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肾间质     
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  renal interstitial
     The expression of Smurf2mRNA and protein was positively correlated with that of Smad2(r=0.975,0.979,P<0.01),and the index of interstitial fibrosis(r=0.911,0.964,P<0.01)during the progressive phase of renal interstitial fibrosis(RIF).
     ⑵Smurf2 mRNA和蛋白质与肾间质纤维化指数呈正相关(r=0.911,0.964,P<0.01),与肾间质炎性细胞浸润指数无相关,与Sm ad2 mRNA和蛋白呈正相关(r=0.975,0.979,P<0.01)。
短句来源
     Result The index of renal interstitial fibrosis,the expressions of p-Smad2/3,COL-IV and TGF-β1 protein in the renal interstitial,and the expression of TGF-β1 mRNA in renal tissue were decreased significantly in the Cs-4-treated group than those in the UUO model group.
     结果Cs-4治疗组肾小管间质纤维化指数、肾间质COL-IV、TGF-β1和p-Smad2/3的蛋白表达以及肾组织TGF-β1的mRNA表达均较模型组明显降低。
短句来源
     (2) To investigate the effect of 1,25-(OH)_2VitD_3 on the production of fibronectin induced by TGF-β1 in renal interstitial fibroblast.
     (2) 通过观察活性维生素D_3 (1,25-(OH)_2VitD_3,简称活性VitD_3,下同)抑制TGF-β1诱导肾脏间质成纤维细胞合成纤维连接蛋白(Fibronectin简称FN,下同)作用的研究,探讨活性VitD_3阻止肾间质纤维化作用的机理。
短句来源
     Effect of Cordyceps Sinensis on Expression of p-Smad2/3 in Renal Interstitial of UUO Rats
     发酵虫草菌粉Cs-4对UUO大鼠肾间质p-Smad2/3表达的影响
短句来源
     CONCLUSION: IL-18Rα mRNA and IL-18Rβ mRNA are expressed in RTECs, which provide the experimental basis for exploring IL-18R role in renal interstitial fibrosis.
     结论:在RTECs中有IL-18RαmRNA和IL-18RβmRNA的表达,为探讨IL-18R在肾间质纤维化中提供了实验依据的作用。
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  renal interstitium
     Results There were positive correlations between the expressions of CD4+, CD8+ and CD68+ in the renal interstitium and renal tubulointerstitial pathological changes (r_s=0.570,P=0.029;r_s=0.368,P=0.009, r_s=0.468, P=0.003).
     结果 肾间质中CD4+,CD8+,CD68+细胞浸润密度与肾小管间质病变程度呈正相关(rs=0.570, P=0.029;rs=0.368,P=0.009,rs=0.468,P=0.003)。
短句来源
     The expressions of CD8+ and CD68+ in renal interstitium and the prognosis of kidney diseases were correlated (r_s=0.398,P=0.004;r_s=0.328,P=0.036) .
     肾间质CD8+,CD68+细胞的浸润密度与临床转归之间也呈正相关(rs=0.398,P=0.004;rs=0.328,P=0. 036)。
短句来源
     The expression of MCP-1 and TGF-β1 in renal interstitium were detected with immunohistochemistry.
     免疫组织化学染色观察MCP-1和TGF-β1在肾间质中的表达。
短句来源
     The expression of CTGF in the renal interstitium was closely correlated with those of TGF-β1 and collagen type Ⅲ (P<0.01).
     相关分析发现 ,肾间质中CTGF的表达量与TGF β1和Ⅲ型胶原的表达呈显著性正相关 (r =0 63和 0 6g ,P <0 0 1)。
短句来源
     RESULTS: PFP positive expression was found in glomerulus (2/10), renal tubules (3/10) and renal interstitium (7/10).
     结果:在HBV-GN肾组织内perforin在2/10的肾小球表达,3/10在肾小管阳性表达,7/10肾间质表达.
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  renal tubulointerstitial
     Expression of p-Smad2/3 and smad7 in experimental renal tubulointerstitial fibrosis rat model
     p-Smad2/3、Smad7在大鼠实验性肾间质纤维化模型中的表达
短句来源
     Results There were positive correlations between the expressions of CD4+, CD8+ and CD68+ in the renal interstitium and renal tubulointerstitial pathological changes (r_s=0.570,P=0.029;r_s=0.368,P=0.009, r_s=0.468, P=0.003).
     结果 肾间质中CD4+,CD8+,CD68+细胞浸润密度与肾小管间质病变程度呈正相关(rs=0.570, P=0.029;rs=0.368,P=0.009,rs=0.468,P=0.003)。
短句来源
     Changes of PI3K/AKT expression in renal tubulointerstitial fibrasis of unilateral ostruction rats
     单侧输尿管结扎对大鼠肾间质PI3K/AKT表达的影响
短句来源
     Conclusions TGF-β1/Smad signaling is involved in the progression of renal tubulointerstitial fibrosis.
     结论 TGF-β1/Smad信号通路参与了肾间质纤维化进程。
短句来源
     Objective To elucidate the association of renal tubulointerstitial expression of TSP-1(thrombospondin-1) and VEGF(vascular endothelial growth factor) with renal disease in the patients with chronic nephropathy and to evaluate the role of TSP-1 and VEGF in the genesis of chronic renal interstitial fibrosis.
     目的探讨肾脏组织中血小板反应蛋白1(thrombospondin-1,TSP-1)、血管内皮生长因子(vascular endothelial growth factor,VEGF)在肾间质纤维化发生、发展中的表达及意义。
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  renal stroma
     12 h after operation, counts of karyocyte increased markedly in renal stroma in groups of treatment and pretreatment with glycyrrhizin compared with that in sham operation group( P <0.05),and decreased distinctly compared with that in saline treated group( P <0.01), but no significant difference was found between treatment group and pretreatment group( P >0.05);
     术后 12h ,甘草酸治疗组和预防治疗组与假手术组比较 ,肾间质有核细胞计数显著增多 (P <0 .0 5 ) ,与生理盐水组比较显著减少 (P <0 .0 1) ,但在甘草酸治疗组和预防治疗组差异无显著性 (P >0 .0 5 )。
短句来源
     In renal stroma, routine morphological examinations and counts of karyocyte were made, the expression of collagen type Ⅰand type Ⅲ were also detected by immunohistochemical staining,then, semi quantified by EIG image analysis system.
     免疫组织化学染色检测肾间质Ⅰ、Ⅲ型胶原蛋白表达 ,并用EIG综合图像分析系统对其表达进行半定量分析。
短句来源
     Results A progressive fibrosis was observed in renal stroma of the model.
     结果 模型显示肾间质呈进行性纤维化。
短句来源
     The expression of collagen type Ⅰ increased markedly compared with that in sham operation group( P <0.01) in renal stroma, but decreased notably compared with that in saline treated group( P <0.01),while, there was not any difference between treatment group and pretreatment group( P >0.05). The expression of collagen type Ⅲ in renal stroma was almost the same as that of collagen type Ⅰ.
     术后 3d ,甘草酸治疗组和预防治疗组肾间质Ⅰ型胶原蛋白的表达也高于假手术组 (P <0 .0 1) ,但显著低于生理盐水组 (P <0 .0 1) ,而甘草酸治疗组和预防治疗组差异无显著性 (P >0 .0 5 ) ,Ⅲ型胶原蛋白的表达与Ⅰ型胶原蛋白的表达基本一致。
短句来源
     (2) High expression of α SMA, TGFβ 1 and CTGF presented in all patients with ATN, but extra cellular stromal deposit appeared only in the renal stroma of patients with MD ATN, suggesting that its chronical trend might be related with the reducing of extra cellular stromal degradation factor and/or endogenous anti fibrosis factor.
     (2 )MD ATN与A ATN患者肾间质内α SMA、TGFβ1和C
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  renal interstitial
Concentration of antibiotics in renal interstitial fluid, soft tissue interstitial fluid, urine and serum
      
A direct time-concentration relationship of these three structurally unrelated antibiotics in serum and renal interstitial fluid was found.
      
Concentration and protein binding of cephalosporins in renal interstitial fluid, soft-tissue interstitial fluid, urine and serum
      
Antibiotic concentration in renal interstitial fluid was less than urinary levels but exceeded serum concentrations.
      
A direct time-concentration relationship of these three structurally related antibiotics with different protein-binding in serum and renal interstitial fluid was found.
      
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  renal interstitium
This model helps illuminate the basic pharmacokinetics of antibiotic in the renal interstitium where pyelonephritis occurs.
      
The renal interstitium is divided into a perivascular and a peritubular interstitium.
      
This model helps illuminate the basic pharmacokinetics of antibiotic in the renal interstitium where pyelonephritis occurs.
      
The glomerular mesangial proliferation, inflammatory cellular infiltration of renal interstitium and interstitial fibrosis were ameliorated significantly.
      
The number of the apoptototic cells in glomeruli, renal tubule and renal interstitium was remarkably higher in the model group than that in the control group (P>amp;lt;0.05, P>amp;lt;0.01).
      
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  renal tubulointerstitial
Expression of connective tissue growth factor in renal tubulointerstitial fibrosis in rats and its pathogenic role
      
In order to explore the role of connective tissue growth factor (CTGF) in the pathogenesis of renal tubulointerstitial fibrosis, 48 Wistar rats were randomly divided into sham-operated and unilateral ureteral obstruction (UUO) group.
      
The renal tubulointerstitial injury index was evaluated according to the MASSON staining.
      
On the post-UUO day 7, the protein level of CTGF was positively related to the renal tubulointerstitial injury index (r=0.62,P>amp;lt;0.01), the expression of TGF-β1 (r=0.85,P>amp;lt;0.01), col I (r=0.78,P>amp;lt;0.01), and PAI-1 (r=0.76,P>amp;lt;0.01).
      
The role of protease activated receptor-2 (PAR-2) in the renal tubulointerstitial lesion induced by unilateral ureteral obstruction (UUO) was explored.
      
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  renal stroma
Secondly, an enlarging renal cell carcinoma may lead to compression of renal stroma and disappearance of normal parenchyme tissue.
      
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