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淋巴细胞胞浆游离钙
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  lymphocytes ' cytoplasmic free calcium
     We studied the effects of oxymatine,an alkaloid from Sophra Flavesens Ait,on human andmouse's lymphocytes' cytoplasmic free calcium,calium uptaking,cAMP & cGMP level.
     本文研究了氧化苦参碱对淋巴细胞胞浆游离钙、钙摄取功能、cAMP 及cGMP 水平的影响。
短句来源
  lymphocyte cytosolic calcium
     Rat tail systolic press, lymphocyte cytosolic calcium ( i), ultrastructure of mesenteric artery ,plasma AngⅡwere measured before and after treatment.
     治疗前后检测鼠尾收缩压、淋巴细胞胞浆游离钙 [Ca2 + ]i、血浆AngⅡ和肠系膜动脉超微结构 .
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  “淋巴细胞胞浆游离钙”译为未确定词的双语例句
     Cytosolic calcium concentration and its relevance to respiratory burst in lymphocytes from asthmatic children
     哮喘患儿淋巴细胞胞浆游离钙离子浓度变化及其与呼吸爆发功能的关系
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     Objective To observe the effect in the process before and after treatment of Losartan in spontenously hypertensive rat (SHR) and controlled group(WKY) , and the changes of intralymphocytic calcium i,angiotensin Ⅱ(AngⅡ),and vascular wall ultrastructure.
     目的 观察氯沙坦 (Losartan)对自发性高血压大鼠 (SHR)及正常对照组 (WKY)的淋巴细胞胞浆游离钙[Ca2 + ]i、血管紧张素Ⅱ (AngⅡ )水平和血管壁超微结构的影响及其降压效应 .
短句来源
     Methods:The cytosolic calcium concentration 〔Ca2+〕i and superoxide generation in the peripheral lymphocytes were determined using Quin 2 as fluorescent indicator and the measurement of superoxide dismutaseinhibitable reduction of ferricytochrome C,respectively.
     方法:采用Quin2荧光技术直接测定淋巴细胞胞浆游离钙离子〔Ca2+〕i和细胞色素C还原法测定淋巴细胞呼吸爆发O÷2释放量。
短句来源
     Methods Blood pressure and Intralymphocytic free calcium concentrations were measured in 28 patients with essential hypertension and 21 healthy subjects controls, the changes of blood pressure, intralymphocytic free calcium concentrations and 24-hours ambulatory blood pressure monitoring (ABPM) in patients were observed before and after Felodipine extended release (Felodipine-ER) therapy for 4 weeks.
     方法 检测28例原发性高血压患者及相应对照组之血压及淋巴细胞胞浆游离钙浓度及非洛地平缓释片治疗四周后血压及淋巴细胞胞浆游离钙浓度的变化,并观察其治疗前后24h动态血压的变化。
短句来源
     Mean BP, lymphocytic intracellular free Ca2+,plasma Angiotensin Ⅱ. and left ventricular diastolic functionwere determined in patients with essential hypertension(stages Ⅰ, Ⅱ) before and after 4 weeks amlodipine treatment.
     测定Ⅰ、Ⅱ期高血压病患者给予氨氯地平治疗四周前后平均动脉压(MAP)、淋巴细胞胞浆游离钙[Ca2+]i、血管紧张素Ⅱ(AugⅡ)及左室舒张功能指标(E,A,E/A)。
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     These results suggested that, intralymphocytic free calcium concentration was increased in essential hypertensive patients.
     提示原发性高血压患者淋巴细胞胞浆游离浓度增高。
短句来源
     Effect of Nitrendipine on Intralymphocytic Free Calcium Concentration in Essential Hypertension
     原发性高血压患者淋巴细胞胞浆游离浓度及尼群地平治疗后的变化
短句来源
     After nitrendipine therapy,intralymphocytic free calcium concentration and blood pressure were markedly decreased.
     尼群地平治疗后淋巴细胞胞浆游离浓度和血压均显著下降。
短句来源
     We studied the effects of oxymatine,an alkaloid from Sophra Flavesens Ait,on human andmouse's lymphocytes' cytoplasmic free calcium,calium uptaking,cAMP & cGMP level.
     本文研究了氧化苦参碱对淋巴细胞胞浆游离摄取功能、cAMP 及cGMP 水平的影响。
短句来源
     Effects of cilazapril on the relationship between the concentrations of intralymphocytic free calcium and angiotensin in hypertensive patients
     抑平舒对高血压病患者的血压、淋巴细胞胞浆游离浓度、血管紧张素Ⅱ关系的影响
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  lymphocyte cytosolic calcium
Elevated lymphocyte cytosolic calcium in a subgroup of essential hypertensive subjects.
      


Intralymphocytic free calium concentrations were measured in 22 patients with essential hypertension and matched normotensive controls, the changes of intralymphocytic free calcium concentrations in patients were observed before and after nitrandipine therapy for 2 weeks. The results showed that: intralymphocytic free calcium concentrations were much higher in hypertensive patients than in normotensive controls. After nitrendipine therapy,intralymphocytic free calcium concentration and blood pressure were markedly...

Intralymphocytic free calium concentrations were measured in 22 patients with essential hypertension and matched normotensive controls, the changes of intralymphocytic free calcium concentrations in patients were observed before and after nitrandipine therapy for 2 weeks. The results showed that: intralymphocytic free calcium concentrations were much higher in hypertensive patients than in normotensive controls. After nitrendipine therapy,intralymphocytic free calcium concentration and blood pressure were markedly decreased. There was a positive correlation between the decreasing gradients of intralymphocytic free calcium concentration and diastolic blood pressure, and also mean blood pressure, but no significance correlation between the decreasing gradient of the calcium concentration and systolic blood pressure. These results suggested that, intralymphocytic free calcium concentration was increased in essential hypertensive patients. Calcium antagonist nitrendipine probably reduced the vascular smooth muscle tone by means of the decreasing of intracellular free calcium concentration and then lowered the blood pressure.

本文检测了22例原发性高血压患者及相应的正常对照之淋巴细胞胞浆游离钙浓度,并观察尼群地平治疗两周后患者淋巴细胞胞浆游离钙浓度的变化。结果表明:原发性高血压患者治疗前淋巴细胞胞浆游离钙浓度显著高于正常对照组。尼群地平治疗后淋巴细胞胞浆游离钙浓度和血压均显著下降。淋巴细胞胞浆游离钙浓度的下降幅度与舒张压及平均动脉压的下降幅度均呈正相关,与收缩压的下降幅度无显著相关。提示原发性高血压患者淋巴细胞胞浆游离钙浓度增高。钙离子拮抗剂尼群地平可能通过降低细胞胞浆游离钙的浓度而降低血管平滑肌张力,发挥其降压作用。

We studied the effects of oxymatine,an alkaloid from Sophra Flavesens Ait,on human andmouse's lymphocytes' cytoplasmic free calcium,calium uptaking,cAMP & cGMP level.Theresults show that:(1).Oxymatrine can raise the cytoplasmic free calcium.(2).It can also de-crease the cAMP level of PHA preactivated human tonsillar lymphocytes (3).It has no effect oncGMP level of lymphocyte.(4).It has no effect on the calcium uptaking.Combined with ourprevious report,we think that oxymatrine may influence cells' [Ca++] and...

We studied the effects of oxymatine,an alkaloid from Sophra Flavesens Ait,on human andmouse's lymphocytes' cytoplasmic free calcium,calium uptaking,cAMP & cGMP level.Theresults show that:(1).Oxymatrine can raise the cytoplasmic free calcium.(2).It can also de-crease the cAMP level of PHA preactivated human tonsillar lymphocytes (3).It has no effect oncGMP level of lymphocyte.(4).It has no effect on the calcium uptaking.Combined with ourprevious report,we think that oxymatrine may influence cells' [Ca++] and cAMP level via af-fecting cell membrane.

本文研究了氧化苦参碱对淋巴细胞胞浆游离钙、钙摄取功能、cAMP 及cGMP 水平的影响。结果表明:氧化苦参碱可使淋巴细胞浆游离钙水平上升,其钙离子来源于细胞内储存钙的释放。另外,氧化苦参碱可使PHA 活化的人扁桃体淋巴细胞的cAMP 水平降低。我们推测它可能通过某种方式和细胞膜发生作用,从而影响细胞内钙和cAMP 的水平,进而影响细胞功能。

Mean BP, lymphocytic intracellular free Ca2+,plasma Angiotensin Ⅱ. and left ventricular diastolic functionwere determined in patients with essential hypertension(stages Ⅰ, Ⅱ) before and after 4 weeks amlodipine treatment.The results showed: (1)MAP, [Ca2+]i and Ang Ⅱ were significantly reduced after treatment (P<0. 05 ); (2)Ieft ventricular diastolic function (E, A,and E/A ratio) were obviously improved (P< 0. 05 ) ; (3)the decrease in [Ca2+]i was positivelycorrelated with the decrease in MAP (r= 0. 597, P< 0....

Mean BP, lymphocytic intracellular free Ca2+,plasma Angiotensin Ⅱ. and left ventricular diastolic functionwere determined in patients with essential hypertension(stages Ⅰ, Ⅱ) before and after 4 weeks amlodipine treatment.The results showed: (1)MAP, [Ca2+]i and Ang Ⅱ were significantly reduced after treatment (P<0. 05 ); (2)Ieft ventricular diastolic function (E, A,and E/A ratio) were obviously improved (P< 0. 05 ) ; (3)the decrease in [Ca2+]i was positivelycorrelated with the decrease in MAP (r= 0. 597, P< 0. 05);the decrease in Ang Ⅱ was also positively correlated with thedecrease in MAP (r= 0. 454, P<0. 05 ); the descrease in[Ca2+]i was negatively correlated with the increase in E/A ratio (r= - 0. 483,P<0. 05) ; the descrease level of Ang Ⅱ wasalso negatively correlated with the increase level of E/A ratio(r= - 0. 449, P<0. 05 ). It is suggested: the mechanisms ofantihypertensive effect and irnprovernent of left ventricular diastolic function by amlodipine,might be associated to inhibitionon Ang Ⅱ activity and normalization of intracellular calciummetabolism.

测定Ⅰ、Ⅱ期高血压病患者给予氨氯地平治疗四周前后平均动脉压(MAP)、淋巴细胞胞浆游离钙[Ca2+]i、血管紧张素Ⅱ(AugⅡ)及左室舒张功能指标(E,A,E/A)。结果显示:(1)治疗后MAP、[Ca2+]i、AugⅡ显著下降(P<0.05);(2)在室舒张功能指标(E,A,E/A)显著改善(P<0.05);(3)治疗后,[Ca2+]i下降幅度与MAP下降幅度呈正相关(r=0.597,P<0.05);AugⅡ下降幅度与MAP下降幅度亦呈正相关(r=0.454,P<0.05);[Ca2+]i下降水平与E/A比值升高幅度呈负相关(r=-0.483,P<0.05);AngⅡ下降水平与E/A比值升高幅度亦呈负相关(r=-0.449.P<0.05)。提示:氨氯地平的降压和对受损的左室舒张功能改善机理,除通过纠正细胞钙代谢异常外.还可能与其对AngⅡ活性的抑制有关。

 
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