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胰腺癌痛的
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  pancreatic cancer pain
     CT-guided neurolytic celiac plexus block for the treatment of intractable pancreatic cancer pain
     CT引导下腹腔神经丛毁损性阻滞治疗顽固性胰腺癌痛的临床观察
短句来源
     Objective:The effects and the complications of percutaneous puncture and neurolytic celiac plexus block guided by CT were studied for treating pancreatic cancer pain.
     目的:观察CT引导下腹腔神经丛毁损性阻滞对顽固性胰腺癌痛的镇痛效果、并发症及对患者生活质量的影响。
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  “胰腺癌痛的”译为未确定词的双语例句
     Objective To evaluate safety and effectiveness of endoscopic ultrasound guided celiac plex us neurolysis (EUS-CPN) for analgesia of pancreatic carcinoma pain.
     目的探讨内镜超声(EUS)引导下腹腔神经丛注射无水酒精对胰腺癌痛的治疗作用。
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  相似匹配句对
     Carcinoma of the Pancreas
     (腺癌)(Ⅰ)
短句来源
     Quantitative analysis of AgNORs in pancreatic adenocarcinoma
     腺癌AgNORs的定量分析
短句来源
     CT-guided neurolytic celiac plexus block for the treatment of intractable pancreatic cancer pain
     CT引导下腹腔神经丛毁损性阻滞治疗顽固性腺癌痛的临床观察
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  pancreatic cancer pain
Techniques and results of neurolysis for chronic pancreatitis and pancreatic cancer pain
      
This review highlights the techniques of celiac plexus neurolysis and celiac block and their status in the treatment of chronic pancreatitis and pancreatic cancer pain.
      
Neurolytic celiac plexus block (NCPB) is commonly performed to relieve pancreatic cancer pain.
      
In particular, neurolytic celiac plexus block has been advocated for pancreatic cancer pain.
      
The technique for percutaneous and open neurolytic celiac plexus injection, using ethanol or phenol, for relief of intractable pancreatic cancer pain has been well described.
      
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Purpose:To study the effects on T lymphocyte subtypes with chemical splanchic denervation for patients with pancreatic carcinoma and intractable pain.Methods:32 cases with advanced pancreatic carcinoma accepted chemical splanchic denervation-pure alcohol injection around celiac ganglion guided by B US to relieve the severe pain. The fasting peripheral blood concentration of CD + 3 ,CD + 4 ,CD + 8 and β endorphin were determined before treatment ,3rd,7th,15th and 30th day after therapy. 38...

Purpose:To study the effects on T lymphocyte subtypes with chemical splanchic denervation for patients with pancreatic carcinoma and intractable pain.Methods:32 cases with advanced pancreatic carcinoma accepted chemical splanchic denervation-pure alcohol injection around celiac ganglion guided by B US to relieve the severe pain. The fasting peripheral blood concentration of CD + 3 ,CD + 4 ,CD + 8 and β endorphin were determined before treatment ,3rd,7th,15th and 30th day after therapy. 38 healthy persons were taken as control group.Results:The percentage of CD + 3 ,CD + 4 ,CD 8+ cell were apparently decreased in patients with pancreatic carcinoma comparing with control group( P <0.01), and the level of CD + 3 ,CD + 4 ,CD 8+ cell and β EP obviously increased after chemical splanchic denervation with significant difference(7 th day , P <0.05; P <0.01). Moreover, the change of β EP (3rd day , P <0.01) was found earlier than T lymphocyte subtypes (7th day , P <0.05). Conclusions:Our results suggest that chemical splanchic denervation could markely improve the inhibition of T lymphocyte subtypes on patients suffering intractable pain with pancreatic carcinoma, and β EP might participate in the immune regulative course.

目的 :探讨化学性内脏神经去除对胰腺癌痛患者淋巴细胞T亚群水平的影响。方法 :采用B超介导腹腔神经节无水乙醇注射对 32例胰腺癌患者实施化学性内脏神经去除治疗 ,以缓解剧烈癌性疼痛。分别在治疗前、治疗后 3、7、1 5、30天检测外周血CD+ 3 、CD+ 4 、CD+ 8和 β 内啡呔 (β EP)水平 ,38例健康体检者作为正常对照。 结果 :32例胰腺癌痛患者镇痛治疗前CD+3 、CD+4 、CD+8水平明显低于对照组 (P <0 .0 1 ) ;化学性内脏神经去除术治疗后 ,癌痛组患者CD+3 、CD+4 、CD+8水平和血浆 β EP含量明显上升 ,较治疗前有显著性差异 (第 7天 ,P <0 .0 5 ;P <0 0 1 ) ;血浆 β EP变化 (第 3天 ,P <0 .0 1 )早于T亚群 (第 7天 ,P <0 .0 5)。结论 :化学性内脏神经去除术能明显改善胰腺癌痛患者T亚群抑制状态 ,β EP可能参与这一免疫调节

Objective: To explore the regulative effects on T lymphocyte subtypes with chemical impairment of celiac ganglion in patients with pancreatic carcinoma and intractable pain. Methods: 32 cases with advanced pancreatic carcinoma accepted chemical splanchic denervation pure alcohol injection around celiac ganglion guided by B us to relieve the severe pain.The fasting peripheral blood concentration of CD + 3 ,CD + 4 ,CD + 8 (Cluster of Differentiation, CD) and β endorphin(β...

Objective: To explore the regulative effects on T lymphocyte subtypes with chemical impairment of celiac ganglion in patients with pancreatic carcinoma and intractable pain. Methods: 32 cases with advanced pancreatic carcinoma accepted chemical splanchic denervation pure alcohol injection around celiac ganglion guided by B us to relieve the severe pain.The fasting peripheral blood concentration of CD + 3 ,CD + 4 ,CD + 8 (Cluster of Differentiation, CD) and β endorphin(β EP)were determined before treatment,3rd,7th,15th and 30th day after therapy. 38 healthy persons were taken as control group. Results: The percentages of CD + 3 ,CD + 4 ,CD + 8 cell were apparently decreased in patients with pancreatic carcinoma comparing with the control group( P< 0.01) before chemical impairment of celiac ganglion, and the level of CD + 3 ,CD + 4 ,CD + 8 cell and β EP obviously increased after the therapy with significant difference (7th day , P< 0.05 ; P< 0.01). Moreover, the change of β EP (3rd day, P< 0.01) was found earlier than T lymphocyte subtypes (7th day , P< 0.05). Conclusion: Chemical impairment of celiac ganglion could evidently improve the inhibition of T lymphocyte subtypes on patients suffering intractable pain with pancreatic carcinoma, andβ EP might participate in the immuno regulative course.

目的 :探讨化学性腹腔神经节毁损对胰腺癌痛患者T淋巴细胞亚群的调节作用。方法 :采用B超介导细针穿刺 ,对 32例胰腺癌患者腹腔神经节注射无水乙醇实施化学性毁损治疗 ,以缓解剧烈癌性疼痛。分别在治疗前及治疗后 3,7,15 ,30d检测外周血CD+3 ,CD+4 ,CD+8和β EP水平 ;38例健康体检者作为对照。结果 :治疗前 ,32例胰腺癌痛患者CD+3 ,CD+4 ,CD+8水平明显低于对照组 (P <0 .0 1) ;化学性神经毁损后 ,癌痛组患者CD+3 ,CD+4 ,CD+8水平和血浆β EP含量明显上升 ,较治疗前有显著性差异 (7thday ,P <0 .0 5 ;P <0 .0 1) ;β EP变化 (3rdday ,P <0 .0 1)早于T亚群 (7thday ,P <0 .0 5 )。 结论 :化学性腹腔神经节毁损能明显改善胰腺癌痛患者T亚群抑制状态 ,β EP可能参与这一免疫调节。

Objective:The effects and the complications of percutaneous puncture and neurolytic celiac plexus block guided by CT were studied for treating pancreatic cancer pain.Method:46 patients with severe pancreatic cancer pain were treated by CT-guided percutaneous puncture from back approach and neurolytic celiac plexus block with alcohol.Result:The cancer pain in all patients was controlled in one week after the block. By the results of following up at 7th,14th,30th,60th,and 90th day after the treatment the pain...

Objective:The effects and the complications of percutaneous puncture and neurolytic celiac plexus block guided by CT were studied for treating pancreatic cancer pain.Method:46 patients with severe pancreatic cancer pain were treated by CT-guided percutaneous puncture from back approach and neurolytic celiac plexus block with alcohol.Result:The cancer pain in all patients was controlled in one week after the block. By the results of following up at 7th,14th,30th,60th,and 90th day after the treatment the pain VAS,pain relief rate,life quality were all improved significantly with no severe complications. Most patients died of cancer with no pain or with only light pain.Conclusion:Percutaneous puncture and neurolytic celiac plexus block by the guide of CT is a method with good analgisic effect and less complications for the treatment of pancreatic cancer pain.Author′s address Pain Medical Center,Xuanwu Hospital,Beijing,100053

目的:观察CT引导下腹腔神经丛毁损性阻滞对顽固性胰腺癌痛的镇痛效果、并发症及对患者生活质量的影响。方法:46例顽固性胰腺癌症疼痛患者,在CT引导监视下经背侧入路经皮穿刺,行腹腔神经丛无水酒精阻滞治疗。结果:治疗后1周内全部患者疼痛减轻或消失。在治疗后第7、14、30、60、90天,患者的疼痛评分、疼痛缓解率、生活质量均明显改善,大多数患者临终前无痛或仅轻度疼痛。治疗过程中和治疗后未发生严重并发症。结论:CT引导下腹腔神经丛阻滞治疗顽固性胰腺癌痛的疗效确切,安全性高。

 
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