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阳性膨体
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  positive varicosity
     ②The population of NGF and NGFmRNA positive neurons, NT-3 positive neurons and neuroglias increased significantly 3d-5d after rhizotomy. However,the quantity and density of positive varicosity of BDNF decreased.
     2去传入后 3~ 5天 ,NGF及其 m RNA阳性神经元数明显增多 ,NT- 3阳性神经元和胶质细胞数也明显增多 ,而 BDNF含量及阳性膨体数却明显减少 ;
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     At 10-11d, the population of NGF and NGF mRNA positive neurons was still on the high level as that at 3-5d, and that of NT-3 began to decrease; the quantity of BDNF recovered to normal except for L 7 segment, but the density of positive varicosity of BDNF did not yet. The mRNAs of BDNF and NT-3 were still negative.
     10~ 11天时 ,NGF及其 m RNA阳性神经元数仍维持高峰水平 ,NT- 3者虽仍高于正常但已有所下降 ,而 BDNF含量除 L7节段外已恢复到正常 ,但阳性膨体数仍未恢复。
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  “阳性膨体”译为未确定词的双语例句
     Conclusion: Partial dorsal root nerve rhizotomy leads to the upregulation of expression of NOS in SG and spinal lamina II.
     结论 :部分背根切断不仅致备用SG胞体偏小的神经元NOS表达增加 ,且II板层NOS的阳性膨体数量亦有增多 .
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     The bFGF immunohistochemical positive neurons and GDNF positive varicosities were also present in spinal laminal II. Both PDGF and bFGF positive ependyma cells were observed around central tube.
     但II板层还可见bFGF阳性细胞和GDNF阳性膨体 ,中央管可见PDGF、bFGF阳性的室管膜细胞。
短句来源
     Results: 1. In rat esophagus, the positive varicosities and fibres could be observed in the circular muscle layer and the muscularis mucosae layer at 21st day before birth. With the development of rat digestive tract, neurokinin A-immunoreactivity(NKA-IR) positive nerves could be observed gradually in the epithelium, submucosa, longitudinal muscle layer, myenteric plexus and submucosal plexes, while mature nerve fibres could be seen at one month after birth.
     结果 1、在食管,于胚胎21天的粘膜肌层和环肌层内观察到神经激肽A免疫阳性膨体纤维,出生后,随幼鼠的生长发育,相继在上皮,粘膜下层,纵肌层、肌间丛、粘膜下丛有NKA-IR表达,30天时已和成年鼠相似;
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     Our results indicated that partial dorsal rhizotomy not only leads to the decrease of BDNF in spinal lamina Ⅱ but also leads to the increase of BDNF in medium and small neurons of spared DRG.
     结果提示 :去背根术后 3 d组脊髓 II板层阳性膨体数的下降及 BDNF含量减少 ,可能是因背根切断导致输入脊髓 II板层的 BDNF中断所致 ;
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     The sections were stained withimmunohistochemicalmethod (BDNF antibody 1∶500,Santa Cruz; NT-3 antibody 1∶1500, Santa Cruz).
     观察BDNF、NT 3免疫阳性反应物在脊髓的分布 ,计数单位面积内Ⅱ板层BDNF阳性膨体密度及NT 3阳性细胞数。
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     The numbers of positive nNOS neurons in various ischemic groups were analyzed statistically a using one - way a
     强阳性
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     nitrate reduction positive;
     反硝化阳性
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     The positively stained fine fibers with varicosities can be spotted , but its connections with neuronal body can not be found .
     可以见到呈阳性反应的细纤维,带有膨体,但其起源不明.
短句来源
     4.The positive distribution of NGF could be seen in the,spinal lamina Ⅰ/Ⅱ of the adult monkey.
     3.NGF阳性神经膨体分布于猴脊髓背角Ⅰ、Ⅱ板层。
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The occurrence and development of neurokinin (NKA) positive nerves in rat esophagus and stomach were observed from 13th day of embryo to adult with the method of PAP immunocy-tochemistry. The results were as follows; (1) In rat esophagus, the positive varicose fibres could be found in the circular muscle layer and the muscularis mucosae layer at 21 days before birth. After birth, NKA-immunoreactivity positive nerves could be found in the epithelium, the longitudinal muscle layer, the myenteric plexus and the...

The occurrence and development of neurokinin (NKA) positive nerves in rat esophagus and stomach were observed from 13th day of embryo to adult with the method of PAP immunocy-tochemistry. The results were as follows; (1) In rat esophagus, the positive varicose fibres could be found in the circular muscle layer and the muscularis mucosae layer at 21 days before birth. After birth, NKA-immunoreactivity positive nerves could be found in the epithelium, the longitudinal muscle layer, the myenteric plexus and the submucosal plexus. With increasing age, the density, thickness, and stain of NKA-I positive nerves increased gradually. Mature nerve fibres could be seen at one month. (2) In rat stomach, the positive reaction of the nerves initially happened in the myenteric plexus, and then the positive fibres appeared in circular muscles, longitudinal muscles and submacosa blood vessels. 30 days after birth, they became well developed. The devolopment of NKA-I positive nerves happened before birth to 4 weeks after birth. In brief, the neruopeptide developed in different positions and in different ways, which shows that NKA has a close relationship with the action of the digestive tract.

应用免疫细胞化学PAP法系统研究了大鼠胚胎13天至成年食道及胃神经激肽A发生发育过程.结果如下:(1)在食道,直至出生前,即胚胎21天才于环肌层及粘膜肌层出现阳性膨体纤维,出生后,随幼鼠的生长发育,相继在上皮内、纵肌层、肌间丛、粘膜下丛出现神经激肽A免疫反应阳性物,其纤维的密度、粗细和着色也逐渐增加,30天时已具备成年的分布特征,其发育主要在生后4周;(2)在胃,于胚胎14天,首先在肌间丛处呈现阳性反应,且发育迅速,阳性反应强,相继在环肌、纵肌、粘膜下层血管壁出现阳性纤维,出生后又于粘膜肌、固有膜及上皮内出现阳性纤维,30天时已和成年鼠的相似,其发育主要在生前1周至生后4周内.提示同一种神经肽在消化道的不同节段其发生不同步,且具不同的发育规律,反映了神经激肽A与消化道的活动有密切的关系.

The hypoglossal nucleus, which innervates extrinsic and intrinsic musculature of tongue and controlls the elaborate and coordinated tongue movement is composed of ventral (protrudor) and dorsal (retractor) Compartments. There is strong evidence that serotonin is an important modulator on oro-facial activity and excitation of hypoglossal motoneurons.In the present study, we studied the topographic distribution of the serotonergic immunoreactivity in rat hypoglossal nucleusby means of PAP imm unohis toe hemis...

The hypoglossal nucleus, which innervates extrinsic and intrinsic musculature of tongue and controlls the elaborate and coordinated tongue movement is composed of ventral (protrudor) and dorsal (retractor) Compartments. There is strong evidence that serotonin is an important modulator on oro-facial activity and excitation of hypoglossal motoneurons.In the present study, we studied the topographic distribution of the serotonergic immunoreactivity in rat hypoglossal nucleusby means of PAP imm unohis toe hemis t ry, and re tractor motone urons us lug a comb ined method. This comb ined me thod inc I udedFast Blue retrograde labeling, intracelluar Lucifer Yellow staining fluorescent immunohistochemistry and con focal laser scanningmicroscopy.The main results were as follows: (1)The serotonergic immunoreactivity was preferentially distributed in dorsal part in caudal hypoglossal nucleus and ventral part in rostral ; (2) Many immunoreactive fibers were derived from caudal pole and coursed along rostrocaudal axis ; (3) Based on the shape and size of the serotonergic varicosities as well as intercourse fibers, three different types of 5-HT a-cons were observed at the light microscopic level: fine fiber with various varicosities, fine fiber with small spindle-like varicosities and coarse fiber with large varicosities ; (4) By simultaneously viewing the morphology of identified neurons with intracelluar staining and serotonergic immunoreactive fibers and terminals, the close appositions were found on the surface of soma, dendritic domain, as well as a-conal hillock in hypoglossal motoneurons ; (5) A similar distribution and density of close appositions were found on genioglossal and styloglossal motoneurons ; these appositions were commonly observed on dendrites 50~100 μm away from soma ; (6) In geniohyoid subdivision, most of the close appositions were found to be aggregated on the surface of soma and proximal dendrites.The results suggested the modulation of serotonin on activity of hypoglossal nucleus is carried out by different selective patterns in different subcompartments. Combined with studies of localization of serotonergic subreceptors on postsynaptic motoneuron, distribution of serotonergic immunoreactive apposition on soma, dendrites and axonal hillock possibly operated differentpostsynaptic mechanisms for excitation activity of hypoglossal motoneurons.

5-羟色胺(5-HT)参与舌和面口部精细运动的调节。5-HT对舌下神经运动神经元功能的调控表现为兴奋性作用。本文首先采用免疫组化方法,在光镜下观察了大鼠舌下神经核内5-HT免疫阳性纤维的形态和分布特征。又进一步采用荧光逆行追踪结合固定脑片细胞内LuciferYellow染色和荧光免疫组织化学染色,通过共聚焦激光扫描显微镜观察了伸舌肌(颏舌肌、颏舌骨肌)和缩舌肌(茎突舌肌)运动神经元与5-HT免疫阳性纤维及其终末的解剖学关系。结果证明:舌下神经核有较丰富的5-HT阳性纤维,以尾侧段的背侧部和吻侧段的腹侧部较为密集;根据纤维及其膨体的形态特征,本文将此阳性纤维分为三种类型。5-HT免疫阳性膨体样纤维及其终末与舌下运动神经元的胞体、树突分枝和轴丘及轴突起始段形成紧密接触;这些接触多呈不均匀的簇状(由2~7个紧密接触点组成)分布。定量分析发现:在额舌肌神经元和茎突舌肌神经元,除少量分布在胞体(密度为3.4~6.7/1000μm2)外,主要分布在近段和中段树突分权处附近;但是在颏舌骨肌神经元则集中分布在跑体(密度为10.8~17.6/1000μm2)和近侧树突上。以上所见提示:5-HT对舌下神经核整体行为的...

5-羟色胺(5-HT)参与舌和面口部精细运动的调节。5-HT对舌下神经运动神经元功能的调控表现为兴奋性作用。本文首先采用免疫组化方法,在光镜下观察了大鼠舌下神经核内5-HT免疫阳性纤维的形态和分布特征。又进一步采用荧光逆行追踪结合固定脑片细胞内LuciferYellow染色和荧光免疫组织化学染色,通过共聚焦激光扫描显微镜观察了伸舌肌(颏舌肌、颏舌骨肌)和缩舌肌(茎突舌肌)运动神经元与5-HT免疫阳性纤维及其终末的解剖学关系。结果证明:舌下神经核有较丰富的5-HT阳性纤维,以尾侧段的背侧部和吻侧段的腹侧部较为密集;根据纤维及其膨体的形态特征,本文将此阳性纤维分为三种类型。5-HT免疫阳性膨体样纤维及其终末与舌下运动神经元的胞体、树突分枝和轴丘及轴突起始段形成紧密接触;这些接触多呈不均匀的簇状(由2~7个紧密接触点组成)分布。定量分析发现:在额舌肌神经元和茎突舌肌神经元,除少量分布在胞体(密度为3.4~6.7/1000μm2)外,主要分布在近段和中段树突分权处附近;但是在颏舌骨肌神经元则集中分布在跑体(密度为10.8~17.6/1000μm2)和近侧树突上。以上所见提示:5-HT对舌下神经核整体行为的调节在不同功能的亚核可能有所选择;5-HT调制舌下运动神经元兴奋性的方式可

Objective To elucidate the postburn change in the activity and the distribution of nitric oxide synthase (NOS) in rat intestinal myenteric plexus . Methods The activity and distribution of NOS were quantitatively and locationally studied by histochemical staining with NADPH-diaphorase(NDP),a marker for NOS,and whole mount preparation technique. Results NOS was widely distributed in whole intestine wall,especially in myenteric plexus.The majority of NOS positive neurons displayed either round or oval...

Objective To elucidate the postburn change in the activity and the distribution of nitric oxide synthase (NOS) in rat intestinal myenteric plexus . Methods The activity and distribution of NOS were quantitatively and locationally studied by histochemical staining with NADPH-diaphorase(NDP),a marker for NOS,and whole mount preparation technique. Results NOS was widely distributed in whole intestine wall,especially in myenteric plexus.The majority of NOS positive neurons displayed either round or oval shape.There were some varicosities string of bead-like structure in the nerve fibers and which were accompanied by blood vessels and muscular fibers.There was no significant postburn change in the density of NOS positive neurons in myenteric plexus(P<0.05).Nevertheless the NOS activity of neurons decreased obviously(P<0.05~0.01).Meanwhile,it was found after injury that there were indistinction of the structure of NOS positive neuron,more breaking of nerve fibers,leading to the lack of integral web of nerve fibers and obvious decrease of NOS positive varicosities in nerve fibers. Conclusion After burn injury,the NOS positive neural structure in myenteric plexus of rat small intestine was damaged with the decrease in NOS activity .Simultaneously,there was impairment of the releasing route of nitric oxide(NO).All these changes might be closely related to intestinal structural damage and dysfunction after burn injury.

目的 探讨烧伤后大鼠小肠壁内一氧化氮合酶 (NOS)的活性及分布的变化规律。 方法 采用NADPH -黄递酶 (NDP)组织化学法和整装铺片技术对烧伤大鼠小肠壁内NOS的活性及分布进行定量和定位研究。 结果 NOS广泛分布于大鼠小肠壁内 ,主要定位于肌间神经丛。NOS阳性神经元多为圆形和卵圆形 ,神经纤维中多含有膨体 ,形成“串珠”样结构 ,且多与血管和肌纤维伴行。烧伤后肌间神经丛中NOS阳性神经元密度变化不显著 (P >0 .0 5 ) ,但神经元内NOS活性则显著下降(P <0 .0 5~ 0 .0 1) ,同时发现烧伤后NOS阳性神经元结构模糊 ,神经纤维断裂较多 ,未能形成完整的神经纤维网 ,神经纤维中NOS阳性膨体亦明显减少。结论 烧伤后大鼠小肠肌间神经丛中NOS阳性神经结构受损 ,神经元内NOS活性下降 ,同时一氧化氮 (NO)的释放途径亦存在障碍 ,这些变化可能与烧伤后肠道结构受损 ,功能障碍密切相关

 
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