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临床     
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  clinical
    Effect of homoharringtonine on apoptosis in leukemic cells,related mechanism and clinical significance
    高三尖杉酯碱诱导原代白血病细胞凋亡、相关机理及临床意义
短句来源
    A Clinical Review of Lymphatic Metastasis of Oral SCC and a Study of Cancer's Impacts on Lymphangiogenesis
    口腔癌淋巴转移规律临床回顾及肿瘤对淋巴管生成作用研究
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    CLINICAL STUDY ON LOCAL IMMUNE RESPONSE TO ULTRASONICALLY GUIDED SUPERANTIGEN INJECTION WITH MICROWAVE COAGULATION THERAPY FOR LIVER CANCER AND ITS RELATION WITH PROGNOSIS
    超声引导超抗原瘤区注射协同微波治疗肝癌后局部免疫应答与预后关系的临床研究
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    Value of ~(18)FDG-PET in the diagnosis of lung cancer and expression and clinical significance of glucose transporter 1 in lung cancer
    18FDG-PET在肺癌诊断中的价值和GLUT1在肺癌细胞中的表达及其临床意义的相关研究
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    The Experimental Studies and Clinical Application of Transplantation of Microencapsulated Bovine Chromaffin Cell for Pain Treatment
    微囊嗜铬细胞移植治疗疼痛的实验研究和临床应用
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  clinic
    The clinic and experiment research on related factor of bone metastasis of bresat cancer
    乳腺癌骨转移相关因素的实验与临床研究
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    Clinic Application of Neoadjuvant Intraarterial Chemotherapy for Breast Cancer
    乳腺癌新辅助动脉灌注化疗的临床应用
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    Integrin Expression and Its Clinic Values in Urologic Tumors
    整合素在泌尿系肿瘤中的表达及其临床意义的初步研究
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    Clinic and Experimental Study of MDR of Liver Cancer and Transcatheter Arterial Embolization/Infusion
    肝癌多药耐药与介入治疗临床和实验研究
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    Clinic Investigations of the Unconventional Operations for the Advanced Lung Cancer
    中晚期支气管肺癌非常规手术切除的临床研究
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  clinical practice
    Study on Animal Experiment and Clinical Practice for Interdicting and Reversing Treatment of Esophageal Squamous Epithelium Precancerous Lesion
    食管癌前病变逆转和阻断治疗的动物实验及临床研究
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    Clinical Practice in Primary Hyperparathyroidism
    原发性甲状旁腺机能亢进症的临床实践
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    Establisbed oneself the detection of serum prostate spe-cific antigen and application in clinical practice
    自建血清前列腺特异抗原测定方法的临床应用
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    COX-2 inhibitor has the function of prevention and suppression of lung cancer in clinical practice.
    COX-2抑制剂的临床应用有预防和抑制肺癌的作用。
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    [Objective]To compare the results of clinical application of liquid and solid protein chip technology in detecting multiple tumor markers,and discuss the feasibility of liquid protein chip in clinical practice.
    [目的]比较液相与固相蛋白芯片检测多肿瘤标记物的临床应用效果,并探讨液相蛋白芯片应用于临床检验的可行性。
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  clinical expressions
    Objective To explore the correlation between the concentrations of LEP,IGF-1, TNF-α,E 2, T and PRL and such clinical expressions of female mammary cancer as clinical stages, pathological types, conditions of lumph node in axillary fossa.
    目的  探讨血清瘦素 (LEP)、胰岛素样生长因子 1(IGF 1)、肿瘤坏死因子 α(TNF α)、雌二醇 (E2 )、睾酮 (T)及垂体泌乳素 (PRL)与女性乳腺癌患者临床分期、病理类型、腋窝淋巴结状态等之间的相互关系。
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    In this paper we analyse the histopathological characteristics, clinical expressions and treatment effect of 18 cases of melanoma of nasal cavity.
    分析18例鼻腔原发性恶性黑色素瘤的病理特点,临床表现及其治疗效果。
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      clinical
    Guanidine-type compounds that reached clinical status include amongst others the potassium channel opener, pinacidil and the histamine H2-receptor antagonists (e.g.
          
    (ii) Other compounds have proceeded through preclinical and/or clinical development: CXCR4 antagonists (i.e.
          
    (iii) Yet other compounds, acting by novel mechanisms, have recently been identified as anti-HIV agents that seem worthy of further (pre)clinical development: cell receptor CD4 downmodulators (i.e.
          
    PRE-CLINICAL AND CLINICAL PHARMACOKINETICS OF THE DIASTEREOMERS OF ARTEETHER, A POTENT ANTIMALARIAL
          
    Pre-clinical studies were carried out (N=3) by oral, intramuscular and intravenous routes, while clinical studies (N=13) were performed intramuscularly.
          
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      clinic
    The applicability and efficiency of the electroencephalogram (EEG)-based method of biofeedback (BFB) training in correcting functional disorders in pregnancy have been evaluated in an obstetric/gynecological clinic in 65 pregnant women.
          
    An epithermal neutron source based on a compact tandem accelerator is being built at the Budker Institute of Nuclear Physics for use in neutron capture therapy at a cancer clinic.
          
    The data obtained shed light on some specific features in the composition of clayey rocks, which can be used for mud cure of arthritis and rheumatism in the Health and Rehabilitation Clinic of the Nature Health Association of Iceland, Hveragerei.
          
    Mono- clinic system, space group C2/c, a = 13.4877(10), b = 9.5843(7), c = 7.9564(6) ?, β = 116.124(2)°, V = 923.45(12) ?3.
          
    The crystals are mono-clinic: a= 14.678(3) ?, b= 11.866(2) ?, c= 19.655(4) ?, β = 102.17(3)°, V= 3346(1) ?3, Z= 4, ρcalcd= 1.364 g/cm3, space group C2/c.
          
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      clinical practice
    Multiple-drug therapy is common in current clinical practice.
          
    Therefore, it is a very important subject in clinical practice to measure and classify the ECG ST segment.
          
    They have become closer to the clinical practice, standardized and observable.
          
    Based on continuously solidifying theories and clinical practice, many advanced concepts with applicable clinical frameworks have been established, thus making splenic surgery an indispensable division in modern surgery.
          
    Based on these properties, we elaborated a new medicinal drug "Actipol" which was introduced in clinical practice.
          
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      clinical expressions
    Adynamia episodica and paramyotonia congenita are occasionally regarded as different clinical expressions of a common underlying disease.
          
    McArdle's disease: two clinical expressions in the same pedigree
          
    Clinical expressions of cognition and behaviour in Alzheimer's disease (AD) patients are heterogeneous.
          
    Conversely, different clinical expressions of the defect of a single enzyme may be attributed to allelic mutations.
          
    Familial CDI is a hereditary form of primary CDI with a variety of clinical expressions among affected individuals which is said to be related to varying degrees of an arginine vasopressin (AVP) deficiency.
          
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    This paper reports the results of the clinical use of Corydalis B as an analgesic in 72 patients with various forms of pain. In 64 cases the drug was used in a single dose, usually of 75 mg. by oral route, while in the other 8 cases repeated doses were given orally over a period of 3 to 21 days. The pain was completely abolished or definitely improved in 50 cases (78.1%) of the former group and in all 8 cases of the latter group. The analgesic effect appeared to be most marked in medical cases with dull pain...

    This paper reports the results of the clinical use of Corydalis B as an analgesic in 72 patients with various forms of pain. In 64 cases the drug was used in a single dose, usually of 75 mg. by oral route, while in the other 8 cases repeated doses were given orally over a period of 3 to 21 days. The pain was completely abolished or definitely improved in 50 cases (78.1%) of the former group and in all 8 cases of the latter group. The analgesic effect appeared to be most marked in medical cases with dull pain in the chest or abdomen, as in cases of peptic ulcer and lobar pneumonia. Drowsiness was found as a side-effect in 28% of the cases after a single dose of the drug and in 6 of the 8 cases treated with repeated doses. In no case was any serious toxic action noted. According to the preliminary Observations herein reported, further clinical trial with the use of Corydalis B as an analgesic agent seems warranted.

    本文报告72例试用延胡索素乙硫酸盐作为鎮痛剂的临床观察,其中64例为单剂用药,主要为一次口服75毫克,另8例为长期口服。单剂用药64例中完全止痛及疼痛减轻者共50例,占78.1%,长期服药8例均有效,鎮痛作用在内科胸腹部鈍痛病例较著。用药后未見重要副作用,单剂用药者28%发生嗜睡。长期用药的8例中6例有嗜睡,血与尿常規、大便次数、血压、心率等均无明显改变。据本文病例的初步临床应用结果,延胡索素乙对钝痛有一定的镇痛效果值,得进一步试用。

    This communication is an analysis of the scanning results of sixty cases of clinically suspected hepatic space-occupying lesions which were subsequently pathologically proved. This series comprises 36 cases of primary carcinoma of the liver, 8 eases of metastatic carcinoma of the liver, 3 eases of schistosomal granuloma of the liver, 2 eases of liver cyst, 2 cases of liver abscess, and 1 case each of secondary mesothe-lioma of liver, cavernous haemangioma of liver,lymphangioma of liver, adenocarcinoma of gall-bladder,...

    This communication is an analysis of the scanning results of sixty cases of clinically suspected hepatic space-occupying lesions which were subsequently pathologically proved. This series comprises 36 cases of primary carcinoma of the liver, 8 eases of metastatic carcinoma of the liver, 3 eases of schistosomal granuloma of the liver, 2 eases of liver cyst, 2 cases of liver abscess, and 1 case each of secondary mesothe-lioma of liver, cavernous haemangioma of liver,lymphangioma of liver, adenocarcinoma of gall-bladder, retroperitoneal undifferentiated carcino-ma, carcinoma of transverse colon, congenital intrahepatic cholangiectasis, carcinoma of panc-reas and cholecystitis. We could observe the configuration, struct-ure, location and size of the liver by this method.Each kind of hepatic space-occupying lesions had its own characteristic appearences in the liver scans.When a positive finding in the liver scan,was obtained, no single case was mistaken; but in case of negative finding in the liver scan, the possibility of space-occupying lesions could not be ruled out. Fifty-nine cases in this series showed typical changes in the liver scans, only one case of primary carcinoma of the liver exhibited no area of decreased activity in the liver scan, thus produeing false-negative result.Radioisotope scanning of the liver is accurate and painless and is considered to be the best method in the diagnosis of hepatic spaceoccupying lesions, particularly in the diagnosis and differ-ential diagnosis of carcinoma of the liver.

    肝脏扫描术对肝脏占位性病变的诊断有很大的价值。我们总结了我院附属中山医院1959年以来300余例肝脏扫描中,经病理证实的60例临床上疑似肝脏占位性病变的扫描结果。本文着重讨论肝癌在扫描图上的表现及其与其他占位性病变的监别诊断,以及本方法和其他诊断方法的对比等。

    Transfer factor (TP) is a dialysable (ultrafilterable) extract of sensitised leukocytes. It transfers cellular immunity from a skin test positive donor to a skin test negative recipient. Currently TF is recognized as one of the most potent immunological reagents. In this paper the detailed method for preparation of transfer factor from normal blood bank donors has been described and some physico-chemical and biological properties of the TF preparations have been examined. The production of TF is briefly as follows:...

    Transfer factor (TP) is a dialysable (ultrafilterable) extract of sensitised leukocytes. It transfers cellular immunity from a skin test positive donor to a skin test negative recipient. Currently TF is recognized as one of the most potent immunological reagents. In this paper the detailed method for preparation of transfer factor from normal blood bank donors has been described and some physico-chemical and biological properties of the TF preparations have been examined. The production of TF is briefly as follows: After separation of the plasma (for plasma products), the buffy coats are harvested and pooled. The contaiminating red blood cells are disrupted by tris buffered or isotonic NH_4Cl solution. The pooled leukocytes having been washed iwice with cold normal saline are then alternately frozen and thawed ten times with dry ice in acetone and a 37℃ water bath. The cell lysate is placed in dialysis tubing and dialysed in the cold for 36~48 hours against running pyrogenfree deionized water. The dialysate is lyophilized. The yellowish white powder is saved and redissolved in the desired volume of pyrogen-free deionized water, and passed through a Seitz filter (EKS). 2ml of the sterile TF solution (equivalent to the dialysate of 4×10~8 leukocytes) are placed in each ampoule. The final product is stored at -20℃.The TF preparation is protein-free as determined by protein precipitating reagents. It contains ca. 148μg of peptides and 14μg of ribose per mg of dry powder. The ultraviolet absorption curve gives a peak at 250~251nm. Adenine, guanine and uracil are present in the paper chromatogram of the TF acid hydrolysate. Silica- gel thin layer chromatography reveals four spots stained with ninhydrin. Sephadex G-25 filtration gives reproducibly a characteristic elution pattern yielding 3 main peaks and several small peaks with many of the eluted peaks beyond the total volume of the column. The results of animal experiments show that the TF preparations are non-toxic, non-anaphylactic and non-antigenic.So far over 160 patients (variously afflicted with herpes zoster, chronic hepatitis B, systemic lupus erythematosus, primary carcinoma of the liver, carcinoma of the lung and leukemia) have been treated with the TF preparations. The results will be published elsewhere.

    转移因子是致敏白细胞中的可透析物质,能将一个有免疫能力的人的某些细胞免疫力转移给无免疫力的人。所以供给转移因子可能是一种有效的免疫治疗措施。本文详细介绍综合利用血源制备正常人转移因子的方法,并分析其某些理化性质和生物学性质。收集分离血浆后的白细胞层,用三羟甲基氨基甲烷缓冲的或等渗的氯化铵溶液破坏其中污染的红细胞,白细胞经生理盐水洗涤后进行10次冻融,白细胞匀浆对流动去离子水透析,透析液冷冻干燥、除菌分装。每安瓿2毫升转移因子注射液相当4×10~8个白细胞的透析物,保存于-20℃备用。本制剂蛋白质定性检查阴性;每毫克干粉约含多肽148微克、核糖14微克;在250~251毫微米有吸收高峰;转移因子酸水解液硷基纸层析有三种硷基;硅胶薄板层析呈四个茚三酮显色点;葡聚糖G-25凝胶过滤呈可重复的特征性洗脱图谱,具有3个主要峰及若干个小峰,主要洗脱部分在V_t之后。动物实验表明此制剂无毒性、无过敏性和抗原性。本制剂已用于临床治疗带状疱疹、系统性红斑狼疮、慢性乙型肝炎、原发性肝癌、肺癌及白血病等一百六十余例,结果将另文发表。

     
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