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谷胱甘肽过氧化物酶gshpx
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  gsh peroxidase
     (3)Level of reduced glutathione(GSH)increased and level of GSH peroxidase decreased significantly in the pregnant rats and rat embryos treated with 0 2% and 0 5% lead acetate.
     ( 3)还原型谷胱甘肽 (GSH)含量在母鼠与胎鼠 0 0 5 %、0 2 %组显著增高 ,谷胱甘肽过氧化物酶 (GSH Px)含量则显著降低。
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  “谷胱甘肽过氧化物酶(gshpx”译为未确定词的双语例句
     The activities of blood GSH Px in quenching,welding and sealing groups were (71.42±26.52)NU/ml,(70.77±20.12)NU/ml and (71.67 ±18.87)NU/ml respectively,significantly lower than that in the control[(97.02±21.76)NU/ml, P <0.05 or P <0.01].
     焊接组、热合组和淬火组的谷胱甘肽过氧化物酶 (GSH Px)活力分别为 (71.42± 2 6 .5 2 )、(70 .77± 2 0 .12 )、(71.6 7± 18.87)NU/ml,明显低于对照组 ,差异有显著性 (P <0 .0 5 ) ;
短句来源
     the levels of serum creatine phosphokinase isoenzyme (CK-MB),myocardial malonaldehyole (MDA) 、superoxide dismutase (SOD)、glutathione peroxidase ( GSH-PX)、catalase (CAT)、Na + -K +-ATPase and Ca 2+-ATPase were detected at reperfusion 120 min.
     测定再灌注末血清磷酸肌酸激酶同工酶(CK MB),心肌丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH PX)、过氧化氢酶(CAT)、Na+K+ATP酶和Ca2+ATP酶的变化;
短句来源
     Method: 23month old SD rats are observed as naturally senile rate, of brainmitochondria membrane are conjugateddienes (CD), molondialdehyde (MDA), glutathione peroxidase (GSH Px), superoxide dismutase (SOD), Na + K + ATP ase and Ca 2+ Mg 2+ ATP ase measured as indexes to observe the effect of the PNPY.
     方法 :以 2 3月龄SD大鼠为自然衰老鼠 ,以脑线粒体膜共轭双烯 (CD)、丙二醛 (MDA)、谷胱甘肽过氧化物酶 (GSH Px)、超氧化物歧化酶 (SOD)、Na+ K+ ATP酶、Ca2 + Mg2 + ATP酶为主要指标 ,观察滋补脾阴方药的作用。
短句来源
     In the patients after treatment, blood lipid peroxide (LPO) dropped significantly(P<0.01) and superoxide dismutase (SOD) and glutathione peroxidase (GSH-P) rose significantly(P<0.01).
     治疗后,患者血过氧化脂质(LPO)显著下降(P<0. 01),而超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH Px)则明显升高(P<0. 01)。
短句来源
     The effects of different concentrations of selenium on the growth, the activities of superoxide dismutase(SOD), catalase(CAT), ascorbate peroxidase(APX), dehydroascorbate reductase(DHAR), glutathione peroxidase(GSH PX)and the content of ascorbate(AsA), hydrogen peroxide(H 2O 2)were studied in the hydroponic spinach.
     研究了不同浓度硒对菠菜的生长、超氧化物歧化酶 (SOD)、抗坏血酸过氧化物酶 (APX)、过氧化氢酶 (CAT)、脱氢抗坏血酸还原酶 (DHAR)、谷胱甘肽过氧化物酶 (GSH PX)等酶活性以及抗坏血酸(AsA)、过氧化氢 (H2 O2 )含量的影响。
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  相似匹配句对
     STUDY ON GLUTATHIONE PEROXIDASE
     谷胱甘肽过氧化物酶的研究
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     DETERMINATION OF GLUTATHIONE PEROXIDASE IN RICE SEEDLINGS
     水稻谷胱甘肽过氧化物酶的测定法
短句来源
     Study on Glutathione Peroxidese Activity in Yeast
     酵母中谷胱甘肽过氧化物酶(GSH-Px)活性的分析
短句来源
     Biosynthesis of Glutathione
     谷胱甘肽的生物合成
短句来源
     OBJECTIVE To clone the cDNA of human glutathione peroxidase 1(GPx1).
     目的 克隆中国人谷胱甘肽过氧化物酶 (GPx1)的cDNA。
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  gsh peroxidase
In brain, muscle, and blood, the activity of GSH peroxidase, a selenoenzyme, was decreased by Hg.
      
In liver, substantial accumulation of Hg with Se occured (molar Hg/Se ratio approximately 1.4 to 1.8) but GSH peroxidase activity was unaffected.
      
When 4 to 20 mg/L Se was added to the algal medium, this pathway was replaced by a so-called Sestressed pathway containing GSH peroxidase (GSH-POD).
      
SOD, catalase, GSH peroxidase) it is possible that the gut mucosa may be overwhelmed during times of active inflammation which could result in intestinal injury.
      
A high content of total glutathione and high activities of both GSH S-aryltransferase (CDNB) and GSH peroxidase were found in different segments of the human intestinal mucosa comparable to findings in human gastric mucosa.
      
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The purpose of the experiments is to study the effects of graded methionine levels in the diet on the biopotency of selenium in the 1 to 5—week-old White Plymouth Rock chicks and 1 to 6-week-old White Beijing Ⅲ Line chicks.A basal diet composed of maize, soybean and wheat supplemented with or without selenium as sodium selenite and/or DL—methionine was used. As evidenced by the parameters of growoth response, efficiency of feed utilization, glutathione peroxidase activity in blood and Selenium concentration...

The purpose of the experiments is to study the effects of graded methionine levels in the diet on the biopotency of selenium in the 1 to 5—week-old White Plymouth Rock chicks and 1 to 6-week-old White Beijing Ⅲ Line chicks.A basal diet composed of maize, soybean and wheat supplemented with or without selenium as sodium selenite and/or DL—methionine was used. As evidenced by the parameters of growoth response, efficiency of feed utilization, glutathione peroxidase activity in blood and Selenium concentration in tissues, the dietary methionine levels in chicks were found to affect the biopotency of selenite at dietary selenium levels of 0.1, 0.2 ppm, and altered the biopotency of selenium in the feed slightly. Under experimental conditions, methionine supplementation increased the biopotency of selenium. The optimum amount of seleium and methionine, including that in the feed and the supplementation, was 0.2 ppm selenium and 0.5 per cent of methionine.

用1日令—4周令白洛克雏鸡,1日令—6周令京Ⅲ系雏鸡,以玉米、黄豆、小麦等组成的饲粮,加或不加硒(Se,Na_2SeO_3)和(或)蛋氨酸(DL—Wet),测定了饲粮不同蛋氨酸水平对硒生物效能的影响。以体增重,料肉比,全血和血浆谷胱甘肽过氧化物酶(GSHPx)活力,组织硒含量等指标为判据,试验结果表明,在0.1,0.2ppm硒水平,雏鸡饲粮蛋氨酸水平影响亚硒酸钠硒的生物效能,对饲料硒的生物效能也有所影响。在本试验饲粮条件下,补加蛋氨酸提高硒的生物效能,而以硒0.2ppm和蛋氨酸0.5%的用量(饲料自身含量+添加量)为适宜配比。

Using the methods of cell culture and free radical biochemistry, we studied the levels of antioxidants and lipid peroxidation in an established baby hamster kidney fibroblast cell line (BHK-21/C13) and its polyonia virus-transformed counterpart (BHK-PyY). It was found that there were higher levels of reduced glutathione, selenium and glutathione peroxidase (GSH-Px) activity and a less MDA production in BHK-21/C13 cells than in BHK-21/PyY cells. There was no difference of glutathione S-transftrase and glutathione...

Using the methods of cell culture and free radical biochemistry, we studied the levels of antioxidants and lipid peroxidation in an established baby hamster kidney fibroblast cell line (BHK-21/C13) and its polyonia virus-transformed counterpart (BHK-PyY). It was found that there were higher levels of reduced glutathione, selenium and glutathione peroxidase (GSH-Px) activity and a less MDA production in BHK-21/C13 cells than in BHK-21/PyY cells. There was no difference of glutathione S-transftrase and glutathione reduetase activities between the two cell lines. Supplemented with α-tocopheroi in the medium, non-transformed cells took up more α-tocophe-rol than transformed cells. The content of glutathione, GSHPx activity, and α-tocopherol level decreased and MDA production increased in both cell lines stressed with iron, while the activities of glutathione transferase and glutathione reduetase remained unchanged. However, the relative increases and decreases except glutathione peroxidase, were found to be greater in BHK-21/C13 cells than in BHK-21/PyY ones. These results suggested that there were some differences in free radical metabolism between normal and malignant cells, at least between this two cell lines, and normal cells were more sensitive to peroxidative stimulation to a certain degree.

采用细胞培养及自由基生化方法,研究正常和过氧化条件下,幼年仓鼠肾成纤维细胞(BHK-21/C13)及其多瘤病毒转化株(BHK-21/PyY)的抗氧化物和脂质过氧化物水平,发现:非转化株的抗氧化物水平,除谷胱甘肽S-转移酶(GST)和谷胱甘肽还原酶(GSHR)外,谷胱甘肽过氧化物酶(GSHPx)、还原型谷胱甘肽(GSH)、硒水平均高于转化株(BHK-21/PyY);培养基中加入维生素E,非转化株比转化株摄入更多的维生素E;而转化株的内源性丙二醛(MDA)的产生多于非转化株。在铁催化的过氧化条件下,除硒、GST和GSHR外,二株细胞内上述抗氧化物指标都显著下降,MDA产生显著增加。除GSHPx外,非转化株的这种上升和下降的变化幅度均大于转化株。提示:自由基代谢水平在正常及恶性细胞之间,至少在上述二株细胞之间有所不同;正常细胞对过氧化的敏感性高于恶性细胞。

The Present

为了了解烧伤延迟复苏后肠粘膜氧自由基损伤情况及其对肠源性细菌、内毒素移位的影响,将66只悉生大鼠分为以下四组:(1)对照组(n=6)。(2)立即复苏组(n=24),40%烫伤后立即按Parkland公式复苏。(3)延迟复苏组(n=24),伤后6小时开始复苏。(4)药物治疗组(n=12),大鼠延迟复苏加上维生素C、E联合治疗。在伤后8、24、48和72小时活杀动物(各时间点6只)进行下列指标检测:回肠粘膜超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSHPx)及丙二醛(MDA)含量,回肠粘膜病理形态学观察、二胺氧化酶(DAO)活性,血和肠系膜淋巴结、肝、脾、肾、肺细菌培养,血浆内毒素水平。结果显示,伤后SOD、GSHPx含量下降,MDA升高,同时肠粘膜病理改变加重、DAO活性下降,血和脏器细菌移位率、血浆内毒素水平增高。这些改变在延迟组更明显,使用维生素C、E治疗后减轻。表明,烧伤延迟复苏加重肠粘膜氧自由基的损伤,促进肠道细菌和内毒素移位。

 
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