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组织vegf
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  tissue vegf
     Clinical Significance of Serum IGF-1 Level and Tissue VEGF Expression in Colon Cancer Patients
     结肠癌患者血清IGF-1水平及癌组织VEGF表达的临床意义
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     ④Serum VEGF and tissue VEGF were closely correlative.
     ④血清与组织VEGF之间密切相关(P=0.000)。
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     Expressions of tissue VEGF and b-FGF were significantly decreased after therapy (P < 0.01): Expression of PCNA in tumor were significantly decreased after therapy (P < 0.05).
     组织VEGF和b-FGF表达降低(P<0.01); 肿瘤组织PCNA表达明显下降(P<0.05)。
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     Conclusion NE can induce brain tissue VEGF expression in severe burn rats, which may be an important factor for postburn stress response inducing brain edema.
     结论NE能够诱导严重烧伤大鼠脑组织VEGF表达,可能是烧伤后促进脑水肿形成的一个重要因素。
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     ②Since the level of VEGF between serum and tissue was parallel, so serum VEGF measurement may be the substitution of tissue VEGF.
     ②结直肠癌患者组织与血清VEGF水平密切相关,血清VEGF可替代组织VEGF的检测。
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  “组织vegf”译为未确定词的双语例句
     45.0% positive expression of VEGF and 75.0% nm23-H1 in paracancerous tissues.
     癌旁组织VEGF阳性表达率为45.0%,nm23-H1阳性表达率为75.0%;
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     Expression of VEGF, TGF-β1, MMP-2 and MMP-9 in Krukenberg tumor
     库肯勃瘤组织VEGF,TGF-β_1,MMP-2,MMP-9表达的意义
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     Results(1) There was significant difference between HCC and CCC in VEGF positive expression and MVD(χ~2=5.50,t=2.03,P<0.05);
     结果(1)HCC和CCC肿瘤组织VEGF阳性表达率及MVD方面的差异均具有显著性(2χ=5.50,t=2.03,P<0.05);
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     Rusults:The positive rate of VEGF-C was 69.1%(38/55) and the positive rate of VEGFR-3 was 61.8%(34/55).
     结果:55例宫颈癌组织VEGF-C阳性率为69.1%(38/55),VEGFR-3阳性率为61.8%(34/55),二者表达高度一致(P<0.01)。
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     Relationship between expression of VEGF, Flt1, bFGF and P~(53)and outcome in patients with gastric carcinoma
     胃癌组织VEGF,Flt1,bFGF,P~(53)表达与胃癌预后的关系
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     Organization
     组织
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     The expression of VEGF in pterygium
     VEGF在翼状胬肉组织中的表达
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     Expression of VEGF and PTEN in nephroblastoma
     肾母细胞瘤组织VEGF和PTEN的表达
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     The family of VEGF also include VEGF-B, VEGF-C and VEGF-D.
     刀、VEGF
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     Primary rat skeletal myoblasts were infected with both the hVEGF_ 165 recombinant adenovirus and Tet-off regulatory virus.
     VEGF165。
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  tissue vegf
In contrast to increased tissue VEGF expression, the arterial and femoral venous plasma levels of VEGF were decreased by training, which may indicate an exercise-induced enhancement of the peripheral uptake of VEGF.
      
These findings also raise the possibility that estrogen effects on uterine edema, proliferation and tumoral transformation may involve local increases in tissue VEGF production.
      
We conclude that serum VEGF could be a useful marker for monitoring head and neck carcinoma patients, but that serum and tissue VEGF levels do not appear to correlate with each other.
      
Also, exercise training increased capillary density, decreased tissue endostatin and increased tissue VEGF in the skeletal muscle (AT).
      
To determine tissue VEGF levels, tumors were excised from the dorsal skinfold chambers and frozen in liquid nitrogen.
      


Objective To investigate the relationship of vascular endothelial growth factor (VEGF) and angiogenesis to the progression of gastric carcinoma (GC). Methods VEGF protein expression and microvessel density (MVD) in 56 cases of human GC and VEGF mRNA expression in some cases were examined by use of immunohistochemical staining and in situ hybridization technique respectively. MVD and VEGF expression were analysed together with their relation to histologic types, depth of invasion, growth pattern, lymph node...

Objective To investigate the relationship of vascular endothelial growth factor (VEGF) and angiogenesis to the progression of gastric carcinoma (GC). Methods VEGF protein expression and microvessel density (MVD) in 56 cases of human GC and VEGF mRNA expression in some cases were examined by use of immunohistochemical staining and in situ hybridization technique respectively. MVD and VEGF expression were analysed together with their relation to histologic types, depth of invasion, growth pattern, lymph node metastasis, distant metastasis and relapsing rate of GC. Results MVD was significantly higher in VEGFpositive GC than in VEGFnegative GC (P<001). MVD and VEGF positively correlated with depth of invasion (P<0.01), lymph node metastasis (P<0.05) and distant metastasis (P<0.05), but their relation to the histologic types and growth pattern of GC was not significant. The 5 year survival rate was significantly lower in GC patients with positive expression of VEGF or with MVD≥43. The expression of VEGF mRNA was consistent with that of VEGF protein, but the distribution is different. Conclusion VEGF is highly related to angiogenesis of GC and promotes growth, invasion and metastasis of GC. VEGF expression or MVD is one of the predictors for the biological behavior of GC.

目的探讨血管内皮细胞生长因子(VEGF)和血管生成与胃癌发展的关系。方法应用免疫组织化学和原位分子杂交技术,检测56例人胃癌组织VEGF蛋白表达和微血管密度(MVD)及部分胃癌VEGFmRNA表达,分析VEGF和MVD、及其与胃癌组织学分型、浸润深度、生长方式、淋巴结转移、远处转移和预后的关系。结果VEGF阳性者MVD值显著高于阴性者(P<001),VEGF表达和MVD与胃癌浸润深度(P<001)、淋巴结转移(P<005)和远处转移(P<0.05)密切相关,而与组织学分型和生长方式无关(P>005);VEGF表达阳性或MVD≥43的胃癌患者5年生存率较低;VEGFmRNA表达与VEGF蛋白表达具有一致性,但其分布不同。结论VEGF与胃癌的血管生成密切相关,对胃癌的生长和浸润转移有促进作用,VEGF和MVD可作为反映胃癌生物学行为的指标之一

PURPOSE To explore the expression of VEGF in invasive breast cancer and its correlations with angiogenesis. metastasis and other clinicopathological variables. METHODS VEGF was stained immunohistochemically in101 invasive breast cancer. RESULTS No immunostaining of VEGF was observed in normal breast tissues and benign lesions. Good correlations of VEGF expression were noted with histological grades (P<0' 05). lymph nodestatus (P<0. 005), distant metastasis (PRO. 005). early death (within two years) (PRO. 005)....

PURPOSE To explore the expression of VEGF in invasive breast cancer and its correlations with angiogenesis. metastasis and other clinicopathological variables. METHODS VEGF was stained immunohistochemically in101 invasive breast cancer. RESULTS No immunostaining of VEGF was observed in normal breast tissues and benign lesions. Good correlations of VEGF expression were noted with histological grades (P<0' 05). lymph nodestatus (P<0. 005), distant metastasis (PRO. 005). early death (within two years) (PRO. 005). and with MVD (P<0. 05), but not with age, tumor size (P>0. 05) in invasive breast cancer. CONCLUSION VEGF is an importantangiogenic factor. Breast cancer patients with VEGF-positive staining may be at high risk for development ofmetastasis and may have un favorable prognosis.

目的探讨血管内皮生长因子(VEGF)在乳腺癌中的表达及其与血管生成,肿瘤转移等参数之间的关系。方法对101例浸润性乳腺癌组织的VEGF表达进行了免疫组化检测。结果正常乳腺组织及良性病变组织均无VEGF表达。乳腺癌VEGF表达与组织分化(P<0.05),淋巴结转移(P<0.005),远处转移(P<0.005)及早期死亡(P<0.005)密切相关,与乳腺癌组织微血管密度(MVD)亦呈显著相关性(P<0.05);与患者年龄,肿瘤大小无关(P>0.05)。结论VEGF是促进乳腺癌血管生成的主要因素。VEGF阳性的乳腺癌组织分化差,易发生转移,预后不良。

Objective: To study the relationship of VEGF, DNA and AgNOR in human thy-roid carcinoma and the metastasis of lymphaden. Methods: The expression of VEGF, DNA and Ag-NOR were stuided by immunohistochemistry and image analysis system. Results: On the contrary,the expression of VEGF was negative in 10 case of thyroid tissue. The positivity rates of VEGF were72. 79 %, 97 % in 136 case of thyroid carcinoma and in the metastasis of lymphaden respectively. Theaverage value of DNA and AgNOR number in more than 5 years...

Objective: To study the relationship of VEGF, DNA and AgNOR in human thy-roid carcinoma and the metastasis of lymphaden. Methods: The expression of VEGF, DNA and Ag-NOR were stuided by immunohistochemistry and image analysis system. Results: On the contrary,the expression of VEGF was negative in 10 case of thyroid tissue. The positivity rates of VEGF were72. 79 %, 97 % in 136 case of thyroid carcinoma and in the metastasis of lymphaden respectively. Theaverage value of DNA and AgNOR number in more than 5 years Survival groups was lower than inless than 5 years death groups (P < 0. o1, P < 0. 05 ). Conclusion: Examining the expression ofVEGF, DNA and AgNOR may be avilable to estimate the patients prognosis.

目的研究血管内皮生长因子(VEGF)在甲状腺癌及其转移淋巴结中的表达及与癌细胞DNA倍体、核仁形成区(AgNOR)的关系。方法应用免疫组织化学SABC法检测136例甲状腺癌及淋巴结中VEGF的表达,同时进行细胞DNA含量及AgNOR自动图像分析检测,10例正常甲状腺组织作对照。结果10例正常甲状腺组织VEGF(一),136例甲状腺癌组织中VEGF阳性表达72.79%(99/136),淋巴结中VEGF阳性表达97%(132/136)。DNA倍体平均值及AgNOR计数5年以上生存组病例明显低于5年以内死亡组(P<O.01,P<O.05)。结论检测VEGF、DNA倍体及Ag-NOR有助于评估甲状腺癌的生物学行为及预后。

 
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