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治疗组
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  treatment groups
    The two treatment groups had difference(P<0.05) or obvious difference with model group(P<0.01).
    各治疗组与模型组相比有差异(P<0.05)或显著差异(P<0.01);
短句来源
    Compared with model group,the levels of TGF-β1 in two treatment groups were obviously decreased(P<0.01).
    与模型组比较,泼尼松治疗组和芪红合剂治疗组大鼠肺组织中TGF-β1含量显著下降(P<0.01)。
短句来源
    METHODS: Eighty-four rats were averagely randomized into 7 groups: null control group (I), prevention group (Ⅱ), treatment control group (Ⅲa), talcid treatment group (Ⅲb group), JWJ treatment groups (treated with 10, 20, and 30 mg/kg; named as Ⅲc, Ⅲd, Ⅲe, respectively).
    方法:将84只SD大鼠随机分为7组,每组12只Ⅰ组为空白对照组,Ⅱ组为预防组,Ⅲa组为治疗对照组,Ⅲb为达喜对照组,Ⅲc,Ⅲd,Ⅲe分别为荆花胃康胶丸10,20,30mg/(kg·d)治疗组.
短句来源
    Results:In comparison with the shame group, the protein levels of α-SMA, ICAM-1 and the mRNA expression of MCP-1 in UUO mice and treatment groups increased significantly, meanwhile Tripterygium Wlilfordii and ACEI could significantly reduce the expression of α-SMA, ICAM-and MCP-1 on levels of protein and gene.
    结果UUO模型组小鼠肾间质纤维化程度以及肾组织α-SMA的表达较假手术组显著增高,肾小管间质中炎细胞浸润亦较假手术组明显增加; 雷公藤多苷各治疗组肾间质纤维化程度、α-SMA和ICAM-1蛋白、MCP-1基因表达均显著低于模型组;
短句来源
    (b)the level of substance P in the treatment groups was significantly lower than that of the model group(P<0.05);
    与模型组比较,3个治疗组P物质含量降低,差异具有统计学意义(P<0.05);
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  treated groups
    TNF-α of XFC treated group were lower than that of model control group(P<0.01) and IL-10 of XFC treated group were higher than that of model control group(P<0.01),but there were no obvious differences among the three treated groups(P>0.05).
    与正常对照组比较,模型对照组IL-10显著降低(P<0.01); 与模型对照组比较,新风胶囊组IL-10显著升高(P<0.01),而与其余2治疗组无显著差异(P>0.05)。
短句来源
    TNFα of XFC treated group was lower than that of model group(P<0.01),and IL-10 of XFC treated group was higher than that of model group(P<0.01),but there was no obvious difference among the three treated groups(P>0.05).
    与正常组比较,模型组IL-10显著降低(P<0.01); 与模型组比较,XFC组IL-10显著升高(P<0.01),而与其余两个治疗组无显著差异(P>0.05)。
短句来源
    Methods NIH/3T3 fibroblasts were divided into 4 groups: normal, model and treated groups with lower and high dosage of SA-B. Except of the normal group, the cells were incubated with 100 pmol/L TGF-β1 for 24 h, and the treated group in-cubated with 1 μmol/L or 10 μmol/L SA-B in 0.5% FBS/M199 at the same time respectively.
    方法NIH/3T3成纤维细胞常规培养后分为正常组、模型组和治疗组。 正常组细胞以含0.5%FBS的M199培养,模型组和治疗组均在相同培养条件下,以100pmol/LTGF-β1刺激24h,治疗组在此基础上再分别以1μmol/LSA-B和10μmol/LSA-B同时温育24h。
短句来源
    Results Compared with the model group A and B,the degree of LF,the positive expressions of TIMP-1 mRNA and the content of collagen typeⅠandⅢin liver tissue in the QYDP intervened and treated groups were significantly lower.
    结果干预组与治疗组大鼠肝纤维化程度、肝组织中Ⅰ型与Ⅲ型胶原和TIMP-1mRNA水平及肝组织中Ⅰ型与Ⅲ型胶原和TIMP-1的阳性表达均分别较模型组与对照组显著减轻与下降。
短句来源
    3 Serum lipid (1)Total cholesterin(TC): The level of TC in therapeutic groups was lower than that in pathology group, p<0.01, and the effect of the high dose group wasbest in all treated groups;
    3 血脂 ①胆固醇(TC):各治疗组TC水平均显著低于模型组,p<0.01,而以高剂量组下降最为明显,p<0.01;
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  “治疗组”译为未确定词的双语例句
    Results: There was a significant difference (P<0.05) in reducing the TXB2 level and raising the 6-Keto-PGF1α level between the high- and low-dose-treated group and the diabetes control group.
    结果:与模型组相比,愈糖舒康大剂量治疗组、愈糖舒康小剂量治疗组在降低糖尿病大鼠的TXB2和升高6-Keto-PGF1α水平方面,均呈现出显著差异(P<0.05)。
短句来源
    Methods:Cultured HPTEC were exposed to TNF-α 5 ng/ml and centella asiatica & emodin for 24 hours,followed by transcriptase-polymerase chain reaction(RT-PCR)and enzyme-linked immunosorbent assay(ELISA)analysis for complement C3 mRNA and protein expression. Results:C3 mRNA and protein production were present in HPTEC.
    方法:采用HPTEC,模型组TNF-α10ng/ml诱导,治疗组在TNF-α诱导的同时,以不同浓度的积雪草苷、大黄素以及积雪草苷合大黄素进行干预,于24h后分别提取细胞RNA及上清,应用逆转录-聚合酶链反应(RT-PCR)和酶链免疫方法(ELISA)分别检测HPTECC3mRNA和蛋白的表达。
短句来源
    Results Compared with the blank control group,the expression of NF-κBp50,IκBαand IL-1β portein and mRNA of acute ischemic cardiac muscle were higher in the other groups(P<0.05).
    结果模型组及各治疗组与空白组比较NF-κBp50(细胞核)、IκBα(细胞浆)、IL-1β及其mRNA表达均显著增高(P<0.05)。
短句来源
    After 30-day,60-day and 90-day treatment and 2 weeks after suspension of medication,SDRS scores were lower in groups A and B as compared with those before treatment (P<0.01),and those in group A after 60-day and 90-day treatment and 2 weeks after suspension were lower than those in group B(P<0.05 or P<0.01).
    两组在治疗30、60、90 d和停药后2周的SDRS评分均较治疗前减少(P<0.01),且治疗组在治疗60、90 d和停药后2周的SDRS评分低于对照组(P<0.05或P<0.01)。
短句来源
    Meanwhile,the incidence of adverse reactions such as nausea and vertigo was less in group A than that in group B(P<0.01).
    另外,治疗组的恶心、头晕等不良反应发生率较对照组少(P<0.01)。
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  treatment groups
Tumor size was obviously reduced, and survival time clearly prolonged in the group with β-elemene combined with DC vaccine, in comparison to the other treatment groups and the control (P>amp;lt;0.01).
      
The Sprague-Dawley (SD) rats were randomly divided into different treatment groups (n = 6).
      
The levels of protein and ash in the whole body, carcass and viscera increased as MAB substitution in diets increased, whereas lipids and moisture remained consistent among all treatment groups.
      
As a result, it was determined that aqueous extracts reduced mitotic index and chromosome aberrations in treatment groups in comparison with controls.
      
Methods: Twenty rats were randomized into 4 treatment groups (n=5 in each group): control, ECT alone, hyperthermia alone and ETECT.
      
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  treated groups
The highest percentage (84.85%) of damaged DNA was shown in 5.0 mg/L Zn2+ group after 28 days exposure and the biggest TL/D value (2.50) in all treated groups after 35 days exposure.
      
The enrolled included control (basic chow), hyperlipidemia and fenofibrate-treated groups (high fat diet).
      
In addition to normal plants of both forms, plant regenerants with morphological deviations were present in ambiol-treated groups.
      
Plasma triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and apoA-I concentrations were markedly increased in T0901317-treated groups.
      
Cx43 level in losartan or ramipril treated groups was higher than that in control group (P>amp;lt;0.01, P>amp;lt;0.05), but lower than that in high-cholesterol diet groups (P>amp;lt;0.05, P>amp;lt;0.01).
      
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40 rabbits were divided randomly into 4 groups: ①uninfected experimental group treated with different total doses in various courses,②infected experimental group,③infected control group, and④ normal control group. Pathomorphology, immunofluorescence specific lymphocytic transformation test and skin test were used w find that the allergic reactions both type Ⅲ and Ⅳ play an important role in the pathogenesis of nithiocyamine induced hepatic lesions, also find especially in the uninfected experimental group,Some...

40 rabbits were divided randomly into 4 groups: ①uninfected experimental group treated with different total doses in various courses,②infected experimental group,③infected control group, and④ normal control group. Pathomorphology, immunofluorescence specific lymphocytic transformation test and skin test were used w find that the allergic reactions both type Ⅲ and Ⅳ play an important role in the pathogenesis of nithiocyamine induced hepatic lesions, also find especially in the uninfected experimental group,Some important pathological features,sacb as: hepatic autoimmune granulom (4/22)and cholangiolar proliferation with pericholangiolitis(21/22)etc. No significant differences could be found statistically (P>0.05), there fore the occurrence and the degree of various pathological changes have no definite interrelactionship with the dose and the duration of the drug.The hepatic lesions of the experimental animals with the exception of one rabbit were rather mild.

实验采用家兔40只,随机分成4组:①单纯服药组,用不同疗程和剂量;②感染治疗组;③感染对照组;④正常对照组,我们应用病理形态学、免疫荧光、特异性淋巴细胞转化试验和皮肤试验等项进行药物性肝损害发病机制的研究。实验结果表明本药所致肝损害主要是变态反应性(兼有Ⅲ及Ⅳ型)机制。我们看到实验动物肝内有重要的病理形态学变化,以单纯服药组较为明显,主要有肝自身免疫性肉芽肿(4/22),细胆管增生及其周围炎(21/22)等,分别经显著性检验,无显著差异(P>0.05),表明各项病变的发生及其程度与药量和疗程无平行关系。本实验组家兔肝脏病变除1只兔外均较轻。

The ability to transfer anti-tumor immunity by spleen RNA of tumor bearing donors was evaluated both in in vitro and in vivo experiments in animals and human patients. In in vitro test of mixed lymphocyte-tumor cells reaction, it was found that normal lymphocytes behaved like the tumor-sensitized lymphocytes after the preincubation with spleen RNA of mice bearing Sarcoma180 in blastogenic response to these tumor cells, and thus the mediation of anti-tumor immunological responsiveness by spleen RNA of tumor bearing...

The ability to transfer anti-tumor immunity by spleen RNA of tumor bearing donors was evaluated both in in vitro and in vivo experiments in animals and human patients. In in vitro test of mixed lymphocyte-tumor cells reaction, it was found that normal lymphocytes behaved like the tumor-sensitized lymphocytes after the preincubation with spleen RNA of mice bearing Sarcoma180 in blastogenic response to these tumor cells, and thus the mediation of anti-tumor immunological responsiveness by spleen RNA of tumor bearing mice were confirmed. In in vivo tests, both animal experiments in mice and immunotherapeutic treatment in human cancer patients demonstrated that a tumor inhibitory effect could be induced by the administration of spleen RNA from the donors bearing the appropriate tumor, while the RNAs from the respective normal spleens were ineffective. The results presented indicated that spleen RNA from tumor bearing donors might have the same biological activity in effecting the transfer of immunoreactivity against tumor as that of immune RNA from spleen cells of immunized animals. No visible suppressive effect on the immunological responsiveness by spleen RNA from tumor bearing donors had been detected in experiments so far conducted in our laboratory.

本文对带瘤小鼠及肿瘤患者的脾RNA的传递免疫反应的能力进行了实验研究。用淋巴细胞——肿瘤细胞混合培养法对带S_(180)小鼠的脾RNA进行的体外培养实验表明,正常小鼠的淋巴细胞与带S_(180)小鼠的脾RNA温育后可以转变成为对S_(180)瘤细胞致敏的淋巴细胞。表现为在混合淋巴细胞——瘤细胞培养中的淋转率的提高。这就说明带瘤鼠的脾RNA可以有正常淋巴细胞传递抗S_(180)免疫反应的功能。在小鼠的活体抑瘤实验中,带S_(180)小鼠的脾RNA可对接种S_(180)小鼠的肿瘤生长有33.0—66.9%的抑瘤率,用正常脾RNA则没有效果;同样,用从胃癌患者切除的脾脏中提取的RNA对胃癌患者进行免疫治疗时,治疗组的四年存活率可达47.1%,对照组则为22.7%,治疗组的几项免疫指标均较治疗前有所提高。上述各项体外及活体实验的结果都说明带瘤供体的脾RNA可以传递特异的抗肿瘤免疫反应的信息,其效应和前人所报告的从免疫动物脾中提取的免疫RNA是完全一致的。

observations on the experimental combined therapy with the estradiol, cepharan-thine, antibiotics, antihemorrhagics and general care in 55 severely irradiated dogs were made. The therapeutic effect proved to be satisfactory. The experiment was repeated for 5 times with the same result. In the therapeutic group, 26 of 30 dogs survived, while all in the control group died. The 30-days survival rate in the therapeutic group was 86.7%.The benefit and disadventage of the therapeutic regimens were discussed.

采用雌二醇合并千金藤素加上一般抗菌、抗出血措施,对经300 rad~(60)钴γ线照射、造成重度急性放射病的狗进行实验治疗,获得较高疗效:治疗组30只活存26只,对照组25只全部死亡,提高活存率86.7%。经5次实验,重覆性好。该治疗措施的主要特点是促使白细胞提前回升,减轻极期症状,使受照射动物较早进入恢复期。加之药物来源广、方法简便易行,附合实战要求。对出血和贫血的控制尚不理想,有待提高。

 
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