METHODS: Eighty newborns with apnea combined with hypoxic ischemic encephalopathy receiving treatment in Department of Pediatrics in Lianjiang People's Hospital were selected from January 2002 to March 2004 and divided randomly into 2 groups: routine drug group and high pressure oxygen treatment group with 40 cases in each group.
Methods: The study was conducted on 283 preterm infants chosen from the cases in Neonatology department of our hospital between January 2003 and December 2004. Logistic regression analysis was adopted to analyze 12 factors including sex, delivery way, birth-weight、 gestation, asphyxia、 multiple births, inner-uterus apnea, pregnancy-induced hypertension, placenta previa, oxygen therapy et al and these factors were chosen from mother's factors, fetal factors, delivery factors and therapy factors.
Cerebral blood flow of 10 asphyxiated term newborns was continuously measured during the first 7 days of life and compared with that of 10 normal term infants by CDI.
It is concluded that low CBF plays a key role in brain damage of post-asphyxiated newborns and RI may be an important parameter in the evaluation prognosis.
Urinary ET levels were measured by radioimmunoassay (RIA) in 17 healthy newborns and 20 asphyxiated neonates on days 1,3,7 after birth.
Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns
To evaluate the changes of 3', 5'-cyclic adenosine monophosphate (cAMP), thromboxane A2(TXA2) and prostacyclin (PGI2) in cerebrospinal fluid (CSF) in the asphyxiated newborn and explore their roles in hypoxic-ischamic brain damage (HIBD).
The sleep quality influenced the restoration of hemodynamics more than that of the cardiac rhythm, mainly when obstructive sleep apnea syndrome was present.
In apnea testing, however, both the duration of testing and the required baseline of paCO2 are under dispute.
It is still being discussed if patients with apnea-associated bradyarrhythmias require the implantation of a permanent pacemaker.
In patients with sleep-related breathing disorders (SRBD), it is assumed that apnea-associated changes of hemodynamics, blood gases, and rheology lead to a higher frequency of myocardial infarction during sleep.
Introduction Obstructive sleep apnea syndrome (OSAS) is frequently associated with cardiovascular disease.