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肾小球硬化
相关语句
  glomerulosclerosis
    Effects of urokinase on the experimental chronic glomerulosclerosis in rats
    尿激酶防治大鼠实验性肾小球硬化慢性肾衰的疗效观察
短句来源
    From needle pathology,the patients were divided into obesity-related focal and segmental glomerulosclerosis(O-FSGS) and obesity-related glomerulomegaly(O-GM) group.
    根据肾活检组织学改变分为肥胖相关性单纯性肾小球肥大(obisity-related glomerulomegaly,O-GM)和肥胖相关性局灶节段性肾小球硬化(obisity-related focal and segmentalglomerulosclerosis,O-FSGS)。
短句来源
    (2) The main pathological characteristics of the 263 FSGS cases were as follows: 48.4% of the patients had a glomerulosclerosis ratio more than 25% , 88.5% of glomerulosclerosis usually accompanied tubulointerstitial lesion, including severe lesions of graded 2 or 3 (about 25.2%).
    (2)主要病理特征: 48.4%患者肾小球硬化比率≥25%,肾小球硬化并伴有肾小管间质病变者占88.6%,其中伴严重肾小管间质病变占25.2%。
短句来源
    A positive correlation was also found between glomerulosclerosis and tubulointerstitial lesion (P<0.01).
    肾小球硬化程度与小管间质病变程度呈正相关(P<0.01),与血浆门蛋门水平呈正相关(P<0.05)。
短句来源
    The relationship between lessening of glomerulosclerosis by enalapril and apoptosis of glomerular cells
    依那普利减轻肾小球硬化及与肾小球细胞凋亡的关系
短句来源
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  glomerular sclerosis
    The relationship between glomerular sclerosis and the change of extracellular matrix
    肾小球硬化与系膜基质改变的关系
短句来源
    Effect of Fluvastatin on PAI-1 and Collagen Type Ⅳ in Rats of Glomerular Sclerosis
    氟伐他汀对肾小球硬化大鼠纤维蛋白溶解酶原激活物抑制剂-1和Ⅳ型胶原的影响
短句来源
    Effect of prostaglandin E_1 on renal expression of HGF in glomerular sclerosis in rats
    前列腺素E_1对肾小球硬化大鼠肾组织肝细胞生长因子的调节
短句来源
    Effect of Fluvastatin on Collagen Type Ⅳ and Molecular Mechanism in Rats of Glomerular Sclerosis
    氟伐他汀对肾小球硬化大鼠Ⅳ型胶原的影响及分子机制研究
短句来源
    Glomerular Sclerosis and Angiotensin Ⅱ Receptor Antagonist
    肾小球硬化及血管紧张素受体拮抗剂的应用
短句来源
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  “肾小球硬化”译为未确定词的双语例句
    [Conclusion] Recombinant TGF-β1 antisense eukaryotic expression vector can inhibit the secretion of FN and PAI-1, which may be effective in gene therapy for sclerosing glomerulonephritis and proliferative glomerulonephritis.
    结论反义TGF-β1基因真核表达载体可从分子水平阻断MsC的FN及PAI-1表达,在肾小球硬化及肾小球肾炎的研究治疗中有一定的应用价值。
短句来源
    The renal interstitial inflammation may promote the apoptosis in the remnant kidney.
    结论:细胞凋亡参与肾小球硬化、肾小管萎缩及间质纤维化的过程,肾间质炎细胞的浸润更促进残肾凋亡的发生。
短句来源
    Effect of Fluvastatin on Collagen Type Ⅳ in Rats of Glomeru lar Sclerosis
    氟伐他汀对肾小球硬化大鼠Ⅳ型胶原的影响
短句来源
    NPHS2 mutation (431C>A) in a nephrotic patient with focal and segmental glomerulonephrosis
    局灶节段性肾小球硬化与NPHS2基因突变
短句来源
    Expression and implication of tissue transglutaminase in FSGS model rats with puromycin aminonucleoside nephropathy
    组织型转谷氨酰胺酶在局灶节段性肾小球硬化大鼠肾脏中的表达和意义
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  glomerulosclerosis
However, the pathologic lesions of focal segmental glomerulosclerosis in experimental models of sustained obesity, and in obese humans presenting with massive proteinuria, are different from those of classic diabetic nephropathy.
      
Among the multiple glomerulopathies that can affect patients with HIV, focal segmental glomerulosclerosis (FSGS) is most common and frequently leads to end-stage renal disease.
      
Frequently, ensuing focal and segmental glomerulosclerosis may well be related to alterations in intraglomerular hemodynamics and may result in heavy proteinuria.
      
Factors for the occurrence of segmental glomerulosclerosis have been assessed in animal models and include the influence of lipids.
      
Drugs of this class fairly uniformly reduce glomerulosclerosis, delay the deterioration in renal function, and improve proteinuria, a predictive surrogate marker for renal injury.
      
更多          
  glomerular sclerosis
In the 8th week of the experiment, the ET level was further elevated and pathological study demonstrated local glomerular sclerosis and infiltration of lymphocytes of interstitia.
      
It is concluded that the NS patients had the potential risk of suffering from coronary artery disease, glomerular sclerosis and thrombosis.
      
It suggested that the inhibitory effect of heparin on diabetic glomerular sclerosis was at least partly related with the inhibition of TGF-β1 expression.
      
The rats in the model group developed glomerular sclerosis and renal interstitial fibrosis.
      
The present work deals with the hypothesis that probucol, through its antioxidant properties, may be a useful tool in the prevention of age-related glomerular sclerosis.
      
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The clinical and pathological features of 307 patients of primary ■glomerulonephritis

本文对307例经肾活检有完整资料的原发性肾小球肾炎患者的临床及病理类型进行分析,从而探讨它们之间的关系。结果:肾小球肾炎10种主要病理类型的分布以系膜增殖性肾小球肾炎居首位,占30.9%,其次为IgA 肾病(18.9%)及局灶性节段性肾小球硬化(14.7%);男女性分别占74.3%及25.7%;各型中患病平均年龄以膜性肾病(37.6岁)为最大;肾病综合征最常见于膜性肾病,占66.67%;反复发作性肉眼血尿则以IgA 肾病居多;40.00%的局灶性节段性肾小球硬化发生高血压;肾功能减退最明显的是局灶硬化和IgA 肾病。实验室检查有助于判断肾小球、肾小管和间质病变的轻重。本文探讨了微小与非微小病变的计算机分型,其分辨率可达90%以上。

The Pathologic data of normal human kidneys were reviewed.Subjects ranged in age from 8 months to 83 years and were divided into 4 gronps on the basis of 20 years Total subjects were examinated under light microscope.12 cases totality were also studied under electron microscope Results showed that with ageing,the rate of glomerulosclerosis were increased and glomerular basement membrane were thickened,the thickness of the basement membrane of the loop of Henle were increased.We found that the number of the disklike...

The Pathologic data of normal human kidneys were reviewed.Subjects ranged in age from 8 months to 83 years and were divided into 4 gronps on the basis of 20 years Total subjects were examinated under light microscope.12 cases totality were also studied under electron microscope Results showed that with ageing,the rate of glomerulosclerosis were increased and glomerular basement membrane were thickened,the thickness of the basement membrane of the loop of Henle were increased.We found that the number of the disklike bodies in the basement mambrane of the loop of Henle increased with age. These changes were sigmificant statistically.The latent renal changes in the elder indicated that renal function decreased with ageing.for diagnosis treatment and diet,we must consider the renal functinn in the elderly

本文对103例正常肾脏进行了病理分析,年龄在8个月至83岁,按20岁一组分为4组,对各年龄组的肾脏作了光镜检查,12例做了电镜研究。结果表明:随年龄的增长,肾小球的硬化率增加,肾小球的基底膜增厚,亨利氏袢的基底膜增厚。亨利氏袢基底膜上的盘状小体的数目随年龄的增长有增加的趋势。以上各种变化均有统计学意义。这些老年肾脏潜在性变化,说明随年龄的增长肾功能逐渐减退。

57 oases aged over 50 (elderly group) with Biopsy-proven renal diseases were analysed in regards to their clinical and pathologic presentation as compared with 593 cases aged under 50 (younger group) with renal disease also biopsied during the same period of time.Results showed that the incidence of primary glomerular disease was lower in the elderly group (64.9 vs 59.9%)in which membranous nephropathy(MN)was the most frequent glomerulonephropathy occupying 39.4% arid its inoidenoe was higher than that in the...

57 oases aged over 50 (elderly group) with Biopsy-proven renal diseases were analysed in regards to their clinical and pathologic presentation as compared with 593 cases aged under 50 (younger group) with renal disease also biopsied during the same period of time.Results showed that the incidence of primary glomerular disease was lower in the elderly group (64.9 vs 59.9%)in which membranous nephropathy(MN)was the most frequent glomerulonephropathy occupying 39.4% arid its inoidenoe was higher than that in the younger group (14.8%, p<0.01), however, IgA nephropathy (6.1 vs14.8%),intercapillary proliferative GN (IPGN) (O vs 6.2%) as well aa focal glomerular sclerosis (FGS) (O vs 5.3%) were less frequent (p<0.05). Glo-merular diseases secondary to diabetes (14.0 vs 3.2%), amyloidosis nephropathy (3.5 vs 0%) were higher in the elderly group (p<0.05) and lupus nephritis (5.3 vs 18.9%) was lower in the elderly. The inoidenoe of interstitial nephritis in these two groups were 10.5 and 2.7%, respectively.MN was the most common pathologic basis for the nephrotio syndrome seen in the elderly group which always had a higher inoidenoe of glomerular sclerosis. Interstitial fibrosis and fibromuscular hyperplasia in renal arterioles. 3 oases were found to be associated with malignancies. The other clinical characteristics of MN in the elderly included: higher incidence of hypertention, lower CCr, lower selectivity index in proteinuria and poorer response to steroid and/or immunosuppresive therapy.The mechanisms related to these pathologic and clinical manifestat tion in elderly group of renal diseases were discussed.

经肾穿刺明确诊断的50岁以上肾脏病者57例,与同期50岁以下的593例肾活检病例比较,前者膜性肾炎明显多见(P<0.05),其特征为肾小球硬化率较后者为高,间质纤维化和血管病变较严重,高血压多见,肾功能相对较差(p<0.05)。50岁以上组有3例伴癌肿、2例伴下腔和肾静脉血栓形成。间质性肾炎和糖尿病性肾病的发生率也明显较高。

 
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