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ad病人
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  ad patients
     Methods Serum were obtained from 45 AD patients and 51 healthy elderly individuals. The titer of anti-Aβ antibodies in serum was m easured using an indirect ELISA.
     方法随机选择AD患者45例和健康老年人51例,①用间接ELISA法测定血清中的抗Aβ抗体滴度,②免疫组织化学ABC法观察AD病人和健康老人血清中的抗Aβ抗体与Tg2576鼠脑内老年斑的结合情况;
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     Studies of AD patients have identified decreased complex IV activity, and some patients with AD and PD have mitochondrial DNA mutations.
     AD病人中 ,线粒体复合酶体 IV活性降低 ,AD、PD病人发现有线粒体 DNA突变 .
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     MethodsThe polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) was used to detect apoE genetype in 25 AD patients and 25 healthy age-matched controls. Meanwhile,The expression of β amyloid precursor protein 16-17exons(App16-17) in peripheral mononuclear blood cells were examined using quantitive competitive RT-PCR methods.
     方法应用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)技术,检测25例AD病人及25例健康老年人的apoE基因型,同时应用相对定量的竞争RNA扩增聚合酶链反应(RT-PCR)技术,检测上述病人外周血单个核细胞中App16-17表达量。
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     Methods 13 AD patients, 10 MCI patients and 10 health volunteers as a control group (HC) were underwent 18F-fluoro deoxyglucose (18F-FDG)-PET scanning.
     方法 对符合入组标准的 13例AD病人、10例MCI病人和 10名健康志愿者 (HC)进行正电子发射计算机断层扫描 (PET)检查测定。
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     Methods:Using MRI-based volumetry techniques and PCR-FRLP,the hippocampal volume and ApoE genotype of 34 AD patients were examined,and the differences of the hippocampal volume between the ApoE ε4 positive AD group(n=17)and the ApoEε4 negative AD group(n=17)were analyzed. The relationship between a number of ApoE ε4 allele and the hippocampal volume has also been evaluated.
     方法 :利用MRI和PCR -FRLP方法对 34例AD病人海马体积和ApoE基因型进行测定 ,比较 17例含ApoEε4基因型和 17例不含ApoEε4基因型AD病人之间海马体积的差异性 ,分析AD病人海马萎缩与ApoEε4等位基因数目间的关系。
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  “ad病人”译为未确定词的双语例句
     Results The MMSE,ADL,SF-36 for patients in early stage and middle stage group were significant higher than that of control groups(P<0.01 and P<0.05);
     结果对两组病人进行MMSE、ADL、SF-36调查,早、中期AD病人实验组MMSE、ADL、SF-36明显高于对照组,差异有显著性意义(P<0.01、P<0.05、P<0.01);
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     Results HPV and HF/CF in AD were less than those in the control group ( P <0.001).
     结果AD病人HPV、HF/CF均小于对照组(P<0.001)。
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     Methods 12 patients with probable AD(age 65.3±8.6 years)and 36 normal controls with matched age and gender(age 65.8±7.4 years) were studied.
     方法研究对象包括12名可能的AD病人[年龄(65.3±8.6)岁]和36例年龄与性别匹配的正常人[年龄(65.8±7.4)岁];
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     Results ①When the patients firstly went to outpatient service, their average age was 76.58± 8. 46 years old ,and the mean course was 2.63±2.04 years .
     结果 ①AD病人首次门诊时的年龄76.58±8.46岁,病程(2.63±2.04)年。
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     Diagnosis of AD was established in 18 of the 33 patients, including 14 male and 4 female patients aged from 20 to 79 years with a mean of 55.8±11.4 years.
     AD病人18例,男14例,女4例,年龄20~79岁,平均年龄(55.8±11.4)岁。
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  相似匹配句对
     Ad.
     Ad.
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     Within 72 h after Ad.
     感染Ad.
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     The Naked Patient
     赤裸的病人
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     The English Patient
     英国病人
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     Donepezil was effective to BPSD in moderate to severe AD.
     多奈哌齐对中、重度AD病人的BPSD有效。
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  ad patients
The APOEallele and genotype frequency distributions were evaluated in 207 AD patients without vascular disorders, 62 AD patients with vascular disorders (combined AD), and 206 control individuals (ethnic Russians from the Russian population).
      
We have analysed serum Hcy and NO levels in AD patients and compared the findings with those in VD patients and control subjects.
      
As regards NO, our results highlight the role of NO as a beneficial molecule in AD and support the use of NO mimetics as an antineurodegenerative therapy for AD patients.
      
The frequency of a single neuropsychological disturbance in early AD patients is illustrated by our own observations.
      
TP perfusion was significantly lower in AD patients than in 18 age-matched, non-demented controls.
      
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21 non-atopic healthy individuals served as control and29 patients with acute atopic dermatitis (AD) were studied by using double-antibody sandwich ELISA for detection of serum IgE. The geometric mean serum IgE level was found to be232 IU/ml in control group, 444 in AD patients with neither family nor personal allergic history, 548 in AD patients with family allergic history and 404 in AD patients with personal a(?)fergic history.The data above indicated that, (1) There was a significant elevation of total serum...

21 non-atopic healthy individuals served as control and29 patients with acute atopic dermatitis (AD) were studied by using double-antibody sandwich ELISA for detection of serum IgE. The geometric mean serum IgE level was found to be232 IU/ml in control group, 444 in AD patients with neither family nor personal allergic history, 548 in AD patients with family allergic history and 404 in AD patients with personal a(?)fergic history.The data above indicated that, (1) There was a significant elevation of total serum IgE in AD patients in comparison with control (P<0.01), (2) The highest serum IgE level was found in patients with family allergic history: (3) There was a tendency that the serum IgE level was roughly related with the severity of skin symptoms: (4) No correlation was found between the serum IgE level and the personal allergic history.

文本用双抗体夹心酶联免疫吸附试验(ELISA)测定了21例无过敏史和寄生虫卵检查阴性的健康对照及29例临床确诊为特应性皮炎(AD)患者的血清总IgE水平。结果表明:(1)AD病人血清总IgE水平明显高于正常对照,经统计学处理差别非常显著(P<0.01);(2)IgE水平与临床症状有呈正相关的倾向,症状严重者IgE水平较高,反之较低,但其差别未达到统计学上有意义的程度;(3)IgE水平与家族过敏史的相关性不明显,具有家族过敏史的AD病人其血清总IgE水平较无家族史者高,但无统计学意义;IgE水平与个人过敏史的关系亦不明显;(4)並非所有AD患者的血清总IgE水平都高于对照组的几何均值,对其可能的原因进行了分析。

We reviewed 64 cases with CT-proven cerebral atrophy, all oceured 1st over 40 years of age. Among them, there were 8 cases of MID. 14 cases of AD. Compared with AD and MID, the course of MID seemed more atypeeal; the ventricular expension of AD demonstrated by CT appeared more prominent. WAIS-RC values of 6 AD and MID matched with age, sex and education suggested that both of them had no significant differences in the whole scaled score, Speech Scaled Score, Operating Scaled Score and each individual test of...

We reviewed 64 cases with CT-proven cerebral atrophy, all oceured 1st over 40 years of age. Among them, there were 8 cases of MID. 14 cases of AD. Compared with AD and MID, the course of MID seemed more atypeeal; the ventricular expension of AD demonstrated by CT appeared more prominent. WAIS-RC values of 6 AD and MID matched with age, sex and education suggested that both of them had no significant differences in the whole scaled score, Speech Scaled Score, Operating Scaled Score and each individual test of AD and MID. However, AD had lowestscore in similarity, then in Digit Symbol and Picture Arrangement. MID showed lower scores in the individual tests of B factor than those in A or B factor, especially, much more lower scores in Picture Arrangement, Picture Completion and Block Design. The results may suggest thar AD have more comprehesible mental dementia than MID, Which have unparallel mental dementia, that is, had poor ability manipulating and motion harmony.

本文收集初发年龄在40岁以后,脑CT证实有脑萎缩患者64例,其中AD14例,MID8侧。两者比较,MID的临床病程经过更不典型,CT显示AD病人的脑室扩大似更突出。6例年龄性别,受教育年限相匹配的AD和MID的WAIS-RC结果显示,两者在全量表,语言量表,操作量表和各分测验量表分间虽无明显区别,但分别对AD和MID的各分测验结果进行分析,表明AD的相似性得分低,其次是数符和图片排列;MID的B因子的分测验得分较A、C因子低,尤其是图片排列,图画填充和木块图案较低,可能提示AD的智能减退更全面,而MID的智能减退不平行,表现为操作和运动协调的能力更差。

AIM: To evaluate the clinical efficacy of Actovegin tablet in treating Alzheimer's disease (AD). METHODS: Sixty_eight patients with mild to moderate AD were recruited. Thirty_four patients (M 17, F 17; age 69±s 8 a) were treated with Actovegin tablet, 400 mg, po, tid for 12 wk and 34 patients (M 24, F 10; age 70±10 a) were treated with placebo (starch) 400 mg, po, tid for 12 wk. RESULTS: Actovegin group showed much higher rates of improvement in cognitive function and clinical global impression than those...

AIM: To evaluate the clinical efficacy of Actovegin tablet in treating Alzheimer's disease (AD). METHODS: Sixty_eight patients with mild to moderate AD were recruited. Thirty_four patients (M 17, F 17; age 69±s 8 a) were treated with Actovegin tablet, 400 mg, po, tid for 12 wk and 34 patients (M 24, F 10; age 70±10 a) were treated with placebo (starch) 400 mg, po, tid for 12 wk. RESULTS: Actovegin group showed much higher rates of improvement in cognitive function and clinical global impression than those of placebo group (P< 0.01). Adverse reactions were mild. CONCLUSION: Actovegin tablet is effective and safe in treating mild to moderate AD patients

目的:评估爱维治片剂治疗轻至中度阿耳茨海默病(AD)的疗效。方法:轻至中度AD病人68例入组,其中34例(男性17例,女性17例,年龄69±s9a)用爱维治400mg,po,tid。另34例(男性24例,女性10例,年龄70±10a)用安慰剂(淀粉)400mg,po,tid。疗程均为12wk。结果:爱维治组在认知功能、临床总体疗效方面改善率均显著高于安慰剂组(P<0.01),爱维治组日常生活功能也较治疗前有明显提高(P<0.01)。该药不良反应轻微。结论:爱维治片剂治疗轻至中度AD有效且安全性好。

 
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