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   人类胃癌 的翻译结果: 查询用时:0.515秒
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人类胃癌
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  human gastric carcinoma
     Objective:To investigate the effect of ligand of peroxisome proliferators-activated receptorγ(PPARγ),15-deoxy-△~(12,14)prostaglandin J_2(15d-PGJ_2) on the growth of human gastric carcinoma MGC803 cells and its mechanism.
     目的:探讨过氧化物酶体增殖物激活受体γ(peroxisome proliferator activated receptorγ,PPARγ)的配体15-脱氧前列腺素J2(15-deoxy-△12,14-prostaglandin J2,15d-PGJ2)对人类胃癌MGC803细胞生长的影响及其机制。
短句来源
     Objective To investigate the expression of peroxisome proliferator-activated receptorγ(PPARγ) in human gastric carcinoma and the effect of its ligand 15-deoxy-△~(12,14)-Prostagliandxin J_(2)(15d-PGJ_(2)) on the growth of human gastric carcinoma MGC803 cells.
     目的探讨过氧化物酶体增殖激活物受体γ(PPARγ)在人类胃癌中表达的意义及其配体15-脱氧前列腺素J2(15d-PGJ2)对人类胃癌MGC803细胞生长的影响及机制。
短句来源
     A study on the loss of loci on chromosome8 in the human gastric carcinoma
     人类胃癌8号染色体等位基因缺失的研究
短句来源
     Objective:By examining the expression of the cyclin-dependent kinase inhibitor p27 and S-phase kinase-associated protein 2(Skp2) through mRNA and protein levels in human gastric carcinoma(GC), analyzed the correlationship between Skp2 gene and p27 gene;
     通过研究细胞周期素抑制因子p27与S相激酶相关蛋白(Skp2)两基因在人类胃癌组织中mRNA和蛋白两水平的表达差异性,分析Skp2与p27基因的相互关系及其与胃癌肿瘤直径、分化程度、浸润深度等临床特征之间的关系。
短句来源
     Gastrin/CCK-B receptors in an autocrine pathway may play an important role in the development and progression of gastric cancers. In the study, RT-PCR and sequencing were employed to detect the expression levels of CCK-B receptor, CCKBRi4sv and gastrin mRNAs in 30 human gastric carcinoma and their corresponding normal tissues, 10 gastritis and 2 autopsied normal stomach specimens as well as in a gastric carcinoma cell line SGC-7901 cells.
     本研究首先用RT-PCR及测序方法检测了30例人类胃癌组织及癌周正常胃粘膜、10例胃炎、2例尸检胃组织及胃癌细胞株SGC-7901中CCK-B受体、CCK-B受体的异位剪接变异体(intron 4-contained variant of cholecystokinin B receptor,CCKBRi4sv)及胃泌素基因的表达。
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  “人类胃癌”译为未确定词的双语例句
     Detection of EphB2 Mutation in Human Gastric Cancer by DHPLC
     DHPLC法检测人类胃癌组织中EphB2基因的突变
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     Objective:Our aim was to observe the expression of transforming growth factor beta I(TGF β 1)and transforming growth factor beta receptor I(TβR 1)gene in gastric cancer (GC)and its relationship with the degree of malignancy and lymphonode matastasis.
     目的 :观察转化生长因子β1 (TGF-β1 )及其受体 I(TβR1 )基因在人类胃癌组织中的表达及其与胃癌病理生物学行为的关系。
短句来源
     its activation3.Use reverse transcription polymerase chain reaction(RT-PCR) clone MMP14 hinge domain and incert it into vector pGBKT7.Test the relationship between ppGalNAc-T2 and MMP14 hinge domain by yeast two hybrid systems.
     3.利用RT-PCR方法从人类胃癌SGC7901细胞中克隆出基质金属蛋白酶14的铰链区,并用酵母双杂交方法验证ppGalNAcT2与MMP14的铰链区结构相互作用。
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     Conclusions The selective COX-2 inhibitor nimesulide can significantly inhibit development of gastric cancer and precancerous changes induced by ENNG in model of rat. This provides evidence that COX-2 inhibitors may have chemopreventive potential in human gastric cancer.
     结论 选择性COX 2抑制剂尼美舒利能有效抑制ENNG诱导的大鼠胃癌及癌前状态的发生 ,这为COX 2抑制剂对人类胃癌有潜在化学预防作用提供了证据。
短句来源
     Results:TGF β1 was detected in 43 of 50(86%)resected gastric carcinomas specimens. The level of TGF β1 were higher in advanced stage gastric carcinomas than early stage gastric carcinomas,P<0.05,and it was higher in lymphnode metastasis than in non metastasis,P<0.05.Conclusions:Human gastric carcinomas express TGF β1,and their expression significantly correlate with the development of gastric carcinoma the depth of invasion and lymphonde metastasis.
     结果50例胃癌组织中43例(86%)表达TGF-β1,TGF-β1在进展期胃癌中的表达水平高于早期胃癌(P<0.05),有淋巴结转移者高于无淋巴结转移者(P<0.05)。 结论人类胃癌表达TGF-β1,其表达与胃癌的发生、浸润与淋巴结转移有关。
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  相似匹配句对
     Genescan Analysis of Related Chromosomes in Human Primary Gastric Cancer
     人类原发性胃癌相关染色体基因扫描分析
短句来源
     Gastric cancer is one of the most common malignant tumors which are threatening human's health.
     胃癌是威胁人类健康的常见恶性肿瘤之一。
短句来源
     Human Sperm Bank,HSB
     人类精子库
     The Human's Box
     人类的盒子
短句来源
     Prevention and Treatment of Stomach Cancer
     胃癌的防治
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  human gastric carcinoma
Differences in expression and regulation between transformed cells of the human gastric carcinoma oncogene Ha-ras and the untran
      
In vitro antitumor activity of tumor-infiltrating lymphocytes from human gastric carcinoma
      
The results of present study indicate that TIL from human gastric carcinoma could be expanded and reach high levels of antitumor effector function in long-term cultures with rIL-2.
      
Effect of adenovirus-mediated p53 gene transfer on apoptosis and radiosensitivity of human gastric carcinoma cell lines
      
Objective: To evaluate the effect of adenovirus-mediated p53 gene (Adp53) on apoptosis and radiosensitivity of human gastric carcinoma cell lines.
      
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This article describes dietribntion and phenotype of GST-π in 38 cases of gastric carcinomas and 28 cases of gastric precancerous lesion and 22 cases of normal gastric mucous membrane. The results showed that positive substances for GSTπ staining were brown and were distributed incytop lasma. According to the characterastics of distribution in cytoplasma, it can be divided into cytoplasma type, periphery type, secretory type and ring cell type. The positive rates of GST-π in organ with gastric adenocarcinoma...

This article describes dietribntion and phenotype of GST-π in 38 cases of gastric carcinomas and 28 cases of gastric precancerous lesion and 22 cases of normal gastric mucous membrane. The results showed that positive substances for GSTπ staining were brown and were distributed incytop lasma. According to the characterastics of distribution in cytoplasma, it can be divided into cytoplasma type, periphery type, secretory type and ring cell type. The positive rates of GST-π in organ with gastric adenocarcinoma could reach more than 95%, the positive rates of GST-π in mucous of adenocarcinoma, ring cellular carcinoma and undifferentiated cancer wer low andits activitywas weakened. The- refore it is suggested that GST-π could beregarded as a type of new mark enzyme in gastric carcinoma and gastric premalignant states in human.

本文用对人胎盘型谷胱甘肽S-转移酶(GST-π)抗体的ABC法检查了38例胃癌和28例胃癌前期病变及22例正常胃粘膜。观察结果表明,GST-π阳性物质为棕色,分布于细胞浆内,根据其在细胞内分布的特点可分为胞质型、周边型、分泌型和印戒型。胃腺癌组织中GST-π的阳性率可达95%以上,胃粘膜的不典型增生和肠上皮化生组织中阳性率分别达100%和85%,且活性高,但粘液腺癌、印戒细胞癌和未分化癌组织中GST-π阳性率低,而且活性也低。作者认为GST-π可作为人类胃癌和胃癌前期病变的新的标志酶。

One hundred Wistar rats were given 100 μg/ml solution of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) orally, to establish the animal model gastric carcinoma. After the administration of MNNG solution for 9 months, 50/62 (80.7%) rats developed adenocarcinoma of the stomach. The diagnosis was based on the histoiogic appearances of the lesions. Macroscopically, all the carcinomas were of either polypoid or ulcerated pattern, and developed most frequently at the antrum along the lesser curvature. Microscopically,...

One hundred Wistar rats were given 100 μg/ml solution of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) orally, to establish the animal model gastric carcinoma. After the administration of MNNG solution for 9 months, 50/62 (80.7%) rats developed adenocarcinoma of the stomach. The diagnosis was based on the histoiogic appearances of the lesions. Macroscopically, all the carcinomas were of either polypoid or ulcerated pattern, and developed most frequently at the antrum along the lesser curvature. Microscopically, the gastric wall was involved in various depth. Papillary and tubular adenorcarcinoma were the main histological types while mucous adenorcarcinoma could be found in a few cases. These pathologic types were quite similar to those in the human being. It was concluded that a 9-month administration of 100 μg/ml MNNG solution to the inbred male Wistar rats was a favorite way to establish the animal model of gastric carcinoma.

作者自行合成N-甲基-N′-硝基-N-亚硝基胍(MNNG),并以100μg/mlMNNG稀释液喂以100只Wistar大鼠,以诱发胃癌。结果发现喂药6个月内,死亡20只,均无消化道癌肿发生;第7~8个月内,死亡18只,发生胃癌3只(16.7%);第9个月时,处死全部剩余大鼠共62只,其中50只发生胃癌(80.7%)。癌肿均位于腺胃小弯侧,多呈隆起结节型或溃疡型;组织学类型包括乳头状腺癌、分化或未分化管状腺痛;癌肿可侵犯胃壁各层,与人类胃癌病理特征颇为相似。作者还发现,纯系雄性Wistar大鼠是诱发实验性胃癌的理想对象。且以100μg/mlMNNG液,喂药9个月为适宜。

We report the affinity histochemical study on 22 gastric carcinomas in glandular stomach and 14 dysplastic gastric mucosas induced by MNNG and 17 normal gastrio mucosas in Wistar rats by using peanut agglutinin (PNA). The superficial epithelium of normal gastric mucosa in rats didn't bind PNA,the positive rate of fundus gland and pyloric gland were 89. 6% and 17. 6% respectively and the positive reaction was distributed diffusely in cytoplasm. Observing from fundus gland to pyloric gland,as well as,from neck,body...

We report the affinity histochemical study on 22 gastric carcinomas in glandular stomach and 14 dysplastic gastric mucosas induced by MNNG and 17 normal gastrio mucosas in Wistar rats by using peanut agglutinin (PNA). The superficial epithelium of normal gastric mucosa in rats didn't bind PNA,the positive rate of fundus gland and pyloric gland were 89. 6% and 17. 6% respectively and the positive reaction was distributed diffusely in cytoplasm. Observing from fundus gland to pyloric gland,as well as,from neck,body te bottom of the glands,the reaction of PNA binding was weakened progressively. The positive rate of PNA binding to gastric carcinomas and dysplastic glands in pyloric mucosa was higher than that of the normal gastric mucosa in the correspon ding regions. The staining of PNA binding was mainly distributed along the luminar surface of the glands or in the upper nuclear region of the cells. The results suggest that the distribution of PNA receptor in normal gastric mucosa of rats has a certain regularity and the experimental gastric carcinoma in rats has the same pathobiological feature as human gastric cancer.

本文应用花生凝集素(PNA)对17例正常大鼠胃粘膜以及MNNG诱发的22例大鼠腺胃胃癌和14例异型增生胃粘膜进行了亲合组织化学研究。正常大鼠胃粘膜表面上皮不结合PNA;胃底腺PNA结合阳性率为89.6%;幽门腺PNA结合阳性率是17.6%,弥漫分布于腺上皮胞浆内;从界嵴循胃底腺至胃窦幽门腺的顺序观察,PNA结合反应显示逐渐减弱趋势;胃底腺颈、体和底部细胞的PNA结合反应也显示逐渐减弱,大鼠腺胃幽门部胃癌及异型增生腺体的PNA阳性率比正常胃粘膜的相应部位高,PNA结合反应主要沿癌变腺体的腔膜面分布或定位子细胞核上区。本实验结果表明大鼠正常胃粘膜PNA受体的分布具有一定的规律性,大鼠实验性胃癌模型表现有人类胃癌相似的病理生物学特征。

 
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