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首发精神分裂症
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  first episode of schizophrenia
    The Contrast Investigation between Quetiapine and Perphenazlne in the Treatment of First Episode of Schizophrenia in Children
    奎硫平与奋乃静治疗儿童首发精神分裂症对照研究
短句来源
    The contrast investigation between risperidone and perphenazine in the treatment of first episode of schizophrenia in children and adolescences
    利培酮与奋乃静治疗儿童少年期首发精神分裂症对照研究
短句来源
    Objective To explore the efficacy, safety and the main side effects in the treatment of first episode of schizophrenia or schizophreniform disorder in children and adolescences.
    目的研究利培酮治疗儿童少年期首发精神分裂症或分裂样精神病的疗效、安全性和不良反应。
短句来源
    Conclusions The efficacy of risperidone in the treatment of first episode of schizophrenia in children and adolescences is a little better than that of perphenazine, and it's safe and the main side effects are small.
    结论利培酮对儿童少年期首发精神分裂症疗效略优于奋乃静,且安全性好,不良反应小。
短句来源
    ObjectiveTo assess the efficacy,safety and dosage of risperidone in the treatment of children with first episode of schizophrenia or schizoid psychosis.
    目的探讨利培酮治疗儿童首发精神分裂症或分裂样精神病的临床疗效、安全性和药物剂量。
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  “首发精神分裂症”译为未确定词的双语例句
    Conclusion: It suggested that risperidone is an effective and safe antipsychotic in the treatment of childhood patients with schizophrenia.
    结论:对儿童期首发精神分裂症,利培酮疗效较好,安全性高。
短句来源
    Conclusions The serum(IL-1β) level is higher in first-episode children with schizophrenia. Obesity is easy to be seen in the patients treated with risperidone. It may be one of reasons to leptin resistence to decrease serum IL-1β levels.
    结论首发精神分裂症患儿血清IL-1β水平明显升高,利司培酮治疗后易出现药源性肥胖,低IL-1β水平可能是瘦素抵抗的原因之一。
短句来源
    ConclusionRisperidone is an effective and safe antipsychotic with high compliance in children with schizophrenia of first attack.
    结论利培酮对于首发精神分裂症或分裂样精神病病儿的治疗安全、可靠,不良反应轻,病儿依从性高。
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  first episode of schizophrenia
The first episode of schizophrenia, usually considered the first five years of the illness brings with it a challenging period of acceptance and adaptation for patients and their families.
      
The treatment descriptions and examples are taken from work with 71 patients in the first episode of schizophrenia, many of whom experienced intense feelings of unworthiness, expressed in their words and behavior as guilt and shame.
      
Four out of five patients who stop taking their medications after a first episode of schizophrenia will have a relapse.
      
Most people make a good recovery from a first episode of schizophrenia, although this can take several months.
      
Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder.
      
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Objective:This study explored the differences of the clinical features and treatments between first-onset and recrudescent schizophrenia in children.Methods:We have reviewed the case recordings both of 28 first-onset schizophrenia in children and 28 recrudescent schizophrenia in children.The clinical features and treatments have been compared.Results:Both groups had two clinical core features,they are ① thought disorder;②behavior disorder.These two groups were mainly treated with atypical antipsychotics.Conclusions:There...

Objective:This study explored the differences of the clinical features and treatments between first-onset and recrudescent schizophrenia in children.Methods:We have reviewed the case recordings both of 28 first-onset schizophrenia in children and 28 recrudescent schizophrenia in children.The clinical features and treatments have been compared.Results:Both groups had two clinical core features,they are ① thought disorder;②behavior disorder.These two groups were mainly treated with atypical antipsychotics.Conclusions:There was no significant difference of clinical features between the first-onset schizophrenia in children and the recrudescent schizophrenia in children.It is important that the first-onset schizophrenia in children should be diagnosed accurately and then be treated immediately and correctly.

目的 :探讨儿童首发与复发精神分裂症的临床特点及治疗选择。方法 :在一般项目、核心症状、家族史、脑电图、电疗、药物治疗、疗效及电疗副作用等方面对照分析首发与复发儿童精神分裂症各 2 8例。结果 :两组在临床核心症状、脑电图检查等方面均无显著性差异 ,均有较高的阳性家族史发生率、脑电图异常率 ,均以思维和行为障碍为其核心症状 ,而较少情感和感知障碍 ,均有较高比率患者使用电休克治疗 ,药物治疗均以不典型抗精神病药物为主。结论 :相对于复发组 ,儿童首发精神分裂症没有显著的临床特点。在作出肯定诊断之后应予以及时、正规的治疗 ,这对于儿童首发精神分裂症具有重要的现实意义。

Objective To study efficacy and safety of risperidone in the treatment of childhood patients with first episode schizophrehia.Methods 70 patients with first episode schizophrenia(age<14 years)were included in this 6 week open clinical study.The positive and Negative syndrome scale(PANSS) and brief psychiatric Rating scale(BPRS) derived from the PANSS were used to assess the clinical efficacy.The Treatment emergent side effect scale (TESS) and laboratory tests were used to assess the adverse effects.Scales...

Objective To study efficacy and safety of risperidone in the treatment of childhood patients with first episode schizophrehia.Methods 70 patients with first episode schizophrenia(age<14 years)were included in this 6 week open clinical study.The positive and Negative syndrome scale(PANSS) and brief psychiatric Rating scale(BPRS) derived from the PANSS were used to assess the clinical efficacy.The Treatment emergent side effect scale (TESS) and laboratory tests were used to assess the adverse effects.Scales were evaluated at baseline and the end of 1、2、4、6.Descriptive analsysis and paired t test were performed in statistical analysis.Results 70 valid cases were collected,among the 70 patients,34.3% met the criteria of complete relief,45.7% significantly improved,10% improved,and 10% got no change.There were significant differences existed in total BPRS scores,total PANSS scores and factor scores of PANSS after 6 week treatment of risperidone.Risperidone showed good effect on the positive,negative as well as general psychopathological symptoms of childhood patients with first episode schizophrenia.The main side effect was slight EPS.Conclusion This study suggests that risperidone is an effective and safe antipsychotic in the treatment of childhood patients with first episode schizophrenia.

目的 了解利培酮治疗儿童期首发精神分裂症患者的疗效和安全性。方法 对 70例年龄 <1 4岁首次发病患儿用利培酮治疗 6周 ,以阳性和阴性症状量表 ( PANSS)和简明精神病评定量表 ( BPRS)评定临床疗效。以副反应量表 ( TESS)和实验室监测评价安全性 ,于基线时 ,实验第 1、2、4、6周末分别评定各量表。统计方法为描述性分析和配对 t检验。结果 共收集有效病例 70例 ,其中基本痊愈 3 4.3 % ( 2 4/ 70 ) ,显著进步 45 .7% ( 3 2 / 70 ) ,好转 1 0 % ( 7/ 70 )和无效 1 0 % ( 7/ 70 )。 BPRS总分、PANSS总分、PANSS各分量表分治疗前后比较均有显著性差异 ( P<0 .0 1 ) ,利培酮对阳性、阴性症状以及一般精神病性症状均有良好疗效。副反应主要为锥体外系反应。结论 对儿童期首发精神分裂症 ,利培酮疗效较好 ,安全性高

Objective:To study the efficacy and safety of risperidone in treatment of childhood patients with first-episode schizophrenia. Method:40 outpatients with schizophrenia (age< 14 years) were treated with risperidone for 8 weeks.The efficacy was evaluated with the brief psychiatric rating scale (BPRS) .The safety was evaluated with the treatment emergent symptom scale (TESS) and the laboratory testing. Results: The average therapeutic dosage of risperidone was (2.84 ±0.71)mg/d,the total efficacious rate was 87.5%...

Objective:To study the efficacy and safety of risperidone in treatment of childhood patients with first-episode schizophrenia. Method:40 outpatients with schizophrenia (age< 14 years) were treated with risperidone for 8 weeks.The efficacy was evaluated with the brief psychiatric rating scale (BPRS) .The safety was evaluated with the treatment emergent symptom scale (TESS) and the laboratory testing. Results: The average therapeutic dosage of risperidone was (2.84 ±0.71)mg/d,the total efficacious rate was 87.5% .The main side effect was slight EPS. Conclusion: It suggested that risperidone is an effective and safe antipsychotic in the treatment of childhood patients with schizophrenia.

目的:了解利培酮治疗儿童期首发精神分裂症患者的疗效及安全性。 方法:对40例年龄<14岁患儿以利培酮治疗8周,以简明精神病评定量表(BPRS)评定疗效,以副反应量表(TESS)及实验室监测评价安全性。 结果:利培酮平均治疗剂量为(2.84±O.71)mg/d,总有效率为87.5%,不良反应主要为锥体外系反应。 结论:对儿童期首发精神分裂症,利培酮疗效较好,安全性高。

 
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