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ig作用
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  “ig作用”译为未确定词的双语例句
     Methods The methods of ELISA and RT-PCR were used to determine the expressions of IL-13 in T cell from periferal blood of asthma patients before and after CTLA4-Ig treatment.
     方法 :用 EL ISA和逆转录 PCR方法测定支气管哮喘患者外周血在 CTL A4 - Ig作用前后 T细胞表达 IL- 13的情况。
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     However, hepatoma chromosomal histone, normal rat liver chromosomal histone or nonhistone all gave negative reactions.
     而正常肝非组蛋白、组蛋白及肝癌组蛋白与抗肝癌染色质Ig作用,均起阴性反应。
短句来源
     Secondary MLR experiment showed cells primed in the presence of CTLA4Ig had a specific hyporesponsiveness when challenged with PBMC from the original donor, yet responded normally to PBMC from the third party donor.
     在再次混合淋巴细胞反应实验中CT LA4Ig作用后的T淋巴细胞对同一供者的外周血单核细胞的刺激表现出特异性无反应 ,而对无关供者的外周血单核细胞的刺激能产生正常的应答反应。
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  相似匹配句对
     Affect of Role Intrusion Detection System
     入侵检测系统的作用
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     The Function of Capital
     资本金的作用
短句来源
     Advances in experimental study of CTLA-4Ig therapy
     CTLA-4Ig治疗作用的实验研究进展
短句来源
     EFFECT OF MITOGEN ON boPBMC PROLIFERATION AND IG-PRODUCTION IN VITRO
     有丝分裂原对离体boPBMC增殖和分泌Ig作用
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  ig treatment
IV Ig treatment led to clinical improvement in all but one patient, who showed an allergic response when exposed to IVIg.
      
IG) treatment (unmodified polyvalent IgG pH 4.25, n=123; forPseudomonas sepsis, n=50, Pseudomonas IgG) on multiple organ failure (MOF) were investigated by means of APACHE II score changes (pretreatment: 23.7±0.6).
      
B cells were studied on rosetted mononuclear cells with either mouse erythrocytes or with Staphylococcus Aureus (Cowan I) bacteria, after a preceeding polyvalent anti-human Ig treatment of the cells.
      
In this study we investigated the long term results of intraperitoneal immunoglobulin (Ig) treatment in continuous ambulatory peritoneal dialyses (CAPD) patients with refractory or relapsing peritonitis.
      
Intraperitoneal Ig treatment was found to be successful in treating peritonitis in all but one patient.
      
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Nuclear immunofluoresoent and immuno-peroxidase labeling, counter-current immunoeleotrophoresis, immunoelectrophoresis, double immunodiffusion and immuno-rocket electrophoresis were used to detect the existence of immuno-specific chromosomal nonhistone proteins in bhe rat hepatoma cells. The anti-hepatoma chromatin Ig absorbed preliminarily by the normal rat nuclei gave positive reactions with hepatoma nuclei and ohromatin extract in all above tests, but ib gave negative reactions with those of the normal rat...

Nuclear immunofluoresoent and immuno-peroxidase labeling, counter-current immunoeleotrophoresis, immunoelectrophoresis, double immunodiffusion and immuno-rocket electrophoresis were used to detect the existence of immuno-specific chromosomal nonhistone proteins in bhe rat hepatoma cells. The anti-hepatoma chromatin Ig absorbed preliminarily by the normal rat nuclei gave positive reactions with hepatoma nuclei and ohromatin extract in all above tests, but ib gave negative reactions with those of the normal rat liver. It might be considered that there were some immuno-specifio chromosomal proteins existing in the hepatoma nuclei. Furthermore, using ultracentrifugally separate hepatoma chromosomal nonhistone proteins to perform the identification, the positive results were obtained. However, hepatoma chromosomal histone, normal rat liver chromosomal histone or nonhistone all gave negative reactions. Besides, there were two sharp precipitated lines between the whole hepatoma ohromatin extract and anti-hepatoma chromatin Ig, while there was only one single precipitated line given by soluble hepatoma chromosomal nonhistone.Experimental results indicate that rat hepatoma chromatin possesses immuno-speoifioity mostly due to its nonhistone components.

用细胞核免疫荧光、免疫过氧化物酶标、对流免疫电泳、免疫电泳、双向免疫扩散及火箭免疫电泳六种免疫鉴定法对肝癌染色质的免疫特性进行鉴定。经正常肝细胞核反复吸收过的抗肝癌染色质Ig能与肝癌染色质起阳性反应,而与正常肝染色质不起免疫反应。 超离心分离的肝癌染色质非组蛋白仍能与抗肝癌染色质Ig作用,起阳性反应;而正常肝非组蛋白、组蛋白及肝癌组蛋白与抗肝癌染色质Ig作用,均起阴性反应。同时见到在抗肝癌染色质Ig与全染色质抽取液间出现二条沉淀线,而与肝癌染色质非组蛋白作用,只有一条沉淀线。实验结果证明,三甲基奶油黄(3′-MeDAB)诱发的大鼠肝癌细胞,具有免疫特异性的染色质,这种特异性是由其染色质非组蛋白引起的。

Objective To investigate the effects of different drugs on primary Sjogren's syndrome(pss) accompanied by hyperimmunoglobulinemia. Methods 42 patients were randomly divided into two groups∶A and B.A group was treated with thymic peptide, while B group was treated with combination of thymic peptide choloroquine, both for 5 months.Results The level of Ig significantly decreased in both groups, especially to IgG(P<0.05),but IgM had no significant change. The efficacy in B group was found to be superior to...

Objective To investigate the effects of different drugs on primary Sjogren's syndrome(pss) accompanied by hyperimmunoglobulinemia. Methods 42 patients were randomly divided into two groups∶A and B.A group was treated with thymic peptide, while B group was treated with combination of thymic peptide choloroquine, both for 5 months.Results The level of Ig significantly decreased in both groups, especially to IgG(P<0.05),but IgM had no significant change. The efficacy in B group was found to be superior to A group.The changes were not noticed until two months after treatment.Conclusion Both thymic peptide and choloroquine can treat pss with hyperimmunoglobulinemia, especially decrease level of IgG. They have synergetic effect. [

目的 探讨原发性干燥综合征 (PSS)伴高球蛋白血症 (Ig)用不同药物治疗的效果。方法 将 42例伴有高球蛋白血症的 PSS的患者随机分为 A组和 B组 ,A组用胸腺肽治疗 ,B组用胸腺肽 +氯喹治疗 ,疗程 5个月。结果 两组患者 Ig均有下降 ,尤其对 Ig G下降更明显 (P <0 .0 5 ) ,B组疗效优于 A组 ,起效时间为 2个月 ,而对 Ig M影响不大。结论 胸腺肽和氯喹均有降低 PSS高Ig作用 ,对 Ig G作用更明显 ,两药合用有协同作用。

AIM To study the effect of rhCTLAIg on human T lymphocytes. METHODS Primary mixed lymphocyte reaction (MLR), secondary MLR and cytotoxicity assay were used. RESULTS CTLA4Ig significantly inhibited primary MLR( P< 0 05) and the maximal inhibition was achieved at 72 h of incubation with CTLA4Ig. Secondary MLR experiment showed cells primed in the presence of CTLA4Ig had a specific hyporesponsiveness when challenged with PBMC from the original donor, yet responded normally to PBMC from the third party donor....

AIM To study the effect of rhCTLAIg on human T lymphocytes. METHODS Primary mixed lymphocyte reaction (MLR), secondary MLR and cytotoxicity assay were used. RESULTS CTLA4Ig significantly inhibited primary MLR( P< 0 05) and the maximal inhibition was achieved at 72 h of incubation with CTLA4Ig. Secondary MLR experiment showed cells primed in the presence of CTLA4Ig had a specific hyporesponsiveness when challenged with PBMC from the original donor, yet responded normally to PBMC from the third party donor. CONCLUSIONS CTLA4Ig can inhibit T cell proliferation and induce T cell anergy in vitro by blocking B7/CD28 co stimulatory pathway.

目的 研究重组人CTIA4Ig对人T淋巴细胞功能的影响。方法 采用初次混合淋巴细胞培养、再次混合淋巴细胞培养及细胞毒实验的方法。结果 CTLA4Ig在浓度高于3mg·L-1时能有效地抑制初次混合淋巴细胞反应 (P <0 0 5 ) ,其在作用 2 4h内不能发挥有效的抑制作用 ,72h能达最大抑制效率 ;在再次混合淋巴细胞反应实验中CT LA4Ig作用后的T淋巴细胞对同一供者的外周血单核细胞的刺激表现出特异性无反应 ,而对无关供者的外周血单核细胞的刺激能产生正常的应答反应。结论 CTLA4Ig在体外能抑制T细胞的增殖 ,并且能诱导T细胞产生抗原特异性无反应

 
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