诱导，采用ELISA及Western－blot技术检测NS3蛋白的表达水平。 短句来源 Objective:To observe the changes of tumor necrosis factorα(TNFα) and interleukin6(IL6) released by alveolar macrophages (AM) and the effect of dexamethasone (DM) on TNFα and IL6 levels in bleomycininduced lung injury in rats. 目的：观察博莱霉素（BLM）诱发大鼠肺损伤后肺泡巨噬细胞（AM）释放肿瘤坏死因子 α（TNF α）和白细胞介素 6（IL 6）的变化及地塞米松（DM）对AM 释放TNF α和IL 6的影响。 短句来源 AIM To investigate the effects of dexamethasone (DM) and glycyrrhizin (GL) on the hepatocyte apoptosis caused by phenobarbital (PB) withdrawal in mice. 目的研究地塞米松（DM）及甘草酸（GL）对小鼠肝细胞凋亡的影响。 短句来源 Aim To investigate the effect of dexamethasone ( DM) on expression of bcl-2 mRNA and apoptosis of eosinophils( Eos) in bronchoalveolar lavage fluid ( BALF) from asthmatic guinea pig, and mechanism of Eos apoptosis promoted by steroid. 目的观察地塞米松（DM）对哮喘豚鼠体外不同密度的嗜酸性粒细胞（Eos）凋亡及bc－2表达的影响，并探讨激素促进哮喘EOS凋亡的机制。 短句来源 相似匹配句对
dm? dm? 短句来源 AIM To investigate the effects of dexamethasone (DM) and glycyrrhizin (GL) on the hepatocyte apoptosis caused by phenobarbital (PB) withdrawal in mice. 目的研究地塞米松（DM）及甘草酸（GL）对小鼠肝细胞凋亡的影响。 短句来源 Tragicomical DM 悲喜DM 短句来源 HPLC determination for dissolution of dexamethasone tablets 地塞米松片的溶出度 短句来源 Objective: To investigate the effects of desamethasone (DM) and triptolide (TP) on apoptosis of CD4 and CD8T cells in asthma. 目的 :探讨地塞米松(DM)和雷公藤对哮喘CD4、CD8细胞凋亡的作用。 短句来源 
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An experimental model for pulmonary toxicity of KW-2149, a new mitomycin C analogue, was established and the inhibitory effects of dexamethasone (DM) were investigated.
Dexamethasone (DM) resistance was evaluated in fibroblasts from a pool of five patients with cystic fibrosis (CF) homozygotes, ten of their parental obligate heterozygotes, and seventeen age-matched controls of both sexes.
The steroids used were cortisone (CA), betamethasome (BM), and, in the prenatal group only, dexamethasone (DM).
Two of the animals were injected with dexamethasone (DM) and then challenged.
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