Method: 86 patients with first-episode schizophrenia were treated with risperidone fo r 6 months and then detected the levels of DA and HVA in CSF with high performan ce liquid chromatography and electrochemical detector(HPLC-ECD),the effects wer e evaluated with PANSS.
Results Of 36 cases first-episode schizophrenia patients who completed the 6 weeks treatment,10 cases(27.8%) were cured,12 cases(33.3%) were markedly improved,8 casrs(22.2%) were improved and 6 cases(16.7%)had no response. Total effective rate was 83.3%,Side effects were slight.
Objectives: To study the effects of Clozapine and Risperidone on serum interleukin-2 (IL-2) of patients with first episode schizophrenia paranoid type, and to explore the relationship between IL-2 and psychopathology.
METHODS:A total of 86 patients with first episode schizophrenia were selected in Zhumadian Municipal Psychiatric Hospital with random sampling method. The patients were randomized into study group and control group.
Method:24 patients of first episode schizophrenia and schizophrenic form psychosis were treated with clozapine for 18 weeks. The insulin sensitivity index (ISI) and weight were measured before treatment and at the end of 18th week after the treatment.
Methods: sixty first-episode schizophrenic patients were randomly divided into two groups, which treated with clozapine andrisperidone respectively. The subjects were given either clozapine(75mg/d) or risperidone(1mg/d) for 3 days. Then gradually added to efficient dosage till day 14, maintained the dosage to 8 weeks.
This study was undertaken with the aim to identify the prevalence and patterns of substance abuse among patients with first-episode schizophrenia in the city-state of Singapore.
Social network among young adults with first-episode schizophrenia spectrum disorders
A descriptive study of pathways to care among hospitalized urban African American first-episode schizophrenia-spectrum patients
In the past year, it has focused on changes in "at-risk" and first-episode schizophrenia populations and has been used by researchers to characterize phenotypes of patients with schizophrenia prior to including them in genetic research.
For the present study, 70 schizophrenic patients (40 with chronic and 30 with first-episode schizophrenia) were compared to 30 healthy controls on a large battery of neuropsychological tests.
Results: Chronic schizophrenic patients had significantly reduced velocity gain, took longer to respond to the change in target direction and made more catch-up saccades than both first-episode schizophrenic patients and controls.
Decreased striatal dopamine transporter binding assessed with [123I] FP-CIT in first-episode schizophrenic patients with and wit
Neuropsychological impairment and psychopathology in first-episode schizophrenic patients related to the early course of illne
Smooth pursuit eye tracking over a structured background in first-episode schizophrenic patients
Smooth pursuit performance was measured in 23 first-episode schizophrenic patients and 23 healthy controls matched for age and estimated IQ, both in the dark and over a structured background (a random checkerboard of black and white squares).