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   iga肾病 在 泌尿科学 分类中 的翻译结果: 查询用时:0.084秒
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iga肾病     
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  iga nephropathy
A 17-year-old boy with end-stage renal disease due to IgA nephropathy presented with acute, spontaneous, symptomatic peritoneal dialysis-associated peritonitis without reported break in sterility or PD catheter exit site infection.
      
Wiskott-Aldrich syndrome (WAS) is an X-linked immunodeficiency characterized by thrombocytopenia with small platelets, eczema, recurrent infections, autoimmune disorders, IgA nephropathy, and an increased incidence of hematopoietic malignancies.
      
Glomerular disorders include IgA nephropathy, cryoglobulinemia, amyloidosis, and a lupus-like immune complex glomerulopathy.
      
Large clinical trials have suggested that cigarette smoking is a risk factor for progression of chronic kidney disease in diabetics and nondiabetics, and in polycystic kidney disease, lupus nephritis, and IgA nephropathy.
      
Childhood Henoch-Sch?nlein purpura nephritis and IgA nephropathy: one disease entity
      
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  iga nephritis
Membranoproliferative glomerulonephritis and IgA nephritis have a severe prognosis and do not respond to treatment.
      
Current data suggest that mesangial IgA nephritis is mediated by the mesangial deposition of soluble antigen-IgA class antibody complexes from the circulation.
      
The IgA positive cases often disclosed paramesangial dense deposits, which is one of the characteristics of primary IgA nephritis.
      
Hepatic IgA nephritis exhibited a lower nephritogenicity and a proneness to show mesangial interposition when compared with primary or purpuric IgA nephritis.
      
Arteriolosclerosis frequently occurs in IgA nephritis (IgAN), and it is the hallmark of benign nephrosclerosis (BNS).
      
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  immunoglobulin a nephropathy
Renal expression of intercellular adhesion molecule-1 in immunoglobulin A nephropathy: tubulointerstitial injury and prognosis
      
We aimed to evaluate whether exposure to antigenic foods in early life is associated with a predisposition for immunoglobulin A nephropathy (IgAN).
      
Immunoglobulin A nephropathy (IgAN) is a form of chronic glomerulonephritis of unknown etiology and pathogenesis.
      
Immunoglobulin A nephropathy (IgAN) is the most common form of glomerulonephritis characterized by predominant IgA deposits in glomerular mesangium.
      
Association of a single-nucleotide polymorphism in the immunoglobulin?μ-binding protein 2 gene with immunoglobulin A nephropathy
      
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Thirteen cases of IgA nephropathy were identified by immuno-fluoreoent method on renal biopsies. Clinically, the initial manifestation of all these patients was hematuria, including 7 oases with various degree of proteinuria in addition, but none of them had nephrotic syndrome. Among 18 patients, 6 had lowered creatinine clearance rate, 1, slightly increased urea nitrogen, 3, mild hypertension, 7, elevated serum IgA value and 3, elevation of serum antistreptolysin. Pathologically, the essential changes of glomeruli...

Thirteen cases of IgA nephropathy were identified by immuno-fluoreoent method on renal biopsies. Clinically, the initial manifestation of all these patients was hematuria, including 7 oases with various degree of proteinuria in addition, but none of them had nephrotic syndrome. Among 18 patients, 6 had lowered creatinine clearance rate, 1, slightly increased urea nitrogen, 3, mild hypertension, 7, elevated serum IgA value and 3, elevation of serum antistreptolysin. Pathologically, the essential changes of glomeruli were proliferation of mesangial cells and matrix. The predominant IgA deposition in glomeruli was confirmed by immunofluorecent stain as well as IgG deposition in 4 eases. Electron-dense deposits could be found in mesangial, subendothelial or intramembranous areas of glomeruli under eleotron-mioroscopic examination. The clinical and pathological features, the relation between IgA deposition in glomeruli and serum IgA level, and the treatment and prognosis of the disease were discussed.

本文报道经肾穿刺活组织免疫荧光染色证实的13例免疫球蛋白A(IgA)肾病病例。临床上,患者均以血尿起病,其中7例还伴有不同程度的蛋白尿,但无1例属于肾病综合征。13例中,内生肌酐清除率低于正常者5例,尿素氮轻度升高者1例,血压升高者3例,血清IgA升高者7例,抗“O”升高者3例。病理上,肾小球的病变主要表现为系膜细胞和系膜基质增生,免疫荧光染色证实小球内以系膜区IgA沉积为主,其中4例还伴有免疫球蛋白G(IgG)沉积。电镜下发现电子致密物以系膜区为突出,内皮细胞下或膜内也有稀疏的电子致密物沉积。最后就本病的临床、病理特征、肾小球内IgA。沉积和血清IgA水平的相互关系,治疗及预后等问题作了讨论。

The clinical and pathological features of 307 patients of primary ■glomerulonephritis

本文对307例经肾活检有完整资料的原发性肾小球肾炎患者的临床及病理类型进行分析,从而探讨它们之间的关系。结果:肾小球肾炎10种主要病理类型的分布以系膜增殖性肾小球肾炎居首位,占30.9%,其次为IgA 肾病(18.9%)及局灶性节段性肾小球硬化(14.7%);男女性分别占74.3%及25.7%;各型中患病平均年龄以膜性肾病(37.6岁)为最大;肾病综合征最常见于膜性肾病,占66.67%;反复发作性肉眼血尿则以IgA 肾病居多;40.00%的局灶性节段性肾小球硬化发生高血压;肾功能减退最明显的是局灶硬化和IgA 肾病。实验室检查有助于判断肾小球、肾小管和间质病变的轻重。本文探讨了微小与非微小病变的计算机分型,其分辨率可达90%以上。

In this study, renal biopsy specimens from 150 cases of IgA nephropathy were studied with light-and electron microscopically. Histological lesions from minimal change to diffuse mesangial proliferation were observed. According to the degree of the renal lesions, the 150 cases were divided into 6 subtypes. Proliferation of mesangial matrix was found to be the striking ultrastructural alteration, which often appeared as focal segmental or global proliferation of mesangial cells, as well as marked increase in mesangial...

In this study, renal biopsy specimens from 150 cases of IgA nephropathy were studied with light-and electron microscopically. Histological lesions from minimal change to diffuse mesangial proliferation were observed. According to the degree of the renal lesions, the 150 cases were divided into 6 subtypes. Proliferation of mesangial matrix was found to be the striking ultrastructural alteration, which often appeared as focal segmental or global proliferation of mesangial cells, as well as marked increase in mesangial matrix. Electron-dense deposits were largely localized in mesangial matrix and in suben dothelial regions. However, no positive correlation could be seen between the number of the deposits and the degree of the lesions.

对150例IgA肾病的肾活检标本进行了光镜及透射电镜的形态学观察,[其组织学改变由轻微病变至弥漫性系膜增殖,根据病变的严重程度作者将其分为6个亚型。系膜基质的增生为其突出的超微结构改变,常显示为局灶节段性、球性系膜细胞增殖和显著的系膜基质的增加。电子致密沉着多见于系膜基质及内皮细胞下,这些沉着物的多少与病变的严重程度未见有肯定的联系。

 
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