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素性肿瘤
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  “素性肿瘤”译为未确定词的双语例句
     while 6 (14%) were non-melanin tumor,which consisted of 2 metastatic tumor in choroid,1 rhabdomyosarcoma,2 epithelioadenoma of ciliary body,1 plasnoma.
     非黑色素性肿瘤 6例 (14% ) ,其中脉络膜转移癌、睫状体良性上皮腺瘤各 2例、脉络膜横纹肌肉瘤、睫状体浆细胞肉芽肿各 1例。
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     Result:37 of 43 cases (86%) were melanoma,in which 32 of them were derived form choroid,4 from ciliary body; 1 was melanocytoma;
     结果 :4 3例葡萄膜肿瘤中黑色素性肿瘤 37例 (86 % ) ,其中脉络膜黑色素瘤 32例 ,睫状体黑色素瘤 4例 ,黑色素细胞瘤 1例 ;
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     Conclusion:Melanoma is the main type of uveal tumor and most of them are malignant.
     结论 :葡萄膜肿瘤中黑色素性肿瘤为主 ,以恶性肿瘤居多 ,其中黑色素瘤常见。
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  相似匹配句对
     Tumor lymphangiogenesis
     肿瘤淋巴管生成
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     malignant tumor group:I.
     肿瘤组 :I.
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     On Primal Semigroup
     关于素性半群
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     (Urticaria pigmentosa)
     色素性荨麻疹
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     Conclusion:Melanoma is the main type of uveal tumor and most of them are malignant.
     结论 :葡萄膜肿瘤中黑色素性肿瘤为主 ,以恶性肿瘤居多 ,其中黑色素瘤常见。
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PURPOSE:To evaluate the value of the silver-stained nucleolar organizer regions(AgNORs)and computer-assisted image analysis techniques in an attempt to distinguish between bening and malignant or to estimatc prognosis of conjunctival and uveal pigmental tumors. AETH-ODS:The AgNORs and computer-assisted image analysis techniques were performedto detect 44 cases of uveal malignant melanoma, 10 cases conjunctival nevi and 10 cases of conjunctival malig-nant melanomal RESULTS:The AgNORs areas in cnjunctival malignant...

PURPOSE:To evaluate the value of the silver-stained nucleolar organizer regions(AgNORs)and computer-assisted image analysis techniques in an attempt to distinguish between bening and malignant or to estimatc prognosis of conjunctival and uveal pigmental tumors. AETH-ODS:The AgNORs and computer-assisted image analysis techniques were performedto detect 44 cases of uveal malignant melanoma, 10 cases conjunctival nevi and 10 cases of conjunctival malig-nant melanomal RESULTS:The AgNORs areas in cnjunctival malignant melanomas were much higher than those in conjunctival nevi(P<0.05);the AgNORs ares in uveal malignant melanomas increased gradually in order of spindle-cell type,mixed-cell type and epithelial-cell type(P<0.05).CONCLUSION:The AgNORs technique may be helpful in discriminating benign from malignant conjunctival melanomas and in predicting prognosis for uveal malignant melanomas.

目的:评价银染核仁组成区(AgNORs)和计算机图像分析技术在结膜与葡萄膜色素性肿瘤良恶性鉴别诊断或预后评估上的价值。方法:应用AgVORs和计算机图像分析技术对44例葡萄膜恶性黑色素瘤、10例结膜色素滤及10例结膜恶性黑色素瘤进行险测,结果:结膜恶性黑色素瘤较色素痣AgNORs面积显著增加(P<0.05);葡萄膜恶性黑色素瘤AgNORs面积则按梭形细胞型、混合细胞型及上皮样细胞型顺序增加(P<0.05)。结论:AgNORs技术可能有助于结膜黑色素瘤良恶性的鉴别诊断,并可作为葡萄膜恶性黑色素瘤预后评价的参数之一。

The objective of this study is to assess the role of p53 gene mutation in the development and progression of uveal and conjunctival pigmental tumors.We used flow cytometry(FCM)to detect tha p53 gene product expression in uveal malignant melanomas(UMM),conjunctival nevi(CN)and malignant melanomas(CMM).The results showed that the expression content of p53 in 7 cases of CMM was significantly kigher than that in 7 cases of CN(P<0.05).The p53 positive expression percentages in 7 cases of CMM and 39 cases of UMM were...

The objective of this study is to assess the role of p53 gene mutation in the development and progression of uveal and conjunctival pigmental tumors.We used flow cytometry(FCM)to detect tha p53 gene product expression in uveal malignant melanomas(UMM),conjunctival nevi(CN)and malignant melanomas(CMM).The results showed that the expression content of p53 in 7 cases of CMM was significantly kigher than that in 7 cases of CN(P<0.05).The p53 positive expression percentages in 7 cases of CMM and 39 cases of UMM were 71.43% and 66. 67% respectively The p53 expression content(FI)in UMM was significantly associated with DNA index(DI)and DNA ploidy (P<0.01).These indicate thatp53 gene mutation may be an important event in the development of CMM and UMM,and p53 expression content can be used as adjunctive index to distinguish between benign and malignant conjunctival melanomas.Our work provides new biological information to reveal the nature of the development and progression of CMM and UMM.

为评价p53基因突变在葡萄膜与结膜色素性肿瘤发生发展过程中的作用,运用流式细胞术对葡萄膜恶性黑色素瘤(UMM)、结膜色素痣(CN)及恶性黑色素瘤(CMM)的p53基因产物表达进行检测.结果表明:7例CMM较7例CN的p53蛋白表达量明显增高(P<0.05);7例CMM及39例UMM的阳性表达率分别为71.43%,66.67%;UMM的p53蛋白表达量与DNA指数、倍体性密切相关(P<0.01)。提示p53基因突变是CMM与UMM发生过程中的一个重要事件,p53蛋白表达量可作为结膜黑色素瘤良恶性鉴别的辅助指标,为揭示CMM与UMM的发生发展实质提供了新的生物学信息。

Purpose To investigate the clinicopathological features, histogenesis and prognosis of meningeal melanocytoma. Methods Two rare cases of meningeal melanocytoma were reported. The clinical and pathological features of these and 58 other cases in the literature were discussed. Results Two female, aged 14 and 46 years, were found the tumors in the leptomeninges of spinal cord. Both tumors were encapsulated black nodular masses. On microscopic inspection, epithelioid and spindle cells with abundant cytoplasm...

Purpose To investigate the clinicopathological features, histogenesis and prognosis of meningeal melanocytoma. Methods Two rare cases of meningeal melanocytoma were reported. The clinical and pathological features of these and 58 other cases in the literature were discussed. Results Two female, aged 14 and 46 years, were found the tumors in the leptomeninges of spinal cord. Both tumors were encapsulated black nodular masses. On microscopic inspection, epithelioid and spindle cells with abundant cytoplasm were arranged in loose nests. No cellular pleomorphism was seen. Fine melanin granules were in the cytoplasm of the tumor cells in all cases. The mitotic index was zero or one per 10 HPFs. There was no tumor necrosis and hemorrhage. Immunnohistochemical studies of the tumors demonstrated the pressence of HMB45 and S 100 protein. One case of localized lesions in cervical spinal cord was no symptoms of recurrence for 14 months after totally removed. The other case recurred 12 years later and she underwent reoperation of the residual tumor which was found multifocal, although localized at the first time. Conclusions Meningeal melanocytoma is a benign tumor that originates most frequently from the melanocytes in the posterior fossa and spinal cord, with distinct histological and clinical features. Immunohistochemical and electron microscopic studies are very helpful to differentiate meningeal melanocytomas form other melanotic tumors. The importance of differentiating this benign lesion from meningeal malignant melanoma is emphasized. The early surgical removal may result in cure or prolonged remission. The radiation therapy is not effectiveness.

目的 :探讨脑脊膜黑色素细胞瘤的临床病理特征、组织发生及预后。方法 :报道 2例罕见的椎管内软脊膜黑色素细胞瘤(0 0 5 % ) ,并结合国内外文献中报道的 5 8例脑脊膜黑色素细胞瘤进行讨论。结果 :2例均为女性 ,分别为 14岁和 4 6岁 ,肿瘤均发生于脊髓软脊膜 ,大体上呈黑色 ,包膜完整。光镜下见瘤细胞由上皮样细胞和梭形细胞混合而成 ,细胞无异型 ,大部分瘤细胞质内含有多量黑色素颗粒 ,核分裂象无或偶见 (0~ 1个 / 10HPF) ,无出血坏死。免疫表型HMB4 5和S 10 0蛋白呈阳性表达。 1例颈髓单发者全切除术后生存 14个月 ,无肿瘤复发。另 1例开始为颈髓单发性 ,全切除术后 12年复发 ,为颈、胸髓多发性 ,再次行肿瘤部分切除术。结论 :脑脊膜黑色素细胞瘤生物学行为相对良性 ,好发于后颅凹及脊髓的软脑脊膜 ,具有明确的临床和组织学特征。免疫组化和电镜检查有助于本瘤与其他黑色素性肿瘤的鉴别诊断早期完全切除有望治愈或减少复发 ,术后放疗对控制复发并无意义

 
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