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   腺癌 在 口腔科学 分类中 的翻译结果: 查询用时:0.446秒
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腺癌
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  adenocarcinoma
    ^Observations of clinical pathology and immunohistochemistry on basal cell adenocarcinoma in the salivary gland
    涎腺基底细胞腺癌的临床病理和免疫组织化学观察
短句来源
    Objective: The aim of this study is to observe the expression of mTOR(mammalian target of rapamycin) and P70 S6 kinase(P70 S6K) signal pathway in oral parotid adenocarcinoma.
    目的:研究mTOR/P70 S6K激酶信号通路激活在腮腺腺癌中的作用。
    Results: The expression level of mTOR and P70 S6K increase obviously in oral parotid adenocarcinoma tissue. The expression of Immunological assay is same as the Western-blot.
    结果:免疫组化与Westem印迹分析的结果一致:和正常组织相比,腮腺腺癌中mTOR和P70 S6K的表达明显增加。
    Conclusions: Higher expression of mTOR and P70 S6K may involve in the pathogenesis of oral parotid adenocarcinoma.
    结论:口腔腮腺腺癌mTOR和P70 S6K的表达增加可能是介导腮腺腺癌发生的主要机制之一。
    Methods Immunohistochemical detection of Rb、bcl-2、C-myc and PCNA genetic proteins in tumor tissues of 50 patients with salivary gland cancers(mucoepiodermoid carcinoma 25,adenocarcinoma 25;Uygur patients 20,Han patients 30)and non-tumor 25 as a control specimens.
    方法收集涎腺恶性肿瘤50例(粘液表皮样癌、腺癌各25例,维吾尔族病人20例,汉族病人30例)及正常涎腺组织25例作为对照,分别进行Rb 蛋白、Bcl-2、C-myc 及增殖细胞核抗原(PCNA)单克隆抗体免疫组化检测。
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    THE RELATIONSHIP BETWEEN C-erbB-2 ONCOPROTEIN EXPRESSION AND BIO- LOGICAL BEHAVIOUR IN SALIVARY GLAND ADENOCARCINONMA
    癌基因C-erbB-2蛋白产物的表达与涎腺腺癌生物学行为的关系
短句来源
    Methods: mTOR and P70 S6 kinase were examined by means of SP immunohistochemical technique and Western-blot test.
    方法:用免疫组化方法及Western印迹分析测定腮腺腺癌中mTOR和P70 S6的表达。
    Median,3-year survival times and 5-year survival times and rate were 8.5years,83.3%,and 66.7%.
    涎腺腺癌思者平均发病年龄49.6岁,13例涎腺腺癌患者中位生存时间为8.5年,3年生存牢为83.3%,5年生存牢为66.7%。
    A Study of CEA and CA-50 Levels in Saliva and Serum of Patients with Tumors in Oral Region and Salivary Gland
    口腔及涎腺癌患者唾液与血清中CEA和CA-50含量的研究
短句来源
    Clinicopathological analysis of salivary carcinosarcoma
    涎腺癌肉瘤临床及病理分析
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  adenocarcinoma
The positive rate of FHIT gene expression in normal colorectal tissue, adenoma and adenocarcinoma were 93.75%, 68.75% and 46.25%, respectively.
      
Synchronous rectal adenocarcinoma and anal canal adenocarcinoma
      
Here, we report on the case of a 63-year-old man who presented with an upper-third rectal adenocarcinoma.
      
Five months after resection, he developed an adenocarcinoma in the anal canal.
      
Impact of siRNA targeting pirh2 on proliferation and cell cycle control of the lung adenocarcinoma cell line A549
      
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Transforming growth factor-β(TGF-β)and bone morphogenetic protein(BMP)were related to embryonic development and differentiation of cells. In this study,the expression and distribution of TGF-βand BMP in 60 cases of salivary gland tumors were studied by using immunohistochemistry.The results showed that the staining patterns of TGF-βand BMP were similar,but the fibrous matrix of tumors was pos-itive to TGF-β,not to BMP.Some well-differentiated malignant salivary gland tumors such as acinic cell car- cinoma,and...

Transforming growth factor-β(TGF-β)and bone morphogenetic protein(BMP)were related to embryonic development and differentiation of cells. In this study,the expression and distribution of TGF-βand BMP in 60 cases of salivary gland tumors were studied by using immunohistochemistry.The results showed that the staining patterns of TGF-βand BMP were similar,but the fibrous matrix of tumors was pos-itive to TGF-β,not to BMP.Some well-differentiated malignant salivary gland tumors such as acinic cell car- cinoma,and all benign salivary gland tumors such as pleomorphic adenoma,basal cell adenoma and myoep-itheloma showed strong positive reaction to both BMP and TGF-β,while some malignant salivary gland tu-mors(poorly differentiated)such as adenocarcinoma papillary cyst adenocarcinoma and adenoid cystic carcino-ma were lightly positive.So the expression of BMP and TGF-βmight be associated with the development and malignancy of salivary gland tumors.

转化生长因子β(TGF-β)和骨形成蛋白(BMP)与胚胎发育、细胞分化密切相关.本研究利用多克隆及单克隆抗BMP抗体、单克隆抗TGF-β抗体,通过免疫组化方法,初步观察了11类60例各种唾液腺肿瘤中TGF-β,BMP的表达与分布.结果发现,TGF-β与BMP的分布模式基本一致,只是TGF-β在肿瘤纤维组织基质中呈弥漫性轻度阳性,而BMP则为阴性.多形性腺瘤、基底细胞腺瘤、肌上皮瘤等良性唾液腺肿瘤中TGF-β,BMP呈强阳性,而腺癌、乳头状囊腺癌、腺样囊性癌等恶性唾液性肿瘤中则呈弱阳性.因此,TGF-β,BMP的表达可能与唾液腺肿瘤的发生和细胞分化有关.

Expresion of C-erbB-2 oncoprotein was analyzed with immunohistochemical staining in 50 salivary gland adenocarcinomas and 25 normal salivary gland tissues, Positive staining was found in 2l/50 (42%)of salivary gland adenocarcinomas. All 25 normal salivary glands showed negative staining. Expression of C-erbB-2 oncoprotein was correlated with clinical stage, histologic differentiation and progno- sis of salivary gland adenocarcinomas. This study suggests that a determination of the level of C-erbB-2...

Expresion of C-erbB-2 oncoprotein was analyzed with immunohistochemical staining in 50 salivary gland adenocarcinomas and 25 normal salivary gland tissues, Positive staining was found in 2l/50 (42%)of salivary gland adenocarcinomas. All 25 normal salivary glands showed negative staining. Expression of C-erbB-2 oncoprotein was correlated with clinical stage, histologic differentiation and progno- sis of salivary gland adenocarcinomas. This study suggests that a determination of the level of C-erbB-2 oncoprotein expression may have prognostic value in human salivary gland adenocarcinoma.

应用免疫组织化学方法,对50例涎腺腺癌患者及25例正常涎腺组织中的C-erbB-2癌基因蛋白表达产物进行检测。结果发现:在涎腺腺癌中有2l例显示C-erbB-2蛋白表达阳性反应,而正常涎腺组织均为阴性反应,而且C-erbB-2的表达程度与涎腺腺癌的临床分期、病理组织分化及患者的预后密切相关。提示,癌基因C-erbB-2蛋白表达产物的检测可能对判断涎腺腺癌的恶性程度和预后有一定的意义。

From 1959 and 1989,65 patients with primary malignant tumour of submandibular re-gion, including 18 cases of adenoid cystic carcinoma,16 cases of malignant mixed tumour,14 cases of adenoid carcinoma,10 cases of undiferentiated carcinoma and 7 cases of squamous cell carcinoma,were treated at this hospital by surgery or combined therapy. The 3-and 5-year survivals were 60%and 42.9%, respectively. Those of malignant mixed tumours were somewhat better, being 75%and 61;5%; Submandibular gland excision or regional/elective...

From 1959 and 1989,65 patients with primary malignant tumour of submandibular re-gion, including 18 cases of adenoid cystic carcinoma,16 cases of malignant mixed tumour,14 cases of adenoid carcinoma,10 cases of undiferentiated carcinoma and 7 cases of squamous cell carcinoma,were treated at this hospital by surgery or combined therapy. The 3-and 5-year survivals were 60%and 42.9%, respectively. Those of malignant mixed tumours were somewhat better, being 75%and 61;5%; Submandibular gland excision or regional/elective dissection was used if the tumcxJrs were local and no capsule invasion. Particular attention was given to the identification of perineural invasion, softtissure extension,bone invasion and lymph node metastasis. Wide excision and neck dissection were necessary for above mentioned pathological changes. Combined therapy was important for those patients with posi-tive margin, recurrence,low- or un-differentiation and advanced stage. The main factors affecting sur-vival were local-regional failure.

1959~1989年我院共收治原发于颌下区的恶性肿瘤65例,其中腺样囊性癌18例,恶性混合瘤16例,腺癌14例,未分化癌10例,鳞癌7例。总的3年、5年生存率为60.0%和42.9%。颌下腺恶性肿瘤有包膜外侵犯与无包膜外侵犯,二者的3年、5年生存率分别为59.5%、30.3%和83.3%、72.7%。淋巴结阳性者预后差,与无淋巴结转移相比,其3年、5年生存率为44.0%、11.1%和88.5%、79.2%。T分期越大预后越不好。死亡原因主要是局部。颈部复发和肺转移。治疗以手术为主。如果肿瘤局限,无包膜外侵犯可做颌下或区域清扫。病变范围广并有颈淋巴结转移者,则需行区域广泛切除及颈清扫。手术切缘不净、术后复发、分化差或病期晚者,宜综合治疗。

 
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