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瘤作用
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  tumor effect
     The in vivo anti tumor effect of ampelopsin was evaluated by observation of growth inhibition of B16 melanoma inoculated into C57BL/6 mice.
     观察蛇葡萄素对C57BL/6小鼠移植性B16黑色素瘤的体内抑瘤作用;
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     Objective To study the CTL induced by HSP 70 peptides of S 180 cells and its anti tumor effect in vitro.
     目的 探讨鼠S1 80 细胞HSP 70多肽诱导杀伤性T淋巴细胞 (CTL)及其特异性抗瘤作用机制。
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     In vivo , the two genes treatment and the single gene IL 2 or IFN γ treatment showed more significant anti tumor effect and higher specific CTL activity after the intratumoral injection of the Dosper DNA complexes as compared with the LacZ gene treatment.
     直接瘤内注射 Dosper- DNA复合物后 ,与对照组 ( Lac Z)相比 ,双基因组及 IL- 2或 IFN-γ单基因组均产生了较明显的抗瘤作用 ,并诱发了较高的特异 CTL活性 .
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     Chnclusion: The anti -- tumor effect of TNF can be enhanced in the presece of DOX, suggestion that the addition of DOX may interfere with the cellular protective mechanism, causing the tumor cells to become rae susceptible to the cytotoxic action of TNF.
     结论:DOX存在时,TNF的抗瘤作用增强,从而支持DOX可干扰细胞保护机制以使瘤细胞对TNF细胞毒作用更为敏感的理论。
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     Conclusion NDV appears to replicate in human lung adenocarcinoma xenografts,leading directly to a potent anti tumor effect after once injection of live NDV.
     结论 NDV对裸小鼠人肺腺癌移植瘤有明显地抑瘤作用。 其抑瘤作用与NDV选择性地在肿瘤细胞内增殖并导致肿瘤细胞凋亡及溶解肿瘤细胞有关。
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  “瘤作用”译为未确定词的双语例句
     Study on the Expression of Fas/FasL in Human Gliomas and the Inhibitory Effect of FasL cDNA on the Growth of Glioma Cells in Vitro as Well as in Vivo
     人脑胶质瘤Fas/FasL基因表达及FasL cDNA体内外抑瘤作用的研究
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     Study on the Gene Expression of Vascular Endothelial Growth Factor (VEGF) & Its Receptors in Human Hepatocellular Carcinoma and the Inhibitory Effect of Antisense VEGF RNA on the Growth of Liver Cancer Cell in Vivo & in Vitro
     人肝细胞癌血管内皮生长因子及受体基因表达和其反义RNA体内外抑瘤作用的研究
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     Experimental Study on Expression of pEgr-p16 and the Role of Anti-tumor Induced by Ionizing Radiation
     辐射诱导pEgr-p16的表达及抑瘤作用的实验研究
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     Study on the Expression of EGFR and p53 in Human Gliomas and the Inhibitory Effect of EGFR Antisense RNA Combined with p53 Gene on the Growth of Glioma Cells
     人脑胶质瘤EGFR和p53基因表达以及EGFR反义RNA与p53基因联合转导对胶质瘤生长抑瘤作用的研究
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     Study on the Gene Expression of Vascular Endothelial Growth Factor (VEGF) in Human Esophageal Carcinoma and the Inhibitory Effect of Antisene VEGF RNA on the Growth of Esophageal Cancer Cell in Vivo & in Vitro
     人食管癌组织血管内皮生长因子基因表达和其反义RNA体内外抑瘤作用的研究
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  相似匹配句对
     Antitumor Effect of Anuoning
     阿诺宁的抗作用研究
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     EXPERIMENTAL STUDIES ON THE CANCER PREVENTION EFFECT OF SELENIUN
     硒抑作用的实验研究
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     Affect of Role Intrusion Detection System
     入侵检测系统的作用
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     /L.
     /L)的作用
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     Glomus Tumor
     血管球
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  tumor effect
Ehrlich's ascites carcinoma-bearing mice were used to investigate the anti-tumor effect of BBSKE in vivo.
      
The anti-tumor effect of human LAK cells in nude mice may offer a useful model to study the role of human LAK cells against human tumorin vivo.
      
Experimental study of anti-tumor effect of electrochemical therapy alone or in combination with radiotherapy
      
Objective: To improve the preparation of adherent lymphokine-activated killer (A-LAK) cells and study the synergistic anti-tumor effect of phenylacetate (PA) and A-LAK cells.
      
Conclusion: A-LAK cells could be simply prepared by using PME, and showed a synergistic anti-tumor effect with the combination of PA.
      
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This Paper is a study of segragation and purification from the

云芝[polysictus Versicolor(L.)Fr.]是一种多孔菌科真菌。从野生云芝子实体中提取的“云芝多糖”治疗慢性肝炎,近期总有效率可达80%以上,现已鉴定通过。国外已有较多报导,云芝多糖具有抑瘤作用,其子实体和菌丝发酵产物提取的多糖体,可提高机体的免疫功能。为满足大规模工业化生产的需要,东北师大生物系抗癌药物研究室,在实验室研究的基础上,又与长春制药厂协作,进行了云芝深层发酵的中间试验,现已试验结束,制定出具体的工艺流程。本工艺方法较简便、生产周期短、原料价廉、收率较高、适合工业化生产。

Inhibition of polysaccharides on sarcoma 180 and the immune response of polys-accharides werestudied.

本文对云芝菌体多糖(PV-1)及滤液多糖(PV-4)作了抗肿瘤及对免疫功能的影响等实验研究。结果,两种多糖均使小鼠胸腺缩小,脾重增加,并有提高巨噬细胞吞噬的作用。但抑瘤作用较弱。PV-1能增强戊巴比妥钠的作用,使小鼠睡眠时间延长。两种多糖毒性均很小,小鼠腹腔注射 LD50 PV-1为2750mg/kg,PV-4为2883mg/kg。

Radix Trichosanthis injection,in addition to its use as an abortifacient drug of mid-pregnancy,is also used to abort early pregnancies.The inhibitory effect of this drug onthe deciduoma was considered to be an important mechanism of abortive effect in earlypregnancy.It is well known that the regulatory effects of sex hormones on the decidual re-action are related not only to the blood concentrations but also to the amount of hormonalreceptors in the target organs and to the affinity constant(K_A)between the...

Radix Trichosanthis injection,in addition to its use as an abortifacient drug of mid-pregnancy,is also used to abort early pregnancies.The inhibitory effect of this drug onthe deciduoma was considered to be an important mechanism of abortive effect in earlypregnancy.It is well known that the regulatory effects of sex hormones on the decidual re-action are related not only to the blood concentrations but also to the amount of hormonalreceptors in the target organs and to the affinity constant(K_A)between the receptors andthe sex hormone.The effects of Radix Trichosanthis injection on the progesterone receptor(PgR)andestradiol receptor(ER)of the deciduoma of pseudo-preganant mice were studied,using aradioreceptor assay which measured the cytoplasmic PgR and ER of the deciduoma in termsof fmol per mg protein.The corresponding affinity constants(K_A)were then obtained bymeans of Scatchard plots.It was found that,after a subcutaneous injection of Radix Trichosanthis 5 mg/kg onthe 7th day of pseudopregnancy,the weight of the deciduoma showed no marked decreasewhen compared with that of the untreated group,and neither did the amount of cytoplasmicER decrease,although the amount of cytoplasmic PgR did decrease significantly.Aftertwo successive subcutanious injections of the aforesaid dose of Radix Trichosanthis on the6th and 7th day of pseudopregnancy,the weight of the deciduoma and the amounts of cyto-plasmic PgR and ER all decreased significantly.The affinity constant(K_A)of cytoplas-mic ER of the deciduoma,however,was not altered by a subcutaneous injection of RadixTrichosanthis on the 7th day,but after two successive injections of drug on the 6th and7th day of pseudopregnancy,this variable declined slightly and maintained the level of10~9M~(-1).By contrast,the K_A of cytoplasmic PgR showed a significant decrease and thisKA was so much reduced as to be hardly measurable,proportionately to the dose of RadixTrichosanthis injection.These experimental results suggest that the inhibitory effects of Radix Trichosanthison cytoplasmic PgR and ER of the deciduoma and the diminution of the affinity constants(K_A)of the two sex hormonal receptors,especially that of cytoplasmic PgR,by Radix Tri-chosanthis bring about the disordered regulation of the decidual reaction by sex hormones.This may be the important mechanism of the inhibitory effect on the deciduoma of RadixTrichosanthis injection.

本文采用放射受体法测定蜕膜瘤胞浆内孕酮受体和雌二醇受体,以fmol/mg 蛋白表示其量,并作Scatchard plot 求其结合常数(K_A)。观察天花粉对假孕小鼠蜕膜瘤孕酮受体和雌二醇受体的影响。在假孕第7天皮下注射天花粉5毫克/公斤/日,蜕膜瘤重量及胞浆内雌二醇受体量及其K_A 与对照组相比无显著差异,但胞浆内孕酮受体量及其真K_A 值则已显著下降。在假孕第6、7二天连续皮下注射同量天花粉,蜕膜瘤重量、胞浆内孕酮受体量、雌二醇受体量及其K_A 均显著下降。而孕酮受体的K_A 值已难以测出。上述结果提示,天花粉减少蜕膜瘤胞浆内孕酮受体和雌二醇受体,并使受体的K_A值(尤其是孕酮受体K_A)变小,从而减弱了激素对蜕膜反应的调节作用,这可能是天花粉抑制蜕膜瘤作用的一重要机制。

 
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