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Objective:To observe the influence of Zhechong on blood rheology and red cell immune function in chronic blood stasis rats model.Method:This model was made by imitating Yinxu Huowang.Whole blood viscosity and plasmatic viscosity were measured in capillary.Packed cell volume was measured in a routine test.Red cell immune function indexes were measured by Guo's methods,and there was a correlativity relating to blood viscosity.Result:It was showed that Zhechong not only lowered markedly whole blood viscosity,plasmatic... Objective:To observe the influence of Zhechong on blood rheology and red cell immune function in chronic blood stasis rats model.Method:This model was made by imitating Yinxu Huowang.Whole blood viscosity and plasmatic viscosity were measured in capillary.Packed cell volume was measured in a routine test.Red cell immune function indexes were measured by Guo's methods,and there was a correlativity relating to blood viscosity.Result:It was showed that Zhechong not only lowered markedly whole blood viscosity,plasmatic viscosity and packed cell volume but also promoted red cell immune function,which may be:①RBC C 3b receptor rosette rate(RCR 1R) could be enhanced,②RBC immune complexes rosette rate(RICR) could be reduced,③the serum rosette forming enhancing rate of RBC C 3b receptor(RFER) could be increased,④the serum rosette forming inhibitory rate of RBC C 3b receptor (RFIR) could be decreased.Moreover,there were the inverse correlation between blood viscositv and RCR 1R.Conclusion:Zhechong not only activate blood circulation against stasis but also promote red cell immune function. 摘要:目的:观察虫对慢性血瘀型大鼠血液流变性和红细胞免疫功能的影响。方法:模拟阴虚火旺复制慢性血瘀大鼠模型,用毛细血管法测定不同切速下的全血比粘度、血浆比粘度,常规法测定红细胞压积。参照郭氏法测定红细胞免疫粘附功能指标,并将其与血液流变性有关指标作一相关分析。结果:虫能明显降低瘀血大鼠的全血比粘度、血浆比粘度和红细胞压积;提高瘀血大鼠红细胞C3b受体花环率,使红细胞免疫复合物花环率下降,血清红细胞免疫粘附促进因子活性增强,而抑制因子减弱;血液粘度与红细胞C3b受体花环率的相关分析呈显著负相关。结论:虫不仅有活血化瘀作用,还具有促进红细胞免疫功能的功效。
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