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类固醇     
相关语句
  steroid
     According to QTL mapping results, pig and human comparative map and physiological or biochemical functions of genes, three candidate genes were selected: MAN2B2 (a-Mannosidase2,B2), RGS12 (regulators of G protein signaling 12) , mSR (membrane steroid receptor).
     根据国内外报道的QTL定位结果、猪-人比较图谱以及基因的生理生化功能,分别选取了三个影响排卵率的候选基因MAN2B2(a-Mannosidase2,B2,a-甘露糖苷酶2,B2),RGS12(regulators of G protein signaling 12,G蛋白信号调节子12)和mSR(membrane steroid receptor,膜类固醇受体)基因。
短句来源
     Steroid 5α-reductase and 5α-reductase type 2 deficiency
     类固醇5α-还原酶及5α-还原酶2型缺陷症研究进展
短句来源
     The signaling function of steroid receptors happens in the Hsp90/Hsp70-based five-proteins complex (Hsp90, Hsp70, Hop, Hsp40 and p23).
     类固醇受体等蛋白质的信号转导作用是在Hsp70、Hsp90为基础的5种蛋白质(Hsp90,Hsp70,Hop,Hsp40和p23)组成的复合体中进行的。
短句来源
     Evaluation on the efficacy of steroid therapy in patients with Guillain-Barre syndrome
     类固醇治疗Guillain-Barre综合征的疗效评价
短句来源
     Molecular Cloning and Expression Analysis of Srd5α2l2: a Novel Mouse Member of Steroid 5 Alpha-reductase Family
     类固醇5-α还原酶样基因Srd5α2l2的克隆及表达分析
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  steroids
     Some ratios of urine steroids such as An/Etio, T/ET, 5α-diol/5β-diol were relatively steady, which were affected less by gender.
     某些类固醇含量的比值 (如An/Etio、T/ET、5α -diol/5 β -diol)较为恒定 ,且受性别因素影响较小
短句来源
     the rate of hepatitis was 39.1%(9/23) in NHL with HBV(+) after steroids containing chemotherapy and 12.8%(5/39) in other solid tumor with HBV(+) after steroids free chemotherapy( P <0.05).
     HBV阳性的NHL患者用含有类固醇激素方案化疗后乙型肝炎发生率 39.1% (9/2 3) ,HBV阳性的其它实体瘤 (肝癌除外 )患者用不含类固醇激素方案化疗后乙型肝炎发生率 12 .8% (5 /39) ,P <0 .0 5。
短句来源
     Compared with untreated SLE patients, SLE patients treated with steroids or steroids plus immunosuppressor significantly suppressed P40 and P19 expression (P<0.01, P<0.05).
     与未经治疗相比,用类固醇激素或类固醇类激素加免疫抑制剂治疗的SLE患者显著抑制P40和P19的表达(P值分别<0.01和<0.05)。
短句来源
     Steroids Hormone and Bone
     类固醇激素与骨
短句来源
     Adrenal steroids in adrenomyeloneuropathy: Dehydroepiandrosterone sulfate, androstenedione and 17α -hydroxyprogesterone
     肾上腺类固醇与肾上腺脊髓神经病变:硫酸脱氢表雄酮、雄烯二酮和17α-羟孕酮
短句来源
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  hydroxysteroid
     Rat 20α Hydroxysteroid Dehydrogenase (20αHSD)Expression in E.coli
     大鼠20α羟类固醇脱氢酶在大肠杆菌中的表达
短句来源
     Molecular Cloning of 5' Flanking Region and Introns of 20 a Hydroxysteroid Dehydrogenase Gene,Structure Analysis and Measurement on their Activities of Regulation Gene Expression
     20α羟类固醇脱氢酶基因5'侧翼区和内含子结构的分子克隆、结构分析及其对基因表达调控活性的测定
短句来源
     Forty eight clones were sequenced,including 16 new genes,10 glutathione-s-transferase genes,5 glutathione peroxidase genes,2 catalase genes,3 hydroxysteroid dehydrogenase genes,4 tyrosine kinase genes,1 thyroid peroxidase-like protein gene,3 genes for cellulose,1 cAMP responsive element binding protein gene and 3 shell biomineralization related genes.
     选取含插入片段大小不同的48个克隆测序,其中有16个新基因,10个谷胱甘肽转移酶的基因,5个谷胱甘肽过氧化物酶基因,2个过氧化氢酶基因,3个羟基类固醇脱氢酶基因,4个酪氨酸激酶基因,1个类甲状腺过氧化物酶蛋白基因,3个纤维素酶基因,1个cAMP效应元件结合蛋白基因,3个贝壳生物矿化相关蛋白的基因。
短句来源
     Oxidatioin reduction reactions of oestrogens and androgens at position C 17 are catalysed by 17β hydroxysteroid dehydrogenases (17β HSDs).
     17β-羟甾脱氢酶(17β-HSD)催化17-酮类固醇与17β-羟类固醇相互转换。
短句来源
     There are two types of 11β hydroxysteroid dehydrogenase (11β HSD). 11β HSD 1 is an oxoreductase interconverting biologically active cortisol and inactive cortisone.
     现已发现两型11β羟基类固醇脱氢酶(11βHSD):11βHSD1为氧化还原酶,催化皮质醇与其代谢产物之间的相互转化;
短句来源
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  steroid therapy
     Evaluation on the efficacy of steroid therapy in patients with Guillain-Barre syndrome
     类固醇治疗Guillain-Barre综合征的疗效评价
短句来源
     Disseminated Kaposi's sarcoma associated with idiopathic CD4+lymphocytopenia and low dose steroid therapy
     播散性Kaposi肉瘤伴特发性CD4+淋巴细胞减少症及低剂量类固醇治疗
短句来源
     Objective To evaluate the efficacy and safety of steroid therapy in patients with Guillain Barre syndrome (GBS).
     目的 评价类固醇治疗 Guillain- Barre综合征 (GBS)的有效性及安全性。
短句来源
     Steroid Therapy Combined With Thymus Irradiation in 22 Patients With Myasthenia Gravis Unresponding to Thymectomy
     类固醇与胸腺放疗联合疗法治疗22例胸腺切除后无效的重症肌无力
短句来源
     Steroid myopathy (SM) occured in 25(12. 3%) of 204 patients with brain tumors who received steroid therapy and most of them developed weakness during the 4th through 7th week of continous steroid treatment.
     在204例用类固醇激素治疗的脑肿瘤病人中,25例(12.3%)发生了类固醇肌病(SM),它主要发生在用类固醇激素治疗后4—7周。
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      steroid
    A gene regulatory mechanism has been proposed in which steroid hormones and certain other drugs bind to nuclear receptor proteins followed by transfer to DNA where they are inserted between base pairs.
          
    Isolation and characterization of a bacterial strain that efficiently degrades sex steroid hormones
          
    A bacterial strain, ZY3, growing on sex steroid hormones as the sole source of carbon and energy was isolated from the sewage treatment plant of a prophylactic steroids factory.
          
    The degradation rate of the sex steroid hormones increased to 87% and 85% after the addition of maltose and peptone, respectively.
          
    The effects of various plant isoprenoids, including mono-, sesqui-, di-, and triterpenoids, sterols, and steroid glycosides, on parasitic nematodes are reviewed.
          
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      steroids
    Among them, the long chain aliphatics, terpenes and steroids, as the representative structure type, were found with percentages of 36.16%, 6.42% and 9.28%, respectively.
          
    Steroids played a main role in the remission of severe UC (61.0%).
          
    An early age of onset, pancolitis, low hemoglobin and serum albumin levels, and the need for intravenous steroids tended to be associated with the need for surgery.
          
    A bacterial strain, ZY3, growing on sex steroid hormones as the sole source of carbon and energy was isolated from the sewage treatment plant of a prophylactic steroids factory.
          
    Correlation between the Structure of Plant Steroids and Their Effects on Phytoparasitic Nematodes
          
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      hydroxysteroid
    The key enzymes involved in modification of the steroid nucleus of sterol-transforming mycobacteria- 3β-hydroxysteroid oxidase (3-OH-SO, EC 1.13.1.2) and 17β-hydroxysteroid dehydrogenase (17-OH-SDH, EC 1.1.1.51)-were isolated and characterized.
          
    A search for analogs of mammalian 20α-hydroxysteroid dehydrogenase (20α-HSD) in the Saccharomyces cerevisiae genome revealed two candidate proteins: Ypr1p (yeast aldo-keto reductase) and Gcy1p (yeast galactose-inducible crystallin-like protein) [3].
          
    3α-Hydroxysteroid Dehydrogenase in Animal and Human Tissues
          
    This review analyzes data on the biological role of 3α-hydroxysteroid dehydrogenase (3α-HSD) in animal and human tissues and describes its main characteristics, mechanism of action, and regulation of activity.
          
    Androstenedione formation is a result of two reactions: 17,20-lyase reaction of 17α-hydroxyprogesterone (ΔD4-pathway) and 3β-hydroxysteroid dehydrogenase/ΔD4,ΔD5-isomerase reaction using dehy-droepiandrosterone as substrate (ΔD5-pathway).
          
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      其他


    (1)The urinary 17-ketosteroids of 139 Chinese males and 147 Chinese females and the 17-ketogenic steroids of 39 Chinese males and 36 Chinese females were determined. (2)The highest daily urinary excretion of 17-ketosteroids of the Chinese of both sexes are at 25 years of age,the mean value for males is 14.46 mg/24hr,and that of females is 12.05 mg/24 hr. (3)The highest daily urinary excretion of 17-ketogenic steroids of the Chinese is at 30-40 years of age with mean value of 16.1 mg/24hr for males,and at 20-30...

    (1)The urinary 17-ketosteroids of 139 Chinese males and 147 Chinese females and the 17-ketogenic steroids of 39 Chinese males and 36 Chinese females were determined. (2)The highest daily urinary excretion of 17-ketosteroids of the Chinese of both sexes are at 25 years of age,the mean value for males is 14.46 mg/24hr,and that of females is 12.05 mg/24 hr. (3)The highest daily urinary excretion of 17-ketogenic steroids of the Chinese is at 30-40 years of age with mean value of 16.1 mg/24hr for males,and at 20-30 years of age with mean value of 15.7 mg/24hr for females. (4)The results were compared with those of Europeans.

    (一)本报告提供了对不同年龄中国男性139人,女性147人尿液17-酮类固醇及男性39人,女性36人尿液生17-酮皮质类固醇排量之测定结果。(二)中国人17-酮类固醇排量最高年龄在25岁左右,男性最高排量平均值为14.46毫克/24小时,女性最高排量平均值为12.05毫克/24小时。(三)中国男性生17-酮皮质类固醇排量最高年龄在30—40岁,最高排量平均值为16.1毫克/24小时。女性生17-酮皮质类固醇排量最高年龄在20—30岁,最高排量平均值为15.7毫克/24小时。(四)将我们在中国人测定之结果与欧洲文献所载之测定结果作了比较及讨论。

    The purpose of the present experiments is to investigate whether Ginseng (人参) the roots of Panax ginseng, C. A. Mey., possesses adrenocorticoid, glycocorticoid or mineralocorticoid actions. The answer is negative according to the following experiments: (1) The Venning's liver glycogen test on fasting adrenectomized mice. (2) The Dorfman's test of resistance to cold stress on adrenectomized rats. (3) The survival time test with adrenectomized rats. It has been found, however, that Ginseng exerted aa inhibiting...

    The purpose of the present experiments is to investigate whether Ginseng (人参) the roots of Panax ginseng, C. A. Mey., possesses adrenocorticoid, glycocorticoid or mineralocorticoid actions. The answer is negative according to the following experiments: (1) The Venning's liver glycogen test on fasting adrenectomized mice. (2) The Dorfman's test of resistance to cold stress on adrenectomized rats. (3) The survival time test with adrenectomized rats. It has been found, however, that Ginseng exerted aa inhibiting effect on the rat's paw anaphylactoid oedema induced by dextran. This inhibiting effect was somewhat reduced by bilateral adrenectomy, herein the pituitary-adrenal system may play a partial rcle.

    本实驗未能証实人参有醣代謝或矿物貭代謝皮貭类固醇样作用。但人参对大白鼠足右旋醣酐性水肿却有显著抑制作用,去腎上腺后这一作用仅有部分減弱,因此人参抑制右旋醣酐性水肿的作用除部分的通过腎上腺皮貭实現它的消炎作用外,尚有其他机制,并对这些可能的机制进行了討論。

    The present study was undertaken to define the relationship between the glycogen content changes and the growth of the levator ani muscle induced by anabolic steroids in the rat and the mouse.The results obtained showed that the increase in weight of the levator ani and bulbocavarnosus muscles was closely related to the potency and dosage of the anabolic steroids.However,there was no parallelism between the glycogen content and the amount of growth of the muscles.In castrated rats and mice,a significant increase...

    The present study was undertaken to define the relationship between the glycogen content changes and the growth of the levator ani muscle induced by anabolic steroids in the rat and the mouse.The results obtained showed that the increase in weight of the levator ani and bulbocavarnosus muscles was closely related to the potency and dosage of the anabolic steroids.However,there was no parallelism between the glycogen content and the amount of growth of the muscles.In castrated rats and mice,a significant increase in weight of the seminal vesicle was elicited by 17-α-methyltestosterone administration,but this increase was not accompanied by a corresponding increase in glycogen content.When the effects of testosterone propionate on the weights and glycogen contents of the levator ani,rectus femoris and tibialis antericus muscles of castrated rats were studed,it was found that testosterone propionate administration resulted in a significant increase in the glycogen content of all three muscles,while only the levator ani of the medicated rats increased significantly in weight.Castration of rats and mice led to a decrease in weight of the levator ani muscle,while the glycogen content of the muscle remained unchanged or even increased.In the intact mice both insulin and cortisone were capable of producing elevation of the glycogen level in the levator ani without inducing growth of the muscle.Besides,in castrated rats testosterone propionate in doses sufficient to induce growth of the levator ani did not affect glucose utilization of the muscle in vitro.

    已有的资料指出,给去势大鼠注射同化类固醇的最初几天内,提肛肌内糖元含量明显增加。随后提肛肌开始迅速生长,而肌糖元含量逐渐减少。本文研究了同化类固醇对去势或正常大鼠与小鼠的提肛肌或 LBM 重量和对肌糖元含量的影响。结果表明,去势小鼠 LBM 生长速度与所给同化类固醇作用强度和剂量大小有关,但LBM 糖元含量与肌肉生长速度无平行关系。大鼠和小鼠去势后提肛肌和 LBM 重量明显减轻,但糖元含量并不减少。胰岛素和可的松可引起小鼠 LBM 糖元明显增加,但肌肉重量并未增长。MT 刺激小鼠精囊的生长,但精囊的糖元含量反而下降。给去势大鼠注射 TP 后,提肛肌、胫前肌和股直肌糖元含量均有显著增加,然而三种肌肉重量与对照组比较,唯提肛肌重量有显著增加。此外,TP 虽促进大鼠提肛肌的生长,而体外试验表明,给药动物提肛肌利用葡萄糖的能力与对照动物并无显著不同。以上结果似可说明,同化类固醇促进肌肉生长的作用非继发于肌糖元含量的增加。至少可以说,同化类固醇促进糖的利用不是引起肌肉生长的主要条件。

     
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