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神经元凋亡     
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  neuron apoptosis
     Rapamycin inhibited PP90RSK and HO-1-mRNA, increased neuron apoptosis and decreased neuron viability(vs group D12,P<0.05 or P<0.01).
     R组PERK1/2蛋白表达变化不明显(vsD12组,P>0.05),PP90RSK表达降低,HO-1-mRNA表达降低,神经元存活率降低,神经元凋亡率增加(vsD12组,P<0.05或P<0.01)。
短句来源
     There was positive correlation between expression of Bax and neuron apoptosis(P<0.05).
     Bax的表达与神经元凋亡呈正相关(P<0.05);
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     ③ The median ratio of neuron apoptosis in hippocampus CA1 in group Ⅲ was 0.83/HP,significantly lower than group Ⅱ(1.50/HP,P<0.01),but higher than group Ⅰ(0.50/HP P<0.01).
     ③组Ⅲ仔鼠海马CA1区神经元凋亡率中位数为0.83个/HP,低于组Ⅱ(1.50个/HP,P<0.01),高于组Ⅰ(0.50个/HP,P<0.05)。
短句来源
     U-0126 inhibited PERK1/2 , PP90RSK and HO-1-mRNA, increased neuron apoptosis and decreased neuron viability(vs group D12,P<0.05 orP<0.01).
     U组PERK1/2和PP90RSK表达降低,HO-1-mRNA表达降低,神经元存活率降低、神经元凋亡率增加(vsD12组,P<0.05或P<0.01)。
短句来源
     Influence of 2DG on Neuron Apoptosis and Expression of Caspase-9 and Caspase-12 of Neuron in Fetal Distress Rat
     2DG对宫内窘迫胎鼠神经元凋亡及caspase-9,-12蛋白表达的影响
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  neuronal apoptosis
     Effect of NF-κB,Bcl-2 and Bax on neuronal apoptosis in experimental presyrinx state
     实验性脊髓空洞前状态神经元凋亡及NF-κB,Bcl-2和Bax的调控作用
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     The ratio of neuronal apoptosis in the cortex in the treatment group was lower than FGR group(2.98±0.54/HP vs 5.05±1.17/HP, P<0.01), but higher than the control group(2.3±0.69/HP, P<0.01).
     (2)皮层神经元凋亡率:治疗组低于FGR组[分别为(2.98±0.54)个/高倍视野和(5.05±1.17)个/高倍视野,P<0.01],但高于对照组[(2.3±0.69)个/高倍视野,P<0.01]。
短句来源
     Role of Voltage-dependent Potassium Channels in Aβ_(25-35)-induced Neuronal Apoptosis and the Relevant Pharmacological Study
     电压依赖性钾通道在Aβ_(25-35)诱导的神经元凋亡中的作用及相关药理学研究
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     Effect of Calpain inhibitor-3 on Caspase-3 expression and neuronal apoptosis in hippocampal CA1 region of neonatal rats after hypoxic-ischemic brain damage
     Calpain抑制剂-3对新生大鼠脑缺氧缺血后海马CA1区Caspase-3表达和神经元凋亡的影响
短句来源
     (2)The ratio of neuronal apoptosis in hippocampus in each group was statistically different (H= 34.88,P<0.01).
     ②3组仔鼠海马CA1区神经元凋亡率差异有统计学意义(H=34.88,P<0.01)。
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  neurons apoptosis
     IGF-1 protection against cerebellar granule neurons apoptosis induced by diphenylhydantoin through a PI3K/Akt dependent pathway
     IGF-1经PI3K/Akt依赖性途径保护苯妥英诱导的小脑颗粒神经元凋亡
短句来源
     Overexpression of Fas/Fasl,P38MAPK,CHOP contributes to ischemia-induced neuronal cell death and is presumedly involved in mechanism of signal conduction in ischemia neurons apoptosis.
     Fas/Fasl、P38MAPK、CHOP等基因的过表达诱导缺血神经元的凋亡,可能参与缺血神经元凋亡的信号传导机制。
短句来源
     Conclusions Phosphatidylinositol 3-kinase/AKT signal pathway is involved in anti-apoptosis action produced by sodium ferulate in β-amyloid peptide(25-35)-induced cortical neurons apoptosis.
     结论在Aβ25-35诱导大鼠皮层神经元凋亡模型中,PI-3K/Akt信号转导通路参与了阿魏酸钠的抗凋亡作用。
短句来源
     Effects of Carthamus tinctorius injection on bcl-2,caspase-3 expression related to neurons apoptosis after local cerebral ischemia
     红花注射液对大鼠局灶性脑缺血后梗死体积和神经元凋亡相关蛋白bcl-2,caspase-3表达的影响
短句来源
     Conclusion:The occurrence of neurons apoptosis is related to the increase in Fos and Jun expression in cultured hippocampal neurons after anoxia/reoxygenation.
     结论 :缺氧 /复氧后即早反应基因fos在神经元中的持续表达可引起神经元凋亡 ,原癌基因jun的表达与神经元凋亡的发生有关
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  apoptosis of neuron
     Effect of intraventricular administration of insulin on expression of Bcl-2 protein and the apoptosis of neuron in rat hippocampal CA1 region
     脑室内注射胰岛素对大鼠全脑缺血后海马CA1区Bcl-2蛋白表达及神经元凋亡的影响
短句来源
     As we all known the bcl-2 family protein plays an important role in the apoptosis of neuron death,including the antiapoptotic protein bcl-2、bcl-xL、 Mcl-1 and the proapoptotic protein bax、bix etc.
     bcl-2家族蛋白在神经元凋亡中起重要的作用,包括抑制凋亡的bcl-2、bcl-xL 、Mcl-1和促进凋亡的bax、bix等。
短句来源
     The effect of intraventricular administration of insulin on expression of Bcl-xL protein and apoptosis of neuron in rat hippocampal CA1 region
     脑室内注射胰岛素对全脑缺血后大鼠海马CA1区Bcl-xL蛋白表达及神经元凋亡的影响
短句来源
     Effect of hyperbaric oxygen on apoptosis of neuron in the CA1 area of hippocampus following forebrain ischemia-reperfusion
     高压氧对脑缺血再灌注海马CA_1区神经元凋亡的作用(英文)
短句来源
     AIM To investigate the mechanism of neuroprotective effect of insulin on hippocamal CA1 region, the expression of Bcl 2 protein and the apoptosis of neuron in rat hippocampal CA1 region following global brain ischemia were observed.
     目的 观察胰岛素对全脑缺血后海马 CA1区神经元凋亡及 Bcl- 2蛋白表达的影响 ,探讨胰岛素对全脑缺血后海马CA1区神经元产生中枢直接保护作用的机制 .
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  neuron apoptosis
These data demonstrated that thrombin induced hippocampal neuron apoptosis in a dose-dependent manner through activating protease-activated protein-1 (PAR-1).
      
Effects of L-Tetrahydropalmatine on neuron apoptosis during acute cerebral ischemia-reperfusion of rats
      
The condition of neuron apoptosis, the survival state of neuron, pathological changes under an electron microscope and the number of HSP70 positive cells were measured in all groups.
      
Role of mitochondria in neuron apoptosis during ischemia-reperfusion injury
      
The BDNF may reduce neuron apoptosis through increasing the expression of the bcl-2 anti-apoptosis protein and inhibiting intracellular calcium overload.
      
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  neuronal apoptosis
Positional cloning strategies have revealed several gene candidates including the genes for the survival motoneuron (SMN) and the neuronal apoptosis inhibitory protein (NAIP).
      
Study of Survival of Motor Neuron (SMN) and Neuronal Apoptosis Inhibitory Protein (NAIP) gene deletions in SMA patients
      
Recent discovery of neuronal apoptosis following in utero AED exposure in animals during a period that corresponds to the third trimester and early infancy in humans raises further concerns.
      
To investigate the role of mitochondria in neuronal apoptosis, ischemia-reperfusion mediated neuronal cell injury model was established by, depriving of glucose, serum and oxygen in media.
      
Expression profiling of p53-target genes in copper-mediated neuronal apoptosis
      
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  neurons apoptosis
In this study, it was shown that treatment with various doses of preaggregated A1-40 for 24 to 72 h could all result in cortical neurons apoptosis.
      
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