助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   慢性丙型肝炎病毒感染 的翻译结果: 查询用时:0.02秒
图标索引 在分类学科中查询
所有学科
感染性疾病及传染病
消化系统疾病
更多类别查询

图标索引 历史查询
 

慢性丙型肝炎病毒感染
相关语句
  chronic hepatitis c virus infection
     Effect of IL-12 on lymphoproliferative response in individuals with chronic hepatitis C virus infection
     IL-12对慢性丙型肝炎病毒感染者淋巴细胞增殖的影响
短句来源
     The extent of liver steatosis in chronic hepatitis C virus infection is mirrored by caspase activity in serum
     血清中半胱天冬氨酸蛋白酶活性可反映慢性丙型肝炎病毒感染肝脂肪化程度
短句来源
     Efficacy of interferon monotherapy in young adult patients with chronic hepatitis C virus infection
     单一干扰素治疗年轻慢性丙型肝炎病毒感染者的疗效
短句来源
     Enhanced ability of peripheral invariant natural killer T-cells to produce IL-13 in chronic hepatitis C virus infection
     慢性丙型肝炎病毒感染者外周血恒定型自然杀伤T细胞分泌IL-13的能力增强
短句来源
     Treatment of chronic hepatitis C virus infection via antioxidants: Results of a phase I clinical trial
     抗氧化剂治疗慢性丙型肝炎病毒感染:I期临床试验结果
短句来源
  “慢性丙型肝炎病毒感染”译为未确定词的双语例句
     Background/Aims: To investigate the relationship between T lymphocyte subsets, serum levels of IL-2, sIL-2R and HCV RNA proliferation state.
     目的:探讨慢性丙型肝炎病毒感染患者HCV RNA增殖状态与T细胞亚群功能及血浆中IL-2和SIL-2R活性的关系。
短句来源
     Objective To define the role of HCV-specific cytotoxic T lymphocytes (CTL) in chro-nic hepatitis C virus (HCV) infection.
     目的 阐明丙型肝炎病毒 (HCV)特异性细胞毒性T淋巴细胞 (CTL)在慢性丙型肝炎病毒感染中的作用。
短句来源
     Diagnosis and treatment of chronic hepatitis C infection
     慢性丙型肝炎病毒感染的诊断和治疗
短句来源
     Analyses of anti-HCV detected by ELISA and HCV RNA detected by RT-nPCR in chronic hepatitis C virus infectors
     ELISA联合RT-nPCR检测慢性丙型肝炎病毒感染者结果分析
短句来源
     Objective In order to provide the basis for the clinical test and the blood station screening the health donator, the results of anti-HCV tested by ELISA (enzyme-linked-immuno-absorbed assay ) and HCV RNA tested by RT-nPCR(reverse-transcript-nested-polymerase-chain-reaction) were compared in the chronic hepatitis C virus infectors.
     目的对比酶联免疫吸附试验(ELISA)和逆转录套式聚合酶链反应(RT-nPCR)检测慢性丙型肝炎病毒感染者血清抗-HCV和HCVRNA结果。
短句来源
更多       
  相似匹配句对
     Diagnosis and treatment of chronic hepatitis C infection
     慢性肝炎病毒感染的诊断和治疗
短句来源
     THE CORRELATIVE MECHANISM FOR THE CHRONICITY OF HCV INFECTION
     肝炎病毒感染慢性化的相关机制
短句来源
     An Epidemiological Study on the Rate of Becoming Chronic in HCV Infection
     肝炎病毒感染慢性转化率的流行病学研究
短句来源
     Hepatitis C virus(HCV)is an important cause of chronic liver disease.
     肝炎病毒感染是导致慢性肝病的重要原因。
短句来源
     HepatitisBandHepatitisCVirusinfection andchronicliverdisease
     乙肝炎病毒感染慢性肝病
短句来源
查询“慢性丙型肝炎病毒感染”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  chronic hepatitis c virus infection
Renal involvement in patients with chronic hepatitis C virus infection
      
There is an increasing recognition of the association between chronic hepatitis C virus infection and glomerular diseases.
      
New therapies for chronic hepatitis C virus infection
      
C-C chemokine receptor 2 and C-C chemokine receptor 5 genotypes in patients treated for chronic hepatitis C virus infection
      
Biclonal gammopathy and platelet antibodies in a patient with chronic hepatitis C virus infection and mixed cryoglobulinemia
      
更多          


Background/Aims: To investigate the relationship between T lymphocyte subsets, serum levels of IL-2, sIL-2R and HCV RNA proliferation state. Methods: Peripheral blood of 75 patients were determined for T lymphocyte subsets by indirect immnofluo rescence, levels of IL-2 and sIL-2R by indirect immunofluorescence and ELISA and HCV RNA by RT-PCR respectively. 47 cases were HCV RNA postive, 28 were negative. Results: CD3+, CD4+ T lymphocyte subsets levels, CD4+/CD8+ ratio and serum IL-2 levels were significantly...

Background/Aims: To investigate the relationship between T lymphocyte subsets, serum levels of IL-2, sIL-2R and HCV RNA proliferation state. Methods: Peripheral blood of 75 patients were determined for T lymphocyte subsets by indirect immnofluo rescence, levels of IL-2 and sIL-2R by indirect immunofluorescence and ELISA and HCV RNA by RT-PCR respectively. 47 cases were HCV RNA postive, 28 were negative. Results: CD3+, CD4+ T lymphocyte subsets levels, CD4+/CD8+ ratio and serum IL-2 levels were significantly lower in patients than in healthy controls (P<0.01), sIL-2R levels increased significantly (P<3.01). T lymphocyte subsets, CD4+/CD8+ ratio and IL-2 levels were significantly lower in HCV RNA positive patients than in HCV RNA negative patients (P<0.01). Conclusions: Patients with chronic HCV infection may have cellular immune dysfunction, HCV RNA positive patients were more obvious than HCV RNA negative. These results suggested that cellular immune suppression may play an important role in HCV RNA persistant proliferation.

目的:探讨慢性丙型肝炎病毒感染患者HCV RNA增殖状态与T细胞亚群功能及血浆中IL-2和SIL-2R活性的关系。方法:以间接免疫荧光法、ELISA法和RT-PCR分别检测75例慢性HCV感染患者(其中HCV RNA阳性47例,HCV RNA阴性28例)外周血T细胞亚群、IL-2、sIL-2R的水平和HCV RNA。结果:慢性HCV感染患者周围血CD_3~+、CD_4~+淋巴细胞亚群,CD_4~+/CD_3~+比值及IL-2水平均显著低于正常对照组(P<0.01),而sIL-2R明显升高(P<0.01);血清HCV RNA阳性患者T细胞亚群,CD_4~+/CD_3~+比值及IL-2水平显著低于HCV RNA阴性患者(P<0.01)。结论:慢性HCV感染患者存在机体细胞免疫功能低下,HCV RNA阳性患者较阴性患者更甚,提示细胞免疫功能受抑可能是HCV持续增殖的原因。

Objective To define the role of HCV-specific cytotoxic T lymphocytes (CTL) in chro-nic hepatitis C virus (HCV) infection. Methods HCV-specific CTL activity (HCV-CTL) was assessed in the liver and peripheral blood cells in 62 patients with chronic hepatitis C and 8 non-HCV-infection controls by using bulk-expanded liver/peripheral blood mononuclear lymphocytes (PBMC)-derived CD8+ cells as effector cells, EBV-transformed B cells as autologous target cells and recombinant vaccinia vectors expressing various regions...

Objective To define the role of HCV-specific cytotoxic T lymphocytes (CTL) in chro-nic hepatitis C virus (HCV) infection. Methods HCV-specific CTL activity (HCV-CTL) was assessed in the liver and peripheral blood cells in 62 patients with chronic hepatitis C and 8 non-HCV-infection controls by using bulk-expanded liver/peripheral blood mononuclear lymphocytes (PBMC)-derived CD8+ cells as effector cells, EBV-transformed B cells as autologous target cells and recombinant vaccinia vectors expressing various regions of the HCV genome as transduction vector, in a standard chromium release assay. Results HCV-CTL activity was detected from the liver in 28 of the 60 patients (46.7%), but not from PBMC. CTL activity could not be detected from the liver and PBMC in all non-HCV-infection controls. Five patients with non-type 1 HCV infection were found to have HCV-specific CTL activity against HCV type 1 epitope. Compared with the patients without detectable HCV-specific CTL activity based on our assay, those exhibiting CTL activity had higher serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, higher histologic activity indices and lower levels of HCV RNA (all P< 0.01). Conclusions 1) HCV-specific CTL is found mainly in the liver rather than in peripheral blood, suggesting a tissue-specific localization with HCV-specific CTL; 2) Cross-genotype CTL activity exists; 3) Patients with HCV-specific CTL activity in the liver have more active liver disease and lower levels of viremia; 4) Cellular immune response mediated by HCV-specific CTL plays an important role in the pathogenesis and control of hepatitis C virus infection.

目的 阐明丙型肝炎病毒 (HCV)特异性细胞毒性T淋巴细胞 (CTL)在慢性丙型肝炎病毒感染中的作用。方法 用标准铬释放法 (以从患者肝组织或外周血单个核细胞中经选择性克隆扩增后的CD8+细胞为效应细胞 ,经EB病毒转染的自身B淋巴母细胞为靶细胞 ,由能表达HCV1型核心区基因的重组痘苗病毒作为转导载体 )对 62例慢性丙型肝炎患者肝组织及外周血单个核细胞(PBMC)中的HCV特异性CTL活性 (HCV CTL)进行检测 ,8例非HCV感染的肝病患者作为对照。结果  62例慢性丙型肝炎患者中 ,共有 2 8例 ( 4 6.7%)肝组织中检测出HCV CTL活性 ,但HCV CTL在PBMC中未检出。对照组患者肝组织及PBMC中均未检出。 5例非HCV1感染的丙型肝炎患者检测出针对HCV1型表位的HCV CTL。HCV CTL阳性的丙型肝炎患者血清丙氨酸转氨酶 (ALT)、天门冬氨酸转氨酶 (AST)水平及肝组织活动指数均明显高于HCV CTL阴性的患者 ,而其血清HCVRNA水平则显著低于后者 (P <0 .0 1)。结论  1.HCV CTL主要存在于肝组织内 ;2 .存在型交叉性HCV CTL...

目的 阐明丙型肝炎病毒 (HCV)特异性细胞毒性T淋巴细胞 (CTL)在慢性丙型肝炎病毒感染中的作用。方法 用标准铬释放法 (以从患者肝组织或外周血单个核细胞中经选择性克隆扩增后的CD8+细胞为效应细胞 ,经EB病毒转染的自身B淋巴母细胞为靶细胞 ,由能表达HCV1型核心区基因的重组痘苗病毒作为转导载体 )对 62例慢性丙型肝炎患者肝组织及外周血单个核细胞(PBMC)中的HCV特异性CTL活性 (HCV CTL)进行检测 ,8例非HCV感染的肝病患者作为对照。结果  62例慢性丙型肝炎患者中 ,共有 2 8例 ( 4 6.7%)肝组织中检测出HCV CTL活性 ,但HCV CTL在PBMC中未检出。对照组患者肝组织及PBMC中均未检出。 5例非HCV1感染的丙型肝炎患者检测出针对HCV1型表位的HCV CTL。HCV CTL阳性的丙型肝炎患者血清丙氨酸转氨酶 (ALT)、天门冬氨酸转氨酶 (AST)水平及肝组织活动指数均明显高于HCV CTL阴性的患者 ,而其血清HCVRNA水平则显著低于后者 (P <0 .0 1)。结论  1.HCV CTL主要存在于肝组织内 ;2 .存在型交叉性HCV CTL ;3 .HCV CTL活性阳性的患者较HCV CTL活性阴性者具有较高的疾病活动度及较低的病毒血症水平 ;4 .HCV特异性CTL在丙型肝炎的发病机制及疾病控制中起重要作用。

Objective To study the relationship between HCV infection and the development of type Ⅱ diabetes mellitus. Methods 1.The case record files of 126 patients with chronic hepatitis C vs. 227 with chronic hepatitis B were reviewed and the laboratory and demographic data were extracted. 2. Anti HCV and HBsAg were determined for 160 type Ⅱ diabetes patients and 223 healthy adults by ELISA. Results 1. The occurrence of diabetes in patients with chronic hepatitis C was 19.05%, higher than 8.37% in patients with...

Objective To study the relationship between HCV infection and the development of type Ⅱ diabetes mellitus. Methods 1.The case record files of 126 patients with chronic hepatitis C vs. 227 with chronic hepatitis B were reviewed and the laboratory and demographic data were extracted. 2. Anti HCV and HBsAg were determined for 160 type Ⅱ diabetes patients and 223 healthy adults by ELISA. Results 1. The occurrence of diabetes in patients with chronic hepatitis C was 19.05%, higher than 8.37% in patients with chronic hepatitis B ( P <0.01). Age and HCV infection were independent risk factors for diabetes. 2. Five patients with type Ⅱ diabetes were anti HCV positive (3.12%) while none of the 223 healthy adults was anti HCV positive ( P <0.05). Seven patients with diabetes (4.37%) and 12 healthy adults (5.38%)were HBsAg positive ( P >0.05). Conclusions 1. The occurrence of diabetes was significantly higher in patients with HCV related liver disease than in patients with HBV related liver disease. 2. The occurrence of anti HCV was higher in diabetes patients than in healthy adults.HCV may play a role in the development of diabetes mellitus.

目的 探讨慢性丙型肝炎病毒 (HCV)感染与Ⅱ型糖尿病发病的关系。方法 ①对 2 2 7例慢性乙型肝炎 (乙型肝炎后肝硬化 86例 )与 12 6例慢性丙型肝炎患者 (丙型肝炎后肝硬化 3 0例 )进行病例分析研究 ,明确其是否合并糖尿病。②用ELISA方法对 160例Ⅱ型糖尿病患者及 2 2 3例体检人群进行抗HCV、HBsAg检测。结果 ① 12 6例慢性丙型肝炎患者合并Ⅱ型糖尿病 2 4例 (19.0 5 % ) ,2 2 7例慢性乙型肝炎患者合并Ⅱ型糖尿病 19例 (8.3 7% ) ,二者比较差异有显著性 (P <0 .0 1) ,年龄及丙型肝炎为发生糖尿病的独立危险因素。② 160例Ⅱ型糖尿病患者中抗HCV阳性 5例 (3 .12 % ) ,HBsAg阳性 7例 (4 3 7% ) ,2 2 3例体检人群抗HCV阳性 0例 ,与糖尿病人群差异有显著性 (P <0 .0 5 ) ,HBsAg阳性 12例 (5 .3 8% ) ,与糖尿病人群差异无显著性 (P >0 .0 5 )。结论 ①慢性丙型肝炎病毒感染易合并Ⅱ型糖尿病。②Ⅱ型糖尿病患者中丙型肝炎感染率高于普通人群 ,提示HCV感染与...

目的 探讨慢性丙型肝炎病毒 (HCV)感染与Ⅱ型糖尿病发病的关系。方法 ①对 2 2 7例慢性乙型肝炎 (乙型肝炎后肝硬化 86例 )与 12 6例慢性丙型肝炎患者 (丙型肝炎后肝硬化 3 0例 )进行病例分析研究 ,明确其是否合并糖尿病。②用ELISA方法对 160例Ⅱ型糖尿病患者及 2 2 3例体检人群进行抗HCV、HBsAg检测。结果 ① 12 6例慢性丙型肝炎患者合并Ⅱ型糖尿病 2 4例 (19.0 5 % ) ,2 2 7例慢性乙型肝炎患者合并Ⅱ型糖尿病 19例 (8.3 7% ) ,二者比较差异有显著性 (P <0 .0 1) ,年龄及丙型肝炎为发生糖尿病的独立危险因素。② 160例Ⅱ型糖尿病患者中抗HCV阳性 5例 (3 .12 % ) ,HBsAg阳性 7例 (4 3 7% ) ,2 2 3例体检人群抗HCV阳性 0例 ,与糖尿病人群差异有显著性 (P <0 .0 5 ) ,HBsAg阳性 12例 (5 .3 8% ) ,与糖尿病人群差异无显著性 (P >0 .0 5 )。结论 ①慢性丙型肝炎病毒感染易合并Ⅱ型糖尿病。②Ⅱ型糖尿病患者中丙型肝炎感染率高于普通人群 ,提示HCV感染与糖尿病的发生有一定关系 ,HCV感染可能为Ⅱ型糖尿病发病因素之一

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关慢性丙型肝炎病毒感染的内容
在知识搜索中查有关慢性丙型肝炎病毒感染的内容
在数字搜索中查有关慢性丙型肝炎病毒感染的内容
在概念知识元中查有关慢性丙型肝炎病毒感染的内容
在学术趋势中查有关慢性丙型肝炎病毒感染的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社