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p蛋白     
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  p 53 protein
     Alterations of the p14~(ARF) Gene in Non-Small Cell Lung Cancer and the Correlation of Its Expression with p16~(INK4a), p53 Protein
     非小细胞肺癌中p14~(ARF)基因的异常及其与p16~(INK4a)、p53蛋白表达相关性的研究
短句来源
     HLA-A2 Subtype Distribution among Beijing Chinese and Its Effect on CTL Response in Vitro to P53 Protein Based Synthetic Peptide Vaccine
     北京人群中HLA-A2亚型的分布及A2亚型对基于P53蛋白的合成肽疫苗体外诱导CTL反应的影响
短句来源
     High Expression of p53 Protein in Human Dendritic Cells as Cancer Vaccine
     高表达p53蛋白的树突状细胞肿瘤疫苗
短句来源
     OVEREXPRESSION OF p53 PROTEIN IN HUMAN NASOPHARYNGEAL CARCINOMA AND HEAD-NECK TUMORS
     p53蛋白在鼻咽癌组织中的过量表达
短句来源
     Overexpression of P53Protein in Human Cervical Carcinoma
     P53蛋白在子宫颈癌中的高表达
短句来源
更多       
  p 53
     Alterations of the p14~(ARF) Gene in Non-Small Cell Lung Cancer and the Correlation of Its Expression with p16~(INK4a), p53 Protein
     非小细胞肺癌中p14~(ARF)基因的异常及其与p16~(INK4a)、p53蛋白表达相关性的研究
短句来源
     HLA-A2 Subtype Distribution among Beijing Chinese and Its Effect on CTL Response in Vitro to P53 Protein Based Synthetic Peptide Vaccine
     北京人群中HLA-A2亚型的分布及A2亚型对基于P53蛋白的合成肽疫苗体外诱导CTL反应的影响
短句来源
     The Protein Overexpression of the Tumor Suppressor Gene p53 and Prognosis in Lung Cancer Patients Surgically Treated
     抑癌基因p53蛋白表达与肺癌预后的关系
短句来源
     High Expression of p53 Protein in Human Dendritic Cells as Cancer Vaccine
     高表达p53蛋白的树突状细胞肿瘤疫苗
短句来源
     Expression of p53 in Colorectai Carcinomas
     p53蛋白在大肠癌组织中的表达
短句来源
更多       
  p 53 proteins
     (2)The positive-expression rate of p53 proteins in group T3+T4 was 92.5%(37/40),in group T1+T2 was 76.6%(49/64). The difference was statistically significant(X~2=4.37,P=0.037).
     T3+T4组 p53蛋白的阳性表达率92.5%(37/40),T1+T2组 p53蛋白阳性表达率为76.6%(49/64),2组之间差异有统计学意义(X~2=4.37,P=0.037)。
短句来源
     Methods:Immunohistochemical method was employed to detect the expressions of p 33(ING1b) and p 53 proteins and HPV_(16/18) infection in 80 cases of cervical cancer to analyze their relationship.
     方法:应用免疫组织化学SP方法检测了80例宫颈癌组织中P 33ING1b和P 53蛋白的表达,分析HPV16/18型在宫颈癌中的感染率与P 33ING1b及P 53的关系。
短句来源
     Rate of positive cells of p53 proteins of RPMI 1640 control group were(41±13)% and that of SLFKP(160 and 320 μg/ml,48 h) group were(15±5)% and(13±6)%.
     对照组SGC-7901细胞的p53蛋白阳性标记率为(41±13)%,双苓扶正抗癌制剂(160和320μg/ml)2个给药组其p53蛋白阳性标记率分别为(15±5)%、(13±6)%。
短句来源
     The expression of MUC5AC,bc1-2 and P53 proteins in human colorectal adenomas and its significance
     大肠腺瘤MUC5AC、bc1-2和P53蛋白的表达及其意义
短句来源
     However, the expression of P21 WAF1 protein was correlated with clinical stages(P<0.05), but Cyclin D1 and P53 proteins were not(P>0.05).
     P21WAF1蛋白表达与卵巢癌的临床分期相关(P<0.05),CyclinD1、P53蛋白表达与卵巢癌的临床分期无关(P>0.05)。
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  protein p 53
     Study for the Expression and Relationship of P14~(ARF) Protein, P27~(kip1) Protein, p53 Protein and P14~(ARF) Gene Alteration in Human Glioma
     P14~(ARF)、P27~(kip1)及p53蛋白表达和P14~(ARF)基因改变与脑胶质瘤发生发展的相关性研究
短句来源
     The Expression and Clinical Significance of Bcl-2 Protein, P53 Protein and P170 Protein in Acute Leukemia
     急性白血病bcl-2蛋白、p53蛋白、p170蛋白的表达水平及临床意义
短句来源
     Results: The positive rates of Bcl 2 protein, P53 protein, ER, and PR in breast carcinoma tissues were 65.2%, 47.5%,75.4%, and 69.6% respectively.
     结果 :Bcl 2蛋白 ,P53蛋白 ,ER ,PR在乳癌组织中表达的阳性率分别为 65 .2 % ,47.5 % ,75 .4 % ,69.6 % ;
短句来源
     Expressions of P16 protein,P53 protein ,E-cadherin in the tissues of primary hepatocellular carcinoma
     P16蛋白、P53蛋白、上皮钙粘蛋白(E-cadherin)在原发性肝细胞癌中的表达
短句来源
     Role of cyclin D1 protein, p53 protein and DNA ploidy in judging malignancy and prognosis of lung cancer
     cyclin D1、p53蛋白及DNA倍体在评价肺癌预后中的作用
短句来源
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  p 53 protein
Versatile functions of p53 protein in multicellular organisms
      
Specific Features of p53 Protein Induction after Ionizing Radiation in Cells of Patients with Nijmegen Breakage Syndrome
      
In the NBS cells, the p53 protein was progressively accumulated with increasing radiation dose and reached the maximum 2 h after exposure to radiation at a dose of 5 Gy.
      
The amount of p53 protein was consistently lower than that in normal cells, which was correlated with low content of the WAF1, the protein regulated by p53 at the level of transcription.
      
In response to irradiation, the amount of p53 protein synthesized in patients with AT and NBS was significantly lower than that in normal cells.
      
更多          
  p 53
Further, manzamine A (50 μM) substantially down regulated the expression of p53 while sarcophine (50 μM) slightly induced the level of p21.
      
The aim of this study was to investigate the role of pirh2 (p53-induced RING-H2) protein in the proliferation, apoptosis and cell cycle control of the lung cancer cell line A549.
      
However pathway involved in such signaling at least partially is independent of p53 function.
      
Such are the suggested effects on telomerase of Myc, p53, Waf1, protein kinases B and C, Wnt5A, TGFβ, WT1, and estrogens.
      
However, Myc, p53, WT1, estrogens, protein kinases B and C, and TGFβ can also directly influence telomerase independently of the G1-S checkpoint mechanism.
      
更多          
  p 53 proteins
Objective: This study was designed to detect the expression of bcl-2 and p53 proteins in colorectal carcinomas and to determine their association with the patient survival and stage of the diseases.
      
Methods: Immunohistochemistry method was used to detect the expression of bcl-2 and p53 proteins in 93 cases of colorectal carcinoma.
      
The effect ofHelicobacter pylori infection on hMSH2 and P53 proteins in gastric carcinogenesis
      
By using immunohistochemistry, the expression levels of mitogen activated protein kinase (MAPK), Ras and P53 proteins, and byin situ hybridization, MAPK and ras mRNA expression levels were detected.
      
The present paper investigated the immunohistochemical overexpression of the mdm-2 and p53 proteins in 25 biopsy specimens of transitional cell bladder carcinomas (10 pT1 and 15 pT2 or higher stages).
      
更多          
  protein p 53
Expression ofmyc broke the regulation of the cell cycle, in particular, canceled the G1 phase arrest for cells with damaged DNA, despite the normal function of protein p53 and induction of the p53-responsive genep21Waf1 in these cells.
      
We studied the relation between genetic anomalies in thep73 gene encoding a product structurally and functionally similar to the protein p53 and the pathogenesis of non-small-cell lung carcinoma (NSCLC; 83 patients).
      
An immunohistochemical analysis revealed a reciprocal correlation between the expression of the proapoptotic protein p53 and the cell proliferation upon the action of lysine, asparagine, and glutamic acid.
      
The tumor suppressor protein p53 which can mediate an ionizing radiation-induced G1 arrest in mammalian cells, forms complexes with SV40 large T antigen (l-T-Ag).
      
Zinc inhibits the nuclear translocation of the tumor suppressor protein p53 and protects cultured human neurons from copper-indu
      
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