Experiment 1, Establishment and evaluation of animal model about athletic estrous cycle dysfunction:Female SD rats were assigned randomly to training and control groups. Training groups ran on a treadmill according to the protocal by progressive increasing training load manner. Evaluation parameters included body weight, fatigue degree, serum total T and T/C, Hb, BLA, BUN and vagina shedding cells.
This study was monitoring to the HPA axis and anti-productive hormones during the establishment of animal model of athletic estrous cycle dysfunction and 4 recovering cycles. The results showed that hormone levels of HPA axis,hypothalamus,pituitary and plasma β-EP,serum PRL were significantly elevated with training load increasing.
Purpose To explore the change in and the significance of GnRHR gene expression in each segment of HPO axis in rats with exercise-induced estrous cycle dysfunction.