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粘附移行
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  adhesion and migration
     Effects of tumor necrosis factor α on adhesion and migration of lens epithelial cells
     肿瘤坏死因子对晶状体上皮细胞的粘附移行作用
短句来源
     Effects of disintegrin on adhesion and migration of human lens epithelial cells
     去整合素对人眼晶状体上皮细胞的粘附移行作用
短句来源
  “粘附移行”译为未确定词的双语例句
     The changes in adhesion and transmigration of cells are important in the formation, infiltration and spreading of tumor.
     细胞粘附移行的变化在肿瘤的形成、浸润和播散中起重要作用。 肿瘤细胞之间、肿瘤细胞与细胞外基质(ECM),肿瘤细胞与内皮细胞的粘附是由不同的粘附分子来介导的。
短句来源
     During the process of tumour growth , tumour cells secret lots of VEGF, and then VEGF combines with its receptor on near host vessel and induces the endothelial cells to compound many proteolysis, which can destroy the basal membrane of host vessel and abate its protective function.
     此外,VEGF增加血管通透性,促进血浆成分包括大量的纤维蛋白原渗出,形成内皮细胞粘附移行所必需的新基质。 同时,内皮细胞在VEGF的刺激下增殖移行,穿破母血管基底膜沿新的细胞外基质向刺激源移行,延伸进肿瘤组织,交叉吻合形成肿瘤的供血血管网。
短句来源
     Objective To explore the effects of Zhaoke defibrase and anti-α vβ 3 mAb (23C6) on the adhesion and immigration of bovine retinal vascular endothelial cells.
     目的 探讨蛇毒制剂兆科降纤酶和抗αvβ3整合素抗体 2 3C6对血管内皮细胞粘附移行的影响。
短句来源
  相似匹配句对
     Effects of tumor necrosis factor α on adhesion and migration of lens epithelial cells
     肿瘤坏死因子对晶状体上皮细胞的粘附移行作用
短句来源
     Effects of Laminin and Fibronectin on Biological Behavior of RLECs
     层粘蛋白、纤维连接蛋白对兔晶体上皮细胞粘附移行的影响
短句来源
     Neural cell adhesion molecule
     神经细胞粘附分子
短句来源
     Advance of the Studies on the Adhesion Molecules of Blood Cells
     血细胞的粘附分子
短句来源
     Improvement of Strategy for Data Migration
     数据移行策略改进
短句来源
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  adhesion and migration
The urokinase type plasminogen activator (urokinase) plays a pivotal role in the regulation of cell adhesion and migration during tissue remodeling.
      
Protease cascades such as the plasminogen activation system exhibit a dual role in cell invasion by promoting pericellular proteolysis as well as by regulating cell adhesion and migration in a non-proteolytic fashion.
      
Cell adhesion and migration of cells within collagen-based biomaterials may be controlled by modifying the adhesive properties of collagen.
      
Effect of Malytea Scurfpea fruit on adhesion and migration of melanocyte
      
Accumulating evidence suggests that protease receptors and their cognate protease ligands play important roles in cell-signaling events that regulate cell adhesion and migration in inflammation as well as tumor invasion and metastasis.
      
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Objective:The pathogenesis of posterior capsule opacification has correlation with migration, proliferation and differentiation of residual lens epithelial cells (LECs) after cataract surgery The aim of this study was to explore the effects of tumor necrosis factor α (TNF α) on LECs' adhesion and migration on extracellular matrix, and the expression of integrins during the course Methods:The cell adhesion and migration assays were used to assess the effects of TNF α on LECs' adhesion and migration on extracellular...

Objective:The pathogenesis of posterior capsule opacification has correlation with migration, proliferation and differentiation of residual lens epithelial cells (LECs) after cataract surgery The aim of this study was to explore the effects of tumor necrosis factor α (TNF α) on LECs' adhesion and migration on extracellular matrix, and the expression of integrins during the course Methods:The cell adhesion and migration assays were used to assess the effects of TNF α on LECs' adhesion and migration on extracellular matrix, and the influence of LECs' incubation with five different monoclonal antibodies specific for integrin alpha subunits 2, 3, 5 and beta subunits 1, 2 The regulation of integrins expression by TNF α was studied by fluorescence activated cell sorting (FACS) technique using indirect immunofluorescent staining Results:TNF α could significantly promote LECs' adhesion and migration on type Ⅳ collagen, laminin and fibronectin The most effective concentration of TNF α was 10 U/ml According to the results of antibody blocking, β1, α2, α3, α5 subunits have involved in cell adhesion and α subunits play a role in cell migration The integrins expression on LECs was obviously up regulated by TNF α Conclusion: As collagen, laminin, fibronectin are the main components of lens capsule, TNF α could enhance the interactions between lens epithelial cells and lens capsule This is achieved partly through the up regulation of integrins expression on lens epithelial cells by TNF α

目的 :探讨肿瘤坏死因子α (tumornecrosisfactorα ,TNF α)对晶状体上皮细胞在细胞外基质上的粘附移行作用 ,以及在此过程中整合素分子的表达情况。方法 :借助细胞粘附实验和移行实验研究TNF α对体外培养的牛晶状体上皮细胞在细胞外基质上的粘附和移行 ,以及整合素抗体封闭后对细胞的影响。TNF α对细胞表面整合素的表达调节经免疫荧光染色后由流式细胞仪检测。结果 :TNF α可以明显促进晶状体上皮细胞在Ⅳ型胶原、层粘蛋白、纤维连接蛋白上的粘附移行。抗体封闭实验表明整合素 β1、α2、α3、α5亚基参与细胞的粘附 ,在细胞移行中发挥主要作用的是α亚基而非 β亚基。流式细胞仪检测表明TNF α可上调晶状体上皮细胞中整合素的表达。结论 :胶原、层粘蛋白、纤维连接蛋白是晶状体囊的主要成分 ,肿瘤坏死因子α促进晶状体上皮细胞与晶状体囊膜成分的粘附移行 ,该作用的发挥至少部分通过TNF α上调整合素分子在细胞上的表达而实现

Transforming growth factor (TGF β)regulatesabroadrange of biologicalprocesses ,including cellgrowth ,development ,differentiation ,andapoptosis .TGF βplaysacentralroleintheprocessofwound healing ,suchaschemotaxis ,changingtherateofre epithelialization ,reductionoffibrosis ,andscarhealing . [

转化生长因子 β是一类分泌型多肽信号分子 ,有调节细胞的增殖、分化、粘附、移行及凋亡的作用。在创伤愈合过程中 ,转化生长因子 β具有趋化作用 ,可促进瘢痕形成 ,改变伤口愈合进度 ,并控制纤维化

Objective To study the effects of laminin(LN) and fibronectin (FN) on adhesion and migration of lens epithelial cells (LECs) in vitro.Methods RLECs were cultured in vitro. The changes in adhesion and migration under the action of LN and FN molecule and the variation in morphology and cytoskeleton were observed.Results Along with the increase of the concentration of LN and FN,the ability of adhesion and migration of RLECs on the corresponding matrix increased gradually,especially within the extent of the lower...

Objective To study the effects of laminin(LN) and fibronectin (FN) on adhesion and migration of lens epithelial cells (LECs) in vitro.Methods RLECs were cultured in vitro. The changes in adhesion and migration under the action of LN and FN molecule and the variation in morphology and cytoskeleton were observed.Results Along with the increase of the concentration of LN and FN,the ability of adhesion and migration of RLECs on the corresponding matrix increased gradually,especially within the extent of the lower concentrations.Administration of specific antibodies against LN and FN showed that the effects of ECM components on RLECs were inhibited and had matrix specificity.The cytoskeleton network was reorganized and its morphological changes were positively correlated with the function of adhesion and migration.Conclusion ECM component LN and FN might markedly affect adhesion and migration of RLECs and might play a critical role in the development of posterior capsule opacification.

目的 探讨层粘蛋白 (laninin ,LN)、纤维连接蛋白 (fibronectin ,FN)对兔晶体上皮细胞 (RLECs)粘附性和移行性的影响。方法 观察外源性FN、LN对兔晶体上皮细胞粘附、移行及其细胞骨架的影响。结果 随着FN、LN浓度升高 ,RLECs在相应的细胞外基质上粘附和移行能力增强 ,低浓度时增加幅度较大 ;加入相应抗FN、LN抗体 ,RLECs在相应基质上的移行产生不同程度的抑制作用 ,细胞骨架也不能充分铺展 ,并且这一变化与细胞粘附性和移行性呈正相关。结论 FN、LN可诱导RLECs移行、粘附 ,因而可能在后囊膜混浊的形成中起重要的作用

 
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