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myc阳性
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  myc protein
     The positive rate of bcl 2, c myc protein in gastric carcinoma was significantly higher than that in dysplasia ( P <0.05), especially in Hp positive patients.
     Hp阳性组 bcl- 2、c-myc阳性表达率均高于 Hp阴性组 ,两者之间有显著性差异 (P<0 .0 5)。
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  “myc阳性”译为未确定词的双语例句
     Results In normal colorectal mucosa, colorectal adenoma and carcinoma tissues, hTERT expression rate was 0 0%, 26 2% and 82 8%, C-myc was 0 0%, 33 3% and 70 7%, respectively.
     结果 在正常结直肠粘膜、结直肠腺瘤和结直肠癌组织中 ,hTERT阳性表达率分别为 0 0 %、2 6 2 %和 82 8% ,C myc阳性表达率分别为 0 0 %、33 3%和 70 7%。
短句来源
     Positive staining was seen in 6 cases of c-myc,6 of EGFR,4 of c-erbB-2,2 of N-ras,5 of Rb and 3 of p53. One case was found to be completely positive and 4 completely negative for all the above menitioned oncogene and anti-oncogene products.
     12例中c-myc阳性6例,EGFR阳性6例,c-erbB-2阳性4例,N-ras阳性2例,Rb阳性5例,p53阳性3例。 上述癌基因与抗癌基因产物中,全部阳性的1例,全部阴性的4例。
短句来源
     Results: The results showed that p53 positive was found in 32 cases with gastric cancer (47. 8% ), c-myc positive in 37 caas(55. 2%), P-gp positive in 39 cases (58.2%).
     结果:胃癌中p53阳性32例(478%),c-myc阳性37例(55.2%),P-gp阳性39例(58.2%)。
短句来源
     The positive expression rate of cyclin D1 and c-myc in the colorectal carcinoma were 74.1 % and 70.7 %, respectively, and both of the rates were significantly higher than that of colorectal adenoma (45.2 %, 33.3 %, P < 0. 01, for all).
     大肠癌cyclinD1和C-myc阳性率分别为74.1%、70.7%,均显著高于大肠腺瘤(45.2%,33.3%;P均<0.01)。
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     The positive rate of p16 was negatively correlated with that of c myc in 56 samples(r=-0.997,P< 0.01).
     在56例石蜡标本中p16和c-myc阳性率呈负相关(r=-0.997,P<0.01)。
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     hTERT mRNA was positive expressed judging purple granule in plasma.
     一myc表达均为阳性
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     The protein expres- sion of C--myc gene was notably decreased by PA (0. 625,2. 5mM).
     C-myc 基因胞浆阳性表达显著下降。
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     The incidnece of cardiac events in UAP patients with positive cTnT is high.
     c Tn T阳性
短句来源
     The numbers of positive nNOS neurons in various ischemic groups were analyzed statistically a using one - way a
     强阳性
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     c myc and P53 may play a role in the transcriptive activation of hTERT gene in endometrial carcinoma.
     c myc基因、P
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  myc protein
A decrease in the HL-60 native c-myc protein level wasalso observed with 100 μg/ml of modified antisense ODN, but not with thesense ODN control, by immunoblot analysis.
      
A clone that expressed the v-myc protein was propagated to the end of its life span, with periodic cryogenic storage of the progeny.
      
Molecular analysis showed that the infinite life span cells are, indeed, derived from the cells used for transfection, and that they continue to express the v-myc protein.
      
We further examined the effect of FR901228 on c-myc protein, which is one of the main hTERT transcription activators.
      
FR901228 repressed c-myc protein only in the absence of CHX, and depended on the enhancement of de novo protein synthesis.
      
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The expression of C-myC oncogene was studied at the protein level incells obtained from 10 patients with leukemia. Expression of C-myConcogene in 4 patients without remission was much higher than thatin other 3 patients with remission. 2 cases was examined who had beenremission in clinic and in amount of bone marrow blast cells but whoseexpression of C-myC and the amount of C-myC positive cell was stillkeeped at high level. They had relapse after lmonth. this data suggestedthat expression of C-myC oncogene in...

The expression of C-myC oncogene was studied at the protein level incells obtained from 10 patients with leukemia. Expression of C-myConcogene in 4 patients without remission was much higher than thatin other 3 patients with remission. 2 cases was examined who had beenremission in clinic and in amount of bone marrow blast cells but whoseexpression of C-myC and the amount of C-myC positive cell was stillkeeped at high level. They had relapse after lmonth. this data suggestedthat expression of C-myC oncogene in protein level could predictwhether leukemia relapse in future as more susceptible indicater thanthat in the bone marrow morphology. In other hand amount of C-myCpositive cells in bone marrow of all 10 cases was more than that ofblast cells, suggesting that some leukemic cells which can not bedetectable in morphology of cells can be detected.

本文检测10例白血病C-myC癌基因在蛋白质水平上的表达,发现4例不缓解白血病的C-myC阳性细胞百分比以及C-myC总的表达量明显高于缓解期病人的表达,2例病人临床及骨髓象已达缓解,但C-myC蛋白阳性细胞百分数及C-myC蛋白总表达量仍维持高水平表达,分别于28天及37天复发。这提示,C-myC蛋白的表达水平是预示白血病复发的更敏感的指标。另外,10例白血病病人的C-myC阳性细胞百分数均较骨髓内幼稚细胞百分数为高,提示一部分形态上看来是正常的细胞,仍有C-myC的表达,这部分细胞很可能是白血病细胞。

We have studied the co-expression of the c-neu, c-myc and P53 oncogene proteins in colorectal carcinomas from 103 cases, using an immunohistochemical method. Strong staining was found in 42.7% of tumors for c-neu, 39.8 % for c-myc and 13.5% for P58. No statistical difference was found in positive rates between c-neu and c-myc, suggesting a similar importance in the initiation and progression of human colorectal carcinoma. In the 14 out of the 103 cases observed, P53 was in co-expression with c-neu or c-myc....

We have studied the co-expression of the c-neu, c-myc and P53 oncogene proteins in colorectal carcinomas from 103 cases, using an immunohistochemical method. Strong staining was found in 42.7% of tumors for c-neu, 39.8 % for c-myc and 13.5% for P58. No statistical difference was found in positive rates between c-neu and c-myc, suggesting a similar importance in the initiation and progression of human colorectal carcinoma. In the 14 out of the 103 cases observed, P53 was in co-expression with c-neu or c-myc. No positive staining of P53 was seen alone in any of the 103 cases. The positive rate of P53 was significantly different (P<0.01) from c-neu, and c-myc.

应用免疫组织化学的方法,研究103例结、直肠癌的c-neu、c-myc和P53癌基因蛋白的共同表达。103例中c-neu强阳性为42.7%,c-myc为39.8%,P53为13.5%。前两者之间的阳性率无显著差别,表明这两个癌基因在结、直肠癌的发生发展中具有相同的重要性。在103例中,14例的P53是与c-neu或c-myc共同表达的,无一例P53单独表达阳性。P53与c-neu,P53与c-myc的阳性率均有显著的统计学上差别(P<0.01)。

Objective : The authors investigated the expression of c-myc and N-ras mRNA in 21 cases paraffin-embedded tissue sections of hepatocellular carcinoma(HCC). Metbods : In situ hybridization technique withbiotinylated cDNA probes was used. Results: The results showed c-myc mRNA to be positive in 9 cases(42.9%)and N-ras positive in 4 cases(19%)in the hepatoma cells. Four cases and 1 case, in the peritumorhepatocytes, were slightly positive for c-myc and N-ras respectively.C-myc and N-ras mRNAs were localizedwithin...

Objective : The authors investigated the expression of c-myc and N-ras mRNA in 21 cases paraffin-embedded tissue sections of hepatocellular carcinoma(HCC). Metbods : In situ hybridization technique withbiotinylated cDNA probes was used. Results: The results showed c-myc mRNA to be positive in 9 cases(42.9%)and N-ras positive in 4 cases(19%)in the hepatoma cells. Four cases and 1 case, in the peritumorhepatocytes, were slightly positive for c-myc and N-ras respectively.C-myc and N-ras mRNAs were localizedwithin cytoplasms of both hepatoma cells and peritumor hepatocytes. However, the positive intensities of c-myc and N-ras mRNA were much greater than those in the peritumor hepatocytes. Conclusion : The resultsindicated that c-myc and N-ras oncogenes were overexpressed in HCC, and got involved in the hepatocar-cinogenesis and interfered in the transduction of signals in the hepatocytes of HCC and may play an importantrole in coordinatively maintaince of the malignant phenotypes in HCC.

应用生物素标记的c-myc,N-rascDNA探针对21例肝细胞癌石蜡切片进行原位杂交研究,结果显示,在21例肝癌组织中9例呈c-myc阳性(42.9%),4例为N-ras阳性(19%),而癌旁肝组织中仅有4例呈c-myc弱阳性,1例呈N-ras弱阳性.C-myc,N-ras,mRNA多分布于肝癌细胞胞浆中,显微分光光度计检测结果显示,肝癌细胞中c-myc,N-ras,mRNA阳性信号明显高于癌旁肝细胞.作者认为,c-myc,N-ras癌基因在肝细胞癌中均可呈较高水平表达.二者参与了肝癌的恶性转化过程并在肝癌的发生过程中相互协同以维持肝癌的恶性表型.

 
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