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   卵巢病理学 的翻译结果: 查询用时:0.22秒
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卵巢病理学
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  “卵巢病理学”译为未确定词的双语例句
     On week 16,the mice were killed and ovarian serial section was prepared for microscopy.
     第16周取双侧卵巢作石蜡连续切片,光镜观察卵巢病理学变化。
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     Pathology;
     病理学;
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     A Pathological Study on Mucinous Tumors of the Ovary
     卵巢粘液性肿瘤病理学观察
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     OVARIAN AUTOTRANSPOSITION
     卵巢自体移植
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     Premature Ovarian Failure
     卵巢早衰
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     Veterinary Pathology
     兽医病理学
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The effects of styrene on

应用放射免疫分析法(RIA)和电镜学,研究了苯乙烯对雌鼠的性激素、促性腺激素和动情周期的影响以及卵巢病理学改变,苯乙烯剂量分别为0.3g/kg,0.5g/kg和1.0g/kg。实验结果指出,雌鼠血清雌二醇(E2)、促卵泡生成素(FSH)和促黄体生成素(LH)含量与染毒前比较明显降低(P<0.05)。雌鼠卵巢重量明显减轻,非动情期和动情周期显著延长,与对照组比较差异非常显著(P<0.01).提示,苯乙烯对雌鼠性腺功能有影响。

Objective To explore the pathological changes of the contralateral ovary in patients with stage Ⅰa ovarian cancer. Method The ovarian tissues taken from 42 control patients who had ovaries resections due to benign diseases were compared with the ovarian tissue which obtained from the contralateral ovary of 42 ovarian cancer cases. Pathological indexes including inclusion cysts were studied. Results In both study group and control group, the mean numbers of inclusion cysts were 3(0-40) vs 1(0-12),the frenquency...

Objective To explore the pathological changes of the contralateral ovary in patients with stage Ⅰa ovarian cancer. Method The ovarian tissues taken from 42 control patients who had ovaries resections due to benign diseases were compared with the ovarian tissue which obtained from the contralateral ovary of 42 ovarian cancer cases. Pathological indexes including inclusion cysts were studied. Results In both study group and control group, the mean numbers of inclusion cysts were 3(0-40) vs 1(0-12),the frenquency of serous metaplasia was 66.7% vs 34.6%. The difference was significant. An age related increase in the number of inclusion cysts was noted in the cancer patients but not in the control group. Conclusions Ovarian inclusion cysts could play an important role in the genesis of ovarian cancer.

目的 研究Ⅰa期卵巢癌对侧卵巢的病理学变化。 方法 选择Ⅰa期卵巢癌对侧卵巢 4 2例 (研究组 ) ,观察卵巢内包涵囊肿ICs等病理学指标 ,并与非肿瘤性卵巢组织 4 2例 (对照组 )进行比较。 结果 研究组ICs数平均 3( 0~ 4 0 )个 ,且随年龄的增加而增多 ,对照组为 1( 0~ 12 )个 ;研究组ICs上皮浆液性化生占 6 6 .7% ,对照组为 34.6 %。均有显著性差异 (P <0 .0 1)。 结论 ICs可能在卵巢癌的发生中发挥重要作用

Aim: To evaluate the mucosal immune response, anti-fertility, change of ovarian histology induced by oral immunization with DNA contraceptive vaccine Chitosan/pVAX1-pZP3α nanoparticles and explore the feasibility of taking advantage of mucosal immunity to overcome ovary dysfunction which was often caused by immunization of zona pellucida antigen. Methods: Female mice were divided into two different groups of ten. 0.5 mL Chitosan/pVAX1-pZP3α nanoparticles containing 50 μg DNA was prepared and orally administered...

Aim: To evaluate the mucosal immune response, anti-fertility, change of ovarian histology induced by oral immunization with DNA contraceptive vaccine Chitosan/pVAX1-pZP3α nanoparticles and explore the feasibility of taking advantage of mucosal immunity to overcome ovary dysfunction which was often caused by immunization of zona pellucida antigen. Methods: Female mice were divided into two different groups of ten. 0.5 mL Chitosan/pVAX1-pZP3α nanoparticles containing 50 μg DNA was prepared and orally administered into each experimental mouse on weeks 0,3 and 6 whereas the same dose of chitosan without DNA for the control. Serum and vaginal wash samples collected every two weeks were used to determine anti-pZP3 IgA and IgG response by ELISA. On week 12, these female mice were mated with male mice and were checked for pregnant. On week 16, the mice were killed and ovarian serial section was prepared for microscopy. Results: Anti-pZP3 IgA antibody response could be detected in serum from eight experimental mice and vaginal washes from five, intensity and lasting time varying over a wide range among different mouse. Five experimental mice didn't fall pregnant while the control did and anti-fertility was relative to Anti-pZP3 IgA antibody level in mating mice. There was no difference about ovarian histology among unpregnant, pregnant experimental mice and control mice. Conclusion:Oral immunization with chitosan/pVAX1-pZP3α nanoparticles could induce mucosal immune response in genital tract and inhibit fertility without any effect on ovarian structure in mice. Inducing mucosal immunity would be a promising regimen for study of developing a safe zona pellucida contraceptive vaccine.

 目的:评价口服卵透明带DNA避孕疫苗pVAX1-pZP3α壳聚糖纳米微粒诱发的黏膜免疫反应、抗生育作用和对卵巢结构的影响,探讨用黏膜免疫避免卵透明带抗原免疫引起卵巢功能紊乱的可行性。方法:制备pVAX1-pZP3α壳聚糖纳米微粒,10只昆明系小鼠口服免疫,第3周和第6周分别加强免疫一次,剂量为0 5mL/只,含pVAX1-pZP3αDNA50μg;对照组10只雌小鼠口服相同剂量不含pVAX1-pZP3α的壳聚糖。免疫前和免疫后隔周取小鼠血清、阴道冲洗液,用ELISA法检测抗pZP3IgA和IgG。首次免疫后第12周雌雄合笼交配,统计雌鼠怀孕情况;解剖取出双侧卵巢,制作石蜡切片,光镜观察卵巢病理学变化。结果:免疫组80%小鼠的血清和50%小鼠的阴道冲洗液可检测到抗pZP3IgA,反应强度与持续时间有明显的个体差异;免疫组5只小鼠未怀孕,对照组全部怀孕,抗生育效果与合笼时抗pZP3IgA反应有关;免疫组未怀孕小鼠卵巢组织结构与免疫组怀孕小鼠及对照组小鼠无差别。结论:口服pVAX1-pZP3α壳聚糖纳米微粒免疫小鼠能诱发生殖道黏膜免疫反应,发挥抗生育作用,对卵巢组织结构没有影响。黏膜免疫是克服卵透明带...

 目的:评价口服卵透明带DNA避孕疫苗pVAX1-pZP3α壳聚糖纳米微粒诱发的黏膜免疫反应、抗生育作用和对卵巢结构的影响,探讨用黏膜免疫避免卵透明带抗原免疫引起卵巢功能紊乱的可行性。方法:制备pVAX1-pZP3α壳聚糖纳米微粒,10只昆明系小鼠口服免疫,第3周和第6周分别加强免疫一次,剂量为0 5mL/只,含pVAX1-pZP3αDNA50μg;对照组10只雌小鼠口服相同剂量不含pVAX1-pZP3α的壳聚糖。免疫前和免疫后隔周取小鼠血清、阴道冲洗液,用ELISA法检测抗pZP3IgA和IgG。首次免疫后第12周雌雄合笼交配,统计雌鼠怀孕情况;解剖取出双侧卵巢,制作石蜡切片,光镜观察卵巢病理学变化。结果:免疫组80%小鼠的血清和50%小鼠的阴道冲洗液可检测到抗pZP3IgA,反应强度与持续时间有明显的个体差异;免疫组5只小鼠未怀孕,对照组全部怀孕,抗生育效果与合笼时抗pZP3IgA反应有关;免疫组未怀孕小鼠卵巢组织结构与免疫组怀孕小鼠及对照组小鼠无差别。结论:口服pVAX1-pZP3α壳聚糖纳米微粒免疫小鼠能诱发生殖道黏膜免疫反应,发挥抗生育作用,对卵巢组织结构没有影响。黏膜免疫是克服卵透明带抗原免疫引起卵巢功能紊乱的一种值得深入研究的方法。

 
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