Both lipid peroxidation and fluorescence polarization were used to dertimne the protective action of propolis extract on the effect of rat erythrocyte ghost injury induced by oxygen-centred free radicals.
Three experimental groups were set up: negative control group(24% ethanol),experimental group(0.1 g/L,24% propolis-ethanol extract) and positive control group(0.1 g/L,ferulic acid).
CONCLUSION: Propolis-ethanol extract inhibits platelet activation and reduces its adhesion on fibrinogen and collagen surface,especially in fibrinogen surface.
The present study has been conducted to evaluate the curative effect of propolis extract, a honey bee-hive product, against acetaminophen (APAP) induced oxidative stress and dysfunction in liver and kidney.
Animals were challenged with APAP (2 g/kg, p.o.) followed by treatment of propolis extract (100 and 200 mg/kg, p.o.) once only after 24 h.
Propolis extract successfully reversed the alterations of these biochemical variables at higher dose.
Caffeic acid phenethyl ester (CAPE), an active component of propolis extract, exhibits antioxidant and anti-inflammatory properties.
Duration-dependent hepatoprotective effects of propolis extract against carbon tetrachloride-induced acute liver damage in rats
Seven components have been isolated from Beijing propolis and identified as 5,7-dihydroxyflavone, 3,5,7-trihydroxyffavone, 5,7-dihydroxy-2'-methoxyflavone, methyl tricosanoate. bis(2-ethylhexyl) phthalate, diisobutyl phthalate and di(2-ethylhexyl) decanediate.
Sinapic acid, isoferulic acid, caffeic acid and chrysin were isolated from the alcoholic extraction of propolis and identified by spectrometric methods. The first three compounds were shown with inhibitive effect against Staphylococcus aureus, while ehrysin was ineffective.
The transmissional anaesthetic action of the propylene glycol extract of propolis (PEP) was studied by toad isolated nerve method. The result showed that PEP could block the excitafory, nerve transmission rapidly and effectively, suggesting it had a strong transmissional anaesthetic actoin.