Methods Chose 30 type 2 diabetic patients who diagnosed newly were treated with glucose tolerance test and insulin excitated test before and after CSII for two weeks. The blood glucose,insulin,C-peptide,ΔI30/ΔG30 and Homa-IR were compared.
Methods Eighty-five type 2 diabetic patients were divided into 4 groups and the levels of negative urine protein,positive urine protein(urine protein ±～+++). UmALB was measured by immunonephelometry,TGF-β1 was measured by ELISA,and the data were compared with that of control group.
Methods MCP-1 polymorphism was investigated in 41 cases of normal control subjects and 57 cases of type 2 diabetes patients by technique of the polymerase chain reaction restriction fragment length polymorphism(PCR-RFLP),and the association of MCP-1 polymorphism with type 2 diabetes mellitus was explored,plasma biological and chemical quota were measured at the same time.
【Methods】Sixty eight patients with type 2 diabetes were studied by two methods of intensive insulin therapy,32 patients were treated by continuous subcutaneous insulin infusion(CSII) with insulin pump and 36 patients were treated by multiple subcutaneous insulin Injection(MSII).
[Methods] The selected 98 older patients with type 2 diabetes mellitus were divided into two groups:the observation group,48 patients associated with acute cerebral infarction,and the control group with 50 cases who had not acute cerebral infarction.
METHODS: The levels of MMP-3 and uPAR in plasma were determined by ELISA sandwich method in 26 healthy controls and 39 patients with type 2 diabetes mellitus including 15 complication-free cases and 24 with macroangiopathy.
Methods: Randomized, placebo-controlled, double-blind clinical trial in two parallel groups over 12 weeks; 85 type 2 diabetic patients with serum LDL cholesterol levels ≥ 3.60 mmol/l and without hypolipidemic medication were included in the study.
Cardiovascular disease is a known complication of diabetes, and we aimed to determine if autonomic dysfunction was associated with carotid artery atherosclerotic plaques in type 2 diabetic patients.
Clinical evidence shows that fibric acids reduce coronary atherosclerosis progression in dyslipidemic patients (eg, bezafibrate, gemfibrozil) and in type 2 diabetic patients (fenofibrate).
Therapy with rimonabant is associated with favorable changes in serum high-density lipoprotein and triglycerides, as well as with an improvement in glycemic control among obese type 2 diabetic patients.
Cardiovascular disease (CVD) is a major determining factor of morbidity and mortality in type 2 diabetic patients.
Elevated plasma levels of free fatty acids (FFAs) may contribute to insulin resistance (IR) that is characteristic of type 2 diabetes mellitus.
SNPs of the PSMA6 gene: Investigation of possible association with myocardial infarction and type 2 diabetes mellitus
Objective: To observe the value of HbA1c level evaluating the total daily basal insulin dose by continuous subcutaneous insulin infusion (CSII) in 268 patients with type 2 diabetes mellitus.
Correlation between HbA1c level and total daily dose of insulin in patients with type 2 diabetes mellitus was analyzed.
After describing the components of the endogenous fibrinolytic system and its interactions, this review focuses on the impact on endogenous fibrinolysis by the renin angiotensin system, the kallikrein kinin system, and type 2 diabetes mellitus.