Seven new Schiff bases have been synthesized by reaction of 4,4,4 trifluoro 1 (2 thienyl) 1,3 butane dione with thiosemicarbazide, thiocarbohydrazide, benzoic hydrazide, o hydroxyaniline, nicotinic hydrazide, p fluoro m chloroaniline, salicylic hydrazide, respectively, and characterized by elemental analysis, IR, 1H NMR and MS.
The preparation of 2(2thienyl)ethylamine by two step reduction method has been put forward ,Vilsmeier reaction of thiophene with N,Ndimethyl formamide in presence of phosphorus osychloride gave 2formylthiophene,the yield is 89.9%,the purity is 99.9%.
Thiophene,as the starting material,was reacted with formaldehyde and hydrogen chloride to give 2 chloromethylthiophene. The object compound,2 (2 thienyl)ethylamine,was synthesized from 2 chloromethylthiophene via substitution,then reducted by LiAlH 4.The reaction of the three steps were carried out under moderate conditions to afford an overall yield of 70%. The method was more suitable for industrial process.
Geometric structures of α-substituted thiophen derivatives were optimized with B3LYP method at 6-31G~* level. Their frontier molecular orbital energy levels and electronic spectra were obtained with TD-DFT method.
The experiment of model gasoline containing 3-methylethiopen or thiophen showed that desulfurization yield was improved with higher temperature, longer reaction time , more oxidazor and catalyst and use of ultrasound .
Desorption of thiophene,benzene and n-octane on NaY or CeY zeolites was studied using an Intelligent Gravimetric Analyzer(IGA). The tests determined the temperature programmed desorption graphes of thiophene,benzene and n-octane on NaY or CeY zeolites at a 15K/min heating rate. Thiophen.
It was found using Fourier transform IR spectroscopy that thiophene rings were the main structural units of the polymer; aliphatic fragments and oxygen-containing groups were also present.
Thiophene adsorption on γ-Al2O3, hydrated titanium dioxide, and Mo-containing catalysts on these supports is studied by IR spectroscopy.
The form of adsorbed thiophene and the composition of surface species on the catalysts depend on the nature of support.
The coking ability of some hydrocarbons (benzene, n-heptane, styrene, methylnaphthalene, durene, and phenanthrene) and heterocyclic compounds (thiophene and indole) under the conditions of hydrotreatment of feed is estimated for an Al-Co-Mo catalyst.
The influence of the capillary condensation of reactants on the poisoning of Pt/SiO2 catalysts by thiophene is studied experimentally for p-xylene hydrogenation at T = 60 and 80°C.
Some new benzenesulfonamides, disubstituted sulfonylureas, and sulfonylthioureas substituted basically with 3-(2-thienyl or 3-pyridyl)-indeno[1,2-c]pyrazol(in)e counterpart were synthesized to be evaluated for their in vitro antitumor activity.
In general, compounds containing the thienyl moiety displayed better antitumor spectra than those containing the pyridyl moiety.
3-Hydroxy-2-(2"-Thienyl)-4H-Chromon-4-one as a Spectrophotometric Reagent for the Trace Determination of Zirconium in an Aqueous
Crystal structure of N-Furfuryl-1-(2-Thienyl)but-3-en-1-ammonium chloride
The crystal structure of (H2L)+Cl-(HL is N-furfuryl- 1-(2-thienyl)but-3-en-1-amine) was studied by X-ray diffraction analysis.
2-N-(4-Aminobenzo-15-crown-5)methylene-2,3-dihydrobenzo[b]thiophen-3-one and its acetyl derivative were synthesized.
The acylation of ortho-substituted (R = OH, OMe, NHTs) 2-arylaminomethylene-2,3-dihydro- benzo[b]thiophen-3-ones with (4-methyl-2-oxobenzo[b]pyran-7-yloxy)acetyl chloride results in formation of the corresponding N-acyl enaminoketones.
The same reaction with 2-(2-hydroxyphenylaminomethylene)-2,3- dihydrobenzo[b]thiophen-3-one gives rise to a tautomeric mixture of acyloxyphenyl and N-acyl enaminoketone isomers.
2-[N-Acetyl-N-(2-fluorenonyl)aminomethylene]benzo[b]- thiophen-3(2H)-one, a Molecular Fluorescent Switch
Thin-layer chromatographic studies of anils derived from 2-thiophen glyoxal.
The transformation of the 2-amino-5-phenylazo-thiophene derivative9 by potassium hydroxide yields the substituted 3-mercapto-pyridazin-6(1H)one10, with sodium ethoxide the 5-phenylhydrazono-2-oxo-thiolen-3-carbonitrile11 is formed.
In the course of an attempted elimination reaction starting from an isothiochromane derivative substituted with an amino-alcohol moiety, a benzo[c]thiophene derivative formed via a rearrangement reaction was isolated unexpectedly.
Alpha-terthienyl, a phototoxic thiophene derivative from species in the Asteraceae reduced feeding and growth of the phytophagous lepidopteran,Euxoa messoria, when incorporated into artificial diets at a concentration of 100 ppm.
For a thiophene derivative the latter direction of the reaction is observed to a substantially smaller degree.
Vibrational spectra and structure of thiophene derivative sulfones