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dm大鼠
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  dm rats
     (3) Compared with model group, HZT 220 mg/kg and 440 mg/kg decreased the T2DM rats'FBG and TC (P<0.05);
     (3)与模型对照组比较,220mg/kg和440mg/kg HZT能降低T2DM大鼠FBG和TC,差异具有统计学意义(P<0.05);
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     (2)DM rats were divided into 3 groups randomly: group GHRH analog was treated with Pro-Pro-hGHRH(1-44) OH 1 mg·L~(-1) intraperitoneally,Group GHRH treated with hGHRH 2()mg·L~(-1) intraperitoneally,group DM control treated with 0.9% NS.
     (2)将DM大鼠随机分为GHRH类似物组、GHRH组和DM对照组,分别给予Pro-Pro-hGHRH(1-44)OH 1 mg. L-1、hGHRH(1-44)OH 2 mg.
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     Results The expression of CD14 on AM surface and the levels of TNF-α and IL-6 in serum in T2DM rats without LPS challenge were significantly higher than those in normal control rats(P<0.05).
     结果T2DM大鼠AM表面CD14表达和血清TNFα-、IL-6水平明显高于正常对照大鼠(P<0.05)。
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     CONCLUSION: The NGF and NF contents in hippocampus of T2DM rats are decreased, and HPD mixture can increase the expressions of NGF and NF in hippocampus of T2DM rats.
     结论:T2DM大鼠脑海马NGF、NF含量下降,翻白草合剂可增加T2DM大鼠脑海马NGF、NF的表达。
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     Conclusion Na~+,K~+-ATPase activity of PT in T2DM rats is increased and EDLS level in serum decrease may play a important role.
     结论T2DM大鼠PT的Na~+,K~+-ATPase活性升高,这种酶活性升高与血液中EDLS水平下降有关。
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  dm rat
     4. The blood sugar and serum AGE level of DM rat were significant higher than control (P<0.01).
     4. DM大鼠血糖和血清AGE含量明显高于正常对照组(P<0.01)。
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     Furthermore,the ΔI30/ΔG30 and MBCI increased obviously than those in DH group(P<0.01、P<0.05). Conclusion High fat diet can cause TG and FFA ectopicly accumulate in the islets of T2DM rat and then decrease the secretion of insulin.
     胰岛素治疗后,与DH组相比,胰腺内TG和FFA计量明显下降(分别为P<0·01、P<0·01),同时ΔI30/ΔG30、MCBI均得到明显改善(P<0·01、P<0·05)结论长期高脂饮食喂养可导致T2DM大鼠胰腺内FFA和TG沉积,并进一步损伤胰岛B细胞胰岛素的分泌;
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     Conclusion In DM rat brain,the activation of GSK-3 leads to overexpression of Aβ,and Li_2CO_3 might reduce the expression of Aβ by inhibiting GSK-3.
     结论DM大鼠海马GSK-3的活性异常增加,可能诱导Aβ的表达增加。
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     3. Observ DM rat for three months and re-analyze the related factors such as oxygen-derived free radical, apoptosis and regeneration in the group with blood sugar<7.8, the group with blood sugar>1.2 and insulin treatment group.
     3、DM大鼠的3个月的观察及血糖小于7.8组、血糖大于11.1组和胰岛素治疗组胰岛氧化自由基、凋亡、再生相关因子的再分析。
短句来源
     Results In the hippocampus of the diabetic brain, IGF IRα, Akt/PKB and CREB involved in the insulin transduction pathway were decreased, while GSK 3β, PP 1, Bax and AIF related to apoptosis signal transduction pathway were increased. In addition, the hippocampal neurons of the DM rat showed degenerative changes.
     结果  DM大鼠 IGF- IRα、Akt/ PKB、CREB表达明显降低 ,APP17肽治疗后明显上调 (P <0 .0 5 ) ,GSK- 3β、PP- 1及凋亡相关蛋白 Bax、AIF表达增加 ,治疗后则明显降低 (P <0 .0 5 ) ;
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  “dm大鼠”译为未确定词的双语例句
     Results Compared with the controls, serum NO in STZ DM group significantly elevated 〔(51.3±11.9 vs 38.1±12.0)μmol/L, P<0.01〕.
     结果 STZ DM大鼠与正常对照组相比 ,血清NO水平显著升高〔(5 1.3± 11.9vs 38.1± 12 .0 )μmol/L ,P <0 .0 1〕 ;
短句来源
     (2)The whole blood viscosity(44.86±9.15) and plasma viscosity(1.45±0.12) in DC were significantly higher than NC(P<0.05).
     (2)DM大鼠的全血粘度(44.86±9.15)、血浆粘度(1.45±0.12)均显著高于正常大鼠(P<0.05)。
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     Methods To establish immediate streptozotocin (STZ)-DM model rats using intraperitoneal injection one time with the dose of 60 mg/kg, then determined the levels of plasma ET-1, PGE_2, TXB_2 and 6-Keto-PGF_ 1α of the model rats and observed the pathology of the femoral head.
     方法SD大鼠腹腔内注射链脲佐菌素(STZ)60mg/kg建立速发型STZDM模型,测定DM大鼠及对照大鼠血浆ET1、PGE2、TXB2及6KetoPGF1α水平,观察股骨头病理学变化。
短句来源
     Rats from DM group and Tau group were given 50 mg/kg streptozotocin(STZ) by intraperitoneal injection.
     DM组和Tau组腹腔注射链脲菌素(STZ)50mg/kg复制DM大鼠模型。
短句来源
     CTGF mRNA expression in the renal cortex of DM group was (2.65 times) that of CON group,and the expression of DM+B group was lower by 23.68% compared with that of DM group.
     DM大鼠肾皮质CTGF mRNA表达水平约为CON组的2.65倍(P<0.01),在DM+B组其表达水平减少23.68%(P<0.05)。
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  dm rats
Aquaporin 2 (AQP2) was not increased in the inner medullas of 10-day DM rats either.
      
We investigated the effects of intermittent administration of h-PTH on bone changes in streptozotocin- (STZ-) induced diabetes mellitus (DM) rats by measuring bone mineral density and bone mineral contents and by bone histomorphometry.
      
Immunofluorescence staining for ICAM-1 in the glo merulus of DM rats.
      
Rat aortic -catalytic isoforms abundance in C and DM rats.
      
RSV significantly decreased insulin secretion and delayed the onset of insulin resistance in STZ-nicotinamide DM rats.
      
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  dm rat
Isolated streptozotocin-induced 6-week DM and non-DM rat hearts with a balloon in the left ventricle (LV) were paced and normal perfused at 75 cm H2O with normoxic Krebs-Henseleit solution.
      
Regional defects in the expression and/or electrophysiology of SAN ion channels, and in particular those involved in AP repolarization, might underlie heart rhythm disturbances in the STZ-induced DM rat.
      
In the DM rat model, cardiac function deteriorated in proportion to the duration of diabetes.
      
We identified a germ line DMR at which methylation is acquired in oocytes and maintained after fertilization.
      


Ultrastructue of the aortic wall in rats with diabetes induced by STZ is studied.The radioimmunologic and biochemical data obtained show a significant decrease in plasma insulin level and a significant increase in blood glucose content in diabetic as compared with the normal rats (P<0.01).TC, LDL-C, LDL-C/HDL-C and TC/HDL-C are increased, but HDL-C is significantly de-creased in diabetic rats.Under SEM and TEM, early atherosclerotic ohanges are found in the aortic wall of diabetic rats.The results show that,in...

Ultrastructue of the aortic wall in rats with diabetes induced by STZ is studied.The radioimmunologic and biochemical data obtained show a significant decrease in plasma insulin level and a significant increase in blood glucose content in diabetic as compared with the normal rats (P<0.01).TC, LDL-C, LDL-C/HDL-C and TC/HDL-C are increased, but HDL-C is significantly de-creased in diabetic rats.Under SEM and TEM, early atherosclerotic ohanges are found in the aortic wall of diabetic rats.The results show that,in acute exper-imental diabetes, hyperglycemia, hypercbolesterolemia, hyperlipemia of LDL-C and hypolipemia of HDL-C resulted from absolute hypoinsulinism may be close-ly related to the formation of early aortic atherosclerotic changes.

本实验对STZ—DM大鼠的主动脉进行了超微结构观察。结果显示,DM大鼠血浆胰岛素水平明显降低,血糖含量明显增高、血浆TC、LDL—C、LDL—C/HDL—C、TC/HDL-C值明显增高,HDL—C明显降低,与对照组比较均有显著差异(P<0.01)。电镜下,DM大鼠主动脉有早期AS病变。结果表明,急性实验性DM,由胰岛素绝对缺乏所致的高血糖、高TC、高LDL—C以及低HDL—C血症,可能与主动脉早期AS病变的形成密切相关。

The experiment is about insulin (INS) treatment of streptozotocin (STZ) induced diabetes in rats. Early atherosclerotic (AS) changes in the aorta are observed in normal diet DM rats (control group) and INS-eated group (experimental group) morphologically. The results suggested that serum INS level in the experimental group was approaching that of the control group, but the vasculopathy is more severe in the experimental group than in the DM group. This indicates that the effect of INS on the arterial wall is...

The experiment is about insulin (INS) treatment of streptozotocin (STZ) induced diabetes in rats. Early atherosclerotic (AS) changes in the aorta are observed in normal diet DM rats (control group) and INS-eated group (experimental group) morphologically. The results suggested that serum INS level in the experimental group was approaching that of the control group, but the vasculopathy is more severe in the experimental group than in the DM group. This indicates that the effect of INS on the arterial wall is advantageous to the formation of DM-AS.

本实验用INS治疗STZ-DM大鼠,主要通过形态现察对比在正常饮食条件下DM状态和用INS治疗后主动脉早期AS病变。结果显示治疗组动物血清INS水平接近对照组,但血管病变却明显重于DM组。结果表明INS对动脉壁的影响有促进发生AS的作用。

In this study, we treated SD rats with Streptozotocin(STZ) to induce diabetic rats. Aftar 12 weeks, the diabetic rats were given gliclazide or gliolazide and E itrendipine respectively by gavage for ten days, and the effects of gliclazide and nitrendipine on glucose, lipid metabolism and B-cell function were observed. Plasma insulin immediately before and 1, 2, 3 hours after glucose stimulation, sorum cholesterol, highdensity lipoprotein, triglyceride, and insulin level after pancreatic tissue culture were not...

In this study, we treated SD rats with Streptozotocin(STZ) to induce diabetic rats. Aftar 12 weeks, the diabetic rats were given gliclazide or gliolazide and E itrendipine respectively by gavage for ten days, and the effects of gliclazide and nitrendipine on glucose, lipid metabolism and B-cell function were observed. Plasma insulin immediately before and 1, 2, 3 hours after glucose stimulation, sorum cholesterol, highdensity lipoprotein, triglyceride, and insulin level after pancreatic tissue culture were not different between the two groups (P>0.05), but the blood glucose before and 1, 2, 3 hours after glucose loading, serum fruetosamine, B-lipoprotein were significantly different (P<0.05). The urin& glucose levels also significantly different (P<0.01) via Eidit analysis. The preliminary data suggested that qliclazide has a hypoglyoemic effect in STZ-DM rats by increasing insulin sensitivity in peripheral target tissues while nitrendipin affects significantly the glucose metabolism attenuating the hypoglycemic effect of gliclazide in STZ diabatic rats.

本文以链脲佐菌素造成大鼠糖尿病,以甲磺吡脲和甲磺吡脲加尼群地平(NT)灌胃10d,观察NT和甲磺吡脲对糖、脂代谢及β-细胞功能的影响。结果为空腹及喂糖后1、2及3h血浆胰岛素、血脂及胰组织块孵育液和提取液中胰岛素水平与甲磺吡脲对照组比较无明显差别,而血清果糖胺、空腹咦糖后1、2及3h血糖与对照组有明显差别。资料表明:NT对链脲佐菌素-糖尿病(STZ-DM)大鼠糖代谢有明显影响,甲磺吡脲通过促进胰岛素在外周组织起降血糖作用。

 
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