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代谢物
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  metabolite
    Studies on Urine Concentrations of TNT and Its Metabolite
    TNT作业工人尿中TNT及其代谢物含量的研究
短句来源
    Study on Correlation between Chromosome Aberration and Metabolite in Urine of Styrene Exposed Workers
    苯乙烯作业工人染色体畸变率与尿中代谢物相关性研究
短句来源
    Determination of MDMA and its metabolite in urine by capillary electrophoresis with high frequency conductivity detection
    毛细管电泳高频电导法测定尿中MDMA及其代谢物
短句来源
    The GC-MS results were consistent with the metabolite profile of Shachongshuang and nereistoxin.
    GC-MS的分析结果与杀虫双及沙蚕毒素的鼠尿代谢物轮廓相符。
短句来源
    Methods Relationship between air concentrations of trinitrotoluene(TNT)at workplaces,urine levels of TNT,4 amino 2,6 dinitrotoluene(4A)and 2 amino 4,6 dinitrotoluene(2A),metabolite of TNT,in the exposed workers was analyzed.
    方法对车间空气中TNT浓度与接触者尿中TNT、代谢物4氨基2,6二硝基甲苯(4A)和2氨基4,6二硝基甲苯(2A)含量的相关性进行了分析。
短句来源
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  its metabolite
    Studies on Urine Concentrations of TNT and Its Metabolite
    TNT作业工人尿中TNT及其代谢物含量的研究
短句来源
    Determination of MDMA and its metabolite in urine by capillary electrophoresis with high frequency conductivity detection
    毛细管电泳高频电导法测定尿中MDMA及其代谢物
短句来源
    Results Urine levels of TNT and its metabolite correlated significantly to air concentrations of TNT at workplaces,especially 4A and 2A.
    结果尿中TNT及其代谢物含量与空气中TNT浓度显著相关,尤其是4A和2A。
短句来源
    Objective To study the effect of dimethoate on the monoamine neurotransmitters, including norepinephine(NE), epinephine(E), serotonin(5-HT), dopamine(DA) and its metabolite (3,4-hydrox-yphenylaceticacid, DOPAC) in the serum of rats and furthermore to explore the non-cholinerigic mechanism of organophosphate induced toxicity.
    目的观察乐果染毒对大鼠血清单胺类递质去甲肾上腺素(NE)、肾上腺素(E)、5-羟色胺(5-HT)、多巴胺(DA)及其代谢物3,4-二羟苯乙酸(DOPAC)浓度变化的影响,探讨乐果中毒的非胆碱能机制。
短句来源
    Result of the study showed thatthe time-plasma Omethoate and its metabolite concentration cuvefitted well to a two compartment open model.
    结果表明,氧乐果及其代谢物在大鼠血中的动态分布规律符合二室开放模型。
短句来源
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  “代谢物”译为未确定词的双语例句
    Results The concentrations of DA(28%-122% of control)and DOPAC(89%-538% of control) varied according with the DM dose and the exposure time.
    DA及其代谢物DOPAC在纹状体分别增加了28%~122%、89%~538%; DA在其它分区变化差异没有显著性。
短句来源
    Changes of contents of urinary metabolism of monoamine neurotransmitter in rats exposed by aluminum.
    染铝大鼠尿中单胺类神经递质代谢物含量的变化
短句来源
    Quantitative analysis of metabolize CDX( QCA and Desoxy-CDX)in pork and swine liver with LC/MS mothod
    LC/MS法猪肉及猪肝中卡巴氧的代谢物(喹喔啉-2-羧酸和脱氧卡巴氧)的定量
短句来源
    Rapid Detection of Malachite Green and its Residues in Aquatic Products
    水产品中孔雀石绿及其代谢物残留量快速检测方法研究
短句来源
    Among DDT, the ratio for pp'-DDE, pp'-DDD and pp'-DDT were 46.2%, 34.6% and 9.9%, respectively.
    pp~1—DDT的代谢物pp~1—DDE和pp~1—DDD分别占DDT含量的46.2%和34.6%,而pp~1—DDT仅占9.9%。
短句来源
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  metabolite
The pharmacokinetics of α- and β-diastereomers of Arteether, a well-known antimalarial drug and its active metabolite dihydroartemisinin (DHA) were studied in Sprague-Dawley rats, Rhesus monkeys and human volunteers.
      
Biological Evaluation of a Secondary Metabolite, 9-O-methylfusarubin, from Fusarium oxysporum
      
Surprisingly, in the corresponding control set (cultivation of laccase-negative clone without atrazine) an unidentified metabolite having a retention time and UV-spectrum similar to those of atrazine was also found.
      
It has been demonstrated in model experiments that the decrease in the content of BET in the culture fluid is accounted for by the toxin interaction with an attendant product, the exogenous metabolite (EM).
      
Biotransformation of β-carotene with enzyme preparations isolated from the mycelium of Blakeslea trispora resulted in the formation of its hydroxylated metabolite and apocarotenals, products of oxidative degradation of this compound.
      
更多          
  its metabolite
In all producer strains, the synthesis of these enzymes was induced by arabinose and its metabolite arabitol.
      
Comparison of acute electrophysiological effects of amiodarone and its metabolite desethylamiodarone in Langendorff perfused gui
      
This led to the suggestion that the electrophysiological effects of amiodarone during long-term treatment might be partly the result of the accumulation of its metabolite desethylamiodarone.
      
To clarify whether primidone itself, and not only its metabolite phenobarbitone, suppresses essential tremor, the effect of a high single dose of primidone was tested.
      
The ability of the selective nigral toxin 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine (MPTP) (via its metabolite MPP+) to destroy nigral dopamine cells selectively by inhibiting complex I of the mitochondrial energy chain may provide a clue.
      
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This article summarizes the urine analysis in industrial exposure monitoring which usually relies on the analysis of a metabolite of an exposed organic compound,It can also be used to measure the occupational exposure of inorganic salts.Following problems are discussed, ( 1 ) correlation of exposure with the concentration of the index chemical in urine, (2) biological threshold limit values, (3) analysis for inorganic ions, (4) sample collection and (5) analytical methodology.

本文综合介绍了接触工业化学物后尿液中原化学物及其代谢物的一般测定情况,并对测定中普遍存在的一些问题(尿中化学物的浓度与接触这些化学物的关系、生物阀限值、阴离子的测定、样品的收集、分析方法学等)进行了讨论。

The amount of the skin contami-nation,urinary TNT and its chief me-tabolites were measured in 16 TNT ex-posed workers with different personalprotection.The results showed thatTNT load predicted by urinary deter-mination was mainly from the absorp-tion of the contaminated skin.Com-bining with the low concentration ofair TNT,percutaneous absorption seem-ed an important route of entry,which was verified by the correlationanalysis between dermal and urinarymeasurements,r=0.50.The chronicpoisoning of TNT must be...

The amount of the skin contami-nation,urinary TNT and its chief me-tabolites were measured in 16 TNT ex-posed workers with different personalprotection.The results showed thatTNT load predicted by urinary deter-mination was mainly from the absorp-tion of the contaminated skin.Com-bining with the low concentration ofair TNT,percutaneous absorption seem-ed an important route of entry,which was verified by the correlationanalysis between dermal and urinarymeasurements,r=0.50.The chronicpoisoning of TNT must be chieflycondemned to the cutaneous pollution.Thus,to prevent dermal contamina-tion the effective protect measuresshould be adopted in advance. Therefore,it was suggested thatthe measurement of urinary TNT andits metabolites were the biologicalmonitoring parameter to adequateevaluation of TNT exposure.

本文采用不同个体防护措施,对TNT作业工人的全身皮肤污染总量、尿中TNT及其代谢物进行定量观察。观察表明,现有硝铵炸药生产条件,工人体内TNT负荷主要来自皮肤污染;职业接触TNT,皮肤是主要吸收途径,经皮肤吸收是当前引起TNT慢性中毒的主要原因。本文观察结果为预防TNT慢性中毒,切实采取皮肤防护措施提供了依据。提出测定尿中TNT及其代谢物可作为接触TNT的生物监测指标,进一步研究生物监测指标的限值,对精确估算工人体内TNT的负荷,具有实际意义。

345 workers exposed to TNTwere investigated.The incidence ofcataract was 64.7%,indicating thatit is a sensitive index in screeningand detection of the harmful effectof TNT.Nine percent of them werefound with enlargement of liver.Theactivity of serum LDH in workersexposed was significantly higher thancontrol group.Heinz body in erythro-cytes were found in 36% workersexposed.However 3.1% were onlymild anemia.The metabolites ofTNT in urine were positive in morethan 1/3 exposed workers.Field stu-dy showed that skin...

345 workers exposed to TNTwere investigated.The incidence ofcataract was 64.7%,indicating thatit is a sensitive index in screeningand detection of the harmful effectof TNT.Nine percent of them werefound with enlargement of liver.Theactivity of serum LDH in workersexposed was significantly higher thancontrol group.Heinz body in erythro-cytes were found in 36% workersexposed.However 3.1% were onlymild anemia.The metabolites ofTNT in urine were positive in morethan 1/3 exposed workers.Field stu-dy showed that skin contaminationplays an important role in causingbody injury. In subacute experiment with ratsand rabbits,the changes in hepa-tocytes,especially the injury of mi-tochondria,and elevation of SGOTwere present.But there were pre-vented by oral Vit.E simultaneously.Its protection role may be impedingof lipid peroxidation induced byTNT.

对354名接触TNT工人进行了研完。白内障的发病率为64.7%,表明白内障是筛检TNT毒作用的敏感指标。9%的接触者有肝大。接触组血清LDH活力显著高于对照组.36%接触者发现有Heinz小体,但仅有3.1%患轻度贫血。1/3多工人尿中TNT代谢物测定阳性。现场研究表明皮肤污染是主要途径。对大鼠和兔的亚急性毒性实验证明肝细胞损伤主要是损害线粒体以及SGOT增高。但同时给予维生素E能防止TNT的毒作用。其机制可能与抑制TNT的脂质过氧化作用有关。

 
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