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胞浆钙
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  intracellular calcium
     The aim of this study was to elucidate modulation of intracellular calcium homeostasis byinteraction between hydrogen peroxide(H_2O_2)and the sodium-calcium exchange protein in theplasma membrane.
     本研究旨在阐明过氧化氢(H_2O_2)和膜钠钙交换蛋白相互作用对胞浆钙〔Ca ̄2+〕_i的调控。
短句来源
     5) Tetrandrine 1 and 10 μmol·L-1 could apparently inhibited Ca2+ release from intracellular calcium stores induced by caffeine 20 mmol · L-1 (P < 0.05).
     (5)在无钙细胞外液中,粉防己碱1和10μmol·L~(-1)可明显抑制咖啡因20mmol·L~(-1)引起的胞浆钙升高(P<0.05)。
短句来源
     Effects of Cordyceps sinensis on intracellular calcium concentration and L-type calcium current of ventricular mytocytes in guinea pig
     冬虫夏草对豚鼠心室肌细胞胞浆钙离子浓度及L-型钙电流的影响
短句来源
     Conclusion: At high concentration, EM and GM elevated intracellular calcium which may be related to their nephrotoxicity.
     结论:爱大霉素和庆大霉素在较高浓度时可使胞浆钙升高,这可能与其产生肾毒性有关
短句来源
     The effects of different concentrations of norepinephrine,vasopressin,and ATP on intracellular calcium concentration ([Ca~(2+)])increases in the freshly isolated rat hepatocytes were investigated. [Ca~(2+)]; was measured by micro-fluorometry and recorded as fluorescence ration(F_(340)/F_(380)).
     分离的肝细胞加载钙离子荧光指示探针Fura-2,通过显微荧光术测量胞内钙浓度的变化,以荧光比例(F_(340)/F_(280))表示,分别检测不同浓度范围的去甲肾上腺素、加压素、ATP对单个肝细胞胞浆钙离子浓度升高的作用.
短句来源
  cytoplasmic calcium
     Changes of Erythrocytic Cytoplasmic Calcium System in the Newborn of Hypoxic-ischemic encephalopathy
     缺氧缺血性脑病新生儿红细胞胞浆钙系统的变化及分析
短句来源
     The results showed that platelet cytoplasmic calcium was significantly increased in the stroke patients as compared with controlsmol/L,control group (2.010.31)mol/L,P<0.001].
     结果表明,脑梗塞组血小板胞浆钙离子浓度明显高于对照组,脑梗塞组是(2.87±0.35)μmol/L,对照组是(2.01±0.31)μmol/L,两组间有极显著差异(P<0.001)。
短句来源
     Results A23187 caused an increase in cytoplasmic calcium,loss of cell viability,and DNA fragmentation in PC12 cell line.
     结果钙载体(A23187)升高PC12胞浆钙离子,降低细胞存活率,DNA琼脂糖电泳显示典型的DNA梯形带。
短句来源
     Neuronal apoptosis and cytoplasmic calcium
     神经细胞凋亡与胞浆钙离子
短句来源
     Effect of Shenmai Injection on Neurocyte Apoptosis and Change of Cytoplasmic Calcium
     参麦注射液对神经细胞凋亡及胞浆钙变化的影响
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  “胞浆钙”译为未确定词的双语例句
     24 hours after incubation, the [Ca~2+] in plasma (16.81±2.1)was significantly elevated compared with control group(7.45±1.96)(P<0.01), and the [Ca~2+] in nuclear(30.65±4.06)was also distinctly increased compared with control group(15.64±2.16)(P<0.01).
     经100nmol/LNPY刺激24h后,心肌细胞胞浆钙含量(16.81±2.1)明显高于对照组(7.45±1.96)(P<0.01),核内钙含量(30.65±4.06)也显著高于对照组(15.64±2.16)(P<0.01)。
短句来源
     To study the effect of nicardipine (Nic) on the cytoplasmic free calcium concentration ([Ca2+];)
     研究尼卡地平(nicardipine,Nic)对小鼠胸腺细胞胞浆钙浓度([Ca~(2+)]_i)及增殖的影响.
短句来源
     Objective: To observe changes of cytosol free Ca2+ and mitochondrial Ca2+ concentration inbrain cells of neonatal rats after hypoxic-ischemia and intervention of MK-801, magnesium sulfate andphenobarbiturate.
     目的:了解缺氧缺血后新生鼠脑细胞胞浆及线粒体Ca2+浓度的动态变化及MK-801、硫酸镁、苯巴比妥钠干预对胞浆钙超载的影响。
短句来源
     Effects of AG 555 on Cytosolic Free Calcium in Pig Platelets
     AG555对猪血小板胞浆钙离子浓度的影响
短句来源
     In calcium-free Tyrode's solution, low-dose of AS2O3 had no effects on the [Ca2+ ];
     在无钙台氏液中,低浓度As2O3对胞浆钙无影响,高浓度的As2O3引起持续钙增高。
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  intracellular calcium
We studied the effects of the chelating agents of extra- and intracellular calcium ions, EGTA and BAPTA-AM, and of the inhibitor of Ca2+release from the reticulum, TMB-8, in the kinetics of protein synthesis in hepatocyte cultures.
      
However, exogenous gangliosides in the dense or diluted cultures preincubated in the presence of BAPTA-AM ore TMB-8 allowed the rhythm visualization, i.e., synchronization may not depend on changes in the intracellular calcium concentration.
      
Elevation of intracellular calcium level is responsible for activation of ROS-generating enzymes and formation of free radicals by the mitochondria respiratory chain.
      
On the other hand, an increase in intracellular calcium concentration may be stimulated by ROS.
      
Unlike FXa, thrombin induced transient intracellular calcium signal in hippocampal neurons, which was mainly mediated via IP3 receptors of the endoplasmic reticulum.
      
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  cytoplasmic calcium
Disturbed Cooperation of Hepatocytes in the Rhythm of Protein Synthesis by Chelating Agent of Cytoplasmic Calcium BAPTA-AM
      
The synchronized oscillations of the protein synthesis rate in dense hepatocyte cultures were blocked 30 min after their treatment with 10-20 μM BAPTA-AM, a chelating agent of cytoplasmic calcium.
      
Influence of ATP on Ehrlich ascites carcinoma cell free cytoplasmic calcium concentration in the course of tumor growth
      
The changes in free cytoplasmic calcium concentration ([Ca2+]in) and the effects of extracellular ATP on [Ca2+]in have been studied in Ehrlich ascites carcinoma cells in the dynamics of their growth.
      
A theoretical model of calcium signaling is presented that simulates oscillations of cytoplasmic calcium concentration ([Ca2+]cyt) in stomatal guard cells under the action of abscisic acid.
      
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In this paper, the immunoregulatory effects of calcium ionophore A23187 on the accessory function of mouse spleen dendritic cells (DC) in primary mixed lymphocyte reaction (1'MLR) and oxidative mitogenesis are reported. A23187 had a direct enhancing effect on DC. When pretreated with 0.5-1μmol/L A23187 for 6-8 h, the accessory activity of DC was twice as high as that of the control. This is circumstantial evidence indicating an up-regulation of activity mediated by an increase in intracellular Ca2+ levels and...

In this paper, the immunoregulatory effects of calcium ionophore A23187 on the accessory function of mouse spleen dendritic cells (DC) in primary mixed lymphocyte reaction (1'MLR) and oxidative mitogenesis are reported. A23187 had a direct enhancing effect on DC. When pretreated with 0.5-1μmol/L A23187 for 6-8 h, the accessory activity of DC was twice as high as that of the control. This is circumstantial evidence indicating an up-regulation of activity mediated by an increase in intracellular Ca2+ levels and PKC activation.

本实验观察钙载体A_(23187)对小鼠脾脏树突状细胞(dendritic cell.DC)免疫扶佐功能的调节作用。实验结果表明0.5~1μmol/L A_(23187)预处理DC,能使DC在初次混合淋巴细胞反应(1°MLR)和氧化物丝裂原反应中的扶佐作用增强1倍左右,提示DC的免疫扶佐功能与胞浆钙离子水平密切相关。

Recent studies showed that the abnormality of calcium homeostasis inessential hypertension was revealed not only in smooth muscular cellsof blood vessel, but also in other tissues and cells, especially in formedelements of the blood. In this study, some indexes of calcium homeo-stasis in red blood cells of hypertensive persons were observed, andcompared with normal controls. The results were showed as follows:the total calcium concentration in red blood cells of essential hypertensivepatients (EHP) was higher...

Recent studies showed that the abnormality of calcium homeostasis inessential hypertension was revealed not only in smooth muscular cellsof blood vessel, but also in other tissues and cells, especially in formedelements of the blood. In this study, some indexes of calcium homeo-stasis in red blood cells of hypertensive persons were observed, andcompared with normal controls. The results were showed as follows:the total calcium concentration in red blood cells of essential hypertensivepatients (EHP) was higher than that of normal persons, Ca~(2+)-ATPaseactivity of calmodulin-deficient membrane was decreased significantlyin EHP, and the concentration of CaM in cytoplasma was decreasedsignificantly in EHP. The results suggested that the decreased Ca~(2+)-ATPase activity lead to higher level of cytoplasmic free Ca~(2+) andtherefore increased peripheral vascular resistance, while CaM mayinfluence blood pressure indirectly by regulating the activity of Ca~(2+)-ATPase.

原发性高血压钙恒稳异常不仅表现在血管平滑肌,也见于其它组织细胞,尤其是血液的有形成分。本文观察了原发性高血压患者红细胞的某些钙恒稳指标,并与正常人进行了比较。结果表明:高血压患者红细胞总钙浓度较正常人明显增加,红细胞膜Ca~(2+)-ATP酶活性明显降低,胞浆钙调素含量显著降低。结果提示:高血压患者红细胞Ca~(2+)-ATP酶活性下降导致胞内Ca~(2+)浓度升高,从而增加外周血管阻力,而CaM可能是通过调节Ca~(2+)-ATP酶活性间接影响血压的。

On the isolated perfused heart model of septic rats, the present study showedthat: (1) Calcium content and ~(45)Ca--influx of myocardium increased 190%, 208%(P<0.01) and that of mitochondria elevated 332%, 178%; (P<0.01) respectivelywith no change of myocardial ~(45)Ca--release during sepsis. (2) 10~(-8) mol/L calcitoningene--related peptide (CGRP) or 10~(-7) mol/L atriopeptin (ANP) added into the Krebs-Henseleit solution could effectively reduce ~(45)Ca--influx to myocardium and mitocuondri-a with no effect...

On the isolated perfused heart model of septic rats, the present study showedthat: (1) Calcium content and ~(45)Ca--influx of myocardium increased 190%, 208%(P<0.01) and that of mitochondria elevated 332%, 178%; (P<0.01) respectivelywith no change of myocardial ~(45)Ca--release during sepsis. (2) 10~(-8) mol/L calcitoningene--related peptide (CGRP) or 10~(-7) mol/L atriopeptin (ANP) added into the Krebs-Henseleit solution could effectively reduce ~(45)Ca--influx to myocardium and mitocuondri-a with no effect on myocardial ~(45)Ca--release. (3) The calcium uptake reserve of mito-chondria evaluated in ritro showed that the maximal calcium uptake and uptake veloci-ty of mitochondria during sepsis were reduced 34.6%, 33.3% (P<0.01) respective-ly. The data suggested that the net increase of myocardial Ca~(2+) content resulted fromincrease of ~(45)Ca-influx with no change of ~(45)Ca--efflux and the reduction of mitochon-drial Ca~(2+) buffering capacity during sepeis were key events in the pathogenesis of intra-cellular Ca~(2+)-overload. CGRP and ANP could effectively all ievate Ca~(2+)-overload ofmyocardium and mitochondria. This may have some cellular protection action duringsepsis.

本实验在离体灌流败血症休克大鼠心脏模型上,观察到晚期败血症休克时,心肌和心肌线粒体钙含量分别增加190和332(P0.01),~LCa摄入量增加208和178。(P0.01),心肌钙释放量无明显变化 用10mol/L降钙素基因相关肽(CGRP)或10mol/L心房钠尿肽(ANP)灌流离体心脏明显减轻休克时心肌和心肌线粒体的钙超负荷,体外实验观察线粒体摄钙储备的能力,休克时心肌线粒体最大摄钙量减少31.6,摄钙速率降低33%,(P0.01)结论认为,晚期败血症休克,心肌净钙流入量显著增加和线粒体钙转运能力降低导致其对胞浆钙缓冲能力减弱是心肌细胞钙超负荷发生的重要环节CGRP,ANP可显著减轻休克时心肌和线粒体钙超负荷,在休克过程中可能对细胞有保护意义。

 
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