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环孢素
相关语句
  cyclosporine
    The Efficacy and Safety of Cyclosporine A after Renal Transplantation: A Systematic Review
    肾移植术后应用环孢素A有效性及安全性系列研究的系统评价
短句来源
    The clinical significance of detecting blood concentration of cyclosporine A and β 2 MG in renal transplanted recipients
    肾移植后监测环孢素A血药浓度与β2-微球蛋白的临床意义
短句来源
    Study on the Reversing Effect of Cyclosporine A on Adriamycin-resistant Human Bladder Cancer Cell Line BIU-87/ADM
    环孢素A逆转人膀胱癌耐阿霉素细胞亚株BIU-87/ADM效应的研究
短句来源
    Anti P glycoprotein monoclonal antibody JSB 1 and cyclosporine in overcoming adriamycin resistant human bladder cancer cell line
    抗P-糖蛋白单克隆抗体JSB-1和环孢素A协同逆转人膀胱癌MDR的研究
短句来源
    According to the different immunosuppressive drugs used in the early period after renal transplantation,the patients were classified randomly into two groups:①Mycophenolate group(n =60):the patients were administered with Mycophenolate(trade name:CellCept)of 1.5 g/d plus Cyclosporine A of 2.5-4.5 mg/d plus dehydrocortisone of 10-20 mg/d.
    根据术后应用免疫抑制剂不同按随机数字表法分为两组:①吗替麦考酚酯组60例,使用吗替麦考酚酯(商品名:骁悉)1.5g/d+环孢素A2.5-4.5mg/d+泼尼松10-20mg/d。
短句来源
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  cyclosporin
    A clinical study of neoral formulation of cyclosporin A in renal transplantation
    新剂型环孢素Neoral的肾移植临床研究
短句来源
    EVALUATION OF CYCLOSPORIN A USED TO 36 CASES UNDERGOING RENAL TRANSPLANTATION
    36例肾移植患者术后环孢素A的用药分析
短句来源
    Objective To investigate the feasibility and safety of substituting tacrolimus(FK506) for cyclosporin A(CsA) on delaying the pace of renal dysfunction in patients with biopsy-proven chronic allograft nephropathy(CAN).
    目的:探讨他克莫司(FK506)替换环孢素A(CsA)治疗慢性移植肾肾病(CAN)的有效性及安全性。
短句来源
    THE USE OF CYCLOSPORIN A AFTER KIDNEY TRANSPLANTATION
    环孢素A在肾移植后的应用
短句来源
    Effect of treatment with cyclosporin A on the CyP mRNA expression in children nephropathy
    环孢素A治疗对儿童肾病CyP基因表达的影响
短句来源
更多       
  cyclosporine a
    The Efficacy and Safety of Cyclosporine A after Renal Transplantation: A Systematic Review
    肾移植术后应用环孢素A有效性及安全性系列研究的系统评价
短句来源
    The clinical significance of detecting blood concentration of cyclosporine A and β 2 MG in renal transplanted recipients
    肾移植后监测环孢素A血药浓度与β2-微球蛋白的临床意义
短句来源
    Study on the Reversing Effect of Cyclosporine A on Adriamycin-resistant Human Bladder Cancer Cell Line BIU-87/ADM
    环孢素A逆转人膀胱癌耐阿霉素细胞亚株BIU-87/ADM效应的研究
短句来源
    According to the different immunosuppressive drugs used in the early period after renal transplantation,the patients were classified randomly into two groups:①Mycophenolate group(n =60):the patients were administered with Mycophenolate(trade name:CellCept)of 1.5 g/d plus Cyclosporine A of 2.5-4.5 mg/d plus dehydrocortisone of 10-20 mg/d.
    根据术后应用免疫抑制剂不同按随机数字表法分为两组:①吗替麦考酚酯组60例,使用吗替麦考酚酯(商品名:骁悉)1.5g/d+环孢素A2.5-4.5mg/d+泼尼松10-20mg/d。
短句来源
    ②Mizoribine group(n =52):the patients were administered by combining Mizoribine(trade name:Bredinin,produced by Japanese Xuhuacheng Association)of 200 mg/d plus Cyclosporine A of 2.5-4.5 mg/d plus dehydrocortisone of 10-20 mg/d.
    ②咪唑立宾组52例,使用咪唑立宾(商品名:布累迪宁,日本旭化成株式会社研制)200mg/d+环孢素A2.5-4.5mg/d+泼尼松10-20mg/d。
短句来源
更多       
  “环孢素”译为未确定词的双语例句
    The inhibitory effect of PAF antagonist-BN52021 on CsA induced mesangial cell contraction
    PAF拮抗剂抑制环孢素A诱导的肾系膜细胞收缩作用的研究
短句来源
    Anisodamine in the management of cyclosporine-hepatotoxicity in renal transplant recipients
    肾移植受者环孢素肝毒性应用山莨菪碱的临床研究
短句来源
    ProtectiveeffectofMg2+onrenalhemodynamicofisolatedperfusedratkidneywithcyclosporineA
    Mg~(2+)对离体灌流环孢素A的大鼠肾脏血流动力学影响
短句来源
    CLINICAL AND PATHOLOGIC MORPHOLOGY STUDY OF CsA NEPHROTOXICITY IN THE PATIENTS WITH RENAL TRANSPLANTATION
    肾移植术后环孢素肾中毒的临床与病理学研究
短句来源
    Early acute rejection after CsA withdrawal in renal transplantation and clinical study on CsA safe withdrawal
    肾移植患者停用环孢素A后近期急性排斥及安全停用环孢素A临床研究
短句来源
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  cyclosporine
The cyclosporine-A-sensitive mitochondrial permeability transition pore in winter wheat at a low temperature and under oxidative
      
Induction of apoptosis by HCA was partially prevented by BAPTA, N-acetylcysteine or cyclosporine A.
      
The study included 25 RT patients (mean 5.4±2.7 yrs after the transplantation, 10 females and 15 males) treated with immune suppressive therapy including cyclosporine A, azathioprine and prednisolone.
      
The edeines analogs were tested in several in vitro and in vivo assays using the mouse model, with edeine B (peptide W1) and cyclosporine A as reference compounds.
      
Expression of TNF-α in monocytes/macrophages was significantly reduced after pretreatment of pigs with cyclosporine or dexamethasone.
      
更多          
  cyclosporin
The rate of the Ca2+ release was proportional to the Ca2+ load, insensitive to cyclosporin A and to Na+, inhibited by La3+, TPP+, Pi, and nigericin, while being activated by spermine.
      
Cyclosporin A prevented the time-dependent decrease in the Ca2+ capacity of mitochondria but did not affect internucleosomal DNA fragmentation.
      
All the effects of FeSO4 + ascorbate were essentially prevented by cyclosporin A, a specific inhibitor of the mitochondrial Ca2+-dependent pore (also known as the mitochondrial permeability transition).
      
We hypothesize that oxidative stress induced in vitro with FeSO4 and millimolar concentrations of ascorbate damages mitochondria by inducing the cyclosporin A-sensitive Ca2+-dependent pore in the inner mitochondrial membrane.
      
Induction of a Ca2+,cyclosporin A-sensitive pore in mitochondria completely suppressed the lucigenin-derived chemiluminescence (LDC).
      
更多          
  cyclosporine a
Induction of apoptosis by HCA was partially prevented by BAPTA, N-acetylcysteine or cyclosporine A.
      
The study included 25 RT patients (mean 5.4±2.7 yrs after the transplantation, 10 females and 15 males) treated with immune suppressive therapy including cyclosporine A, azathioprine and prednisolone.
      
The edeines analogs were tested in several in vitro and in vivo assays using the mouse model, with edeine B (peptide W1) and cyclosporine A as reference compounds.
      
Paclitaxel and cyclosporine A show supra-additive antiproliferative effects on smooth muscle cells by activation of protein kina
      
We intended to establish a pharmacologic concept of synergistic antiproliferative effects on smooth muscle cells (SMC) by using paclitaxel and cyclosporine A at clinically applicable doses.
      
更多          


This article indicates that postoperative serious infection is the dominant everts which caused death after kidney transplantation, especially in case of mixed infection of bacteria, fungus and virus, But the drub intoxication of cyclosporina which involves the nerve system and may manifested as epilepsia. Loss of sigh and consciousness can't be ignored. Once it happens, the prognosis would be grave. We should pay high precaution about it.

本文提示造成肾移植术后死亡的首要原因是严重感染,尤其是细菌、霉菌、病毒混合感染。同时对环孢素(CsA)中毒引起的癫痫、失明、昏迷等神经系统并发症也绝不能轻视,而且一旦发生,预后很差,应高度警惕。

Cyclosporine A(C_sA)was used in 240 cases of re- nal transplantation in our hospital from February,1985 to September,1990.Of the 240 patients,12 were found to develop spontaneous rupture of the grafted kidney(in- cluding 5 cases of renal vascular rupture)with an inci- dence rate of 5%.The etiology,diagnosis and principle of treatment are briefly discussed.

我院自1985年2月——1990年9月,在尸肾移植应用环孢素 A(CsA)240例次中,发现移植肾自发性破裂12例(含移植肾血管破裂5例),发生率为5.0%。本文对其发生原因、诊断及处理原则作简单讨论。

HLA-DR antigen expression was assayed with monoclonal antibody and indirect immunoperoxidase technique in 95 renal grafts from 47 patients.The results showed that the HLA-DR expression on proximal tubules increased after kidney transplantation and was at much higher level in patients with acute or chronic rejection and acute tubular necrosis (ATN) compared with those with“well-to-do”transplant.While the patients with cyclosporin (CsA) nephrotoxicity displayed similar expression of HLA-DR on tubules with “well-to-do”grafts.Interstitial...

HLA-DR antigen expression was assayed with monoclonal antibody and indirect immunoperoxidase technique in 95 renal grafts from 47 patients.The results showed that the HLA-DR expression on proximal tubules increased after kidney transplantation and was at much higher level in patients with acute or chronic rejection and acute tubular necrosis (ATN) compared with those with“well-to-do”transplant.While the patients with cyclosporin (CsA) nephrotoxicity displayed similar expression of HLA-DR on tubules with “well-to-do”grafts.Interstitial HLA-DR expression was very high on all the above-mentioned conditions including rejection,ATN and CsA toxicity.It is concluded that the analysis of HLA-DR antigen expression in renal allo- grafts is of value in the differential diagnosis of rejection,ATN and CsA nephrotoxicity.

应用免疫酶标技术对47例异体肾移植患者的94例次肾活检标本进行 HLA-DR 抗原的检测,并同时做光镜、电镜、免疫病理检查及淋巴细胞亚群的研究.结果显示:肾移植后近曲小管上皮细胞的 DR 抗原表达增加,肾小球的 DR 抗原表达减少;急、慢性排异反应、急性肾小管坏死时,肾小管及肾间质的 DR 抗原表达均明显增加.环孢素中毒时,肾单位的 DR 抗原表达正常,肾间质的 DR 抗原表达增加。肾脏 HLA-DR 抗原表达在肾移植后的变化用于排异反应的诊断、鉴别诊断、预后判断及治疗决策均具有重要意义。

 
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