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卡介苗
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  bcg
    Protection of mice against Plasmodium berghei with BCG
    用死卡介苗保护小白鼠防止柏氏鼠疟原虫(P.berghei)感染
短句来源
    Studies on Immune Persistence of the Lyophilized BCG
    冻干卡介苗免疫持久性观察
短句来源
    Study on Persistence of Anti-HBs of Separate or Simultaneous Administration of Hepatitis B Vaccine and BCG
    乙型肝炎疫苗和卡介苗同时或分别接种的抗-HBs持久性
短句来源
    The Research on Deer Immune Responseto BCG and the Best Immune Method
    梅花鹿对卡介苗的免疫应答及最佳免疫方法的研究
短句来源
    Theoretical and methodological aspects of BCG vaccine from the discovery of Calmette and Guerin to molecular biology. A review
    卡介苗的理论和方法学两个方面的情况综述——从Calmette和Guérin的发现到分子生物学
短句来源
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  bcg vaccine
    Theoretical and methodological aspects of BCG vaccine from the discovery of Calmette and Guerin to molecular biology. A review
    卡介苗的理论和方法学两个方面的情况综述——从Calmette和Guérin的发现到分子生物学
短句来源
    Construction, Expression and Identification of a Recombinant BCG Vaccine Encoding Human Mycobacterium tuberculosis Heat Shock Protein 65
    人结核杆菌热休克蛋白65重组卡介苗疫苗的构建、表达及鉴定
短句来源
    Construction of A Recombinant BCG Vaccine Expressing the Secretory Form Fusion Protein 85B-ESAT-6
    分泌性表达融合蛋白85B-ESAT-6重组卡介苗的构建和表达
短句来源
    The BCG group and the BCG-tuberculosis group were injected with the live BCG vaccine 0.01mg in the abdominal derma at the beginning, after three months the normal control group and the BCG-tuberculosis group were injected in the tail vein with standard person type Mycobacterium tuberculosis H37Rv 0.01mg.
    卡介苗组及卡介苗结核菌组腹部皮内接种活卡介苗(BCG)0.01mg, 三个月后结核菌组及卡介苗结核菌组经尾静脉注入标准人型结核菌株H37Rv 0.01mg;
短句来源
    Results T lymphocyte subsets is no significant difference between the BCG vaccine inoculated group and the non-BCG vaccine inoculated group( P>0.05).
    结果 外周血T淋巴细胞亚群组间比较:前三个月,接种卡介苗组与非接种卡介苗组间T淋巴细胞亚群无显著性差异(P>0.05)。
短句来源
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  bacillus calmette-guerin
    Effects of Bacillus Calmette-Guerin vaccination on immune functional development of splenic T cell in neonatal mice
    新生期小鼠卡介苗接种对脾脏T细胞功能亚群发育的影响
短句来源
    Effect of Bacillus Calmette-Guerin(BCG) Vaccine or(/and) Tubercle Germs on Rat T Lymphocyte Subsets of Peripheral Blood
    卡介苗与结核菌对大鼠外周血T 淋巴细胞亚群的影响
短句来源
    Objective To observe dynamically the effect of Bacillus Calmette-Guerin (BCG) vaccine or(/and) Mycobacterium tuberculosis on rat T lymphocyte subsets of peripheral blood and compare with T lymphocyte subsets of lung tissues, and evaluate the immunological function of BCG vaccine and the immunological impairment of Mycobacterium tuberculosis.
    目的: 观察卡介苗或结核菌对大鼠外周血T淋巴细胞亚群的影响并与肺组织T淋巴细胞亚群作比较,并探讨卡介苗的免疫保护作用及结核菌对免疫的损害。
短句来源
    Bacillus Calmette-Guerin (BCG),a live attenuated bovine tubercle bacillus,is the most widely used vaccine in the world and is also a useful vaccine vehicle for delivering protective antigens of multiple pathogens.
    卡介苗(BCG)是全球应用最广泛的疫苗,也是一种能携带多种致病菌保护性抗原表达的疫苗载体。
短句来源
    In this study,the comparison of clinical effects was carried out about mycobacterium bovine bacillus Calmette-Guerin (BCG)and its components,including polysaccaride nucleic acid(BCG-PSN)and heat shock protein 65(HSP65),on the maturation of cord blood monocyte-derived dendritic cells(DCs). Because they can help us to understand the BCG and its components effects on the neonatal immunefunction.
    通过比较卡介苗 (BCG)、卡介苗多糖核酸提取物 (BCG_PSN)以及热休克蛋白65(HSP65)对脐血单核细胞转化的树突状细胞成熟的影响 ,以探讨BCG及其有效成分对新生儿免疫功能的作用。
短句来源
  “卡介苗”译为未确定词的双语例句
    Kinetics of rBCG_initiated T Cell Immune Responses Monitored by ELISPOT Assay
    应用ELISPOT试验测定重组卡介苗诱导的T细胞应答
短句来源
    Inerleukin-2 (IL-2) was used as adjuvant to BOG and guinea pigs were used as the experimental animals in the study.
    本实验以卡介苗(BCG)作为抗原,以白细胞介素2(IL-2)作为免疫佐剂注射敏感动物豚鼠。
短句来源
    SDS PAGE showed its M r of 21×10 3 to 29×10 3. The enhanced expression of hBD 1 mRNA was dose and time dependent.
    卡介苗胞壁蛋白SephadexG 15 0层析所得 6个组分中 ,组分 5 [相对分子质量 (Mr)范围在 2 1× 10 3~ 2 9× 10 3]诱导SPC A 1细胞hBD 1mRNA的表达增强 4倍 ,其培养上清的抗菌活性显著增强。
短句来源
    Objective Eukaryotic express plasmid of Murine IL-2(pCDNA 3IL-2) and eukaryotic express plasmid of Murine IL-3(pCDNA 3IL-3) were used as adjuvants in the study.
    目的 研究白细胞介素 - 2 (IL - 2 )和白细胞介素 - 3(IL - 3)真核表达质粒的佐剂活性 ,从而达到增强卡介苗 (BCG)免疫效果的作用。
短句来源
    Methods: A gene fragment encoding the cell wall-associated region of 19 000 antigen of mycobacteria and other gene fragment encoding 27 000 protein of C. burnetii were amplified by PCR from genomic DNA, and then were inserted into the XbaⅠ/BamHⅠ sites and the BamHⅠ/HindⅢ sites of E. coli-mycobacteria shuttle vector pSMT3, respectively.
    方法:用PCR技术从卡介苗基因组扩增分枝杆菌 19 000抗原的细胞壁结合区基因和从贝氏柯克斯体基因组扩增 27 000外膜蛋白基因,将它们分别插入大肠杆菌-分枝杆菌穿梭质粒 (pSMT3)的XbaⅠ /BamHⅠ和BamHⅠ /HindⅢ位点。
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  bcg
Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladder cancer.
      
Therefore, current studies aim at developing recombinant BCG (rBCG) strains secreting Th1-like cytokines to improve the effectiveness of the therapy.
      
Peripheral blood monocytes (PBMC) were stimulated by recombinant BCG and transformed into bacilli Calmette-Guerin activated killer (BAK) cells, and the effect of anticancer BAK cells was studied.
      
Recombinant IFN-α-2b-BCG, wild-type BCG (wBCG), wild-type BCG and IFN-α-2b were coincubated with PBMCs respectively in vitro, and the proliferation of PBMC was detected with MTT in different time.
      
The result of MTT showed that the proliferation of PBMC in the recombinant BCG group was more powerful than in the other two groups (P >amp;lt; 0.05).
      
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  bcg vaccine
Construction, expression and identification of a recombinant BCG vaccine encoding human mycobacterium tuberculosis heat shock pr
      
The recombinants were electroporated into BCG to construct the recombinant BCG vaccine and induced by heating.
      
Recurrent soft tissue infection following accidental inoculation with BCG vaccine
      
Antitumor activity of two BCG vaccine preparations against the lewis lung carcinoma in mice
      
Two BCG vaccine preparations were prepared following different production methods.
      
更多          
  bacillus calmette-guerin
The expression of foreign gene,Schistosoma Japonicum 26 ku antigen (Sj26GST),in Bacillus Calmette-Guerin (BCG),Mycobacterium CM.
      
Bacillus Calmette-Guerin (BCG) instillation in the bladder results in a massive local inflammatory response that has secondary antitumor properties.
      
Analysis of mucosal bladder leucocyte subpopulations in patients treated with intravesical Bacillus Calmette-Guerin
      
Cytokine production by the human bladder carcinoma cell line T24 in the presence of bacillus Calmette-Guerin (BCG)
      
The study was initiated as an in vitro approach to the situation existing during intravesical bacillus Calmette-Guerin (BCG) instillation in patients with superficial bladder cancer.
      
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The present work demonstrated that when whole body of mice was exposed to acute 60Co irradiation, the intracellular digestive function of chicken erythrocytes by peritoneal macrophages of mice was suppressed.Intracellular digestion tests were carried out in mice 4, 6, 10 and 30 days after 750 rad irradiation. As might be expected, in general, a dose-time-dependent respose pattern was seen from 4 to 10 days, and recovery of the intracellular digestive activity was evident from 10 to 30 days. Thus the 10th day...

The present work demonstrated that when whole body of mice was exposed to acute 60Co irradiation, the intracellular digestive function of chicken erythrocytes by peritoneal macrophages of mice was suppressed.Intracellular digestion tests were carried out in mice 4, 6, 10 and 30 days after 750 rad irradiation. As might be expected, in general, a dose-time-dependent respose pattern was seen from 4 to 10 days, and recovery of the intracellular digestive activity was evident from 10 to 30 days. Thus the 10th day was the day of the greatest suppression.Further studies demonstrated that the relationship of the lethal effect as well as the intracellular digestive indices on the 30th day after irradiation with respect to the dosages of irradiation also showed a linear pattern. With increasing in 60Co irradiation dose, the survival rate and intracellular digestive indices were both decreased.Significant protection existed following lethal exposures of 60Go after preventive and therapeutic BCQ treatment. Thus the intracellular digestion ability of peritoneal macrophages in the mouse vaccinated with BCG was increased distinctly than that of the control group. The intracellular digestive function of the mouse peritoneal macrophage might be considered as an index of non-specific immunological response.

本文研究了射线对小鼠Mφ的损伤作用和卡介苗等菌苗对它的防护效果。结果如下:(1)照射后不同病期(假愈期,极期,恢复期),Mφ吞噬消化功能均受到抑制,以极期抑制最严重,小鼠死亡也达最高峰,随着病情好转而Mφ吞噬消化功能也相应出现升高;(2)随着照射剂量的增大,照射30天后小鼠的活存率与腹腔Mφ吞噬消化指数相应降低,并呈显著相关,r=0.88,回归直线方程为y=1.091+1.0137x,说明该指标能反映机体非特异免疫力强弱 ;(3)卡介苗不论防治或单独治疗均能提高照射小鼠活存率,与该菌苗激活照射小鼠腹腔Mφ吞噬消化功能有关。

77 newborns of HBsAg positive carried mothers were immunized with hepatitis B plasma vaccine within 24 hours after delivery and with BCG on the next day.The positive rate of tuberculin test in these babies at 3 months of age was 92.2% as compared to 93.4% in 8289 babies of non-carried mothers to whom BCG alone was given.The hepatitis B vaccine did not seem to interfere the immunogenicity of BCG.The protective efficacy of the hepatitis B vaccine for preventing perinatal transmission of hepatitis B virus in the...

77 newborns of HBsAg positive carried mothers were immunized with hepatitis B plasma vaccine within 24 hours after delivery and with BCG on the next day.The positive rate of tuberculin test in these babies at 3 months of age was 92.2% as compared to 93.4% in 8289 babies of non-carried mothers to whom BCG alone was given.The hepatitis B vaccine did not seem to interfere the immunogenicity of BCG.The protective efficacy of the hepatitis B vaccine for preventing perinatal transmission of hepatitis B virus in the babies of carried mothers,when used in combination with BCG,ranged between 67-89% The protective efficacy of hepatitis B vaccine for babies of carried mothers,when used alone,was estimated to be 71-74%,as it was reported elsewhere.Thus,the use of BCG did not interfere the immunogenicity of hepatitis B vaccine.

本文观察HBsAg阳性孕妇77例,其新生儿生后当天接种乙肝疫苗,次日接种卡介苗;同期HBsAg阴性孕妇的新生儿8,289例,单接种卡介苗。3个月时结核菌素试验阳转率分别为92.2%、93.4%。卡介苗在乙肝疫苗后接种无干扰作用。

Immune effects and reactions of lyophilized BCG were studied using li- quid BCG as control in 1985.Immune persistence produced by inoculation with BCG werestudied in 361 subjects,179 and 182 of them had been vaccinated with lyophilized BCG and liquid one separately.OTconversion rates were 59.22% and 64.29% respectively (x~2= 0.9815).The results showed that the immune persistence of the two types of BCG have no signifficant difference and lyophilized BCG can maintain reliable immunity at le- ast 4 years.By making...

Immune effects and reactions of lyophilized BCG were studied using li- quid BCG as control in 1985.Immune persistence produced by inoculation with BCG werestudied in 361 subjects,179 and 182 of them had been vaccinated with lyophilized BCG and liquid one separately.OTconversion rates were 59.22% and 64.29% respectively (x~2= 0.9815).The results showed that the immune persistence of the two types of BCG have no signifficant difference and lyophilized BCG can maintain reliable immunity at le- ast 4 years.By making a further analysis on reaction intensity,5~14mm of mean di- ameter for the indurations were found as 97.17% and 96.58% of the 2 groups respec- tively.It indicated that the form of BCG have little influence upon its immune pers- istence due to strengthening in the natural infections of TB.

笔者曾于1985年以效果肯定的液体卡介苗为对照,对冻干卡介苗进行了接种效果与接种反应的观察。在此基础上,4年后,剔除各种因素所致的失访者,又对现存的361名观察对象进行了免疫持久性观察,结果,179名冻干苗接种者阳转率为59.22%,182名液体苗接种者阳转率为64.29%,两者无显著性差异(X~2=0.9815);两苗阳转情况与4年前相比,X~2值分别为0.1119和0.2543,P 均大于0.05,显示两苗的免疫持久性相似,至少在4年中可维持可靠的免疫力。进一步分析其反应强度,可见两者硬结平均直径分别有97.17%和96.58%集中在5~14mm之间,似可说明,卡介苗初免成功后,由于自然感染的作用可加强卡介苗诱导的免疫,所以,在免疫持久性方面,不同的卡介苗剂型均无差异。

 
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